Drug

Asciminib

85 flagged reaction(s) · 2,158 total co-reports · max PRR 47.9

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Cytopenia	86	47.9	49.2	signal
2	Haematotoxicity	24	17.1	17.3	signal
3	Pericardial Effusion	59	17.0	17.3	signal
4	Drug Resistance	49	12.6	12.8	signal
5	Hepatotoxicity	38	11.3	11.5	signal
6	Leukaemia	16	11.2	11.3	signal
7	Pleural Effusion	99	10.8	11.1	signal
8	Thrombocytopenia	158	9.4	9.8	signal
9	Leukocytosis	25	9.1	9.2	signal
10	Pancreatitis	72	9.0	9.2	signal
11	Drug Intolerance	128	8.8	9.1	signal
12	Splenomegaly	14	7.9	7.9	signal
13	Platelet Count Increased	15	7.6	7.6	signal
14	Pulmonary Hypertension	24	7.6	7.6	signal
15	Pancytopenia	61	7.2	7.4	signal
16	Pericarditis	18	7.1	7.2	signal
17	Arteriosclerosis	10	7.0	7.0	signal
18	Posterior Reversible Encephalopathy Syndrome	10	6.9	7.0	signal
19	Full Blood Count Decreased	20	6.6	6.6	signal
20	Brain Fog	14	6.3	6.4	signal
21	Bone Pain	55	6.2	6.3	signal
22	Supraventricular Tachycardia	8	5.5	5.5	signal
23	Malignant Neoplasm Progression	85	5.5	5.6	signal
24	Electrocardiogram Qt Prolonged	29	5.3	5.4	signal
25	Platelet Count Decreased	81	5.0	5.1	signal
26	Nephropathy	7	4.9	4.9	signal
27	Cerebral Infarction	18	4.9	4.9	signal
28	Bone Marrow Failure	15	4.8	4.9	signal
29	White Blood Cell Count Increased	27	4.6	4.7	signal
30	Transaminases Increased	15	4.5	4.5	signal
31	Treatment Failure	54	4.3	4.4	signal
32	Nephropathy Toxic	7	4.2	4.2	signal
33	Blood Bilirubin Increased	17	4.1	4.2	signal
34	Acute Myocardial Infarction	18	4.0	4.0	signal
35	Ventricular Tachycardia	10	4.0	4.0	signal
36	Malignant Melanoma	8	3.9	3.9	signal
37	Hepatic Cytolysis	7	3.8	3.8	signal
38	Musculoskeletal Pain	30	3.8	3.8	signal
39	Renal Impairment	47	3.7	3.8	signal
40	Dermatitis Allergic	7	3.7	3.7	signal
41	Transient Ischaemic Attack	19	3.7	3.7	signal
42	Myelodysplastic Syndrome	8	3.7	3.7	signal
43	Neutrophil Count Decreased	22	3.6	3.6	signal
44	Therapy Non-responder	24	3.6	3.6	signal
45	Hypertensive Crisis	6	3.6	3.6	signal
46	Therapeutic Response Decreased	31	3.4	3.4	signal
47	Myalgia	80	3.1	3.2	signal
48	Neutropenia	62	3.0	3.1	signal
49	Obstructive Airways Disorder	5	3.0	3.0	signal
50	Leukopenia	21	2.8	2.8	signal
51	Polyneuropathy	5	2.8	2.8	signal
52	Myelosuppression	14	2.7	2.7	signal
53	Decreased Immune Responsiveness	4	2.7	2.7	no signal
54	Neurotoxicity	7	2.7	2.7	signal
55	Tooth Disorder	9	2.7	2.7	signal
56	Product Administration Error	8	2.6	2.7	signal
57	Dementia	11	2.6	2.6	signal
58	Sudden Death	4	2.5	2.5	no signal
59	Laboratory Test Abnormal	11	2.5	2.5	signal
60	Ocular Discomfort	4	2.4	2.4	no signal
61	Nerve Injury	4	2.4	2.4	no signal
62	Cardiovascular Disorder	9	2.3	2.3	signal
63	Therapy Interrupted	24	2.3	2.3	signal
64	Pulmonary Arterial Hypertension	5	2.3	2.3	no signal
65	Hospitalisation	52	2.3	2.3	signal
66	Cerebrovascular Accident	58	2.3	2.3	signal
67	Cholestasis	6	2.1	2.1	no signal
68	Cardiac Disorder	29	2.0	2.0	signal
69	Neoplasm Malignant	19	1.9	1.9	no signal
70	Ischaemic Stroke	5	1.8	1.8	no signal
71	Myocarditis	3	1.8	1.8	no signal
72	Gastric Haemorrhage	3	1.7	1.7	no signal
73	Myocardial Infarction	44	1.7	1.7	no signal
74	Muscle Spasticity	3	1.6	1.6	no signal
75	Peritonitis	5	1.6	1.6	no signal
76	Product Availability Issue	5	1.5	1.5	no signal
77	Cytokine Release Syndrome	4	1.4	1.4	no signal
78	Gynaecomastia	6	1.3	1.3	no signal
79	Product Dispensing Error	4	1.2	1.2	no signal
80	Product Storage Error	12	0.9	0.9	no signal
81	Renal Cancer	6	0.8	0.8	no signal
82	Gastric Cancer	3	0.8	0.8	no signal
83	Tardive Dyskinesia	3	0.7	0.7	no signal
84	Product Adhesion Issue	3	0.6	0.6	no signal
85	Bladder Cancer	3	0.3	0.3	no signal