OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Caffeine

515 flagged reaction(s) · 110,344 total co-reports · max PRR 276.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Helicobacter Infection 948 276.1 314.1 signal
2 Folliculitis 878 250.1 281.7 signal
3 Pemphigus 960 225.3 256.8 signal
4 Autoimmune Disorder 711 216.0 237.6 signal
5 Hand Deformity 963 213.9 243.9 signal
6 Pericarditis 963 165.1 188.2 signal
7 Bursitis 600 140.8 152.5 signal
8 Synovitis 880 137.9 155.4 signal
9 Glossodynia 909 114.0 129.0 signal
10 Joint Range Of Motion Decreased 536 112.4 120.6 signal
11 Sciatica 602 106.2 115.0 signal
12 Irritable Bowel Syndrome 786 102.8 114.2 signal
13 Lower Limb Fracture 678 99.0 108.4 signal
14 Fibromyalgia 848 97.3 109.1 signal
15 Liver Injury 786 90.4 100.4 signal
16 Wound Infection 337 86.1 89.9 signal
17 Hypercholesterolaemia 290 84.1 87.3 signal
18 Wound 823 82.1 91.6 signal
19 Obesity 430 74.5 78.8 signal
20 Systemic Lupus Erythematosus 888 69.3 78.0 signal
21 Prescribed Overdose 474 67.5 71.9 signal
22 Impaired Healing 800 67.2 74.7 signal
23 Type 2 Diabetes Mellitus 809 66.0 73.5 signal
24 Pulmonary Fibrosis 447 64.4 68.3 signal
25 Psoriatic Arthropathy 834 57.0 63.7 signal
26 Contraindicated Product Administered 616 56.1 60.8 signal
27 Laryngitis 214 54.1 55.6 signal
28 Foot Deformity 212 52.4 53.8 signal
29 Blood Cholesterol Increased 890 52.3 58.9 signal
30 Lower Respiratory Tract Infection 863 52.2 58.6 signal
31 Hip Arthroplasty 276 49.8 51.6 signal
32 Gait Inability 595 49.2 53.2 signal
33 Arthropathy 997 49.0 56.0 signal
34 Night Sweats 571 48.6 52.3 signal
35 Road Traffic Accident 683 44.6 48.8 signal
36 Osteoarthritis 678 43.6 47.7 signal
37 Blister 894 43.6 49.1 signal
38 Pregnancy 322 43.5 45.3 signal
39 Stomatitis 933 42.0 47.6 signal
40 Discomfort 917 41.3 46.7 signal
41 Oedema 809 40.8 45.4 signal
42 Infusion Related Reaction 973 40.2 45.8 signal
43 Hepatic Enzyme Increased 979 39.3 44.8 signal
44 Red Blood Cell Sedimentation Rate Increased 150 36.9 37.6 signal
45 Liver Disorder 595 36.6 39.6 signal
46 Mobility Decreased 951 36.2 41.1 signal
47 Hepatic Cirrhosis 244 35.6 36.7 signal
48 Joint Dislocation 136 35.2 35.8 signal
49 Prescribed Underdose 253 34.6 35.7 signal
50 Therapy Non-responder 551 33.7 36.1 signal
51 Therapeutic Product Effect Decreased 547 33.6 36.0 signal
52 Knee Arthroplasty 252 32.9 34.0 signal
53 Lung Disorder 588 32.7 35.3 signal
54 Wheezing 694 31.9 35.0 signal
55 Injury 807 31.1 34.5 signal
56 Musculoskeletal Pain 575 29.6 31.9 signal
57 Delirium 356 28.0 29.3 signal
58 Swelling 916 26.6 30.1 signal
59 Maternal Exposure During Pregnancy 864 26.6 29.8 signal
60 Musculoskeletal Stiffness 847 26.2 29.3 signal
61 Incorrect Route Of Product Administration 162 26.2 26.7 signal
62 Sleep Disorder Due To A General Medical Condition 154 25.9 26.4 signal
63 Ill-defined Disorder 564 25.2 27.1 signal
64 Drug Intolerance 868 24.5 27.4 signal
65 Ear Pain 175 24.4 25.0 signal
66 Gastrointestinal Disorder 775 23.8 26.3 signal
67 Respiratory Disorder 256 23.1 23.9 signal
68 Sleep Disorder 597 23.1 25.0 signal
69 Treatment Failure 699 23.1 25.3 signal
70 Blood Calcium Decreased 96 23.1 23.4 signal
71 Rheumatoid Arthritis 938 22.5 25.4 signal
72 Sinusitis 845 22.3 24.9 signal
73 Contusion 790 22.3 24.7 signal
74 Toxicity To Various Agents 1,374 22.2 26.7 signal
75 Inflammation 411 21.7 22.9 signal
76 Dry Mouth 641 21.5 23.3 signal
77 Ear Infection 209 21.3 21.9 signal
78 Joint Swelling 946 21.3 24.1 signal
79 General Physical Health Deterioration 878 20.7 23.2 signal
80 Weight Fluctuation 74 19.2 19.4 signal
81 Disability 140 19.2 19.5 signal
82 Asthma 779 18.8 20.8 signal
83 Joint Stiffness 174 18.0 18.3 signal
84 C-reactive Protein Increased 238 17.7 18.2 signal
85 Abdominal Discomfort 1,050 17.0 19.5 signal
86 Back Injury 68 17.0 17.1 signal
87 Frequent Bowel Movements 168 16.9 17.2 signal
88 Exposure During Pregnancy 385 16.8 17.6 signal
89 Confusional State 984 16.4 18.7 signal
90 Intentional Product Use Issue 525 16.2 17.2 signal
91 Drug Abuse 483 15.6 16.6 signal
92 Brain Oedema 72 15.4 15.6 signal
93 Liver Function Test Increased 121 15.3 15.6 signal
94 Urticaria 944 15.3 17.3 signal
95 Migraine 532 15.2 16.2 signal
96 Amnesia 362 15.0 15.7 signal
97 Alopecia 1,079 14.8 17.1 signal
98 Orthostatic Hypotension 93 14.4 14.6 signal
99 Peripheral Swelling 808 14.2 15.8 signal
100 Hypoaesthesia 758 13.7 15.0 signal
101 Nasopharyngitis 931 13.6 15.3 signal
102 Infection 724 13.6 14.9 signal
103 Hypersensitivity 910 13.3 14.9 signal
104 Sedation 127 13.2 13.4 signal
105 Muscle Spasticity 60 13.1 13.2 signal
106 Osteoporosis 198 13.0 13.3 signal
107 Laboratory Test Abnormal 141 12.9 13.1 signal
108 Dyspepsia 459 12.6 13.4 signal
109 Drug Hypersensitivity 888 12.4 13.8 signal
110 Abdominal Pain Upper 925 12.2 13.7 signal
111 Chest Pain 802 11.7 12.9 signal
112 Emphysema 43 11.5 11.5 signal
113 Colitis Ulcerative 185 11.2 11.5 signal
114 Rectal Haemorrhage 176 11.0 11.3 signal
115 Hypertension 855 10.9 12.1 signal
116 White Blood Cell Count Increased 155 10.9 11.1 signal
117 Completed Suicide 337 10.8 11.3 signal
118 Medication Error 222 10.8 11.1 signal
119 Pulmonary Congestion 52 10.6 10.7 signal
120 Weight Increased 871 10.6 11.8 signal
121 Brain Injury 39 10.5 10.5 signal
122 Depressed Level Of Consciousness 151 10.3 10.5 signal
123 Adverse Event 339 9.9 10.3 signal
124 Oedema Peripheral 430 9.5 10.0 signal
125 Pancreatitis 184 9.4 9.6 signal
126 Condition Aggravated 1,047 9.4 10.7 signal
127 Sleep Apnoea Syndrome 65 9.2 9.2 signal
128 Serotonin Syndrome 65 9.2 9.2 signal
129 Taste Disorder 68 9.2 9.2 signal
130 Decreased Appetite 754 8.8 9.6 signal
131 Adverse Drug Reaction 290 8.7 9.0 signal
132 Intentional Overdose 205 8.7 8.9 signal
133 Tuberculosis 41 8.6 8.6 signal
134 Muscular Weakness 359 8.5 8.9 signal
135 Paraesthesia 495 8.5 9.0 signal
136 Memory Impairment 431 8.5 8.9 signal
137 Cognitive Disorder 144 8.4 8.5 signal
138 Product Use Issue 577 8.3 8.9 signal
139 Feeling Hot 189 8.3 8.5 signal
140 Mydriasis 39 8.2 8.2 signal
141 Loss Of Personal Independence In Daily Activities 142 8.1 8.2 signal
142 Therapeutic Response Decreased 179 8.0 8.2 signal
143 Sinus Tachycardia 42 8.0 8.0 signal
144 Respiratory Depression 36 7.9 8.0 signal
145 Body Temperature Increased 60 7.9 8.0 signal
146 Anxiety 834 7.9 8.7 signal
147 Arthritis 229 7.8 8.0 signal
148 Drug Toxicity 40 7.8 7.8 signal
149 Epilepsy 87 7.7 7.8 signal
150 Muscle Spasms 520 7.6 8.1 signal
151 Drug-induced Liver Injury 87 7.6 7.7 signal
152 Dermatitis Allergic 35 7.6 7.6 signal
153 Circulatory Collapse 48 7.6 7.6 signal
154 Insomnia 740 7.5 8.2 signal
155 Arteriosclerosis 26 7.4 7.5 signal
156 Pyrexia 923 7.2 8.0 signal
157 Gait Disturbance 511 7.2 7.6 signal
158 Arthralgia 1,094 7.1 8.1 signal
159 Bladder Disorder 26 7.0 7.1 signal
160 Adrenal Insufficiency 31 7.0 7.0 signal
161 Coeliac Disease 25 6.9 6.9 signal
162 Pulmonary Oedema 114 6.9 6.9 signal
163 Metabolic Acidosis 80 6.8 6.9 signal
164 Cardio-respiratory Arrest 106 6.8 6.9 signal
165 Overdose 538 6.7 7.1 signal
166 Cystitis 79 6.7 6.7 signal
167 Drug Interaction 391 6.6 6.9 signal
168 Unresponsive To Stimuli 63 6.6 6.6 signal
169 Respiratory Arrest 67 6.5 6.5 signal
170 Abdominal Pain 558 6.5 6.9 signal
171 Product Use In Unapproved Indication 577 6.4 6.8 signal
172 Vomiting 1,082 6.2 7.1 signal
173 Asthenia 831 6.0 6.5 signal
174 Rash 955 5.9 6.6 signal
175 Pruritus 823 5.9 6.4 signal
176 Hepatic Steatosis 40 5.8 5.8 signal
177 Immunodeficiency 31 5.7 5.7 signal
178 Rash Pruritic 113 5.6 5.7 signal
179 Depression 477 5.6 5.9 signal
180 Poisoning 26 5.6 5.6 signal
181 Acute Hepatic Failure 28 5.5 5.6 signal
182 Poisoning Deliberate 19 5.5 5.5 signal
183 Cardiac Arrest 164 5.3 5.4 signal
184 Ventricular Fibrillation 22 5.3 5.3 signal
185 Electrocardiogram Qt Prolonged 71 5.3 5.4 signal
186 Mental Status Changes 54 5.2 5.3 signal
187 Deformity 18 5.2 5.2 signal
188 Nephropathy 18 5.2 5.2 signal
189 Dyspnoea 1,075 5.1 5.8 signal
190 Pain 1,156 5.1 5.8 signal
191 Therapeutic Product Effect Incomplete 132 5.0 5.1 signal
192 Pneumonia 601 5.0 5.3 signal
193 Dizziness 918 5.0 5.5 signal
194 Suicide Attempt 111 4.9 5.0 signal
195 Agitation 134 4.9 5.0 signal
196 Salivary Hypersecretion 18 4.9 4.9 signal
197 Hypokalaemia 82 4.8 4.9 signal
198 Malaise 779 4.8 5.2 signal
199 Leukopenia 87 4.7 4.7 signal
200 Bipolar Disorder 19 4.7 4.7 signal
201 Bronchitis 128 4.6 4.7 signal
202 Gastrooesophageal Reflux Disease 137 4.6 4.7 signal
203 Accidental Overdose 62 4.6 4.6 signal
204 Visual Impairment 207 4.5 4.6 signal
205 Fatigue 1,301 4.5 5.2 signal
206 Fluid Retention 85 4.5 4.5 signal
207 Headache 1,025 4.4 4.9 signal
208 Intentional Product Misuse 142 4.4 4.5 signal
209 Tachycardia 142 4.3 4.4 signal
210 Tinnitus 73 4.3 4.3 signal
211 Cyanosis 25 4.3 4.3 signal
212 Diarrhoea 1,010 4.2 4.7 signal
213 Aspiration 17 4.2 4.2 signal
214 Vitreous Floaters 15 4.1 4.2 signal
215 Cardiomegaly 19 4.1 4.1 signal
216 Upper Respiratory Tract Infection 70 4.1 4.1 signal
217 Respiratory Tract Infection 39 4.0 4.1 signal
218 Underdose 109 4.0 4.1 signal
219 Pain In Extremity 440 4.0 4.2 signal
220 Premature Baby 45 4.0 4.0 signal
221 Coma 71 4.0 4.0 signal
222 Body Height Decreased 16 4.0 4.0 signal
223 Drug Level Increased 24 3.9 3.9 signal
224 Dental Caries 16 3.9 3.9 signal
225 Foetal Exposure During Pregnancy 116 3.8 3.9 signal
226 Accident 17 3.8 3.9 signal
227 Body Temperature Decreased 14 3.8 3.8 signal
228 Back Disorder 23 3.8 3.8 signal
229 Hypotonia 14 3.8 3.8 signal
230 Weight Decreased 386 3.7 3.9 signal
231 Feeling Jittery 26 3.7 3.7 signal
232 Balance Disorder 117 3.6 3.7 signal
233 Mania 22 3.6 3.6 signal
234 Cardiogenic Shock 19 3.6 3.6 signal
235 Nausea 1,019 3.5 3.9 signal
236 Off Label Use 1,114 3.5 3.9 signal
237 Hypothermia 13 3.5 3.5 signal
238 Muscle Rigidity 15 3.4 3.4 signal
239 Pneumonia Aspiration 31 3.3 3.4 signal
240 Hallucination 93 3.3 3.4 signal
241 Skin Disorder 41 3.3 3.3 signal
242 Photophobia 23 3.3 3.3 signal
243 Intentional Drug Misuse 26 3.3 3.3 signal
244 Rhabdomyolysis 51 3.3 3.3 signal
245 Cholelithiasis 40 3.3 3.3 signal
246 Seasonal Allergy 17 3.2 3.2 signal
247 Caesarean Section 14 3.2 3.2 signal
248 Euphoric Mood 12 3.1 3.1 signal
249 Neck Pain 65 3.1 3.1 signal
250 Ventricular Tachycardia 19 3.1 3.1 signal
251 Coagulopathy 19 3.1 3.1 signal
252 Therapy Partial Responder 17 3.0 3.0 signal
253 Premature Delivery 18 3.0 3.0 signal
254 Panic Attack 41 3.0 3.0 signal
255 Anger 38 3.0 3.0 signal
256 Hypotension 221 3.0 3.0 signal
257 Thrombocytopenia 120 2.9 2.9 signal
258 Drug Withdrawal Syndrome Neonatal 16 2.9 2.9 signal
259 Intestinal Perforation 12 2.9 2.9 signal
260 Status Epilepticus 12 2.9 2.9 signal
261 Lactic Acidosis 34 2.9 2.9 signal
262 Ventricular Extrasystoles 11 2.8 2.8 signal
263 Hepatitis 27 2.8 2.8 signal
264 Urinary Incontinence 31 2.8 2.8 signal
265 Supraventricular Tachycardia 10 2.8 2.8 signal
266 Loss Of Consciousness 133 2.8 2.8 signal
267 Affect Lability 10 2.8 2.8 signal
268 Abortion Spontaneous 41 2.7 2.8 signal
269 Acute Respiratory Distress Syndrome 18 2.7 2.7 signal
270 Irritability 61 2.7 2.7 signal
271 Hepatomegaly 10 2.7 2.7 signal
272 Dementia 28 2.7 2.7 signal
273 Bradycardia 53 2.7 2.7 signal
274 Nerve Injury 11 2.7 2.7 signal
275 Psychotic Disorder 29 2.6 2.6 signal
276 Generalised Tonic-clonic Seizure 16 2.6 2.6 signal
277 Somnolence 194 2.6 2.6 signal
278 Apathy 14 2.6 2.6 signal
279 Hyperhidrosis 124 2.6 2.6 signal
280 Gastric Ulcer 18 2.5 2.5 signal
281 Spinal Pain 11 2.5 2.5 signal
282 Disorientation 37 2.5 2.5 signal
283 Urinary Retention 31 2.5 2.5 signal
284 Thyroid Disorder 14 2.4 2.4 signal
285 Tooth Fracture 10 2.4 2.4 signal
286 Constipation 196 2.4 2.5 signal
287 Arrhythmia 43 2.4 2.4 signal
288 Limb Injury 24 2.4 2.4 signal
289 Impaired Work Ability 19 2.4 2.4 signal
290 Abnormal Weight Gain 11 2.4 2.4 signal
291 Hyperglycaemia 32 2.4 2.4 signal
292 Heart Rate Increased 87 2.4 2.4 signal
293 Impaired Driving Ability 10 2.4 2.4 signal
294 Oral Herpes 17 2.4 2.4 signal
295 Increased Tendency To Bruise 8 2.3 2.3 signal
296 Breast Cancer Stage I 8 2.3 2.3 signal
297 Disseminated Intravascular Coagulation 12 2.3 2.3 signal
298 Treatment Noncompliance 46 2.3 2.3 signal
299 Poor Quality Sleep 18 2.3 2.3 signal
300 Nervousness 44 2.3 2.3 signal
301 Adverse Reaction 11 2.2 2.2 signal
302 Atelectasis 8 2.2 2.2 signal
303 Neuralgia 20 2.2 2.2 signal
304 Oxygen Saturation Decreased 46 2.2 2.2 signal
305 Drug Reaction With Eosinophilia And Systemic Symptoms 21 2.2 2.2 signal
306 Heart Rate Decreased 29 2.2 2.2 signal
307 Pneumothorax 13 2.2 2.2 signal
308 Restlessness 30 2.2 2.2 signal
309 Hepatotoxicity 18 2.2 2.2 signal
310 Palpitations 95 2.2 2.2 signal
311 Drug Dependence 132 2.2 2.2 signal
312 Drug Ineffective 1,067 2.2 2.4 signal
313 Libido Decreased 10 2.2 2.2 signal
314 Injection Site Reaction 55 2.2 2.2 signal
315 Dysstasia 23 2.1 2.1 signal
316 Psoriasis 102 2.1 2.1 signal
317 Depressed Mood 41 2.1 2.1 signal
318 Stress 56 2.1 2.1 signal
319 Leukocytosis 14 2.1 2.1 signal
320 Gastroenteritis Viral 14 2.1 2.1 signal
321 Blood Pressure Systolic Increased 15 2.1 2.1 signal
322 Sneezing 17 2.0 2.0 signal
323 Abscess 12 2.0 2.0 signal
324 Sars-cov-2 Test Positive 10 2.0 2.0 signal
325 Shock 17 2.0 2.0 signal
326 Dysarthria 28 2.0 2.0 signal
327 Hypoglycaemia 36 2.0 2.0 no signal
328 Sputum Discoloured 7 2.0 2.0 no signal
329 Skin Ulcer 19 2.0 2.0 no signal
330 Hepatic Function Abnormal 27 2.0 2.0 no signal
331 Respiratory Distress 20 1.9 2.0 no signal
332 Blood Creatine Phosphokinase Increased 21 1.9 1.9 no signal
333 Hospitalisation 109 1.9 1.9 no signal
334 Withdrawal Syndrome 30 1.9 1.9 no signal
335 Emotional Disorder 22 1.9 1.9 no signal
336 Tremor 117 1.9 1.9 no signal
337 Skin Discolouration 32 1.9 1.9 no signal
338 Fall 231 1.9 1.9 no signal
339 Paranoia 12 1.9 1.9 no signal
340 Sluggishness 7 1.9 1.9 no signal
341 Feeling Abnormal 165 1.8 1.9 no signal
342 Splenomegaly 8 1.8 1.8 no signal
343 Abdominal Distension 71 1.8 1.8 no signal
344 Transaminases Increased 15 1.8 1.8 no signal
345 Thirst 12 1.8 1.8 no signal
346 Myoclonus 8 1.8 1.8 no signal
347 Choking 13 1.8 1.8 no signal
348 Dystonia 13 1.8 1.8 no signal
349 Vision Blurred 91 1.8 1.8 no signal
350 Tachypnoea 9 1.8 1.8 no signal
351 Back Pain 152 1.8 1.8 no signal
352 Decreased Activity 7 1.8 1.8 no signal
353 Muscle Twitching 15 1.7 1.7 no signal
354 Disturbance In Attention 35 1.7 1.7 no signal
355 Tendon Rupture 8 1.7 1.7 no signal
356 Middle Insomnia 12 1.7 1.7 no signal
357 Hepatic Encephalopathy 6 1.7 1.7 no signal
358 Grand Mal Convulsion 6 1.7 1.7 no signal
359 Blood Pressure Decreased 42 1.7 1.7 no signal
360 Bone Density Decreased 20 1.7 1.7 no signal
361 Lethargy 36 1.7 1.7 no signal
362 Hyperthyroidism 9 1.7 1.7 no signal
363 Movement Disorder 20 1.7 1.7 no signal
364 Gastroenteritis 9 1.7 1.7 no signal
365 Restless Legs Syndrome 11 1.6 1.6 no signal
366 Gastric Haemorrhage 7 1.6 1.6 no signal
367 Psychomotor Hyperactivity 10 1.6 1.6 no signal
368 Hypoaesthesia Oral 9 1.6 1.6 no signal
369 Blood Iron Decreased 7 1.6 1.6 no signal
370 Motor Dysfunction 6 1.6 1.6 no signal
371 Neuroleptic Malignant Syndrome 7 1.6 1.6 no signal
372 Hemiparesis 10 1.6 1.6 no signal
373 Peripheral Coldness 8 1.6 1.6 no signal
374 Aggression 29 1.6 1.6 no signal
375 Abnormal Behaviour 23 1.6 1.6 no signal
376 Drug Ineffective For Unapproved Indication 32 1.5 1.5 no signal
377 Febrile Neutropenia 38 1.5 1.5 no signal
378 Mental Disorder 25 1.5 1.5 no signal
379 Heart Rate Irregular 13 1.5 1.5 no signal
380 Carpal Tunnel Syndrome 8 1.5 1.5 no signal
381 Respiratory Failure 41 1.5 1.5 no signal
382 Sudden Death 6 1.5 1.5 no signal
383 Altered State Of Consciousness 12 1.5 1.5 no signal
384 Skin Laceration 6 1.5 1.5 no signal
385 Blood Pressure Abnormal 11 1.5 1.5 no signal
386 Drug Withdrawal Syndrome 49 1.5 1.5 no signal
387 Dyskinesia 22 1.5 1.5 no signal
388 Fluid Overload 8 1.5 1.5 no signal
389 Viral Infection 18 1.5 1.5 no signal
390 Cardiomyopathy 8 1.5 1.5 no signal
391 Seizure 62 1.5 1.5 no signal
392 Candida Infection 9 1.5 1.5 no signal
393 Nodule 7 1.4 1.4 no signal
394 Erythema Multiforme 5 1.4 1.4 no signal
395 Speech Disorder 28 1.4 1.4 no signal
396 Upper Gastrointestinal Haemorrhage 9 1.4 1.4 no signal
397 Gastritis 14 1.4 1.4 no signal
398 Immune System Disorder 7 1.4 1.4 no signal
399 Hepatic Failure 16 1.4 1.4 no signal
400 Spinal Disorder 5 1.4 1.4 no signal
401 Product Quality Issue 71 1.4 1.4 no signal
402 Quality Of Life Decreased 7 1.4 1.4 no signal
403 Breast Cancer Female 14 1.4 1.4 no signal
404 Ejection Fraction Decreased 8 1.4 1.4 no signal
405 Haematemesis 13 1.4 1.4 no signal
406 Therapeutic Response Unexpected 23 1.4 1.4 no signal
407 Ischaemic Stroke 9 1.4 1.4 no signal
408 Ataxia 6 1.4 1.4 no signal
409 Unevaluable Event 38 1.4 1.4 no signal
410 Convulsion 29 1.3 1.3 no signal
411 Blood Pressure Fluctuation 12 1.3 1.3 no signal
412 Blindness Unilateral 7 1.3 1.3 no signal
413 Sensory Disturbance 8 1.3 1.3 no signal
414 Hepatitis C 6 1.3 1.3 no signal
415 Initial Insomnia 5 1.3 1.3 no signal
416 Subarachnoid Haemorrhage 5 1.3 1.3 no signal
417 Small Intestinal Obstruction 6 1.3 1.3 no signal
418 Drug Level Decreased 5 1.3 1.3 no signal
419 Subdural Haematoma 7 1.3 1.3 no signal
420 Cholestasis 9 1.3 1.3 no signal
421 Infusion Site Pain 6 1.3 1.3 no signal
422 Abnormal Dreams 13 1.3 1.3 no signal
423 Diabetes Mellitus 35 1.2 1.2 no signal
424 Jaundice 12 1.2 1.2 no signal
425 Lung Infection 7 1.2 1.2 no signal
426 Fistula 5 1.2 1.2 no signal
427 Myocardial Infarction 78 1.2 1.2 no signal
428 Chromaturia 10 1.2 1.2 no signal
429 Pallor 12 1.2 1.2 no signal
430 Hallucination, Auditory 7 1.2 1.2 no signal
431 Muscle Tightness 7 1.2 1.2 no signal
432 Blood Glucose Abnormal 8 1.2 1.2 no signal
433 Thinking Abnormal 8 1.1 1.1 no signal
434 Hepatocellular Injury 6 1.1 1.1 no signal
435 Posterior Reversible Encephalopathy Syndrome 4 1.1 1.1 no signal
436 Impaired Quality Of Life 6 1.1 1.1 no signal
437 International Normalised Ratio Increased 12 1.1 1.1 no signal
438 Mental Impairment 10 1.1 1.1 no signal
439 Parkinsonism 4 1.1 1.1 no signal
440 Bone Pain 24 1.1 1.1 no signal
441 Scar 7 1.1 1.1 no signal
442 Breast Cancer 38 1.1 1.1 no signal
443 Pancreatitis Acute 9 1.1 1.1 no signal
444 Neurotoxicity 7 1.1 1.1 no signal
445 Injection Site Extravasation 5 1.1 1.1 no signal
446 Activities Of Daily Living Impaired 8 1.1 1.1 no signal
447 Incorrect Product Administration Duration 8 1.1 1.1 no signal
448 Dry Throat 4 1.1 1.1 no signal
449 Delusion 6 1.0 1.0 no signal
450 Product Use Complaint 6 1.0 1.0 no signal
451 Suicidal Ideation 34 1.0 1.0 no signal
452 Throat Tightness 10 1.0 1.0 no signal
453 Pharyngitis Streptococcal 4 1.0 1.0 no signal
454 Akathisia 5 1.0 1.0 no signal
455 Skin Reaction 5 1.0 1.0 no signal
456 Nervous System Disorder 11 0.9 0.9 no signal
457 Product Administration Error 7 0.9 0.9 no signal
458 Death 300 0.9 0.9 no signal
459 Nightmare 12 0.9 0.9 no signal
460 Sexual Dysfunction 4 0.9 0.9 no signal
461 Cytopenia 4 0.9 0.9 no signal
462 Retinal Detachment 3 0.9 0.9 no signal
463 Drug Administration Error 10 0.9 0.9 no signal
464 Personality Change 3 0.9 0.9 no signal
465 Cardiac Disorder 30 0.9 0.9 no signal
466 Abdominal Pain Lower 8 0.8 0.8 no signal
467 Mood Swings 10 0.8 0.8 no signal
468 Haemorrhage 32 0.8 0.8 no signal
469 Anorexia 4 0.8 0.8 no signal
470 Incorrect Route Of Drug Administration 11 0.8 0.8 no signal
471 Vaginal Discharge 3 0.8 0.8 no signal
472 Ovarian Cyst 3 0.8 0.8 no signal
473 Intentional Self-injury 6 0.8 0.8 no signal
474 Toxic Skin Eruption 3 0.8 0.8 no signal
475 Femur Fracture 9 0.8 0.8 no signal
476 Peritonitis 6 0.8 0.8 no signal
477 Drug Effect Less Than Expected 4 0.8 0.8 no signal
478 Local Swelling 5 0.8 0.8 no signal
479 Vaginal Haemorrhage 12 0.8 0.8 no signal
480 Breast Pain 3 0.8 0.8 no signal
481 Pelvic Pain 5 0.7 0.7 no signal
482 Injection Site Nodule 3 0.7 0.7 no signal
483 Multiple Sclerosis 13 0.7 0.7 no signal
484 Myocarditis 3 0.7 0.7 no signal
485 Cytokine Release Syndrome 5 0.7 0.7 no signal
486 Internal Haemorrhage 3 0.7 0.7 no signal
487 Drug Exposure During Pregnancy 9 0.7 0.7 no signal
488 Procedural Pain 7 0.7 0.7 no signal
489 Blood Glucose Decreased 12 0.7 0.7 no signal
490 Schizophrenia 3 0.7 0.7 no signal
491 Tardive Dyskinesia 7 0.7 0.7 no signal
492 Metastases To Bone 4 0.7 0.7 no signal
493 Ankylosing Spondylitis 3 0.6 0.6 no signal
494 Injection Site Haemorrhage 18 0.6 0.6 no signal
495 Device Occlusion 3 0.6 0.6 no signal
496 Acne 16 0.6 0.6 no signal
497 Emotional Distress 25 0.6 0.6 no signal
498 Injection Site Rash 6 0.5 0.5 no signal
499 Therapeutic Response Shortened 6 0.5 0.5 no signal
500 Accidental Exposure To Product 18 0.5 0.5 no signal
501 Incorrect Drug Administration Duration 5 0.5 0.5 no signal
502 Palmar-plantar Erythrodysaesthesia Syndrome 4 0.5 0.5 no signal
503 Product Complaint 4 0.4 0.4 no signal
504 Extrapyramidal Disorder 4 0.4 0.4 no signal
505 Incorrect Dose Administered By Device 4 0.4 0.4 no signal
506 Product Preparation Error 3 0.4 0.4 no signal
507 Multiple Sclerosis Relapse 10 0.4 0.4 no signal
508 Injection Site Bruising 11 0.4 0.4 no signal
509 Wrong Technique In Drug Usage Process 5 0.4 0.4 no signal
510 Gynaecomastia 4 0.3 0.3 no signal
511 Injection Site Urticaria 3 0.3 0.3 no signal
512 Device Dislocation 5 0.3 0.3 no signal
513 Dependence 6 0.3 0.3 no signal
514 Device Breakage 3 0.2 0.2 no signal
515 Renal Cancer 3 0.2 0.2 no signal