Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted): side effects, ingredients & package insert

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) ingredients (FDA package insert, Section 11)

Per-dose composition as stated in the prescribing information; verified 2026-07-09. Click an ingredient for every vaccine that contains it.

Note: Protein subunit + Matrix-M adjuvant — no mRNA, no LNP.

Source: FDA package insert. Formulations change — re-verify before clinical use.

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) side effects: where the data is

Reported reactions for Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) and the other COVID-19 products are compiled on the COVID-19 vaccine page: pre-licensure trial reactogenicity, VAERS report counts, and international databases (Canada Vigilance, EudraVigilance, Lareb, VigiAccess). Those counts are spontaneous reports with no denominator — a report does not establish that the vaccine caused the event.

• Pre-licensure clinical trial data
• Post-licensure surveillance (VAERS and international)
• Documented adverse events and causality assessment
• Vaccine Injury Table (VICP) — compensable injuries

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) lot number lookup

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) vs Comirnaty (Pfizer-BioNTech COVID-19 Vaccine, mRNA) vs Spikevax (Moderna COVID-19 Vaccine, mRNA)

All licensed COVID-19 vaccine products side by side. Differences in platform, adjuvant and route are the usual reasons one is chosen over another; efficacy and safety comparisons belong to the trial and surveillance sections of the COVID-19 vaccine page.

Schedule and age range

Licensed ages and the recommended series for COVID-19 vaccines are on the COVID-19 vaccine page; how 31 countries schedule it is on COVID-19 schedule by country. Always confirm the product-specific age range in the current package insert.

Common questions about Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted)

What are the side effects of Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted)?

Common reactions listed in the Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) package insert are injection-site pain, redness or swelling and short-lived systemic symptoms such as fever, tiredness or irritability. Rarer events and the reported counts from VAERS and international databases are on the COVID-19 vaccine page; counts are reports, not rates, and do not prove the vaccine caused the event.

What is in Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted)?

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) contains SARS-CoV-2 recombinant spike protein as antigen; adjuvant: Matrix-M; it is preservative-free. Excipients: Polysorbate 80, Sodium chloride and buffer salts. Amounts per dose are in the table above, taken from Section 11 of the FDA package insert (verified 2026-07-09).

Where is the Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) package insert?

The FDA-licensed prescribing information for Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) is published by Novavax, Inc. and the FDA; the source used for this page is https://www.fda.gov/vaccines-blood-biologics/vaccines/nuvaxovid. Formulations change, so re-verify the current insert before clinical use.

How does Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) compare with Comirnaty (Pfizer-BioNTech COVID-19 Vaccine, mRNA)?

Nuvaxovid (Novavax COVID-19 Vaccine, Adjuvanted) (Novavax, Inc.) uses a recombinant protein platform with adjuvant Matrix-M, given intramuscular; Comirnaty (Pfizer-BioNTech COVID-19 Vaccine, mRNA) (Pfizer Inc. / BioNTech) uses mrna with adjuvant none. Both are licensed COVID-19 vaccines; the comparison table above lists every product.