Drug
Alfuzosin Hydrochloride
Important: Reactions below are the flagged terms from this drug’s
FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate
disproportionality in spontaneous reporting, not causation.
Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
| Reaction | Co-reports (a) | PRR | ROR | Signal | |
|---|---|---|---|---|---|
| 1 | Hepatic Cytolysis | 42 | 30.4 | 30.9 | signal |
| 2 | Inappropriate Antidiuretic Hormone Secretion | 18 | 15.6 | 15.7 | signal |
| 3 | Cholestasis | 32 | 14.8 | 15.0 | signal |
| 4 | Product Administration Error | 30 | 13.2 | 13.4 | signal |
| 5 | Pancreatitis Acute | 30 | 11.9 | 12.0 | signal |
| 6 | Poisoning Deliberate | 12 | 11.4 | 11.4 | signal |
| 7 | Toxic Skin Eruption | 13 | 11.3 | 11.4 | signal |
| 8 | Hyperkalaemia | 41 | 10.4 | 10.5 | signal |
| 9 | Agranulocytosis | 20 | 9.5 | 9.6 | signal |
| 10 | Micturition Urgency | 12 | 9.3 | 9.4 | signal |
| 11 | Product Dispensing Error | 23 | 9.3 | 9.4 | signal |
| 12 | Dizziness Postural | 10 | 9.2 | 9.2 | signal |
| 13 | Toxic Epidermal Necrolysis | 14 | 8.2 | 8.2 | signal |
| 14 | Sinus Bradycardia | 8 | 7.3 | 7.3 | signal |
| 15 | Hyponatraemia | 46 | 7.2 | 7.3 | signal |
| 16 | Coma | 36 | 6.7 | 6.7 | signal |
| 17 | Urinary Retention | 25 | 6.6 | 6.7 | signal |
| 18 | Altered State Of Consciousness | 16 | 6.5 | 6.6 | signal |
| 19 | Erectile Dysfunction | 19 | 6.5 | 6.5 | signal |
| 20 | Hepatocellular Injury | 10 | 6.2 | 6.2 | signal |
| 21 | Hypothermia | 7 | 6.1 | 6.1 | signal |
| 22 | Orthostatic Hypotension | 12 | 6.1 | 6.1 | signal |
| 23 | Pneumonia Aspiration | 17 | 6.0 | 6.0 | signal |
| 24 | Rash Maculo-papular | 15 | 6.0 | 6.0 | signal |
| 25 | Ventricular Extrasystoles | 7 | 5.9 | 5.9 | signal |
| 26 | Photosensitivity Reaction | 11 | 5.9 | 5.9 | signal |
| 27 | Clostridium Difficile Colitis | 7 | 5.8 | 5.8 | signal |
| 28 | Therapy Non-responder | 29 | 5.7 | 5.8 | signal |
| 29 | Drug Interaction | 102 | 5.7 | 5.9 | signal |
| 30 | Bone Marrow Failure | 13 | 5.6 | 5.6 | signal |
| 31 | Expired Product Administered | 21 | 5.6 | 5.6 | signal |
| 32 | Bronchospasm | 9 | 5.5 | 5.6 | signal |
| 33 | Bladder Disorder | 6 | 5.3 | 5.3 | signal |
| 34 | Lower Respiratory Tract Infection | 27 | 5.2 | 5.3 | signal |
| 35 | Tubulointerstitial Nephritis | 11 | 5.2 | 5.2 | signal |
| 36 | Presyncope | 14 | 5.1 | 5.1 | signal |
| 37 | Multiple Organ Dysfunction Syndrome | 16 | 5.0 | 5.1 | signal |
| 38 | Acute Kidney Injury | 87 | 5.0 | 5.2 | signal |
| 39 | Dyspnoea Exertional | 21 | 4.9 | 5.0 | signal |
| 40 | Haematuria | 19 | 4.9 | 4.9 | signal |
| 41 | Vertigo | 33 | 4.8 | 4.8 | signal |
| 42 | Hypertensive Crisis | 6 | 4.7 | 4.7 | signal |
| 43 | Thinking Abnormal | 10 | 4.7 | 4.7 | signal |
| 44 | Lactic Acidosis | 17 | 4.7 | 4.7 | signal |
| 45 | Hallucination, Visual | 11 | 4.6 | 4.6 | signal |
| 46 | Multi-organ Failure | 9 | 4.5 | 4.5 | signal |
| 47 | Ischaemic Stroke | 9 | 4.4 | 4.4 | signal |
| 48 | Psychomotor Hyperactivity | 8 | 4.2 | 4.2 | signal |
| 49 | Blood Creatine Phosphokinase Increased | 14 | 4.2 | 4.2 | signal |
| 50 | Disorientation | 19 | 4.2 | 4.2 | signal |
| 51 | Hot Flush | 36 | 4.2 | 4.3 | signal |
| 52 | Electrocardiogram Qt Prolonged | 17 | 4.2 | 4.2 | signal |
| 53 | Hepatitis | 12 | 4.1 | 4.1 | signal |
| 54 | Hallucination | 35 | 4.1 | 4.2 | signal |
| 55 | Bradycardia | 24 | 4.0 | 4.0 | signal |
| 56 | Tooth Disorder | 10 | 3.9 | 4.0 | signal |
| 57 | Status Epilepticus | 5 | 3.9 | 3.9 | signal |
| 58 | Sputum Discoloured | 4 | 3.7 | 3.7 | signal |
| 59 | Drug Level Increased | 7 | 3.7 | 3.7 | signal |
| 60 | Cardiogenic Shock | 6 | 3.7 | 3.7 | signal |
| 61 | Posterior Reversible Encephalopathy Syndrome | 4 | 3.7 | 3.7 | signal |
| 62 | Cytokine Release Syndrome | 8 | 3.7 | 3.7 | signal |
| 63 | Cerebral Haemorrhage | 15 | 3.7 | 3.7 | signal |
| 64 | Myoclonus | 5 | 3.7 | 3.7 | signal |
| 65 | International Normalised Ratio Increased | 12 | 3.7 | 3.7 | signal |
| 66 | Stevens-johnson Syndrome | 9 | 3.6 | 3.6 | signal |
| 67 | Infusion Site Pain | 5 | 3.4 | 3.5 | signal |
| 68 | Contraindicated Product Administered | 11 | 3.2 | 3.2 | signal |
| 69 | Extrapyramidal Disorder | 9 | 3.2 | 3.2 | signal |
| 70 | Drug Reaction With Eosinophilia And Systemic Symptoms | 9 | 3.1 | 3.1 | signal |
| 71 | Subdural Haematoma | 5 | 3.1 | 3.1 | signal |
| 72 | Delusion | 5 | 2.8 | 2.8 | signal |
| 73 | Product Use Complaint | 5 | 2.8 | 2.8 | signal |
| 74 | Tendonitis | 5 | 2.8 | 2.8 | signal |
| 75 | Hernia | 6 | 2.7 | 2.7 | signal |
| 76 | Product Substitution Issue | 17 | 2.6 | 2.6 | signal |
| 77 | Prostatic Specific Antigen Increased | 4 | 2.5 | 2.5 | no signal |
| 78 | Product Storage Error | 24 | 2.4 | 2.5 | signal |
| 79 | Product Dose Omission In Error | 7 | 2.3 | 2.3 | no signal |
| 80 | Sexual Dysfunction | 3 | 2.3 | 2.3 | no signal |
| 81 | Mood Swings | 8 | 2.2 | 2.2 | signal |
| 82 | Product Availability Issue | 5 | 2.0 | 2.0 | no signal |
| 83 | Exposure Via Skin Contact | 5 | 1.9 | 1.9 | no signal |
| 84 | Aggression | 11 | 1.9 | 1.9 | no signal |
| 85 | Pulmonary Arterial Hypertension | 3 | 1.8 | 1.8 | no signal |
| 86 | Product Physical Issue | 4 | 1.8 | 1.8 | no signal |
| 87 | Suicide Attempt | 11 | 1.6 | 1.6 | no signal |
| 88 | Gynaecomastia | 5 | 1.4 | 1.4 | no signal |
| 89 | Intentional Overdose | 10 | 1.4 | 1.4 | no signal |
| 90 | Intentional Self-injury | 3 | 1.3 | 1.3 | no signal |
| 91 | Prostate Cancer | 11 | 1.2 | 1.2 | no signal |
| 92 | Drug Abuse | 9 | 0.9 | 0.9 | no signal |
| 93 | Bladder Cancer | 5 | 0.7 | 0.7 | no signal |
| 94 | Device Leakage | 3 | 0.6 | 0.6 | no signal |
| 95 | Wrong Technique In Device Usage Process | 3 | 0.6 | 0.6 | no signal |