Amlodipine vs Diltiazem: side effects in FDA adverse event reports
At a glance
| Amlodipine | Diltiazem | |
|---|---|---|
| Drug class | – | – |
| Brand names | Katerzia | Diltiazem Hydrochloride |
| FAERS reports | 267,918 | 34,205 |
| Serious | 77% | 74% |
| Death outcome | 29,515 | 5,131 |
| Boxed warning | No | No |
Signals both drugs share
No strong shared signal after removing coding and lab terms.
Labeled signals distinctive to Amlodipine
- None stood out among the strongest labeled signals.
Labeled signals distinctive to Diltiazem
- None stood out among the strongest labeled signals.
Common questions
Which has more reported side effects, Amlodipine or Diltiazem?
Amlodipine has 267,918 FAERS reports and Diltiazem 34,205. More reports does not mean more dangerous: volume follows how widely and how long a drug has been used, prescription vs over-the-counter status, and publicity. The seriousness share (77% vs 74%) is a better like-for-like signal of the kind of problems reported.
Which side effects do Amlodipine and Diltiazem share?
They share no strong flagged signal after artifacts and lab terms are removed.
Is Amlodipine or Diltiazem safer?
FAERS cannot answer that: it has no denominator and no comparator. Use this page to see which risks are already on each label and which signals are unlabeled, then check the prescribing information and your clinician for your situation.
Sources: openFDA FAERS pair statistics (OpenPV build 2026-09-14), FDA labels via openFDA, openFDA count queries for seriousness and deaths. Pair chosen because it is a commonly searched comparison. Generated 2026-10-08.