Drug

Clonidine Transdermal System

48 flagged reaction(s) · 2,218 total co-reports · max PRR 155.4

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Application Site Pruritus	343	155.4	186.0	signal
2	Application Site Rash	195	145.1	160.1	signal
3	Application Site Erythema	301	117.1	136.9	signal
4	Application Site Irritation	120	98.6	104.6	signal
5	Product Adhesion Issue	164	47.0	51.0	signal
6	Application Site Pain	81	37.4	38.9	signal
7	Blood Pressure Increased	251	16.6	18.8	signal
8	Dermatitis Contact	16	14.3	14.4	signal
9	Blood Pressure Fluctuation	30	12.6	12.8	signal
10	Product Packaging Quantity Issue	11	10.2	10.3	signal
11	Blood Pressure Systolic Increased	18	9.3	9.4	signal
12	Blood Pressure Abnormal	17	8.7	8.8	signal
13	Scar	14	8.3	8.3	signal
14	Sinus Bradycardia	7	7.3	7.3	signal
15	Drug Effect Decreased	37	6.9	7.0	signal
16	Hypertension	143	6.8	7.3	signal
17	Anorexia	8	6.2	6.2	signal
18	Product Quality Issue	82	6.2	6.4	signal
19	Blood Pressure Decreased	35	5.3	5.4	signal
20	Drug Dispensing Error	8	5.2	5.2	signal
21	Pharmaceutical Product Complaint	13	5.0	5.0	signal
22	Dermatitis Allergic	6	4.9	4.9	signal
23	Wrong Technique In Product Usage Process	95	4.8	4.9	signal
24	Medication Error	26	4.7	4.8	signal
25	Heart Rate Decreased	16	4.6	4.6	signal
26	Scab	5	4.5	4.5	signal
27	Skin Irritation	20	4.4	4.4	signal
28	Renal Failure Acute	18	4.2	4.3	signal
29	Heart Rate Irregular	9	4.0	4.0	signal
30	Hypothermia	4	4.0	4.0	signal
31	Sedation	10	3.9	3.9	signal
32	Hypertensive Crisis	4	3.6	3.6	signal
33	Skin Reaction	5	3.6	3.6	signal
34	Rebound Effect	4	3.6	3.6	signal
35	Product Substitution Issue	17	3.0	3.0	signal
36	Neuroleptic Malignant Syndrome	3	2.6	2.6	no signal
37	Product Physical Issue	5	2.5	2.5	no signal
38	Withdrawal Syndrome	10	2.4	2.4	signal
39	Wrong Technique In Drug Usage Process	8	2.2	2.2	signal
40	Circumstance Or Information Capable Of Leading To Medication Error	7	2.1	2.1	no signal
41	Drug Administration Error	6	2.0	2.0	no signal
42	Incorrect Dose Administered By Device	4	1.6	1.6	no signal
43	Skin Burning Sensation	11	1.6	1.6	no signal
44	Completed Suicide	13	1.6	1.6	no signal
45	Tardive Dyskinesia	4	1.4	1.4	no signal
46	Extrapyramidal Disorder	3	1.2	1.2	no signal
47	Incorrect Route Of Drug Administration	4	1.1	1.1	no signal
48	Drug Withdrawal Syndrome	7	0.8	0.8	no signal