Reaction

Drug Level Changed reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 627 reports · 9 co-occurring drugs

As of the last recalculation, Drug Level Changed appears in 627 FAERS reports alongside 9 co-occurring drug terms. The strongest observed disproportionality signal is EXTENDED PHENYTOIN SODIUM (PRR 100.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Extended Phenytoin Sodium47100.7101.0
Phenytoin2337.938.0
Valproic Acid2830.830.9
Propofol2725.625.6
Itraconazole823.023.0
Tenofovir Disoproxil Fumarate Tablets519.419.4
Ivacaftor312.612.6
Sofosbuvir610.210.2
Ledipasvir And Sofosbuvir46.96.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.