OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Dexmethylphenidate Hydrochloride

199 flagged reaction(s) · 6,395 total co-reports · max PRR 21.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Abnormal Behaviour 168 21.1 21.9 signal
2 Psychomotor Hyperactivity 62 18.6 18.9 signal
3 Disturbance In Attention 158 14.6 15.1 signal
4 Anger 98 14.4 14.7 signal
5 Aggression 144 14.3 14.8 signal
6 Paranoia 47 13.6 13.7 signal
7 Mood Swings 66 10.3 10.5 signal
8 Product Physical Issue 40 10.0 10.1 signal
9 Brain Injury 20 9.9 10.0 signal
10 Crying 72 9.9 10.0 signal
11 Irritability 118 9.8 10.0 signal
12 Emotional Disorder 60 9.7 9.8 signal
13 Product Substitution Issue 108 9.4 9.6 signal
14 Hypertensive Crisis 20 8.9 9.0 signal
15 Product Availability Issue 39 8.7 8.8 signal
16 Gynaecomastia 53 8.5 8.5 signal
17 Bipolar Disorder 18 8.2 8.2 signal
18 Mydriasis 18 7.0 7.0 signal
19 Initial Insomnia 14 6.9 6.9 signal
20 Pharyngitis Streptococcal 14 6.5 6.5 signal
21 Mood Altered 35 6.4 6.5 signal
22 Amenorrhoea 21 6.3 6.3 signal
23 Feeling Jittery 24 6.3 6.3 signal
24 Personality Change 11 5.9 5.9 signal
25 Muscle Twitching 27 5.8 5.9 signal
26 Drug Dispensing Error 18 5.8 5.8 signal
27 Suicidal Ideation 105 5.7 5.8 signal
28 Insurance Issue 17 5.7 5.7 signal
29 Drug Prescribing Error 22 5.6 5.7 signal
30 Drug Administered At Inappropriate Site 12 5.6 5.6 signal
31 Withdrawal Syndrome 47 5.6 5.6 signal
32 Hallucination, Auditory 17 5.3 5.3 signal
33 Wrong Technique In Drug Usage Process 39 5.3 5.3 signal
34 Affect Lability 10 5.2 5.2 signal
35 Psychotic Disorder 30 5.1 5.1 signal
36 Tardive Dyskinesia 28 4.9 4.9 signal
37 Treatment Failure 79 4.8 4.9 signal
38 Agitation 69 4.7 4.7 signal
39 Prescribed Overdose 18 4.6 4.7 signal
40 Depressed Mood 48 4.5 4.6 signal
41 Hypophagia 23 4.5 4.5 signal
42 Application Site Irritation 11 4.4 4.4 signal
43 Drug Effect Less Than Expected 12 4.2 4.3 signal
44 Retching 18 4.2 4.2 signal
45 Product Use Complaint 13 4.2 4.2 signal
46 Sleep Apnoea Syndrome 16 4.2 4.2 signal
47 Liver Injury 20 4.1 4.1 signal
48 Product Packaging Quantity Issue 9 4.1 4.1 signal
49 Coeliac Disease 8 4.1 4.1 signal
50 Fear 22 4.0 4.1 signal
51 Hallucination, Visual 17 4.0 4.1 signal
52 Middle Insomnia 15 4.0 4.0 signal
53 Abnormal Weight Gain 10 4.0 4.0 signal
54 Eating Disorder 17 4.0 4.0 signal
55 Micturition Urgency 9 4.0 4.0 signal
56 Convulsion 46 4.0 4.0 signal
57 Product Quality Issue 102 3.8 3.8 signal
58 Obesity 12 3.8 3.8 signal
59 Grand Mal Convulsion 7 3.7 3.7 signal
60 Hallucination 56 3.7 3.8 signal
61 Supraventricular Tachycardia 7 3.7 3.7 signal
62 Mania 12 3.6 3.6 signal
63 Application Site Erythema 19 3.6 3.6 signal
64 Inability To Afford Medication 7 3.5 3.6 signal
65 Application Site Pruritus 16 3.5 3.5 signal
66 Thinking Abnormal 13 3.5 3.5 signal
67 Feeling Abnormal 166 3.4 3.5 signal
68 Drug Level Decreased 7 3.4 3.4 signal
69 Anxiety 195 3.4 3.5 signal
70 Decreased Appetite 158 3.4 3.5 signal
71 Restlessness 25 3.4 3.4 signal
72 Euphoric Mood 7 3.4 3.4 signal
73 Ear Infection 18 3.4 3.4 signal
74 Hunger 9 3.3 3.3 signal
75 Dystonia 13 3.3 3.3 signal
76 Gastroenteritis Viral 12 3.3 3.3 signal
77 Peripheral Coldness 9 3.3 3.3 signal
78 Sedation 17 3.3 3.3 signal
79 Lethargy 37 3.2 3.2 signal
80 Drug Effect Decreased 35 3.2 3.2 signal
81 Increased Appetite 12 3.2 3.2 signal
82 Cyanosis 10 3.2 3.2 signal
83 Cold Sweat 11 3.1 3.1 signal
84 Therapy Change 6 3.1 3.1 signal
85 Device Mechanical Issue 8 3.1 3.1 signal
86 Rebound Effect 7 3.1 3.1 signal
87 Brain Fog 9 3.1 3.1 signal
88 Depression 138 3.0 3.1 signal
89 Therapeutic Response Unexpected 27 3.0 3.0 signal
90 Therapeutic Response Shortened 19 3.0 3.0 signal
91 Intentional Self-injury 12 3.0 3.0 signal
92 Dyskinesia 24 3.0 3.0 signal
93 Nervousness 31 2.9 3.0 signal
94 Heart Rate Increased 58 2.9 2.9 signal
95 Intentional Dose Omission 16 2.9 2.9 signal
96 Somnolence 116 2.9 2.9 signal
97 Drug Ineffective 757 2.9 3.3 signal
98 Palpitations 67 2.9 2.9 signal
99 Thirst 10 2.8 2.8 signal
100 Medication Error 31 2.8 2.8 signal
101 Impaired Quality Of Life 8 2.8 2.8 signal
102 Skin Laceration 6 2.8 2.8 signal
103 Apathy 8 2.7 2.7 signal
104 Panic Attack 20 2.7 2.7 signal
105 Nightmare 19 2.7 2.7 signal
106 Drug Administration Error 17 2.7 2.7 signal
107 Insomnia 143 2.7 2.7 signal
108 Product Taste Abnormal 7 2.6 2.6 signal
109 Therapeutic Product Effect Decreased 23 2.6 2.6 signal
110 Device Breakage 20 2.5 2.5 signal
111 Illness 51 2.5 2.5 signal
112 Hyperhidrosis 65 2.5 2.5 signal
113 Neck Pain 28 2.5 2.5 signal
114 Incorrect Drug Administration Duration 14 2.4 2.5 signal
115 Unevaluable Event 37 2.4 2.5 signal
116 Poor Venous Access 5 2.4 2.4 no signal
117 Swelling Face 31 2.4 2.4 signal
118 Feeling Hot 29 2.4 2.4 signal
119 Serotonin Syndrome 9 2.3 2.3 signal
120 Mental Disorder 20 2.3 2.3 signal
121 Weight Increased 102 2.3 2.3 signal
122 Mental Impairment 11 2.3 2.3 signal
123 Akathisia 6 2.2 2.2 no signal
124 Adverse Drug Reaction 39 2.2 2.2 signal
125 Nerve Compression 4 2.2 2.2 no signal
126 Movement Disorder 14 2.2 2.2 signal
127 Sleep Disorder Due To A General Medical Condition 7 2.2 2.2 no signal
128 Wrong Technique In Product Usage Process 87 2.1 2.2 signal
129 Coordination Abnormal 6 2.1 2.1 no signal
130 Product Prescribing Error 10 2.1 2.1 signal
131 Muscle Rigidity 5 2.1 2.1 no signal
132 Autoimmune Disorder 4 2.1 2.1 no signal
133 Intentional Product Misuse 36 2.1 2.1 signal
134 Product Dispensing Error 9 2.1 2.1 no signal
135 Loss Of Consciousness 53 2.1 2.1 signal
136 No Therapeutic Response 5 2.0 2.0 no signal
137 Body Temperature Decreased 4 2.0 2.0 no signal
138 Migraine 38 2.0 2.0 no signal
139 Drug Dose Omission By Device 30 2.0 2.0 no signal
140 No Adverse Event 69 1.9 2.0 no signal
141 Delusion 6 1.9 1.9 no signal
142 Anorexia 5 1.9 1.9 no signal
143 Dysmenorrhoea 5 1.9 1.9 no signal
144 Product Dose Omission Issue 101 1.8 1.8 no signal
145 Emotional Distress 43 1.8 1.8 no signal
146 Cholecystectomy 4 1.8 1.8 no signal
147 Product Dose Omission 23 1.7 1.7 no signal
148 Sexual Dysfunction 4 1.7 1.7 no signal
149 Schizophrenia 4 1.6 1.6 no signal
150 Product Complaint 8 1.6 1.6 no signal
151 Suicide Attempt 19 1.6 1.6 no signal
152 Knee Operation 3 1.5 1.5 no signal
153 Product Dose Omission In Error 8 1.5 1.5 no signal
154 Therapy Cessation 15 1.5 1.5 no signal
155 Product Odour Abnormal 3 1.4 1.4 no signal
156 Syringe Issue 5 1.4 1.4 no signal
157 Product Adhesion Issue 10 1.4 1.4 no signal
158 Extrapyramidal Disorder 7 1.4 1.4 no signal
159 Eczema 14 1.4 1.4 no signal
160 Extra Dose Administered 11 1.4 1.4 no signal
161 Application Site Pain 6 1.4 1.4 no signal
162 Abnormal Dreams 7 1.3 1.3 no signal
163 Menorrhagia 5 1.3 1.3 no signal
164 Drug Dose Omission 41 1.2 1.2 no signal
165 Muscle Spasticity 3 1.2 1.2 no signal
166 Intentional Drug Misuse 5 1.2 1.2 no signal
167 Complication Associated With Device 3 1.1 1.1 no signal
168 Injection Site Urticaria 5 1.0 1.0 no signal
169 Dermatitis Atopic 10 1.0 1.0 no signal
170 Incorrect Route Of Drug Administration 7 1.0 1.0 no signal
171 Incorrect Dose Administered 43 1.0 1.0 no signal
172 Drug Effect Incomplete 7 0.9 0.9 no signal
173 Pharmaceutical Product Complaint 5 0.9 0.9 no signal
174 Device Leakage 8 0.9 0.9 no signal
175 Menstruation Irregular 5 0.9 0.9 no signal
176 Acne 14 0.9 0.9 no signal
177 Device Issue 16 0.9 0.9 no signal
178 Drug Withdrawal Syndrome 16 0.9 0.9 no signal
179 Inappropriate Schedule Of Drug Administration 13 0.9 0.9 no signal
180 Exposure Via Skin Contact 4 0.9 0.9 no signal
181 Complication Of Device Removal 3 0.9 0.9 no signal
182 Wrong Technique In Device Usage Process 8 0.9 0.9 no signal
183 Needle Issue 5 0.9 0.9 no signal
184 Product Administered At Inappropriate Site 3 0.8 0.8 no signal
185 Injection Site Bruising 13 0.8 0.8 no signal
186 Device Use Error 5 0.7 0.7 no signal
187 Product Preparation Error 3 0.7 0.7 no signal
188 Intentional Overdose 9 0.7 0.7 no signal
189 Skin Burning Sensation 10 0.7 0.7 no signal
190 Device Malfunction 9 0.7 0.7 no signal
191 Injection Site Haemorrhage 10 0.6 0.6 no signal
192 Abortion Spontaneous 5 0.6 0.6 no signal
193 Injection Site Pain 37 0.6 0.6 no signal
194 Accidental Exposure To Product 12 0.6 0.6 no signal
195 Multiple Sclerosis Relapse 8 0.6 0.6 no signal
196 Device Dislocation 5 0.6 0.6 no signal
197 Injection Site Mass 4 0.5 0.5 no signal
198 Drug Dependence 15 0.5 0.5 no signal
199 Device Expulsion 3 0.2 0.2 no signal