Drug

Butalbital And Acetaminophen

45 flagged reaction(s) · 450 total co-reports · max PRR 54.7

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Helicobacter Infection	16	54.7	56.2	signal
2	Folliculitis	16	54.0	55.5	signal
3	Sciatica	17	37.4	38.4	signal
4	Hand Deformity	14	37.3	38.2	signal
5	Wound Infection	11	35.3	35.9	signal
6	Pemphigus	12	33.6	34.3	signal
7	Synovitis	15	29.0	29.7	signal
8	Bursitis	10	28.9	29.4	signal
9	Pericarditis	13	27.2	27.8	signal
10	Irritable Bowel Syndrome	16	26.1	26.8	signal
11	Joint Range Of Motion Decreased	10	26.1	26.5	signal
12	Fibromyalgia	18	25.8	26.6	signal
13	Autoimmune Disorder	7	25.5	25.8	signal
14	Foot Deformity	7	22.0	22.2	signal
15	Glossodynia	14	21.8	22.3	signal
16	Wound	16	20.1	20.6	signal
17	Prescribed Overdose	11	19.8	20.2	signal
18	Infusion Site Pain	7	19.1	19.3	signal
19	Systemic Lupus Erythematosus	18	17.7	18.2	signal
20	Sleep Disorder Due To A General Medical Condition	8	17.2	17.5	signal
21	Lower Limb Fracture	9	16.4	16.7	signal
22	Hip Arthroplasty	7	16.1	16.2	signal
23	Impaired Healing	15	15.9	16.3	signal
24	Type 2 Diabetes Mellitus	15	15.5	15.8	signal
25	Psoriatic Arthropathy	17	14.7	15.1	signal
26	Road Traffic Accident	17	14.2	14.5	signal
27	Disability	8	14.1	14.3	signal
28	Pregnancy	8	13.8	14.0	signal
29	Pharyngitis Streptococcal	4	12.9	13.0	signal
30	Red Blood Cell Sedimentation Rate Increased	4	12.6	12.6	signal
31	Impaired Quality Of Life	5	12.1	12.2	signal
32	Neoplasm	4	12.1	12.2	signal
33	Metastases To Lung	4	12.1	12.1	signal
34	Therapeutic Product Effect Decreased	15	11.8	12.1	signal
35	Poisoning	4	11.0	11.1	signal
36	Coeliac Disease	3	10.6	10.7	signal
37	Prescribed Underdose	6	10.5	10.6	signal
38	Muscle Spasticity	3	8.4	8.5	signal
39	Ankylosing Spondylitis	3	8.0	8.1	signal
40	Bone Density Decreased	5	5.5	5.5	signal
41	Completed Suicide	12	5.0	5.0	signal
42	Injection Site Bruising	11	4.9	4.9	signal
43	Multiple Sclerosis Relapse	9	4.5	4.6	signal
44	Injection Site Urticaria	3	4.3	4.3	signal
45	Device Difficult To Use	3	1.6	1.6	no signal