Amlodipine vs Candesartan: side effects in FDA adverse event reports
At a glance
| Amlodipine | Candesartan | |
|---|---|---|
| Drug class | – | – |
| Brand names | Katerzia | – |
| FAERS reports | 267,918 | 35,463 |
| Serious | 77% | 96% |
| Death outcome | 29,515 | 4,872 |
| Boxed warning | No | Yes FETAL TOXICITY When pregnancy is detected, discontinue candesartan cilexetil tablets as soon as possible. [see Warnings and Precautions ( 5.1 ) and Use in Speci |
Signals both drugs share
| Reaction | Amlodipine | Candesartan | Label screen (A / B) |
|---|---|---|---|
| Carotid artery thrombosis | 164 · PRR 18.4 | 113 · PRR 90.2 | Not in label — unassessed / Not in label — unassessed |
Labeled signals distinctive to Amlodipine
- None stood out among the strongest labeled signals.
Labeled signals distinctive to Candesartan
- None stood out among the strongest labeled signals.
Common questions
Which has more reported side effects, Amlodipine or Candesartan?
Amlodipine has 267,918 FAERS reports and Candesartan 35,463. More reports does not mean more dangerous: volume follows how widely and how long a drug has been used, prescription vs over-the-counter status, and publicity. The seriousness share (77% vs 96%) is a better like-for-like signal of the kind of problems reported.
Which side effects do Amlodipine and Candesartan share?
Both drugs carry disproportionality signals for carotid artery thrombosis. Shared signals often reflect a shared drug class or the condition both are used for.
Is Amlodipine or Candesartan safer?
FAERS cannot answer that: it has no denominator and no comparator. Use this page to see which risks are already on each label and which signals are unlabeled, then check the prescribing information and your clinician for your situation.
Sources: openFDA FAERS pair statistics (OpenPV build 2026-09-14), FDA labels via openFDA, openFDA count queries for seriousness and deaths. Pair chosen because it is a commonly searched comparison. Generated 2026-10-08.