OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Cefotaxime

205 flagged reaction(s) · 6,200 total co-reports · max PRR 46.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Drug Reaction With Eosinophilia And Systemic Symptoms 240 46.5 49.2 signal
2 Toxic Epidermal Necrolysis 129 42.3 43.6 signal
3 Hepatocellular Injury 113 39.3 40.3 signal
4 Clostridium Difficile Colitis 65 30.2 30.6 signal
5 Eosinophilia 95 26.8 27.4 signal
6 Rash Maculo-papular 116 25.8 26.5 signal
7 Hepatic Cytolysis 51 20.5 20.8 signal
8 Agranulocytosis 73 19.4 19.8 signal
9 Toxic Skin Eruption 35 17.0 17.2 signal
10 Cholestasis 60 15.4 15.7 signal
11 Hyperbilirubinaemia 32 15.3 15.4 signal
12 Hypotonia 30 14.7 14.8 signal
13 Disseminated Intravascular Coagulation 42 14.6 14.8 signal
14 Multiple Organ Dysfunction Syndrome 78 13.7 14.0 signal
15 Septic Shock 105 11.9 12.2 signal
16 Brain Oedema 30 11.7 11.7 signal
17 Thrombotic Microangiopathy 23 11.7 11.7 signal
18 Drug Resistance 55 10.5 10.6 signal
19 Encephalopathy 52 10.4 10.5 signal
20 Status Epilepticus 24 10.4 10.5 signal
21 Premature Baby 64 10.4 10.6 signal
22 Transaminases Increased 43 9.5 9.6 signal
23 Stevens-johnson Syndrome 43 9.5 9.6 signal
24 Leukocytosis 33 9.0 9.0 signal
25 Coagulopathy 28 8.3 8.3 signal
26 Posterior Reversible Encephalopathy Syndrome 16 8.3 8.3 signal
27 Electrolyte Imbalance 19 8.1 8.1 signal
28 Generalised Tonic-clonic Seizure 27 8.1 8.1 signal
29 Acute Respiratory Distress Syndrome 29 8.0 8.1 signal
30 Candida Infection 27 7.9 8.0 signal
31 Respiratory Distress 44 7.8 7.9 signal
32 Erythema Multiforme 14 7.4 7.4 signal
33 Tachypnoea 20 7.2 7.3 signal
34 Pancytopenia 77 6.8 6.9 signal
35 Generalised Oedema 17 6.8 6.8 signal
36 Gamma-glutamyltransferase Increased 30 6.6 6.7 signal
37 Lymphopenia 19 6.6 6.7 signal
38 Thrombocytopenia 150 6.6 6.8 signal
39 Electrocardiogram Qt Prolonged 48 6.5 6.6 signal
40 Face Oedema 22 6.4 6.4 signal
41 Acute Kidney Injury 195 6.3 6.5 signal
42 Neutrophil Count Increased 13 6.2 6.2 signal
43 Metabolic Acidosis 40 6.2 6.3 signal
44 Cytomegalovirus Infection 21 6.2 6.2 signal
45 Covid-19 Pneumonia 15 6.2 6.2 signal
46 Petechiae 13 6.1 6.1 signal
47 Altered State Of Consciousness 26 5.9 6.0 signal
48 Cyanosis 19 5.9 5.9 signal
49 Pneumocystis Jirovecii Pneumonia 12 5.9 5.9 signal
50 Pulmonary Hypertension 25 5.9 5.9 signal
51 Leukopenia 59 5.8 5.9 signal
52 Bone Marrow Failure 24 5.8 5.8 signal
53 Hepatitis 30 5.8 5.8 signal
54 Sepsis 129 5.7 5.8 signal
55 Oral Candidiasis 15 5.7 5.7 signal
56 Anaphylactic Shock 29 5.6 5.6 signal
57 Hepatomegaly 11 5.5 5.5 signal
58 Neutropenia 149 5.4 5.6 signal
59 Multi-organ Failure 19 5.3 5.3 signal
60 Drug Eruption 19 5.3 5.3 signal
61 Abscess 17 5.2 5.2 signal
62 Circulatory Collapse 18 5.2 5.2 signal
63 Shock 24 5.2 5.2 signal
64 Cardiogenic Shock 15 5.2 5.2 signal
65 Bronchospasm 15 5.1 5.2 signal
66 Hypokalaemia 48 5.1 5.2 signal
67 C-reactive Protein Increased 38 5.1 5.2 signal
68 Hyperkalaemia 36 5.1 5.1 signal
69 Sudden Death 11 5.0 5.1 signal
70 Lactic Acidosis 33 5.0 5.1 signal
71 Renal Tubular Necrosis 10 5.0 5.0 signal
72 Myoclonus 12 4.9 4.9 signal
73 Nephropathy Toxic 11 4.8 4.9 signal
74 Pancreatitis Acute 22 4.8 4.9 signal
75 Pulmonary Congestion 13 4.8 4.8 signal
76 Hypoxia 34 4.8 4.8 signal
77 Pneumothorax 15 4.6 4.7 signal
78 Respiratory Failure 69 4.6 4.7 signal
79 Acute Respiratory Failure 18 4.6 4.6 signal
80 Foetal Exposure During Pregnancy 76 4.6 4.7 signal
81 Blood Creatinine Increased 61 4.6 4.6 signal
82 Body Temperature Increased 19 4.6 4.6 signal
83 Hepatic Failure 28 4.5 4.6 signal
84 Ataxia 11 4.5 4.5 signal
85 Neurotoxicity 16 4.5 4.5 signal
86 Muscle Rigidity 11 4.5 4.5 signal
87 Rhabdomyolysis 38 4.5 4.5 signal
88 Blood Alkaline Phosphatase Increased 22 4.3 4.4 signal
89 Peritonitis 18 4.3 4.3 signal
90 Hepatic Encephalopathy 8 4.2 4.2 signal
91 Tubulointerstitial Nephritis 16 4.2 4.2 signal
92 Diarrhoea Haemorrhagic 8 4.2 4.2 signal
93 Bacteraemia 10 4.2 4.2 signal
94 Proteinuria 16 4.2 4.2 signal
95 Platelet Count Increased 11 4.1 4.1 signal
96 Neuroleptic Malignant Syndrome 10 4.1 4.1 signal
97 Liver Disorder 37 4.1 4.1 signal
98 Respiratory Depression 10 4.0 4.0 signal
99 Pyrexia 280 4.0 4.2 signal
100 Lymphadenopathy 28 3.9 3.9 signal
101 Clostridium Difficile Infection 17 3.8 3.9 signal
102 Ventricular Tachycardia 13 3.8 3.9 signal
103 Skin Reaction 11 3.8 3.8 signal
104 Blood Urea Increased 13 3.8 3.8 signal
105 Oxygen Saturation Decreased 43 3.8 3.8 signal
106 Pallor 21 3.8 3.8 signal
107 International Normalised Ratio Increased 22 3.7 3.8 signal
108 Hemiparesis 13 3.7 3.7 signal
109 Urosepsis 7 3.7 3.7 signal
110 Bradycardia 40 3.7 3.7 signal
111 Premature Delivery 12 3.7 3.7 signal
112 Renal Failure Acute 32 3.6 3.7 signal
113 Aspiration 8 3.6 3.6 signal
114 Rash Erythematous 34 3.6 3.6 signal
115 Red Blood Cell Sedimentation Rate Increased 8 3.5 3.5 signal
116 Bacterial Infection 13 3.4 3.4 signal
117 Brain Injury 7 3.4 3.4 signal
118 Blood Lactate Dehydrogenase Increased 11 3.4 3.4 signal
119 Cardio-respiratory Arrest 29 3.4 3.4 signal
120 Rash Generalised 18 3.4 3.4 signal
121 Blood Creatine Phosphokinase Increased 20 3.4 3.4 signal
122 Pneumonia Aspiration 17 3.3 3.4 signal
123 Renal Failure 91 3.3 3.4 signal
124 Cerebral Haemorrhage 24 3.3 3.3 signal
125 Rash Papular 15 3.3 3.3 signal
126 Tachycardia 59 3.3 3.3 signal
127 Drug Interaction 105 3.2 3.3 signal
128 Drug-induced Liver Injury 20 3.2 3.2 signal
129 Cardiac Arrest 53 3.1 3.2 signal
130 Coma 30 3.1 3.1 signal
131 Anaemia 120 3.1 3.1 signal
132 Aphasia 19 3.1 3.1 signal
133 Subdural Haematoma 9 3.1 3.1 signal
134 Intestinal Perforation 7 3.1 3.1 signal
135 Aspartate Aminotransferase Increased 33 3.0 3.1 signal
136 Gastroenteritis 9 3.0 3.0 signal
137 Myocardial Ischaemia 7 3.0 3.0 signal
138 Drug Level Increased 10 3.0 3.0 signal
139 Hepatic Function Abnormal 22 2.9 2.9 signal
140 Pneumonitis 16 2.9 2.9 signal
141 Hypothermia 6 2.9 2.9 signal
142 Device Related Infection 9 2.9 2.9 signal
143 Exposure During Pregnancy 36 2.8 2.9 signal
144 Hypoglycaemia 28 2.8 2.8 signal
145 Ventricular Extrasystoles 6 2.8 2.8 signal
146 Mucosal Inflammation 15 2.8 2.8 signal
147 Renal Impairment 48 2.8 2.8 signal
148 White Blood Cell Count Increased 22 2.8 2.8 signal
149 Colitis 21 2.7 2.7 signal
150 Lethargy 32 2.7 2.7 signal
151 Drug Ineffective For Unapproved Indication 30 2.6 2.7 signal
152 Liver Injury 13 2.6 2.6 signal
153 Alanine Aminotransferase Increased 33 2.6 2.6 signal
154 Haemoptysis 15 2.6 2.6 signal
155 Pulmonary Oedema 24 2.6 2.6 signal
156 Grand Mal Convulsion 5 2.6 2.6 no signal
157 Respiratory Disorder 16 2.6 2.6 signal
158 Pulmonary Fibrosis 10 2.6 2.6 signal
159 Sinus Bradycardia 5 2.5 2.5 no signal
160 Acute Hepatic Failure 7 2.5 2.5 signal
161 Vasculitis 6 2.5 2.5 signal
162 Dystonia 10 2.5 2.5 signal
163 Blood Iron Decreased 6 2.5 2.5 no signal
164 Febrile Neutropenia 33 2.4 2.5 signal
165 Rash Macular 17 2.4 2.4 signal
166 Hypercalcaemia 6 2.4 2.4 no signal
167 Liver Function Test Abnormal 14 2.3 2.4 signal
168 Hallucination, Visual 10 2.3 2.3 signal
169 Interstitial Lung Disease 23 2.3 2.3 signal
170 Jaundice 12 2.2 2.2 signal
171 Osteomyelitis 8 2.2 2.2 no signal
172 Gingival Bleeding 6 2.2 2.2 no signal
173 Cardiac Failure 34 2.1 2.1 signal
174 Product Prescribing Error 10 2.1 2.1 signal
175 Nervous System Disorder 13 2.0 2.0 signal
176 Fluid Overload 6 2.0 2.0 no signal
177 Drug Withdrawal Syndrome Neonatal 6 2.0 2.0 no signal
178 Product Administration Error 8 2.0 2.0 no signal
179 Contraindicated Product Administered 12 2.0 2.0 no signal
180 Maternal Exposure During Pregnancy 35 1.9 2.0 no signal
181 Drug Level Decreased 4 1.9 1.9 no signal
182 Mydriasis 5 1.9 1.9 no signal
183 Transfusion 4 1.9 1.9 no signal
184 Gastrointestinal Haemorrhage 31 1.8 1.8 no signal
185 Serotonin Syndrome 7 1.8 1.8 no signal
186 Dialysis 5 1.7 1.7 no signal
187 Pulmonary Arterial Hypertension 5 1.7 1.7 no signal
188 Caesarean Section 4 1.7 1.7 no signal
189 Ischaemic Stroke 6 1.6 1.6 no signal
190 Haemorrhage Intracranial 5 1.6 1.6 no signal
191 Accidental Overdose 12 1.6 1.6 no signal
192 Angioedema 14 1.6 1.6 no signal
193 Convulsion 18 1.5 1.5 no signal
194 Drug Toxicity 4 1.4 1.4 no signal
195 Metrorrhagia 5 1.4 1.4 no signal
196 Cytokine Release Syndrome 5 1.3 1.3 no signal
197 Toxicity To Various Agents 43 1.3 1.3 no signal
198 Myelosuppression 8 1.2 1.2 no signal
199 Tuberculosis 3 1.1 1.1 no signal
200 Injection Site Haematoma 3 1.0 1.0 no signal
201 Drug Exposure During Pregnancy 6 0.9 0.9 no signal
202 Palmar-plantar Erythrodysaesthesia Syndrome 4 0.8 0.8 no signal
203 Drug Effective For Unapproved Indication 4 0.7 0.7 no signal
204 Extrapyramidal Disorder 3 0.6 0.6 no signal
205 Incorrect Route Of Drug Administration 4 0.5 0.5 no signal