Drug

Ceritinib

68 flagged reaction(s) · 2,863 total co-reports · max PRR 120.0

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Metastases To Central Nervous System	172	120.0	129.3	signal
2	Neoplasm	55	42.3	43.3	signal
3	Malignant Neoplasm Progression	427	37.1	45.0	signal
4	Metastases To Liver	51	25.7	26.3	signal
5	Metastases To Bone	45	24.3	24.8	signal
6	Metastases To Lung	28	21.4	21.7	signal
7	Brain Neoplasm	22	21.2	21.3	signal
8	Neoplasm Progression	66	16.6	17.1	signal
9	Central Nervous System Lesion	26	16.6	16.8	signal
10	Pericarditis	29	15.4	15.5	signal
11	Transaminases Increased	37	14.7	14.9	signal
12	Hepatic Function Abnormal	61	14.5	14.9	signal
13	Blood Alkaline Phosphatase Increased	40	14.2	14.4	signal
14	Lung Neoplasm Malignant	66	14.1	14.5	signal
15	Drug Resistance	41	14.1	14.3	signal
16	Pericardial Effusion	36	13.8	14.0	signal
17	Pneumonitis	37	12.1	12.3	signal
18	Hepatotoxicity	30	11.9	12.1	signal
19	Brain Oedema	15	10.5	10.5	signal
20	Aspartate Aminotransferase Increased	61	10.1	10.4	signal
21	Therapy Partial Responder	16	9.4	9.4	signal
22	Alanine Aminotransferase Increased	64	9.2	9.4	signal
23	Gamma-glutamyltransferase Increased	22	8.8	8.8	signal
24	Disease Progression	112	8.4	8.7	signal
25	Atelectasis	9	8.2	8.2	signal
26	Liver Disorder	40	8.0	8.1	signal
27	Pleural Effusion	54	7.8	8.0	signal
28	C-reactive Protein Increased	30	7.3	7.4	signal
29	Cerebral Infarction	20	7.2	7.3	signal
30	Generalised Oedema	10	7.2	7.2	signal
31	Blood Creatinine Increased	53	7.1	7.3	signal
32	Pulmonary Mass	12	7.1	7.2	signal
33	Intestinal Perforation	9	7.1	7.1	signal
34	Appendicitis	7	6.6	6.7	signal
35	Hypercholesterolaemia	7	6.5	6.5	signal
36	Liver Function Test Increased	15	6.2	6.2	signal
37	Diarrhoea	426	5.8	6.9	signal
38	Hepatitis	16	5.5	5.5	signal
39	Hepatic Enzyme Increased	42	5.5	5.5	signal
40	White Blood Cell Count Increased	23	5.3	5.3	signal
41	Neutrophil Count Increased	6	5.1	5.2	signal
42	Hepatic Failure	17	5.0	5.0	signal
43	Photosensitivity Reaction	9	4.8	4.8	signal
44	Nerve Compression	5	4.8	4.8	signal
45	Haemoptysis	15	4.7	4.8	signal
46	Hepatic Encephalopathy	5	4.7	4.7	signal
47	Sinus Bradycardia	5	4.6	4.6	signal
48	Eating Disorder	11	4.5	4.6	signal
49	Cholecystitis	6	4.5	4.5	signal
50	Blood Lactate Dehydrogenase Increased	8	4.4	4.4	signal
51	Interstitial Lung Disease	24	4.4	4.4	signal
52	Hyperglycaemia	18	4.4	4.4	signal
53	Hepatocellular Injury	7	4.3	4.4	signal
54	Hyperbilirubinaemia	5	4.3	4.3	signal
55	Electrocardiogram Qt Prolonged	17	4.2	4.2	signal
56	Platelet Count Increased	6	4.1	4.1	signal
57	Epilepsy	14	4.0	4.1	signal
58	Liver Injury	11	4.0	4.0	signal
59	Nephropathy Toxic	5	4.0	4.0	signal
60	Liver Function Test Abnormal	13	3.9	3.9	signal
61	Cholestasis	7	3.2	3.2	signal
62	Cerebral Haemorrhage	13	3.2	3.2	signal
63	Death	281	2.9	3.1	signal
64	Acute Hepatic Failure	4	2.6	2.6	no signal
65	Osteonecrosis Of Jaw	7	2.5	2.5	signal
66	Pulmonary Arterial Hypertension	4	2.4	2.4	no signal
67	Palmar-plantar Erythrodysaesthesia Syndrome	5	1.9	1.9	no signal
68	Intentional Self-injury	3	1.3	1.3	no signal