Drug

Collagenase Santyl

36 flagged reaction(s) · 986 total co-reports · max PRR 64.5

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Application Site Pain	109	64.5	69.1	signal
2	Wound Infection	46	55.1	56.7	signal
3	Wound	55	25.7	26.6	signal
4	Impaired Healing	60	23.7	24.6	signal
5	Osteomyelitis	21	15.1	15.3	signal
6	Skin Ulcer	29	14.6	14.8	signal
7	End Stage Renal Disease	20	14.1	14.3	signal
8	Application Site Erythema	26	12.8	13.0	signal
9	Renal Tubular Necrosis	9	11.9	11.9	signal
10	Hospice Care	9	11.9	11.9	signal
11	Application Site Irritation	9	9.4	9.4	signal
12	Scab	8	9.2	9.2	signal
13	Chronic Kidney Disease	52	8.8	9.1	signal
14	Ulcer	10	8.1	8.2	signal
15	Drug Administered At Inappropriate Site	6	7.3	7.3	signal
16	Cellulitis	27	6.9	7.0	signal
17	Localised Infection	12	6.4	6.5	signal
18	Nephropathy	4	5.5	5.5	signal
19	Product Administration Error	8	5.2	5.2	signal
20	Death	341	5.1	6.2	signal
21	Scratch	4	5.0	5.0	signal
22	Burning Sensation	27	5.0	5.1	signal
23	Renal Injury	11	4.8	4.8	signal
24	Expired Product Administered	12	4.7	4.7	signal
25	Increased Tendency To Bruise	3	4.2	4.2	signal
26	Leukaemia	3	4.1	4.1	signal
27	Skin Exfoliation	24	3.7	3.8	signal
28	Dialysis	4	3.6	3.7	signal
29	Application Site Pruritus	6	3.4	3.4	signal
30	Blood Count Abnormal	4	3.4	3.4	signal
31	Muscle Spasticity	3	3.1	3.1	no signal
32	Product Availability Issue	5	2.9	2.9	signal
33	Product Administered At Inappropriate Site	4	2.9	2.9	no signal
34	Drug Effect Incomplete	8	2.8	2.8	signal
35	Incorrect Drug Administration Duration	4	1.8	1.8	no signal
36	Exposure Via Skin Contact	3	1.7	1.7	no signal