What this is: FAERS is a spontaneous, voluntary, unverified adverse-event reporting system. Disproportionality measures (PRR, ROR) flag reporting patterns worth investigating — they are not incidence rates and do not establish causation. Reporting is shaped by drug age on market, media attention, litigation, and indication severity, independent of true risk. Values are precomputed on a batch schedule; see "last recalculated" below. Grades for the clearest signals are on the causality assessment. How reliable are these statistics? See the validation against 485 known drug–event pairs (only 17% of classic PRR signals survive empirical calibration).

Causality assessment

Which FAERS signals hold up?

353 drug–reaction cards are written against Bradford Hill’s nine viewpoints, the FDA label, and a ClinicalTrials.gov check where a trial posted results. The newest 100 cards are marked draft until that prose is written. A PRR on this site is context for the grade, not the grade.

239 established 96 expected effect 14 contested 4 coding artifacts 100 drafts

Tardive dyskinesia Agranulocytosis Ranitidine and NDMA Newest batch

Open the assessment

Drug pages

Label screen and trial cross-check

Each of the 2,698 drug pages opens with the FDA label and PubChem (class, brands, indication, boxed warning), a seriousness and sex profile, and a screen for whether a strong signal is already labeled, the indication reported back, a coding artifact, or unlabeled. Signals also carry MGPS and BCPNN estimates beside PRR. Browse by drug class or head-to-head comparison.

That screen is text matching, not a causality judgement. Examples: clozapine, adalimumab, prednisone, ibuprofen.

Assessment on request

Need a pair nobody has written up?

OpenPV holds disproportionality statistics for 1.3 million drug–event pairs and written assessments for a few hundred of them. Sponsor one and an AI research agent drafts the Bradford Hill card from PubMed, the FDA label and ClinicalTrials.gov; every citation is re-fetched and title-matched before it publishes. The page is public and permanent, so one sponsor opens it for everyone, and you get the full report as a PDF.

Full pair $9 Comparison $12 Drug overview $35 Case worksheet free

You authorise the amount at request time and are charged only when the page is live. If the draft fails citation verification twice, nothing publishes and nothing is charged. A “contested” or “coding artifact” grade is a finding, not a refund. Not medical advice. There is also a free Naranjo and WHO-UMC case worksheet that publishes nothing.

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Total FAERS reports

Reaction terms tracked

Drugs with signals

Last recalculated

Top reactions by report volume

	Reaction	Reports	Co-occurring drugs	Top signal
1	Drug Ineffective	1,299,281	1,139	Gold (PRR 9.7)
2	Off Label Use	856,387	1,129	Infliximab-Dyyb (PRR 12.8)
3	Death	849,879	1,124	Sucroferric Oxyhydroxide (PRR 9.3)
4	Nausea	778,532	1,125	Trisodium Citrate Dihydrate (PRR 11.9)
5	Fatigue	766,588	1,121	Desoximetasone (PRR 12.9)
6	Diarrhoea	634,721	1,121	Trofinetide (PRR 17.8)
7	Headache	617,862	1,137	Caffeine Citrate (PRR 10.5)
8	Pain	607,158	1,158	Protamine Sulfate (PRR 19.2)
9	Dyspnoea	558,127	1,128	Isopropyl Alcohol Spray (PRR 13.6)
10	Dizziness	491,285	1,145	Trisodium Citrate Dihydrate (PRR 18.3)
11	Vomiting	462,654	1,121	Sodium Sulfate, Magnesium Sulfate, And Potassium Chloride (PRR 23.4)
12	Malaise	433,763	1,127	Coal Tar (PRR 18.3)
13	Rash	427,881	1,114	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 30.1)
14	Arthralgia	408,883	1,159	Escherichia Coli (PRR 28.0)
15	Pruritus	372,949	1,152	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 35.2)
16	Asthenia	371,081	1,116	Escherichia Coli (PRR 27.0)
17	Pyrexia	341,650	1,141	Isopropyl Alcohol Spray (PRR 19.6)
18	Fall	328,076	1,162	Escherichia Coli (PRR 35.8)
19	Pneumonia	318,973	1,120	Coal Tar (PRR 17.7)
20	Injection Site Pain	299,523	1,161	Kit For The Preparation Of Gallium Ga 68 Gozetotide Injection (PRR 46.1)
21	Condition Aggravated	297,981	1,153	Infliximab-Dyyb (PRR 26.5)
22	Pain In Extremity	291,273	1,173	Triclosan (PRR 20.6)
23	Anxiety	281,523	1,181	Talc (PRR 38.9)
24	Product Dose Omission Issue	280,971	1,194	Pexidartinib Hydrochloride (PRR 27.5)
25	Cough	276,106	1,145	Escherichia Coli (PRR 36.4)
26	Weight Decreased	275,349	1,145	Triclosan (PRR 24.6)
27	Insomnia	263,241	1,173	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 46.8)
28	Product Use In Unapproved Indication	241,070	1,167	Ibuprofen, Acetaminophen (PRR 53.4)
29	Feeling Abnormal	237,380	1,163	Estriol0.2% (PRR 20.1)
30	Abdominal Pain	229,419	1,132	Escherichia Coli (PRR 44.6)
31	Back Pain	229,409	1,133	Perflutren (PRR 38.8)
32	Decreased Appetite	228,553	1,128	Escherichia Coli (PRR 43.1)
33	Depression	225,508	1,171	Atazanavir Sulfate (PRR 24.5)
34	Incorrect Dose Administered	221,929	1,170	Tirzepatide (PRR 19.7)
35	Weight Increased	219,845	1,176	Triprolidine Hydrochloride (PRR 59.3)
36	Overdose	213,770	1,184	Hydrocodone Polistirex And Chlorpheniramine Polistirex (PRR 46.0)
37	Constipation	213,553	1,156	Phosphoric Acid (PRR 55.4)
38	Hypertension	209,236	1,132	Triclosan (PRR 36.0)
39	Abdominal Pain Upper	202,724	1,165	Escherichia Coli (PRR 45.0)
40	Erythema	202,577	1,137	Fluocinolone Acetonide, Hydroquinone, And Tretinoin (PRR 30.3)
41	Wrong Technique In Product Usage Process	199,314	1,145	Scopolamine Transdermal System (PRR 20.9)
42	Somnolence	198,390	1,174	Medicinal Massage Oil (PRR 66.0)
43	Hypotension	197,646	1,140	Acebutolol Hydrochloride (PRR 47.5)
44	Alopecia	194,180	1,168	Cetirizine Hydrochloride, Pseudoephedrine Hydrochloride (PRR 54.9)
45	Drug Hypersensitivity	191,655	1,185	Nickel (PRR 69.4)
46	Gait Disturbance	189,407	1,167	Triprolidine Hydrochloride (PRR 67.0)
47	Anaemia	188,336	1,139	Citric Acid (PRR 29.5)
48	Blood Glucose Increased	186,672	1,155	Insulin Lispro (PRR 39.4)
49	Product Use Issue	184,493	1,149	Potassium Phosphate, Dibasic (PRR 47.7)
50	Chest Pain	183,140	1,141	Estriol0.2% (PRR 25.5)
51	Hypersensitivity	182,912	1,156	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 57.6)
52	Nasopharyngitis	182,295	1,195	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 57.0)
53	Muscle Spasms	181,136	1,166	Gadoxetate Disodium (PRR 39.8)
54	No Adverse Event	175,026	1,177	Menthol And Lidocaine (PRR 113.2)
55	Covid-19	174,599	1,162	Nirmatrelvir And Ritonavir (PRR 57.6)
56	Inappropriate Schedule Of Product Administration	174,471	1,167	Tetrahydrozoline Hydrochloride (PRR 38.9)
57	Myocardial Infarction	173,520	1,118	Eptifibatide (PRR 32.4)
58	Urinary Tract Infection	167,830	1,118	Nitrofurantoin Monohydrate/Macrocrystalline (PRR 17.2)
59	Cerebrovascular Accident	167,800	1,114	Diphenhydramine Hydrochloride, Brompheniramine Maleate, And Dextromethorphan Hydrobromide (PRR 48.0)
60	Myalgia	167,738	1,138	Escherichia Coli (PRR 59.1)
61	Toxicity To Various Agents	165,620	1,169	Acebutolol Hydrochloride (PRR 47.8)
62	Drug Dose Omission	165,472	1,085	Cinacalcet Hydrochloride (PRR 24.8)
63	Abdominal Discomfort	164,952	1,184	Cetirizine Hydrochloride, Pseudoephedrine Hydrochloride (PRR 68.4)
64	Urticaria	164,230	1,176	Triprolidine Hydrochloride (PRR 81.5)
65	Tremor	164,054	1,158	Efinaconazole (PRR 10.1)
66	Drug Dependence	160,534	1,026	Oxycodone Hydrochloride (PRR 158.4)
67	Confusional State	159,773	1,160	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 64.2)
68	Drug Interaction	156,580	1,160	Serotonin (PRR 43.9)
69	Paraesthesia	155,629	1,168	Trisodium Citrate Dihydrate (PRR 114.5)
70	Peripheral Swelling	151,425	1,169	Chlorhexidine Gluconate And Isopropyl Alcohol (PRR 81.8)
71	Blood Pressure Increased	151,199	1,154	Escherichia Coli (PRR 66.2)
72	Hospitalisation	150,365	1,151	Ivacaftor (PRR 23.9)
73	Acute Kidney Injury	150,299	1,156	Omepraole, Sodium Bicarbonate (PRR 51.5)
74	Hypoaesthesia	147,881	1,181	Triclosan (PRR 49.3)
75	Infection	142,285	1,156	Sodium Borate (PRR 90.4)
76	Memory Impairment	135,741	1,174	Triclosan (PRR 37.4)
77	Vision Blurred	134,806	1,171	Escherichia Coli (PRR 61.4)
78	Neutropenia	133,702	1,168	Clozapine (PRR 27.1)
79	Product Quality Issue	133,032	1,145	Magnesium Salicylate (PRR 98.7)
80	Renal Failure	132,013	1,140	Protamine Sulfate (PRR 86.6)
81	Dehydration	131,636	1,126	Estriol0.2% (PRR 33.7)
82	Dry Skin	129,814	1,155	Adapalene (PRR 61.0)
83	Psoriasis	129,020	1,133	Coal Tar (PRR 87.2)
84	Hyperhidrosis	127,257	1,161	Almotriptan Malate (PRR 107.2)
85	Loss Of Consciousness	126,533	1,123	Fluorescein Sodium (PRR 13.3)
86	Injection Site Erythema	121,816	1,078	Rilonacept (PRR 20.0)
87	Visual Impairment	121,404	1,157	Aceclidine (PRR 59.9)
88	Oedema Peripheral	120,711	1,151	Triclosan (PRR 48.5)
89	Emotional Distress	119,903	1,157	Protamine Sulfate (PRR 66.9)
90	Joint Swelling	118,884	1,178	Triprolidine Hydrochloride (PRR 116.5)
91	Disease Progression	116,374	1,169	Tislelizumab-Jsgr (PRR 64.3)
92	Chills	115,872	1,146	Escherichia Coli (PRR 100.2)
93	Palpitations	115,461	1,165	Tetrahydrozoline Hydrochloride (PRR 53.6)
94	General Physical Health Deterioration	113,372	1,165	Bismuth Subnitrate (PRR 118.6)
95	Seizure	113,255	1,143	Fenfluramine (PRR 81.4)
96	Muscular Weakness	112,150	1,151	Triclosan (PRR 45.7)
97	Rheumatoid Arthritis	111,585	1,132	Cetirizine Hydrochloride, Pseudoephedrine Hydrochloride (PRR 98.8)
98	Asthma	110,622	1,193	Pyrilamine Maleate (PRR 149.7)
99	Influenza	110,352	1,148	Coal Tar (PRR 51.8)
100	Sepsis	110,128	1,153	Medicinal Massage Oil (PRR 120.7)
Browse all 10,143 reactions →

Top drugs by signal strength (max PRR)

	Drug	Max PRR	Flagged reactions	Total co-reports
1	Pseudoephedrine Hydrochloride	0	784	320,627
2	Pseudoephedrine Hcl	0	976	325,783
3	Diclofenac Potassium, Film Coated	0	979	243,167
4	Diclofenac Potassium Tablets	0	979	243,176
5	Gentamicin	0	1,119	50,450
6	Gentamicin Sulfate	0	1,159	60,401
7	Basiliximab	0	1,057	47,951
8	Tacrolimus	0	1,396	497,968
9	Belimumab	0	1,129	96,281
10	Epoetin Alfa	0	1,094	51,122
11	Etonogestrel And Ethinyl Estradiol	0	1,146	80,403
12	Cetuximab	0	1,074	85,215
13	Pegvaliase-Pqpz	0	482	18,823
14	Agalsidase Beta	0	1,002	27,268
15	Copper	830,735.0	999	151,174
16	Filgrastim	40,045.7	1,270	146,964
17	Ciclesonide	38,178.8	1,165	130,433
18	Dexlansoprazole	35,587.2	1,189	188,900
19	Methimazole	33,127.6	1,072	29,371
20	Temozolomide	32,563.2	1,047	64,154
21	Axicabtagene Ciloleucel	26,937.2	848	30,889
22	Finasteride	21,498.5	1,209	215,579
23	Theophylline	21,356.3	1,129	67,669
24	Theophylline Anhydrous	19,797.8	1,156	72,255
25	Micafungin Sodium	19,631.5	1,010	30,978
26	Epinephrine	19,013.4	1,230	274,261
27	Lifitegrast	18,530.4	993	43,588
28	Faricimab	18,227.7	465	16,601
29	Ampicillin	18,027.9	1,090	34,213
30	Ampicillin Sodium	18,027.9	1,090	34,213
31	Dabigatran Etexilate Mesylate	17,539.0	1,230	173,374
32	Cytarabine	16,580.1	1,220	210,853
33	Canakinumab	15,382.6	1,006	40,722
34	Ceftriaxone Sodium	13,949.6	1,259	142,548
35	Pantoprazole Sodium	13,745.0	1,190	834,345
36	Fluticasone Furoate	13,737.9	1,108	70,959
37	Etoposide	13,540.8	1,244	234,517
38	Treprostinil	13,408.8	1,239	508,089
39	Valganciclovir	13,236.3	1,126	72,801
40	Valganciclovir Hydrochloride	13,236.3	1,125	72,794
41	Ivacaftor	13,096.6	693	14,110
42	Lansoprazole	13,077.1	1,201	807,212
43	Bleomycin Sulfate	12,586.7	1,005	30,693
44	Iohexol	12,545.2	996	25,725
45	Dextrose	12,142.9	1,092	61,251
46	Heparin Sodium	12,099.2	1,090	54,593
47	Dupilumab	12,087.9	1,268	1,231,391
48	Thiotepa	11,982.0	998	33,293
49	Dextrose Monohydrate	11,964.5	1,089	61,684
50	Levonorgestrel	11,640.9	1,249	465,560
51	Anakinra	11,473.4	1,097	102,833
52	Sodium Bicarbonate	10,729.1	1,246	107,232
53	Sodium Bicarbonate Injection,	10,729.1	1,246	107,224
54	Mepolizumab	10,447.2	1,202	321,903
55	Posaconazole Delayed-Release	10,418.6	1,026	40,511
56	Cenegermin-Bkbj	10,319.7	454	31,793
57	Methylprednisolone Acetate	9,815.6	1,091	80,625
58	Dimenhydrinate	9,761.2	1,170	108,920
59	Tiotropium Bromide Inhalation Spray	9,280.9	1,025	44,216
60	Rosuvastatin Calcium	8,855.0	1,217	175,009
61	Zidovudine	8,777.7	1,047	50,602
62	Medroxyprogesterone Acetate	8,752.0	1,181	106,977
63	Esomeprazole Magnesium	8,672.9	1,184	946,832
64	Inclisiran	8,647.8	855	22,830
65	Busulfan	8,591.8	1,024	56,495
66	Misoprostol	8,545.8	1,051	35,236
67	Moxifloxacin	8,120.9	1,133	87,212
68	Goserelin	7,746.2	1,101	49,236
69	Nevirapine	7,687.1	1,006	29,294
70	Sevoflurane	7,509.8	999	23,341
71	Pegaspargase	7,362.4	1,007	44,116
72	Posaconazole	7,039.8	1,061	54,712
73	Sirolimus	6,947.7	1,071	44,254
74	Doxazosin Mesylate	6,905.5	1,207	135,320
75	Dabigatran Etexilate	6,875.8	1,249	193,276
76	Dutasteride	6,823.2	1,029	44,039
77	Cariprazine	6,705.2	995	25,037
78	Prednisolone Acetate	6,701.8	1,074	34,998
79	Infliximab-Dyyb	6,439.3	1,169	224,921
80	Peginterferon Beta-1A	6,347.8	995	35,477
81	Raltegravir	6,298.0	1,084	55,718
82	Travoprost	6,252.6	996	22,786
83	Minocycline	6,245.4	1,101	96,086
84	Tolvaptan	6,212.1	1,015	44,798
85	Drs. Clotrimazole	6,149.2	1,158	58,345
86	Family Wellness Clotrimazole	6,149.2	1,156	58,337
87	Blinatumomab	6,147.7	1,000	29,857
88	Clotrimazole Topical	6,146.6	1,160	58,369
89	Clozapine	6,133.0	1,279	364,756
90	Candesartan Cilexetil	6,060.9	1,212	135,455
91	Daptomycin	6,013.5	1,000	25,816
92	Omeprazole Magnesium	6,006.8	1,148	1,697,357
93	Phytonadione	5,908.3	1,116	47,803
94	Ritonavir 100 Mg	5,791.8	1,074	48,538
95	Clotrimazole	5,786.4	1,165	61,623
96	Abacavir Sulfate	5,735.5	1,044	52,005
97	Mometasone	5,668.3	1,216	103,364
98	Tamsulosin Hydrochloride	5,604.5	1,178	90,097
99	Avapritinib	5,582.9	1,001	42,548
100	Irbesartan	5,487.1	1,179	181,121
Browse all 3,600 drugs →