OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Calcium Chloride

340 flagged reaction(s) · 19,891 total co-reports · max PRR 123.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Pemphigus 218 123.8 133.4 signal
2 Helicobacter Infection 119 81.9 85.3 signal
3 Pericarditis 179 75.3 80.0 signal
4 Folliculitis 101 68.5 70.8 signal
5 Hand Deformity 123 65.8 68.6 signal
6 Multi-organ Failure 133 53.0 55.4 signal
7 Liver Injury 178 51.4 54.6 signal
8 Prescribed Overdose 138 49.8 52.2 signal
9 Autoimmune Disorder 67 48.9 50.0 signal
10 Pulmonary Fibrosis 133 48.6 50.8 signal
11 Synovitis 124 48.0 50.0 signal
12 Fear 184 47.4 50.4 signal
13 Irritable Bowel Syndrome 137 44.8 46.8 signal
14 Lower Limb Fracture 120 43.9 45.6 signal
15 Injury 407 40.2 46.3 signal
16 Type 2 Diabetes Mellitus 191 39.5 42.1 signal
17 Renal Injury 168 39.0 41.3 signal
18 Toxic Epidermal Necrolysis 83 38.4 39.5 signal
19 Glossodynia 116 36.2 37.6 signal
20 Anhedonia 128 33.7 35.1 signal
21 Sciatica 75 33.0 33.8 signal
22 Psoriatic Arthropathy 180 31.2 33.1 signal
23 Fibromyalgia 107 30.7 31.8 signal
24 Prescribed Underdose 86 30.0 30.9 signal
25 Wound Infection 44 28.2 28.6 signal
26 Contraindicated Product Administered 119 27.5 28.6 signal
27 Oedema 213 27.4 29.4 signal
28 Hypercholesterolaemia 37 26.9 27.3 signal
29 Cardiogenic Shock 50 24.4 24.8 signal
30 Systemic Lupus Erythematosus 117 23.0 23.9 signal
31 Joint Range Of Motion Decreased 42 21.9 22.2 signal
32 Lower Respiratory Tract Infection 142 21.8 22.8 signal
33 Impaired Healing 102 21.6 22.3 signal
34 Blood Calcium Decreased 35 21.6 21.8 signal
35 Bursitis 37 21.3 21.6 signal
36 Wound 85 21.3 21.9 signal
37 Incorrect Route Of Product Administration 51 21.1 21.5 signal
38 Blood Cholesterol Increased 136 20.3 21.2 signal
39 Sleep Disorder 199 19.8 21.1 signal
40 Therapy Non-responder 122 19.0 19.8 signal
41 Unevaluable Event 205 18.8 20.1 signal
42 Stomatitis 164 18.8 19.8 signal
43 Ventricular Fibrillation 30 18.7 18.9 signal
44 Mobility Decreased 192 18.6 19.8 signal
45 Liver Disorder 116 18.2 18.9 signal
46 Therapeutic Product Effect Decreased 113 17.7 18.4 signal
47 Gait Inability 84 17.7 18.1 signal
48 Blister 137 17.0 17.8 signal
49 Emphysema 24 16.5 16.6 signal
50 Hypercalcaemia 29 16.4 16.5 signal
51 Hepatitis 60 16.3 16.6 signal
52 Stress 166 16.0 16.9 signal
53 Body Temperature Decreased 22 15.4 15.5 signal
54 Status Epilepticus 25 15.4 15.5 signal
55 Wheezing 128 15.0 15.7 signal
56 Renal Impairment 173 14.4 15.2 signal
57 Blood Test Abnormal 29 14.4 14.5 signal
58 Infusion Related Reaction 136 14.3 14.9 signal
59 Hip Arthroplasty 31 14.2 14.3 signal
60 Renal Failure 273 14.2 15.5 signal
61 Therapeutic Response Decreased 123 14.2 14.7 signal
62 Laryngitis 22 14.1 14.2 signal
63 Disability 39 13.7 13.9 signal
64 Drug-induced Liver Injury 60 13.5 13.8 signal
65 Appendicitis 18 13.5 13.5 signal
66 Road Traffic Accident 81 13.5 13.8 signal
67 Adverse Reaction 25 13.1 13.2 signal
68 Discomfort 110 12.6 13.1 signal
69 Foot Deformity 20 12.5 12.6 signal
70 Sinusitis 185 12.5 13.3 signal
71 Joint Swelling 214 12.3 13.2 signal
72 Face Oedema 30 12.3 12.4 signal
73 Rash Pruritic 94 12.1 12.5 signal
74 Arthropathy 97 12.1 12.5 signal
75 Pregnancy 35 12.0 12.2 signal
76 Hepatic Enzyme Increased 114 11.7 12.1 signal
77 Drug Intolerance 160 11.6 12.1 signal
78 Pneumothorax 26 11.4 11.5 signal
79 Migraine 155 11.4 11.9 signal
80 Maternal Exposure During Pregnancy 144 11.3 11.9 signal
81 Obesity 26 11.3 11.4 signal
82 Swelling 149 11.1 11.6 signal
83 Encephalopathy 39 11.1 11.2 signal
84 Dyspepsia 153 10.8 11.4 signal
85 General Physical Health Deterioration 179 10.8 11.4 signal
86 Leukopenia 76 10.6 10.8 signal
87 Respiratory Failure 111 10.6 10.9 signal
88 Renal Failure Acute 65 10.5 10.7 signal
89 Adrenal Insufficiency 18 10.4 10.5 signal
90 Multiple Organ Dysfunction Syndrome 41 10.2 10.3 signal
91 Ascites 43 10.2 10.3 signal
92 Asthma 162 10.0 10.6 signal
93 Hepatic Cirrhosis 27 10.0 10.1 signal
94 Red Blood Cell Sedimentation Rate Increased 16 10.0 10.1 signal
95 Cytokine Release Syndrome 27 9.8 9.9 signal
96 Anaphylactic Shock 36 9.8 9.9 signal
97 Knee Arthroplasty 29 9.7 9.7 signal
98 Treatment Failure 112 9.5 9.8 signal
99 Conjunctivitis 25 9.5 9.5 signal
100 Shock 31 9.4 9.5 signal
101 Emotional Distress 164 9.4 9.9 signal
102 Musculoskeletal Stiffness 118 9.4 9.7 signal
103 Joint Dislocation 14 9.2 9.3 signal
104 Aspiration 14 9.0 9.0 signal
105 Intentional Product Use Issue 111 8.8 9.1 signal
106 Tachypnoea 17 8.7 8.8 signal
107 Bacterial Infection 23 8.6 8.7 signal
108 Pleural Effusion 75 8.6 8.7 signal
109 Hypocalcaemia 23 8.5 8.5 signal
110 Hypotension 244 8.5 9.1 signal
111 Electrolyte Imbalance 14 8.5 8.5 signal
112 Sudden Death 13 8.4 8.5 signal
113 Injection Site Extravasation 15 8.3 8.4 signal
114 Urticaria 198 8.3 8.8 signal
115 Mouth Ulceration 25 8.3 8.3 signal
116 Acute Respiratory Distress Syndrome 21 8.2 8.3 signal
117 Motor Dysfunction 12 8.2 8.3 signal
118 Delirium 41 8.2 8.3 signal
119 Rheumatoid Arthritis 133 8.2 8.5 signal
120 Arteriosclerosis 11 8.1 8.1 signal
121 Obstructive Airways Disorder 13 8.1 8.1 signal
122 Full Blood Count Abnormal 12 7.9 7.9 signal
123 Gastrointestinal Disorder 99 7.8 8.0 signal
124 Ill-defined Disorder 67 7.7 7.8 signal
125 Night Sweats 35 7.5 7.6 signal
126 Hyperlipidaemia 13 7.5 7.6 signal
127 Coagulopathy 18 7.5 7.6 signal
128 Osteoarthritis 46 7.5 7.6 signal
129 Blood Urea Increased 18 7.4 7.5 signal
130 Joint Stiffness 28 7.4 7.5 signal
131 Metabolic Acidosis 33 7.2 7.3 signal
132 Lung Disorder 51 7.2 7.3 signal
133 Sinus Bradycardia 10 7.2 7.2 signal
134 Hypoxia 36 7.1 7.2 signal
135 Blood Pressure Systolic Increased 20 7.1 7.1 signal
136 Anxiety 291 7.1 7.7 signal
137 Ear Infection 27 7.1 7.1 signal
138 Sleep Disorder Due To A General Medical Condition 16 6.9 6.9 signal
139 Exposure During Pregnancy 61 6.8 6.9 signal
140 Drug Hypersensitivity 190 6.8 7.2 signal
141 Ear Pain 19 6.8 6.8 signal
142 Generalised Oedema 12 6.8 6.8 signal
143 Respiratory Disorder 29 6.7 6.8 signal
144 Neuralgia 23 6.6 6.6 signal
145 Acute Respiratory Failure 18 6.5 6.6 signal
146 Gait Disturbance 179 6.5 6.8 signal
147 Cardiac Arrest 77 6.5 6.6 signal
148 Back Injury 10 6.4 6.4 signal
149 Bradycardia 49 6.4 6.5 signal
150 Nodule 12 6.4 6.4 signal
151 Hypertension 192 6.3 6.6 signal
152 Ventricular Tachycardia 15 6.3 6.3 signal
153 Taste Disorder 18 6.2 6.3 signal
154 Circulatory Collapse 15 6.1 6.1 signal
155 Iron Deficiency Anaemia 8 6.0 6.1 signal
156 Pulmonary Hypertension 18 6.0 6.0 signal
157 Septic Shock 37 5.9 6.0 signal
158 Contusion 82 5.9 6.1 signal
159 Disseminated Intravascular Coagulation 12 5.9 5.9 signal
160 Sinus Tachycardia 12 5.9 5.9 signal
161 Sputum Discoloured 8 5.9 5.9 signal
162 Loss Of Personal Independence In Daily Activities 40 5.8 5.9 signal
163 Confusional State 136 5.8 6.1 signal
164 Hypersensitivity 154 5.8 6.0 signal
165 Fluid Overload 12 5.6 5.7 signal
166 Nasopharyngitis 150 5.6 5.9 signal
167 Dry Mouth 65 5.6 5.7 signal
168 Hyperkalaemia 28 5.6 5.6 signal
169 Tachycardia 71 5.5 5.7 signal
170 Liver Function Test Increased 17 5.5 5.6 signal
171 Peripheral Swelling 122 5.5 5.7 signal
172 Gout 14 5.4 5.4 signal
173 Pyrexia 268 5.4 5.8 signal
174 Vasculitis 9 5.4 5.4 signal
175 Post Procedural Haemorrhage 9 5.4 5.4 signal
176 C-reactive Protein Increased 28 5.3 5.4 signal
177 Sepsis 85 5.3 5.4 signal
178 End Stage Renal Disease 14 5.3 5.3 signal
179 Abdominal Discomfort 127 5.3 5.5 signal
180 Infection 109 5.2 5.4 signal
181 Staphylococcal Infection 25 5.2 5.3 signal
182 Ulcer 12 5.2 5.2 signal
183 Immunodeficiency 11 5.2 5.2 signal
184 Blood Potassium Increased 12 5.1 5.2 signal
185 Medication Error 41 5.1 5.2 signal
186 Blood Triglycerides Increased 13 5.1 5.1 signal
187 Cholelithiasis 24 5.1 5.1 signal
188 Oesophagitis 8 5.1 5.1 signal
189 Osteoporosis 30 5.1 5.1 signal
190 Adverse Event 67 5.0 5.1 signal
191 Product Use In Unapproved Indication 177 5.0 5.3 signal
192 Epilepsy 22 5.0 5.0 signal
193 Leukocytosis 13 5.0 5.0 signal
194 Condition Aggravated 217 5.0 5.3 signal
195 Product Use Issue 134 5.0 5.2 signal
196 Intestinal Perforation 8 4.9 5.0 signal
197 Renal Tubular Necrosis 7 4.9 5.0 signal
198 Hypoaesthesia 106 4.9 5.1 signal
199 Flatulence 40 4.9 5.0 signal
200 Ejection Fraction Decreased 11 4.9 4.9 signal
201 Pain 427 4.8 5.4 signal
202 Blood Pressure Decreased 46 4.8 4.9 signal
203 Anaphylactic Reaction 38 4.8 4.9 signal
204 Anorexia 9 4.8 4.8 signal
205 Respiratory Distress 19 4.8 4.8 signal
206 Pain In Extremity 203 4.8 5.0 signal
207 Weight Increased 153 4.8 5.0 signal
208 Initial Insomnia 7 4.8 4.8 signal
209 Alopecia 134 4.7 4.9 signal
210 Cholestasis 13 4.7 4.7 signal
211 Pneumonia 217 4.7 4.9 signal
212 Tenderness 7 4.7 4.7 signal
213 Chromaturia 15 4.6 4.6 signal
214 Cytomegalovirus Infection 11 4.6 4.6 signal
215 Cardiomegaly 8 4.5 4.5 signal
216 Tooth Extraction 8 4.5 4.5 signal
217 Chest Pain 119 4.5 4.6 signal
218 Grand Mal Convulsion 6 4.4 4.5 signal
219 Deformity 6 4.4 4.5 signal
220 Abdominal Pain Upper 131 4.4 4.6 signal
221 Body Temperature Increased 13 4.4 4.4 signal
222 Insomnia 169 4.4 4.6 signal
223 Hepatic Failure 19 4.4 4.4 signal
224 Amnesia 41 4.4 4.4 signal
225 Musculoskeletal Pain 33 4.3 4.4 signal
226 Inflammation 32 4.3 4.4 signal
227 Unresponsive To Stimuli 16 4.3 4.3 signal
228 Skin Ulcer 16 4.3 4.3 signal
229 Accidental Overdose 22 4.2 4.2 signal
230 Abdominal Pain 139 4.2 4.3 signal
231 Brain Injury 6 4.1 4.2 signal
232 Intentional Overdose 38 4.1 4.2 signal
233 Thrombosis 48 4.1 4.2 signal
234 Hypothermia 6 4.1 4.1 signal
235 Osteopenia 9 4.1 4.1 signal
236 Epistaxis 44 4.1 4.1 signal
237 Muscle Rigidity 7 4.1 4.1 signal
238 Device Related Infection 9 4.0 4.1 signal
239 Hyperbilirubinaemia 6 4.0 4.0 signal
240 Eosinophilia 10 4.0 4.0 signal
241 Cyanosis 9 4.0 4.0 signal
242 Pulmonary Embolism 54 3.9 4.0 signal
243 Depression 128 3.9 4.0 signal
244 Bronchospasm 8 3.9 3.9 signal
245 Spinal Fracture 11 3.8 3.8 signal
246 Generalised Tonic-clonic Seizure 9 3.8 3.8 signal
247 Cardio-respiratory Arrest 23 3.8 3.8 signal
248 Decreased Appetite 125 3.7 3.9 signal
249 Chronic Obstructive Pulmonary Disease 28 3.7 3.8 signal
250 Haemoptysis 15 3.7 3.7 signal
251 Adverse Drug Reaction 48 3.7 3.8 signal
252 Pulmonary Oedema 24 3.7 3.7 signal
253 Laceration 5 3.6 3.6 signal
254 Hyperglycaemia 19 3.6 3.6 signal
255 Post Procedural Complication 10 3.6 3.6 signal
256 Coeliac Disease 5 3.5 3.5 signal
257 Blood Iron Decreased 6 3.5 3.5 signal
258 Colitis 19 3.5 3.5 signal
259 Bladder Disorder 5 3.5 3.5 signal
260 Electrocardiogram Qt Prolonged 18 3.5 3.5 signal
261 Febrile Neutropenia 33 3.5 3.5 signal
262 Lymphopenia 7 3.5 3.5 signal
263 Haematuria 17 3.4 3.5 signal
264 Arthritis 39 3.4 3.5 signal
265 Pain In Jaw 14 3.4 3.4 signal
266 Deep Vein Thrombosis 32 3.4 3.4 signal
267 Bone Disorder 9 3.4 3.4 signal
268 Respiratory Depression 6 3.4 3.4 signal
269 Small Intestinal Obstruction 6 3.4 3.4 signal
270 Subdural Haematoma 7 3.4 3.4 signal
271 No Therapeutic Response 6 3.4 3.4 signal
272 Tendon Rupture 6 3.4 3.4 signal
273 Tubulointerstitial Nephritis 9 3.3 3.3 signal
274 Weight Fluctuation 5 3.3 3.3 signal
275 Nervousness 25 3.3 3.3 signal
276 Haemorrhage Intracranial 7 3.2 3.2 signal
277 Metastases To Liver 8 3.2 3.2 signal
278 Pneumonitis 12 3.1 3.1 signal
279 Myocardial Ischaemia 5 3.0 3.0 signal
280 Device Occlusion 6 3.0 3.0 signal
281 Drug Reaction With Eosinophilia And Systemic Symptoms 11 3.0 3.0 signal
282 Feeling Cold 12 3.0 3.0 signal
283 Loss Of Consciousness 55 3.0 3.0 signal
284 Back Disorder 7 3.0 3.0 signal
285 Metastases To Bone 7 3.0 3.0 signal
286 Feeling Hot 26 2.9 3.0 signal
287 Haematoma 11 2.9 2.9 signal
288 Hemiparesis 7 2.8 2.9 signal
289 Frequent Bowel Movements 11 2.8 2.8 signal
290 Arthralgia 169 2.8 2.9 signal
291 Pneumocystis Jirovecii Pneumonia 4 2.8 2.8 no signal
292 Fluid Retention 20 2.7 2.7 signal
293 Osteonecrosis 13 2.7 2.7 signal
294 Peritonitis 8 2.7 2.7 signal
295 Impaired Work Ability 8 2.6 2.6 signal
296 Haemorrhage 38 2.5 2.5 signal
297 Respiratory Arrest 10 2.5 2.5 signal
298 Blindness Unilateral 5 2.5 2.5 no signal
299 Cardiac Disorder 33 2.4 2.5 signal
300 Mucosal Inflammation 9 2.4 2.4 signal
301 Pulmonary Arterial Hypertension 5 2.4 2.4 no signal
302 Bone Marrow Failure 7 2.4 2.4 signal
303 Macular Degeneration 4 2.3 2.3 no signal
304 Cerebrovascular Accident 57 2.3 2.4 signal
305 Hepatic Cytolysis 4 2.3 2.3 no signal
306 Intentional Product Misuse 28 2.2 2.2 signal
307 Abasia 8 2.2 2.2 signal
308 Needle Issue 9 2.2 2.2 signal
309 Feeling Jittery 6 2.2 2.2 no signal
310 Premature Delivery 5 2.2 2.2 no signal
311 Complication Associated With Device 4 2.1 2.1 no signal
312 Toxicity To Various Agents 50 2.1 2.1 signal
313 Acute Hepatic Failure 4 2.0 2.0 no signal
314 Colitis Ulcerative 13 2.0 2.0 signal
315 Drug Toxicity 4 2.0 2.0 no signal
316 Malignant Neoplasm Progression 29 2.0 2.0 no signal
317 Dialysis 4 2.0 2.0 no signal
318 Lactic Acidosis 9 1.9 1.9 no signal
319 Nephropathy Toxic 3 1.9 1.9 no signal
320 Myocarditis 3 1.8 1.8 no signal
321 Convulsion 15 1.8 1.8 no signal
322 Lymphoma 4 1.8 1.8 no signal
323 Caesarean Section 3 1.8 1.8 no signal
324 Cytopenia 3 1.7 1.7 no signal
325 Abnormal Behaviour 10 1.7 1.7 no signal
326 Premature Baby 7 1.6 1.6 no signal
327 Pharmaceutical Product Complaint 6 1.6 1.6 no signal
328 Uveitis 3 1.5 1.5 no signal
329 Drug Dispensing Error 3 1.3 1.3 no signal
330 Product Quality Issue 26 1.3 1.3 no signal
331 Psoriasis 23 1.2 1.2 no signal
332 Drug Exposure During Pregnancy 6 1.2 1.2 no signal
333 Foetal Exposure During Pregnancy 14 1.2 1.2 no signal
334 Syringe Issue 3 1.2 1.2 no signal
335 Injection Site Rash 5 1.1 1.1 no signal
336 Injury Associated With Device 3 1.0 1.0 no signal
337 Incorrect Route Of Drug Administration 5 1.0 1.0 no signal
338 Abortion Spontaneous 5 0.9 0.9 no signal
339 Wrong Technique In Device Usage Process 4 0.6 0.6 no signal
340 Device Difficult To Use 4 0.4 0.4 no signal