Drug
Calcium Carbonate, Magnesium Hydroxide
Important: Reactions below are the flagged terms from this drug’s
FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate
disproportionality in spontaneous reporting, not causation.
Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
| Reaction | Co-reports (a) | PRR | ROR | Signal | |
|---|---|---|---|---|---|
| 1 | End Stage Renal Disease | 576 | 230.1 | 285.8 | signal |
| 2 | Chronic Kidney Disease | 1,897 | 180.8 | 507.0 | signal |
| 3 | Renal Injury | 430 | 103.5 | 121.1 | signal |
| 4 | Multiple Fractures | 161 | 69.9 | 73.9 | signal |
| 5 | Tubulointerstitial Nephritis | 175 | 67.2 | 71.4 | signal |
| 6 | Vitamin D Deficiency | 87 | 64.2 | 66.1 | signal |
| 7 | Renal Failure | 1,019 | 54.7 | 83.1 | signal |
| 8 | Bone Disorder | 137 | 53.5 | 56.1 | signal |
| 9 | Acute Kidney Injury | 1,087 | 51.2 | 80.6 | signal |
| 10 | Osteoporosis | 283 | 49.3 | 54.4 | signal |
| 11 | Nephropathy | 56 | 42.8 | 43.6 | signal |
| 12 | Intervertebral Disc Degeneration | 50 | 38.5 | 39.1 | signal |
| 13 | Renal Tubular Necrosis | 52 | 37.9 | 38.5 | signal |
| 14 | Gastrooesophageal Reflux Disease | 382 | 34.1 | 39.0 | signal |
| 15 | Osteopenia | 67 | 31.4 | 32.1 | signal |
| 16 | Foot Fracture | 70 | 26.3 | 26.9 | signal |
| 17 | Ankle Fracture | 52 | 24.0 | 24.4 | signal |
| 18 | Wrist Fracture | 34 | 20.3 | 20.5 | signal |
| 19 | Arthritis | 174 | 15.8 | 16.7 | signal |
| 20 | Osteoarthritis | 82 | 13.8 | 14.1 | signal |
| 21 | Bipolar Disorder | 21 | 13.7 | 13.8 | signal |
| 22 | Back Disorder | 31 | 13.6 | 13.7 | signal |
| 23 | Carpal Tunnel Syndrome | 25 | 12.7 | 12.8 | signal |
| 24 | Intervertebral Disc Protrusion | 39 | 12.7 | 12.9 | signal |
| 25 | Back Injury | 19 | 12.5 | 12.6 | signal |
| 26 | Lower Limb Fracture | 33 | 12.3 | 12.5 | signal |
| 27 | Spinal Disorder | 16 | 12.0 | 12.1 | signal |
| 28 | Upper Limb Fracture | 33 | 11.8 | 11.9 | signal |
| 29 | Ligament Sprain | 16 | 11.6 | 11.6 | signal |
| 30 | Gallbladder Disorder | 27 | 10.8 | 10.8 | signal |
| 31 | Bone Density Decreased | 47 | 10.6 | 10.7 | signal |
| 32 | Rib Fracture | 30 | 10.4 | 10.5 | signal |
| 33 | Product Odour Abnormal | 15 | 10.3 | 10.4 | signal |
| 34 | Joint Dislocation | 14 | 9.5 | 9.5 | signal |
| 35 | Glaucoma | 24 | 8.9 | 8.9 | signal |
| 36 | Dyspepsia | 117 | 8.5 | 8.8 | signal |
| 37 | Spinal Fracture | 22 | 7.9 | 7.9 | signal |
| 38 | Joint Injury | 23 | 7.7 | 7.7 | signal |
| 39 | Angina Pectoris | 30 | 7.4 | 7.5 | signal |
| 40 | Chronic Obstructive Pulmonary Disease | 51 | 7.0 | 7.1 | signal |
| 41 | Depression | 218 | 6.8 | 7.3 | signal |
| 42 | Renal Impairment | 76 | 6.5 | 6.6 | signal |
| 43 | Gastric Cancer | 23 | 6.4 | 6.4 | signal |
| 44 | Coronary Artery Disease | 27 | 6.3 | 6.4 | signal |
| 45 | Diabetes Mellitus | 66 | 6.1 | 6.3 | signal |
| 46 | Rotator Cuff Syndrome | 11 | 6.1 | 6.1 | signal |
| 47 | Bone Pain | 50 | 6.1 | 6.2 | signal |
| 48 | Hip Fracture | 27 | 6.0 | 6.0 | signal |
| 49 | Limb Injury | 21 | 5.5 | 5.6 | signal |
| 50 | Arthropathy | 42 | 5.4 | 5.4 | signal |
| 51 | Gastric Disorder | 26 | 5.3 | 5.4 | signal |
| 52 | Impaired Work Ability | 16 | 5.3 | 5.3 | signal |
| 53 | Nephrolithiasis | 34 | 5.3 | 5.3 | signal |
| 54 | Fibromyalgia | 18 | 5.3 | 5.3 | signal |
| 55 | Tooth Fracture | 8 | 5.2 | 5.2 | signal |
| 56 | Hiatus Hernia | 9 | 4.9 | 5.0 | signal |
| 57 | Eructation | 13 | 4.9 | 4.9 | signal |
| 58 | Product Taste Abnormal | 9 | 4.8 | 4.8 | signal |
| 59 | Bone Loss | 10 | 4.7 | 4.7 | signal |
| 60 | Hepatitis C | 8 | 4.7 | 4.7 | signal |
| 61 | Musculoskeletal Discomfort | 11 | 4.6 | 4.6 | signal |
| 62 | Fracture | 12 | 4.5 | 4.5 | signal |
| 63 | Cardiovascular Disorder | 16 | 4.5 | 4.5 | signal |
| 64 | Gout | 11 | 4.4 | 4.4 | signal |
| 65 | Type 2 Diabetes Mellitus | 20 | 4.2 | 4.2 | signal |
| 66 | Renal Disorder | 27 | 4.1 | 4.2 | signal |
| 67 | Cataract | 32 | 3.8 | 3.9 | signal |
| 68 | Thyroid Disorder | 8 | 3.7 | 3.7 | signal |
| 69 | Cholecystitis | 6 | 3.6 | 3.6 | signal |
| 70 | Bladder Disorder | 5 | 3.6 | 3.6 | signal |
| 71 | Hypothyroidism | 16 | 3.6 | 3.6 | signal |
| 72 | Road Traffic Accident | 21 | 3.6 | 3.6 | signal |
| 73 | Renal Pain | 5 | 3.4 | 3.4 | signal |
| 74 | Kidney Infection | 9 | 3.3 | 3.3 | signal |
| 75 | Economic Problem | 7 | 3.2 | 3.2 | signal |
| 76 | Rebound Effect | 5 | 3.1 | 3.1 | signal |
| 77 | Irritable Bowel Syndrome | 9 | 3.0 | 3.0 | signal |
| 78 | Femur Fracture | 13 | 3.0 | 3.0 | signal |
| 79 | Rheumatoid Arthritis | 47 | 3.0 | 3.0 | signal |
| 80 | Product Quality Issue | 51 | 2.7 | 2.7 | signal |
| 81 | Body Height Decreased | 4 | 2.6 | 2.6 | no signal |
| 82 | Activities Of Daily Living Impaired | 7 | 2.5 | 2.5 | signal |
| 83 | Intentional Drug Misuse | 7 | 2.4 | 2.4 | signal |
| 84 | Skin Cancer | 7 | 2.3 | 2.3 | no signal |
| 85 | Lymphoma | 5 | 2.3 | 2.3 | no signal |
| 86 | Cardiac Failure Congestive | 26 | 2.3 | 2.3 | signal |
| 87 | Hernia | 6 | 2.2 | 2.2 | no signal |
| 88 | Cardiac Disorder | 28 | 2.1 | 2.1 | signal |
| 89 | Skeletal Injury | 3 | 2.0 | 2.0 | no signal |
| 90 | Incorrect Drug Administration Duration | 8 | 2.0 | 2.0 | no signal |
| 91 | Convulsion | 16 | 2.0 | 2.0 | no signal |
| 92 | Anosmia | 4 | 2.0 | 2.0 | no signal |
| 93 | Renal Cancer | 12 | 1.8 | 1.8 | no signal |
| 94 | Drug Dose Omission | 38 | 1.6 | 1.6 | no signal |
| 95 | Blood Glucose Abnormal | 4 | 1.5 | 1.5 | no signal |
| 96 | Drug Exposure During Pregnancy | 7 | 1.4 | 1.4 | no signal |
| 97 | Oesophageal Carcinoma | 5 | 1.2 | 1.2 | no signal |
| 98 | Breast Cancer Female | 4 | 1.1 | 1.1 | no signal |
| 99 | Prostate Cancer | 10 | 0.9 | 0.9 | no signal |
| 100 | Breast Cancer | 9 | 0.7 | 0.7 | no signal |
| 101 | Bladder Cancer | 4 | 0.5 | 0.5 | no signal |