OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Allantoin

308 flagged reaction(s) · 10,016 total co-reports · max PRR 85.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Appendicitis 123 85.5 88.8 signal
2 Ventricular Fibrillation 129 74.7 77.8 signal
3 Cardiogenic Shock 119 53.6 55.6 signal
4 Bacterial Infection 108 37.3 38.5 signal
5 Incorrect Route Of Product Administration 89 34.0 34.9 signal
6 Hyperlipidaemia 61 32.6 33.2 signal
7 Multiple Organ Dysfunction Syndrome 135 31.0 32.3 signal
8 Ascites 134 29.2 30.4 signal
9 Neuralgia 110 29.1 30.0 signal
10 Ulcer 62 24.9 25.4 signal
11 Aspiration 40 23.6 23.9 signal
12 Gout 65 23.2 23.6 signal
13 Blood Test Abnormal 49 22.3 22.7 signal
14 Hypercholesterolaemia 30 20.1 20.2 signal
15 Pharmaceutical Product Complaint 82 19.9 20.4 signal
16 End Stage Renal Disease 57 19.8 20.1 signal
17 Full Blood Count Abnormal 30 18.2 18.4 signal
18 Hyponatraemia 159 18.1 19.0 signal
19 Drug Toxicity 39 18.1 18.3 signal
20 Anorexia 35 17.1 17.3 signal
21 Micturition Urgency 29 16.4 16.5 signal
22 Chronic Obstructive Pulmonary Disease 120 14.7 15.2 signal
23 Blood Cholesterol Increased 105 14.4 14.8 signal
24 Stress 146 13.0 13.5 signal
25 Dry Mouth 142 11.2 11.7 signal
26 Economic Problem 27 11.2 11.3 signal
27 Diabetes Mellitus 128 10.7 11.1 signal
28 Transaminases Increased 37 10.6 10.8 signal
29 Coronary Artery Disease 49 10.3 10.4 signal
30 Sleep Disorder 109 10.0 10.3 signal
31 Sepsis 168 9.6 10.1 signal
32 Mitral Valve Incompetence 17 9.6 9.6 signal
33 Joint Injury 32 9.6 9.6 signal
34 Thrombosis 119 9.4 9.7 signal
35 Abdominal Distension 153 9.4 9.8 signal
36 Iron Deficiency Anaemia 13 9.0 9.1 signal
37 Cardiovascular Disorder 36 9.0 9.1 signal
38 Sputum Discoloured 13 8.8 8.8 signal
39 Renal Failure Acute 58 8.6 8.7 signal
40 General Physical Health Deterioration 154 8.6 8.9 signal
41 Pulmonary Embolism 124 8.3 8.6 signal
42 Blood Creatinine Increased 84 8.2 8.4 signal
43 Grand Mal Convulsion 12 8.2 8.2 signal
44 Dialysis 18 8.1 8.1 signal
45 Drug Intolerance 118 7.8 8.1 signal
46 Swelling 114 7.8 8.0 signal
47 Lower Respiratory Tract Infection 55 7.8 7.9 signal
48 Convulsion 69 7.6 7.7 signal
49 International Normalised Ratio Increased 34 7.5 7.6 signal
50 Transient Ischaemic Attack 40 7.5 7.6 signal
51 Obstructive Airways Disorder 13 7.4 7.5 signal
52 Intentional Product Misuse 101 7.4 7.6 signal
53 Breast Cancer Female 31 7.4 7.4 signal
54 Mental Status Changes 32 7.4 7.4 signal
55 Aspartate Aminotransferase Increased 61 7.3 7.5 signal
56 Blood Urea Increased 19 7.2 7.2 signal
57 Cardiomegaly 14 7.2 7.2 signal
58 Pleural Effusion 66 6.9 7.0 signal
59 Atelectasis 10 6.6 6.6 signal
60 Pulmonary Mass 15 6.4 6.5 signal
61 Pulmonary Fibrosis 19 6.3 6.4 signal
62 Blood Glucose Decreased 47 6.2 6.3 signal
63 Somnolence 196 6.2 6.6 signal
64 Oedema Peripheral 119 6.2 6.4 signal
65 Anosmia 14 6.2 6.2 signal
66 Haematocrit Decreased 19 6.1 6.1 signal
67 Liver Function Test Increased 20 6.0 6.0 signal
68 Caesarean Section 11 6.0 6.0 signal
69 Anaemia 175 5.9 6.1 signal
70 Renal Tubular Necrosis 9 5.8 5.9 signal
71 Multi-organ Failure 16 5.8 5.8 signal
72 Ventricular Tachycardia 15 5.8 5.8 signal
73 Drug Exposure During Pregnancy 31 5.7 5.8 signal
74 Abdominal Pain 207 5.7 6.0 signal
75 Post Procedural Complication 17 5.6 5.7 signal
76 Hyperbilirubinaemia 9 5.6 5.6 signal
77 Upper Respiratory Tract Infection 40 5.5 5.6 signal
78 Haemoptysis 24 5.5 5.5 signal
79 Sinus Tachycardia 12 5.4 5.4 signal
80 Sudden Death 9 5.4 5.4 signal
81 Pregnancy 17 5.4 5.4 signal
82 Sinus Bradycardia 8 5.3 5.3 signal
83 Cardiomyopathy 12 5.2 5.2 signal
84 No Therapeutic Response 10 5.2 5.2 signal
85 Condition Aggravated 239 5.1 5.4 signal
86 Liver Disorder 35 5.0 5.1 signal
87 Liver Function Test Abnormal 23 5.0 5.0 signal
88 Constipation 169 5.0 5.2 signal
89 Hypoxia 27 4.9 4.9 signal
90 Ventricular Extrasystoles 8 4.9 4.9 signal
91 Drug Effect Decreased 42 4.9 5.0 signal
92 Blood Glucose Increased 144 4.9 5.0 signal
93 Medication Error 42 4.8 4.9 signal
94 Rhabdomyolysis 31 4.8 4.8 signal
95 Musculoskeletal Stiffness 65 4.7 4.8 signal
96 Blood Glucose Fluctuation 8 4.6 4.7 signal
97 Disseminated Intravascular Coagulation 10 4.5 4.5 signal
98 Ejection Fraction Decreased 11 4.5 4.5 signal
99 Electrolyte Imbalance 8 4.4 4.4 signal
100 Lung Disorder 34 4.4 4.5 signal
101 Emphysema 7 4.4 4.4 signal
102 Sedation 18 4.4 4.4 signal
103 Blood Lactate Dehydrogenase Increased 11 4.4 4.4 signal
104 Hyperkalaemia 24 4.4 4.4 signal
105 Blood Creatine Phosphokinase Increased 20 4.4 4.4 signal
106 Eructation 13 4.4 4.4 signal
107 Blood Alkaline Phosphatase Increased 17 4.4 4.4 signal
108 Hypoglycaemia 33 4.3 4.4 signal
109 Abasia 17 4.3 4.3 signal
110 Diabetes Mellitus Inadequate Control 12 4.3 4.3 signal
111 Pulmonary Hypertension 14 4.3 4.3 signal
112 Drug Hypersensitivity 130 4.3 4.4 signal
113 Muscle Rigidity 8 4.3 4.3 signal
114 Osteomyelitis 12 4.2 4.2 signal
115 Coagulopathy 11 4.2 4.2 signal
116 Psychomotor Hyperactivity 11 4.2 4.2 signal
117 Respiratory Distress 18 4.2 4.2 signal
118 Skin Laceration 7 4.1 4.1 signal
119 Scar 11 4.1 4.1 signal
120 Coordination Abnormal 9 4.1 4.1 signal
121 Thinking Abnormal 12 4.1 4.1 signal
122 Weight Decreased 177 4.0 4.2 signal
123 Blood Potassium Decreased 19 4.0 4.0 signal
124 Mydriasis 8 4.0 4.0 signal
125 Alanine Aminotransferase Increased 38 3.9 4.0 signal
126 Vomiting 289 3.9 4.2 signal
127 Motor Dysfunction 6 3.8 3.8 signal
128 Tachypnoea 8 3.8 3.8 signal
129 Fear 16 3.8 3.8 signal
130 Tremor 98 3.8 3.8 signal
131 Circulatory Collapse 10 3.7 3.7 signal
132 Bradycardia 31 3.7 3.7 signal
133 Haematuria 20 3.7 3.7 signal
134 Erectile Dysfunction 15 3.7 3.7 signal
135 Euphoric Mood 6 3.7 3.7 signal
136 Cholestasis 11 3.7 3.7 signal
137 Lethargy 33 3.7 3.7 signal
138 Cyanosis 9 3.6 3.7 signal
139 Ileus 7 3.6 3.6 signal
140 Subdural Haematoma 8 3.6 3.6 signal
141 Blood Bilirubin Increased 15 3.5 3.5 signal
142 Gastroenteritis 8 3.5 3.5 signal
143 Pruritus Generalised 12 3.5 3.5 signal
144 Dehydration 72 3.4 3.5 signal
145 Respiratory Arrest 15 3.4 3.5 signal
146 Disorientation 21 3.4 3.4 signal
147 Abnormal Behaviour 21 3.4 3.4 signal
148 Feeling Jittery 10 3.3 3.3 signal
149 Hyperglycaemia 19 3.3 3.4 signal
150 Atrial Fibrillation 51 3.3 3.4 signal
151 Nausea 410 3.3 3.6 signal
152 Nervous System Disorder 16 3.3 3.3 signal
153 Cold Sweat 9 3.3 3.3 signal
154 Depressed Level Of Consciousness 20 3.2 3.2 signal
155 Cerebral Haemorrhage 18 3.2 3.2 signal
156 Cardio-respiratory Arrest 21 3.2 3.2 signal
157 Hypotonia 5 3.2 3.2 signal
158 Gastrointestinal Disorder 44 3.2 3.2 signal
159 Crying 18 3.1 3.2 signal
160 Pancreatitis Acute 11 3.1 3.2 signal
161 Initial Insomnia 5 3.1 3.1 signal
162 Subarachnoid Haemorrhage 5 3.1 3.1 signal
163 Bronchospasm 7 3.1 3.1 signal
164 Shock 11 3.1 3.1 signal
165 Petechiae 5 3.1 3.1 signal
166 Ageusia 12 3.1 3.1 signal
167 Treatment Noncompliance 26 3.1 3.1 signal
168 Multiple Sclerosis 23 3.1 3.1 signal
169 Fluid Overload 7 3.0 3.0 signal
170 Cardiac Failure Congestive 38 3.0 3.0 signal
171 Dyskinesia 19 3.0 3.0 signal
172 Decreased Activity 5 3.0 3.0 signal
173 Restlessness 17 3.0 3.0 signal
174 Device Failure 7 2.9 2.9 signal
175 Haematoma 12 2.9 3.0 signal
176 Haemoglobin Decreased 47 2.9 2.9 signal
177 Immune System Disorder 6 2.9 2.9 signal
178 Osteonecrosis 15 2.9 2.9 signal
179 Loss Of Consciousness 58 2.9 2.9 signal
180 Hyperhidrosis 58 2.9 2.9 signal
181 Pharyngeal Oedema 7 2.9 2.9 signal
182 Influenza Like Illness 37 2.9 2.9 signal
183 Hunger 6 2.8 2.9 signal
184 Jaundice 12 2.8 2.8 signal
185 Status Epilepticus 5 2.8 2.8 signal
186 Flatulence 25 2.8 2.8 signal
187 Coma 21 2.8 2.8 signal
188 Gingival Bleeding 6 2.8 2.8 signal
189 Myocardial Ischaemia 5 2.8 2.8 signal
190 Pancreatitis 23 2.8 2.8 signal
191 Sensory Disturbance 7 2.8 2.8 signal
192 Hepatitis 11 2.7 2.7 signal
193 Erythema Multiforme 4 2.7 2.7 no signal
194 Post Procedural Haemorrhage 5 2.7 2.7 no signal
195 Personality Change 4 2.7 2.7 no signal
196 Increased Appetite 8 2.7 2.7 signal
197 Febrile Neutropenia 28 2.7 2.7 signal
198 Impaired Work Ability 9 2.7 2.7 signal
199 Asthma 47 2.7 2.7 signal
200 Nervousness 22 2.7 2.7 signal
201 Rash Generalised 11 2.7 2.7 signal
202 Angina Pectoris 12 2.7 2.7 signal
203 Hyperthyroidism 6 2.6 2.6 signal
204 Anger 14 2.6 2.6 signal
205 Hemiparesis 7 2.6 2.6 signal
206 Cerebral Infarction 10 2.6 2.6 signal
207 Melaena 9 2.6 2.6 signal
208 Agitation 30 2.6 2.6 signal
209 Disturbance In Attention 22 2.6 2.6 signal
210 Hepatic Function Abnormal 15 2.6 2.6 signal
211 Paranoia 7 2.6 2.6 signal
212 Metastases To Liver 7 2.5 2.6 signal
213 Hepatic Failure 12 2.5 2.5 signal
214 Heart Rate Irregular 9 2.5 2.5 signal
215 Toxic Skin Eruption 4 2.5 2.5 no signal
216 Hypothermia 4 2.5 2.5 no signal
217 Suicidal Ideation 36 2.5 2.5 signal
218 Visual Acuity Reduced 13 2.5 2.5 signal
219 Drug Dispensing Error 6 2.5 2.5 no signal
220 Lymphoma 6 2.5 2.5 no signal
221 Tendonitis 6 2.5 2.5 no signal
222 Mucosal Inflammation 10 2.4 2.5 signal
223 Anaphylactic Reaction 21 2.4 2.4 signal
224 Irritability 23 2.4 2.4 signal
225 Lung Infection 6 2.4 2.4 no signal
226 Aggression 19 2.4 2.4 signal
227 Drug Withdrawal Syndrome 33 2.4 2.4 signal
228 Localised Infection 9 2.4 2.4 signal
229 Mental Impairment 9 2.4 2.4 signal
230 Akathisia 5 2.3 2.3 no signal
231 Serotonin Syndrome 7 2.3 2.3 signal
232 Bipolar Disorder 4 2.3 2.3 no signal
233 Gastrointestinal Pain 4 2.3 2.3 no signal
234 Mania 6 2.3 2.3 no signal
235 Coronary Artery Occlusion 5 2.3 2.3 no signal
236 Prescribed Overdose 7 2.3 2.3 no signal
237 Cytomegalovirus Infection 6 2.3 2.3 no signal
238 Nephropathy Toxic 4 2.3 2.3 no signal
239 Blindness Unilateral 5 2.3 2.3 no signal
240 Emotional Disorder 11 2.3 2.3 signal
241 Activities Of Daily Living Impaired 7 2.2 2.2 no signal
242 Dysgeusia 26 2.2 2.2 signal
243 Gastric Haemorrhage 4 2.2 2.2 no signal
244 Mood Swings 11 2.2 2.2 signal
245 Disease Progression 40 2.2 2.2 signal
246 Psychotic Disorder 10 2.2 2.2 signal
247 Hallucination, Visual 7 2.1 2.1 no signal
248 Haemorrhage Intracranial 5 2.1 2.1 no signal
249 Multiple Sclerosis Relapse 23 2.1 2.1 signal
250 Toxic Epidermal Necrolysis 5 2.1 2.1 no signal
251 Pelvic Pain 6 2.1 2.1 no signal
252 Respiratory Depression 4 2.1 2.1 no signal
253 Agranulocytosis 6 2.1 2.1 no signal
254 Ovarian Cancer 3 2.1 2.1 no signal
255 Libido Decreased 4 2.1 2.1 no signal
256 Drug Administration Error 10 2.0 2.1 signal
257 Glycosylated Haemoglobin Increased 8 2.0 2.0 no signal
258 Injection Site Irritation 4 2.0 2.0 no signal
259 Disease Recurrence 15 2.0 2.0 signal
260 Tuberculosis 4 2.0 2.0 no signal
261 Thrombotic Microangiopathy 3 2.0 2.0 no signal
262 Drug Level Increased 5 1.9 1.9 no signal
263 Eye Haemorrhage 4 1.9 1.9 no signal
264 Inappropriate Antidiuretic Hormone Secretion 3 1.9 1.9 no signal
265 Knee Arthroplasty 6 1.8 1.8 no signal
266 Local Swelling 5 1.8 1.8 no signal
267 Lactic Acidosis 9 1.8 1.8 no signal
268 Myelodysplastic Syndrome 4 1.8 1.8 no signal
269 Apathy 4 1.8 1.8 no signal
270 Accidental Overdose 10 1.7 1.7 no signal
271 Injection Site Bruising 21 1.7 1.7 no signal
272 Impaired Driving Ability 3 1.7 1.7 no signal
273 Delusion 4 1.6 1.6 no signal
274 Sexual Dysfunction 3 1.6 1.6 no signal
275 Acute Myeloid Leukaemia 4 1.6 1.6 no signal
276 Dystonia 5 1.6 1.6 no signal
277 Neuroleptic Malignant Syndrome 3 1.6 1.6 no signal
278 Injection Site Haemorrhage 20 1.6 1.6 no signal
279 Abnormal Dreams 7 1.6 1.6 no signal
280 Myocardial Infarction 44 1.6 1.6 no signal
281 Schizophrenia 3 1.6 1.6 no signal
282 Bone Marrow Failure 5 1.6 1.6 no signal
283 Product Substitution Issue 14 1.6 1.6 no signal
284 Injection Site Discolouration 3 1.5 1.5 no signal
285 Muscle Spasticity 3 1.5 1.5 no signal
286 Injection Site Extravasation 3 1.5 1.5 no signal
287 Amenorrhoea 4 1.5 1.5 no signal
288 Completed Suicide 20 1.5 1.5 no signal
289 Metastases To Central Nervous System 3 1.5 1.5 no signal
290 Injection Site Rash 7 1.5 1.5 no signal
291 Application Site Rash 3 1.4 1.4 no signal
292 Wrong Technique In Drug Usage Process 8 1.4 1.4 no signal
293 Malignant Neoplasm Progression 21 1.3 1.3 no signal
294 Drug Prescribing Error 4 1.3 1.3 no signal
295 Menorrhagia 4 1.3 1.3 no signal
296 Abortion Spontaneous 8 1.3 1.3 no signal
297 Lung Neoplasm Malignant 8 1.2 1.2 no signal
298 Application Site Erythema 5 1.2 1.2 no signal
299 Tardive Dyskinesia 5 1.1 1.1 no signal
300 Breast Cancer 16 1.1 1.1 no signal
301 Synovitis 3 1.1 1.1 no signal
302 Menstruation Irregular 4 1.0 1.0 no signal
303 Application Site Pain 3 0.9 0.9 no signal
304 Injection Site Erythema 15 0.8 0.8 no signal
305 Intentional Overdose 7 0.7 0.7 no signal
306 Injection Site Pruritus 7 0.7 0.7 no signal
307 Drug Dependence 10 0.4 0.4 no signal
308 Bladder Cancer 3 0.3 0.3 no signal