OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Cinacalcet

178 flagged reaction(s) · 4,512 total co-reports · max PRR 69.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Hypercalcaemia 189 69.8 72.7 signal
2 Hypocalcaemia 273 65.8 69.8 signal
3 End Stage Renal Disease 87 21.3 21.7 signal
4 Hypomagnesaemia 64 20.8 21.1 signal
5 Vitamin D Deficiency 28 12.9 13.0 signal
6 Peritonitis Bacterial 27 12.1 12.1 signal
7 Premature Delivery 38 10.7 10.8 signal
8 Hyperkalaemia 58 7.5 7.5 signal
9 Dialysis 23 7.3 7.3 signal
10 Therapy Non-responder 71 7.2 7.2 signal
11 Fluid Overload 23 7.0 7.0 signal
12 Peritonitis 32 6.9 7.0 signal
13 Drug Effective For Unapproved Indication 45 6.9 7.0 signal
14 Myoclonus 18 6.8 6.8 signal
15 Premature Baby 45 6.7 6.7 signal
16 Blood Calcium Decreased 16 6.4 6.4 signal
17 Gastroenteritis 20 6.2 6.2 signal
18 Fracture 24 5.7 5.7 signal
19 Cardiovascular Disorder 32 5.6 5.6 signal
20 Ileus 15 5.5 5.5 signal
21 Chronic Kidney Disease 92 5.4 5.5 signal
22 Malnutrition 13 5.3 5.3 signal
23 Spinal Fracture 23 5.2 5.2 signal
24 Therapy Partial Responder 17 5.1 5.1 signal
25 Acute Myocardial Infarction 33 5.0 5.0 signal
26 Gastric Ulcer 21 5.0 5.0 signal
27 Hypertensive Crisis 12 4.8 4.8 signal
28 Nephropathy 10 4.8 4.8 signal
29 Exposure During Pregnancy 66 4.8 4.8 signal
30 Device Related Infection 16 4.7 4.7 signal
31 Renal Tubular Necrosis 10 4.6 4.6 signal
32 Acute Kidney Injury 150 4.4 4.5 signal
33 Nephrolithiasis 45 4.4 4.4 signal
34 Myocardial Ischaemia 11 4.3 4.3 signal
35 Multiple Organ Dysfunction Syndrome 26 4.2 4.2 signal
36 Sinus Bradycardia 9 4.2 4.2 signal
37 Ataxia 11 4.1 4.2 signal
38 Maternal Exposure During Pregnancy 81 4.1 4.2 signal
39 Osteopenia 14 4.1 4.1 signal
40 Electrocardiogram Qt Prolonged 33 4.1 4.1 signal
41 Bone Density Decreased 29 4.1 4.1 signal
42 Sepsis 100 4.0 4.1 signal
43 Urosepsis 8 3.9 3.9 signal
44 Metastases To Lung 10 3.9 3.9 signal
45 Neurotoxicity 15 3.9 3.9 signal
46 Arteriosclerosis 8 3.8 3.8 signal
47 Ventricular Tachycardia 14 3.8 3.8 signal
48 Posterior Reversible Encephalopathy Syndrome 8 3.8 3.8 signal
49 Treatment Noncompliance 45 3.7 3.7 signal
50 Drug Ineffective For Unapproved Indication 46 3.7 3.7 signal
51 International Normalised Ratio Increased 23 3.6 3.6 signal
52 Encephalopathy 19 3.5 3.5 signal
53 Renal Impairment 64 3.4 3.5 signal
54 Blood Alkaline Phosphatase Increased 19 3.4 3.4 signal
55 Clostridium Difficile Colitis 8 3.4 3.4 signal
56 Renal Failure 99 3.3 3.4 signal
57 Supraventricular Tachycardia 7 3.3 3.3 signal
58 Rib Fracture 15 3.3 3.3 signal
59 Metabolic Acidosis 23 3.3 3.3 signal
60 Foetal Exposure During Pregnancy 59 3.3 3.3 signal
61 Ventricular Fibrillation 8 3.2 3.2 signal
62 Ascites 21 3.2 3.2 signal
63 Cardiogenic Shock 10 3.1 3.1 signal
64 Angina Pectoris 20 3.1 3.1 signal
65 Cardio-respiratory Arrest 29 3.1 3.1 signal
66 Melaena 15 3.1 3.1 signal
67 Blood Potassium Increased 11 3.0 3.0 signal
68 Rectal Haemorrhage 28 2.9 2.9 signal
69 Tendon Rupture 8 2.9 2.9 signal
70 Drug Effect Less Than Expected 9 2.9 2.9 signal
71 Osteoporosis 26 2.8 2.8 signal
72 Intestinal Perforation 7 2.8 2.8 signal
73 Drug Resistance 16 2.8 2.8 signal
74 Mitral Valve Incompetence 7 2.8 2.8 signal
75 Back Disorder 10 2.7 2.8 signal
76 Metastases To Bone 10 2.7 2.7 signal
77 Cholelithiasis 20 2.7 2.7 signal
78 Electrolyte Imbalance 7 2.7 2.7 signal
79 Osteomyelitis 11 2.7 2.7 signal
80 Cytomegalovirus Infection 10 2.7 2.7 signal
81 Pneumocystis Jirovecii Pneumonia 6 2.7 2.7 signal
82 Hospitalisation 91 2.7 2.7 signal
83 Blood Urea Increased 10 2.7 2.7 signal
84 Upper Gastrointestinal Haemorrhage 10 2.7 2.7 signal
85 Coronary Artery Disease 18 2.6 2.7 signal
86 Inappropriate Antidiuretic Hormone Secretion 6 2.6 2.6 signal
87 Tubulointerstitial Nephritis 11 2.6 2.6 signal
88 Neutrophil Count Increased 6 2.6 2.6 signal
89 Unresponsive To Stimuli 15 2.6 2.6 signal
90 Hyperbilirubinaemia 6 2.6 2.6 signal
91 Skin Ulcer 15 2.6 2.6 signal
92 Gastrointestinal Disorder 51 2.6 2.6 signal
93 Staphylococcal Infection 19 2.6 2.6 signal
94 Gastritis 15 2.6 2.6 signal
95 Blood Creatinine Increased 37 2.5 2.5 signal
96 Sudden Death 6 2.5 2.5 signal
97 Hip Fracture 18 2.5 2.5 signal
98 Altered State Of Consciousness 12 2.5 2.5 signal
99 Cardiac Arrest 46 2.5 2.5 signal
100 Wound Infection 6 2.5 2.5 no signal
101 Cardiac Failure 44 2.5 2.5 signal
102 Arrhythmia 26 2.5 2.5 signal
103 Transaminases Increased 12 2.4 2.4 signal
104 Mental Status Changes 15 2.4 2.4 signal
105 Pancytopenia 30 2.4 2.4 signal
106 Hypoglycaemia 26 2.4 2.4 signal
107 Abortion Induced 5 2.4 2.4 no signal
108 Rebound Effect 6 2.4 2.4 no signal
109 Gastrointestinal Haemorrhage 44 2.3 2.4 signal
110 Paranoia 9 2.3 2.3 signal
111 Diverticulitis 14 2.3 2.3 signal
112 Death 436 2.3 2.4 signal
113 Polyneuropathy 6 2.3 2.3 no signal
114 Muscle Rigidity 6 2.3 2.3 no signal
115 Renal Injury 15 2.2 2.2 signal
116 Hypotonia 5 2.2 2.2 no signal
117 Glomerular Filtration Rate Decreased 6 2.2 2.2 no signal
118 Restless Legs Syndrome 9 2.2 2.2 signal
119 Pancreatitis 26 2.2 2.2 signal
120 Hepatic Cytolysis 6 2.2 2.2 no signal
121 Subarachnoid Haemorrhage 5 2.2 2.2 no signal
122 Mania 8 2.2 2.2 signal
123 Muscle Atrophy 6 2.1 2.1 no signal
124 Interstitial Lung Disease 23 2.1 2.1 signal
125 Body Height Decreased 5 2.1 2.1 no signal
126 Kidney Infection 9 2.1 2.1 no signal
127 Eosinophilia 8 2.1 2.1 no signal
128 Economic Problem 7 2.0 2.0 no signal
129 Anhedonia 12 2.0 2.0 signal
130 Treatment Failure 37 2.0 2.0 signal
131 Cerebral Infarction 11 2.0 2.0 signal
132 Quality Of Life Decreased 6 2.0 2.0 no signal
133 Therapy Interrupted 30 2.0 2.0 no signal
134 Gastric Haemorrhage 5 1.9 1.9 no signal
135 Post Procedural Haemorrhage 5 1.9 1.9 no signal
136 Splenomegaly 5 1.9 1.9 no signal
137 Rash Pruritic 23 1.9 1.9 no signal
138 Drug Level Increased 7 1.9 1.9 no signal
139 Leukopenia 21 1.9 1.9 no signal
140 Covid-19 Pneumonia 5 1.9 1.9 no signal
141 Lower Limb Fracture 8 1.9 1.9 no signal
142 Blood Pressure Fluctuation 10 1.9 1.9 no signal
143 Circulatory Collapse 7 1.8 1.8 no signal
144 Disease Progression 46 1.7 1.8 no signal
145 Poor Venous Access 4 1.7 1.7 no signal
146 Agranulocytosis 7 1.7 1.7 no signal
147 Throat Tightness 10 1.7 1.7 no signal
148 Cholestasis 7 1.6 1.6 no signal
149 Akathisia 5 1.6 1.6 no signal
150 Lymphopenia 5 1.6 1.6 no signal
151 Upper Limb Fracture 7 1.6 1.6 no signal
152 Caesarean Section 4 1.5 1.5 no signal
153 Convulsion 19 1.5 1.5 no signal
154 Delusion 5 1.4 1.4 no signal
155 Femur Fracture 10 1.4 1.4 no signal
156 Cardiac Failure Congestive 26 1.4 1.4 no signal
157 Metastases To Central Nervous System 4 1.4 1.4 no signal
158 Dystonia 6 1.4 1.4 no signal
159 Adverse Reaction 4 1.4 1.4 no signal
160 Angioedema 13 1.3 1.3 no signal
161 Cerebrovascular Accident 50 1.3 1.3 no signal
162 Bone Marrow Failure 6 1.3 1.3 no signal
163 Device Occlusion 4 1.3 1.3 no signal
164 Pulmonary Arterial Hypertension 4 1.2 1.2 no signal
165 Product Availability Issue 6 1.2 1.2 no signal
166 Myocardial Infarction 46 1.2 1.2 no signal
167 Pain Of Skin 7 1.2 1.2 no signal
168 Osteonecrosis 8 1.1 1.1 no signal
169 Neoplasm Malignant 16 1.1 1.1 no signal
170 Intraocular Pressure Increased 3 1.0 1.0 no signal
171 Skin Cancer 5 1.0 1.0 no signal
172 Blood Glucose Decreased 11 1.0 1.0 no signal
173 Osteonecrosis Of Jaw 5 0.9 0.9 no signal
174 Sickle Cell Anaemia With Crisis 3 0.9 0.9 no signal
175 Tardive Dyskinesia 5 0.8 0.8 no signal
176 Gastric Cancer 4 0.7 0.7 no signal
177 Myelosuppression 5 0.7 0.7 no signal
178 Renal Cancer 6 0.6 0.6 no signal