Drug

Capsaicin

105 flagged reaction(s) · 4,096 total co-reports · max PRR 163.3

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Application Site Pain	547	163.3	195.9	signal
2	Application Site Erythema	149	36.5	38.2	signal
3	Hyperlipidaemia	63	33.9	34.5	signal
4	Impaired Quality Of Life	68	30.4	31.1	signal
5	Burning Sensation	329	30.2	33.5	signal
6	Poor Quality Sleep	77	23.1	23.7	signal
7	Impaired Work Ability	68	20.4	20.8	signal
8	Oral Herpes	57	18.8	19.2	signal
9	Neuralgia	50	13.2	13.4	signal
10	Bone Density Decreased	62	12.6	12.8	signal
11	Skin Disorder	61	11.8	12.0	signal
12	Cellulitis	65	8.3	8.4	signal
13	Herpes Zoster	74	8.3	8.4	signal
14	Quality Of Life Decreased	17	8.1	8.2	signal
15	Feeling Hot	74	7.7	7.9	signal
16	Drug Eruption	21	7.6	7.7	signal
17	Cataract	70	7.6	7.7	signal
18	Sleep Apnoea Syndrome	22	7.4	7.4	signal
19	Therapy Non-responder	50	7.2	7.3	signal
20	Blister	58	6.6	6.7	signal
21	Limb Discomfort	31	6.4	6.5	signal
22	Application Site Rash	13	6.0	6.1	signal
23	Application Site Pruritus	21	5.9	6.0	signal
24	Paraesthesia Oral	12	5.4	5.4	signal
25	Glaucoma	16	5.3	5.3	signal
26	No Therapeutic Response	10	5.2	5.2	signal
27	Application Site Irritation	10	5.2	5.2	signal
28	Economic Problem	12	5.0	5.0	signal
29	Paralysis	11	4.9	4.9	signal
30	Therapeutic Product Effect Incomplete	54	4.9	5.0	signal
31	Liver Function Test Increased	16	4.8	4.8	signal
32	Sensory Disturbance	12	4.8	4.8	signal
33	Pain In Extremity	215	4.7	4.9	signal
34	Contusion	69	4.6	4.7	signal
35	Hypertensive Crisis	8	4.6	4.6	signal
36	Throat Irritation	32	4.6	4.6	signal
37	Pain	425	4.4	4.9	signal
38	Product Administered At Inappropriate Site	12	4.2	4.2	signal
39	Paraesthesia	101	4.1	4.2	signal
40	Osteoarthritis	27	4.1	4.1	signal
41	Presyncope	15	4.0	4.0	signal
42	Hypoaesthesia	90	3.9	3.9	signal
43	Ataxia	7	3.8	3.8	signal
44	Acute Respiratory Distress Syndrome	10	3.6	3.6	signal
45	Therapeutic Product Effect Decreased	24	3.5	3.5	signal
46	Chromaturia	12	3.4	3.4	signal
47	Skin Burning Sensation	37	3.3	3.4	signal
48	Ejection Fraction Decreased	8	3.3	3.3	signal
49	Swollen Tongue	16	3.3	3.3	signal
50	Peripheral Coldness	7	3.3	3.3	signal
51	Ligament Sprain	5	3.2	3.3	signal
52	Myoclonus	6	3.2	3.2	signal
53	Temperature Intolerance	5	3.1	3.1	signal
54	Neuropathy Peripheral	45	3.1	3.1	signal
55	Anaphylactic Reaction	26	3.0	3.1	signal
56	Circulatory Collapse	8	3.0	3.0	signal
57	Weight Increased	102	2.9	3.0	signal
58	Lip Swelling	15	2.9	2.9	signal
59	Erythema	91	2.8	2.9	signal
60	Oral Discomfort	6	2.8	2.8	signal
61	Tooth Loss	9	2.8	2.8	signal
62	Skin Reaction	6	2.7	2.7	signal
63	Sedation	11	2.7	2.7	signal
64	Bronchospasm	6	2.7	2.7	signal
65	Skin Haemorrhage	6	2.7	2.7	signal
66	Anhedonia	11	2.7	2.7	signal
67	Drug Ineffective For Unapproved Indication	23	2.6	2.7	signal
68	Throat Tightness	11	2.6	2.6	signal
69	Withdrawal Syndrome	17	2.6	2.6	signal
70	Bladder Disorder	4	2.6	2.6	no signal
71	Dermatitis Allergic	5	2.6	2.6	no signal
72	Hallucination, Visual	8	2.4	2.4	signal
73	Treatment Failure	31	2.4	2.4	signal
74	Adverse Reaction	5	2.4	2.4	no signal
75	Eye Irritation	21	2.4	2.4	signal
76	Breast Pain	4	2.4	2.4	no signal
77	Bipolar Disorder	4	2.3	2.3	no signal
78	Internal Haemorrhage	4	2.2	2.2	no signal
79	Product Prescribing Issue	7	2.2	2.2	no signal
80	Accidental Exposure To Product	34	2.2	2.2	signal
81	Product Adhesion Issue	12	2.2	2.2	signal
82	Eye Pruritus	11	2.1	2.1	signal
83	Tendon Rupture	4	2.1	2.1	no signal
84	Incorrect Drug Administration Duration	9	2.0	2.0	no signal
85	Metastases To Bone	5	2.0	2.0	no signal
86	Disability	6	1.9	1.9	no signal
87	Uveitis	4	1.9	1.9	no signal
88	Angioedema	13	1.9	1.9	no signal
89	Product Odour Abnormal	3	1.9	1.9	no signal
90	Drug Administered At Inappropriate Site	3	1.8	1.8	no signal
91	Breast Cancer Metastatic	3	1.8	1.8	no signal
92	Neoplasm Malignant	18	1.7	1.7	no signal
93	Serotonin Syndrome	5	1.7	1.7	no signal
94	Premature Delivery	4	1.6	1.6	no signal
95	Schizophrenia	3	1.6	1.6	no signal
96	Wrong Technique In Product Usage Process	45	1.4	1.4	no signal
97	Skin Irritation	10	1.4	1.4	no signal
98	Drug Effect Incomplete	8	1.4	1.4	no signal
99	Emotional Distress	25	1.3	1.3	no signal
100	Drug Effective For Unapproved Indication	6	1.3	1.3	no signal
101	Product Quality Issue	27	1.3	1.3	no signal
102	Drug Administration Error	6	1.2	1.2	no signal
103	Product Complaint	3	0.8	0.8	no signal
104	Pancreatic Carcinoma	3	0.7	0.7	no signal
105	Drug Dependence	9	0.4	0.4	no signal