Drug

Adaplane 0.1%

51 flagged reaction(s) · 7,402 total co-reports · max PRR 43.0

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Skin Irritation	483	43.0	47.3	signal
2	Skin Burning Sensation	491	28.1	30.9	signal
3	Acne	464	24.8	27.1	signal
4	Dry Skin	798	24.7	29.0	signal
5	Therapy Cessation	227	18.0	18.8	signal
6	Pain Of Skin	91	13.7	13.9	signal
7	Skin Exfoliation	271	13.2	13.9	signal
8	Scar	41	9.7	9.7	signal
9	Erythema	402	7.9	8.5	signal
10	Drug Ineffective	2,412	7.4	13.0	signal
11	Skin Reaction	25	7.2	7.2	signal
12	Application Site Irritation	20	6.5	6.5	signal
13	Application Site Pain	31	5.7	5.7	signal
14	Dermatitis	29	5.7	5.7	signal
15	Condition Aggravated	416	5.6	6.0	signal
16	Therapeutic Response Decreased	77	5.2	5.2	signal
17	Application Site Erythema	32	4.9	4.9	signal
18	Therapeutic Product Effect Incomplete	76	4.3	4.4	signal
19	Skin Fissures	20	4.3	4.3	signal
20	Scab	12	4.3	4.3	signal
21	Hypersensitivity	166	3.6	3.7	signal
22	Therapeutic Response Unexpected	40	3.6	3.6	signal
23	Rash Macular	27	3.1	3.1	signal
24	Rash	336	3.1	3.3	signal
25	Application Site Rash	10	2.9	2.9	signal
26	Rash Maculo-papular	16	2.9	2.9	signal
27	Adverse Reaction	9	2.7	2.7	signal
28	Skin Haemorrhage	9	2.5	2.5	signal
29	Application Site Pruritus	14	2.5	2.5	signal
30	Swelling Face	40	2.5	2.5	signal
31	Rash Erythematous	28	2.4	2.4	signal
32	Folliculitis	6	2.3	2.3	no signal
33	Dermatitis Allergic	7	2.3	2.3	no signal
34	Drug Effective For Unapproved Indication	16	2.2	2.2	signal
35	Skin Discolouration	25	2.2	2.2	signal
36	Eye Swelling	20	2.2	2.2	signal
37	Burning Sensation	35	2.0	2.0	signal
38	Sleep Disorder Due To A General Medical Condition	7	1.7	1.8	no signal
39	Product Packaging Issue	4	1.7	1.7	no signal
40	Photosensitivity Reaction	7	1.7	1.7	no signal
41	Inappropriate Schedule Of Product Administration	73	1.7	1.7	no signal
42	Drug Effect Less Than Expected	5	1.4	1.4	no signal
43	Abortion Induced	3	1.3	1.3	no signal
44	Product Substitution Issue	17	1.2	1.2	no signal
45	Exposure During Pregnancy	18	1.2	1.2	no signal
46	Dermatitis Atopic	14	1.1	1.1	no signal
47	Bipolar Disorder	3	1.1	1.1	no signal
48	Eye Irritation	15	1.1	1.1	no signal
49	Expired Product Administered	8	1.0	1.0	no signal
50	Drug Dispensing Error	3	0.8	0.8	no signal
51	Multiple Fractures	3	0.7	0.7	no signal