OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Aliskiren

147 flagged reaction(s) · 14,813 total co-reports · max PRR 170.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Ocular Discomfort 196 170.5 186.5 signal
2 Generalised Oedema 196 150.0 164.1 signal
3 Affect Lability 152 148.1 158.7 signal
4 Motor Dysfunction 150 139.6 149.4 signal
5 Muscle Spasticity 150 113.5 121.5 signal
6 Head Discomfort 193 102.7 112.2 signal
7 Coordination Abnormal 152 101.4 108.7 signal
8 Hemiparesis 156 85.7 91.9 signal
9 Altered State Of Consciousness 192 83.4 91.0 signal
10 Photophobia 158 79.1 85.0 signal
11 Presyncope 192 74.2 81.0 signal
12 Haematemesis 201 73.9 81.0 signal
13 Diplopia 189 68.0 74.1 signal
14 Eating Disorder 149 65.1 69.6 signal
15 Ascites 194 61.6 67.2 signal
16 Sinus Congestion 88 60.7 63.1 signal
17 Skin Haemorrhage 90 58.2 60.6 signal
18 Abortion Induced 58 57.4 58.9 signal
19 Haematuria 197 53.6 58.6 signal
20 Aphasia 155 47.7 51.1 signal
21 Respiratory Tract Congestion 80 46.9 48.6 signal
22 Diabetes Mellitus Inadequate Control 84 44.2 45.9 signal
23 Blindness 192 43.9 47.9 signal
24 Cardio-respiratory Arrest 197 43.6 47.7 signal
25 Sinus Disorder 88 41.3 43.0 signal
26 Dysarthria 161 39.9 42.8 signal
27 Coma 194 37.9 41.4 signal
28 Tinnitus 187 37.8 41.2 signal
29 Sneezing 89 37.1 38.5 signal
30 Angina Pectoris 111 35.8 37.6 signal
31 Eye Pain 197 33.2 36.3 signal
32 Cystitis 84 24.4 25.3 signal
33 Tachycardia 213 22.3 24.5 signal
34 Syncope 233 21.6 24.0 signal
35 Hyperkalaemia 76 20.2 20.9 signal
36 Blood Pressure Increased 305 18.5 21.2 signal
37 Sepsis 205 17.1 18.7 signal
38 Premature Baby 53 16.3 16.7 signal
39 Chills 202 16.0 17.5 signal
40 Hypertensive Crisis 19 15.8 15.9 signal
41 Dysphagia 148 14.5 15.5 signal
42 Cardiac Failure 121 14.0 14.7 signal
43 Glomerular Filtration Rate Decreased 18 13.8 13.9 signal
44 Blood Urea Increased 25 13.8 13.9 signal
45 Blood Creatinine Increased 97 13.8 14.3 signal
46 Myocardial Ischaemia 17 13.8 13.9 signal
47 Ventricular Tachycardia 24 13.4 13.6 signal
48 Rhinorrhoea 90 13.0 13.5 signal
49 Foetal Exposure During Pregnancy 113 12.9 13.5 signal
50 Muscular Weakness 157 12.8 13.7 signal
51 Cataract 73 11.4 11.8 signal
52 Cardiomegaly 15 11.2 11.3 signal
53 Vision Blurred 164 11.1 11.9 signal
54 Eyelid Oedema 14 11.1 11.2 signal
55 Myalgia 200 10.9 11.9 signal
56 Renal Failure Acute 50 10.8 11.0 signal
57 Cognitive Disorder 54 10.8 11.0 signal
58 Glycosylated Haemoglobin Increased 29 10.7 10.8 signal
59 Cerebrovascular Accident 192 10.5 11.4 signal
60 Fall 375 10.5 12.4 signal
61 Blood Potassium Increased 18 10.3 10.4 signal
62 Confusional State 176 10.1 10.9 signal
63 Skin Exfoliation 89 9.9 10.3 signal
64 Premature Delivery 17 9.9 9.9 signal
65 Cough 294 9.8 11.1 signal
66 Medication Error 58 9.7 9.9 signal
67 Gastrointestinal Disorder 91 9.6 9.9 signal
68 Influenza Like Illness 85 9.5 9.9 signal
69 Depressed Mood 54 9.5 9.7 signal
70 Somnolence 205 9.5 10.3 signal
71 Asthenia 380 9.4 11.1 signal
72 Cardiogenic Shock 14 9.1 9.2 signal
73 Impaired Work Ability 21 9.1 9.2 signal
74 Treatment Noncompliance 53 9.1 9.2 signal
75 Coronary Artery Disease 29 8.8 8.9 signal
76 Decreased Appetite 220 8.8 9.7 signal
77 Dizziness Postural 9 8.7 8.7 signal
78 Sudden Death 10 8.7 8.7 signal
79 Abdominal Pain Upper 189 8.5 9.2 signal
80 Haematocrit Decreased 18 8.4 8.4 signal
81 Drug Interaction 142 8.3 8.8 signal
82 Oedema Peripheral 109 8.3 8.6 signal
83 Mitral Valve Incompetence 10 8.2 8.2 signal
84 Abdominal Pain 203 8.1 8.8 signal
85 Ventricular Extrasystoles 9 8.0 8.1 signal
86 Renal Impairment 72 8.0 8.2 signal
87 Amnesia 55 7.8 8.0 signal
88 Arthritis 66 7.8 8.0 signal
89 Chest Discomfort 84 7.6 7.9 signal
90 Tachypnoea 11 7.5 7.6 signal
91 Hepatomegaly 8 7.5 7.5 signal
92 Pyrexia 279 7.5 8.4 signal
93 Mobility Decreased 57 7.4 7.6 signal
94 Contusion 75 7.2 7.5 signal
95 Cerebral Infarction 19 7.2 7.3 signal
96 Sinusitis 78 7.0 7.3 signal
97 Influenza 84 7.0 7.2 signal
98 Orthostatic Hypotension 13 6.9 6.9 signal
99 Acute Myocardial Infarction 22 6.9 7.0 signal
100 Ventricular Fibrillation 8 6.7 6.7 signal
101 Insomnia 190 6.6 7.1 signal
102 Malaise 306 6.5 7.3 signal
103 Rheumatoid Arthritis 78 6.4 6.6 signal
104 Palpitations 75 5.9 6.1 signal
105 Hypertension 135 5.9 6.2 signal
106 Arteriosclerosis 6 5.9 5.9 signal
107 Vomiting 295 5.8 6.6 signal
108 Psoriasis 82 5.8 6.0 signal
109 Blood Pressure Systolic Increased 12 5.7 5.7 signal
110 Proteinuria 11 5.4 5.4 signal
111 Dyspnoea 325 5.3 6.1 signal
112 Disease Progression 67 5.3 5.4 signal
113 Anxiety 159 5.2 5.5 signal
114 Pruritus 204 5.0 5.4 signal
115 Atrial Fibrillation 52 4.9 5.0 signal
116 Face Oedema 9 4.9 4.9 signal
117 Rebound Effect 6 4.9 4.9 signal
118 Dizziness 262 4.9 5.4 signal
119 Headache 320 4.7 5.4 signal
120 Metabolic Acidosis 16 4.7 4.7 signal
121 Arthralgia 208 4.7 5.0 signal
122 Haematoma 13 4.6 4.7 signal
123 Toxic Skin Eruption 5 4.6 4.6 signal
124 Pulmonary Oedema 22 4.6 4.6 signal
125 Nasopharyngitis 88 4.4 4.6 signal
126 Circulatory Collapse 8 4.3 4.4 signal
127 Contraindicated Product Administered 14 4.3 4.3 signal
128 Nephropathy 4 4.0 4.0 signal
129 Posterior Reversible Encephalopathy Syndrome 4 3.9 3.9 signal
130 Cardiac Failure Congestive 34 3.9 3.9 signal
131 Upper Gastrointestinal Haemorrhage 7 3.8 3.9 signal
132 Sinus Bradycardia 4 3.8 3.8 signal
133 Melaena 9 3.8 3.8 signal
134 Colon Cancer 6 3.7 3.7 signal
135 Product Use Issue 75 3.7 3.8 signal
136 Ischaemic Stroke 7 3.6 3.6 signal
137 Electrocardiogram Qt Prolonged 14 3.6 3.6 signal
138 Hypoglycaemia 18 3.4 3.5 signal
139 Coronary Artery Occlusion 5 3.4 3.4 signal
140 Fluid Overload 5 3.1 3.1 signal
141 Exposure During Pregnancy 20 3.0 3.0 signal
142 Grand Mal Convulsion 3 3.0 3.0 no signal
143 Maternal Exposure During Pregnancy 23 2.4 2.4 signal
144 Gastric Cancer 5 1.8 1.8 no signal
145 Pancreatic Carcinoma 3 1.0 1.0 no signal
146 Prostate Cancer 8 0.9 0.9 no signal
147 Bladder Cancer 3 0.5 0.5 no signal