OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Dextromethorphan Hydrobromide And Quinidine Sulfate

112 flagged reaction(s) · 3,432 total co-reports · max PRR 60.2
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Inability To Afford Medication 101 60.2 61.9 signal
2 Affect Lability 45 27.1 27.4 signal
3 Therapy Interrupted 161 13.6 14.1 signal
4 Crying 83 13.2 13.5 signal
5 Drug Effective For Unapproved Indication 66 13.1 13.3 signal
6 Therapeutic Response Unexpected 80 10.3 10.5 signal
7 Insurance Issue 26 10.2 10.2 signal
8 Muscle Spasticity 19 8.9 8.9 signal
9 Disease Recurrence 63 7.7 7.8 signal
10 Central Nervous System Lesion 18 7.6 7.6 signal
11 Aggression 63 7.3 7.4 signal
12 Multiple Sclerosis Relapse 81 6.8 6.9 signal
13 Multiple Sclerosis 56 6.8 6.9 signal
14 Lethargy 63 6.4 6.5 signal
15 Dysphagia 101 6.2 6.3 signal
16 Dementia 29 6.0 6.1 signal
17 Therapy Cessation 53 6.0 6.1 signal
18 Hospice Care 10 5.9 5.9 signal
19 Serotonin Syndrome 19 5.8 5.8 signal
20 Hypersomnia 28 5.7 5.7 signal
21 Anger 33 5.6 5.7 signal
22 Delusion 15 5.6 5.6 signal
23 Aphasia 29 5.6 5.6 signal
24 Abnormal Behaviour 37 5.4 5.4 signal
25 Sedation 24 5.3 5.4 signal
26 Agitation 65 5.1 5.2 signal
27 Bedridden 11 4.9 4.9 signal
28 Hallucination, Visual 17 4.7 4.7 signal
29 Product Use In Unapproved Indication 195 4.6 4.8 signal
30 Incontinence 8 4.4 4.4 signal
31 Muscle Rigidity 9 4.4 4.4 signal
32 Hallucination 56 4.3 4.4 signal
33 Activities Of Daily Living Impaired 15 4.3 4.3 signal
34 Dysarthria 28 4.3 4.3 signal
35 Choking 14 4.2 4.2 signal
36 Psychotic Disorder 21 4.1 4.1 signal
37 Bladder Disorder 7 4.1 4.1 signal
38 Gait Inability 23 4.0 4.0 signal
39 Muscle Twitching 16 4.0 4.0 signal
40 Speech Disorder 36 4.0 4.0 signal
41 Hypoaesthesia Oral 10 3.9 3.9 signal
42 Drug Effect Decreased 36 3.8 3.8 signal
43 Feeding Disorder 13 3.8 3.8 signal
44 Seizure 74 3.7 3.8 signal
45 Balance Disorder 54 3.6 3.7 signal
46 Fall 207 3.6 3.8 signal
47 Unresponsive To Stimuli 16 3.6 3.6 signal
48 Micturition Urgency 7 3.6 3.6 signal
49 Electrocardiogram Qt Prolonged 22 3.5 3.6 signal
50 Head Injury 19 3.5 3.5 signal
51 Product Prescribing Issue 12 3.4 3.4 signal
52 Cognitive Disorder 27 3.4 3.4 signal
53 Paranoia 10 3.3 3.4 signal
54 Dyskinesia 23 3.3 3.3 signal
55 Restless Legs Syndrome 10 3.2 3.2 signal
56 Bipolar Disorder 6 3.2 3.2 signal
57 Urinary Retention 18 3.1 3.1 signal
58 Product Use Complaint 8 3.0 3.0 signal
59 Somnolence 103 3.0 3.0 signal
60 Dysstasia 15 3.0 3.0 signal
61 Heart Rate Decreased 18 3.0 3.0 signal
62 Product Use Issue 95 2.9 3.0 signal
63 Gait Disturbance 97 2.9 3.0 signal
64 Loss Of Personal Independence In Daily Activities 24 2.9 2.9 signal
65 Ataxia 6 2.9 2.9 signal
66 Device Occlusion 7 2.9 2.9 signal
67 Prescribed Underdose 10 2.9 2.9 signal
68 Coordination Abnormal 7 2.9 2.9 signal
69 Brain Injury 5 2.9 2.9 signal
70 Motor Dysfunction 5 2.9 2.9 signal
71 Temperature Intolerance 5 2.8 2.8 signal
72 Hypokinesia 7 2.8 2.8 signal
73 Memory Impairment 65 2.7 2.8 signal
74 Emotional Disorder 14 2.6 2.6 signal
75 Sars-cov-2 Test Positive 6 2.6 2.6 signal
76 Mood Swings 14 2.5 2.6 signal
77 Drug Effect Incomplete 16 2.5 2.5 signal
78 Withdrawal Syndrome 17 2.3 2.3 signal
79 Product Availability Issue 9 2.3 2.3 signal
80 Salivary Hypersecretion 4 2.3 2.3 no signal
81 Suicidal Ideation 35 2.2 2.2 signal
82 Depressed Mood 20 2.2 2.2 signal
83 Middle Insomnia 7 2.2 2.2 no signal
84 Mental Impairment 9 2.2 2.2 signal
85 Disturbance In Attention 20 2.1 2.2 signal
86 Mood Altered 10 2.1 2.1 signal
87 Mania 6 2.1 2.1 no signal
88 Abasia 9 2.1 2.1 signal
89 Drug Dose Omission 59 2.0 2.1 signal
90 Impaired Driving Ability 4 2.0 2.0 no signal
91 Unevaluable Event 25 1.9 1.9 no signal
92 Personality Change 3 1.9 1.9 no signal
93 Grand Mal Convulsion 3 1.9 1.9 no signal
94 Product Dose Omission Issue 91 1.9 1.9 no signal
95 Adverse Event 29 1.8 1.8 no signal
96 Hallucination, Auditory 5 1.8 1.8 no signal
97 Product Dose Omission 20 1.8 1.8 no signal
98 Adverse Reaction 4 1.7 1.7 no signal
99 Therapeutic Response Shortened 9 1.6 1.6 no signal
100 Inappropriate Schedule Of Drug Administration 20 1.6 1.6 no signal
101 Blood Glucose Fluctuation 3 1.6 1.6 no signal
102 Status Epilepticus 3 1.5 1.5 no signal
103 Sexual Dysfunction 3 1.5 1.5 no signal
104 Abnormal Dreams 7 1.5 1.5 no signal
105 Product Physical Issue 5 1.5 1.5 no signal
106 Schizophrenia 3 1.4 1.4 no signal
107 Wrong Technique In Product Usage Process 49 1.4 1.4 no signal
108 Extrapyramidal Disorder 5 1.2 1.2 no signal
109 Tardive Dyskinesia 5 1.0 1.0 no signal
110 Suicide Attempt 10 1.0 1.0 no signal
111 Intentional Self-injury 3 0.9 0.9 no signal
112 Device Breakage 3 0.4 0.4 no signal