Reaction

Painful Defaecation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 695 reports · 5 co-occurring drugs

As of the last recalculation, Painful Defaecation appears in 695 FAERS reports alongside 5 co-occurring drug terms. The strongest observed disproportionality signal is PEGINTERFERON ALFA-2A (PRR 51.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Peginterferon Alfa-2A8251.451.4
Ribavirin8042.042.0
Orlistat2428.728.7
Loratadine And Pseudoephedrine Sulfate311.311.3
Exenatide137.57.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.