Lisinopril vs Propranolol: side effects in FDA adverse event reports
At a glance
| Lisinopril | Propranolol | |
|---|---|---|
| Drug class | – | – |
| Brand names | – | – |
| FAERS reports | 304,208 | 71,644 |
| Serious | 61% | 70% |
| Death outcome | 25,263 | 7,184 |
| Boxed warning | Yes FETAL TOXICITY See full prescribing information for complete boxed warning. When pregnancy is detected, discontinue lisinopril as soon as possible. ( 5.1 ) Drug | No |
Signals both drugs share
No strong shared signal after removing coding and lab terms.
Labeled signals distinctive to Lisinopril
- Chronic kidney disease — n=9,125, PRR 9.2 Labeled adverse reaction
- Angioedema — n=6,693, PRR 12.2 Labeled — boxed warning
- Intestinal angioedema — n=265, PRR 86.6 Labeled — boxed warning
- Subcutaneous drug absorption impaired — n=203, PRR 40.6 Labeled (related wording)
Labeled signals distinctive to Propranolol
- Cardiogenic shock — n=428, PRR 9.0 Labeled adverse reaction
Common questions
Which has more reported side effects, Lisinopril or Propranolol?
Lisinopril has 304,208 FAERS reports and Propranolol 71,644. More reports does not mean more dangerous: volume follows how widely and how long a drug has been used, prescription vs over-the-counter status, and publicity. The seriousness share (61% vs 70%) is a better like-for-like signal of the kind of problems reported.
Which side effects do Lisinopril and Propranolol share?
They share no strong flagged signal after artifacts and lab terms are removed.
Is Lisinopril or Propranolol safer?
FAERS cannot answer that: it has no denominator and no comparator. Use this page to see which risks are already on each label and which signals are unlabeled, then check the prescribing information and your clinician for your situation.
Sources: openFDA FAERS pair statistics (OpenPV build 2026-09-14), FDA labels via openFDA, openFDA count queries for seriousness and deaths. Pair chosen because it is a commonly searched comparison. Generated 2026-10-08.