OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Dextromethorphan Hydrobromide

176 flagged reaction(s) · 4,905 total co-reports · max PRR 40.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Drug Toxicity 79 40.3 41.3 signal
2 Folliculitis 43 29.3 29.7 signal
3 Serotonin Syndrome 78 28.7 29.4 signal
4 Helicobacter Infection 38 26.2 26.5 signal
5 Pemphigus 41 23.2 23.5 signal
6 Drug Abuse 272 22.8 25.0 signal
7 Autoimmune Disorder 31 22.7 23.0 signal
8 Hand Deformity 36 19.3 19.5 signal
9 Bursitis 32 18.6 18.8 signal
10 Joint Range Of Motion Decreased 35 18.4 18.6 signal
11 Respiratory Arrest 72 18.2 18.6 signal
12 Mydriasis 31 17.0 17.1 signal
13 Completed Suicide 179 14.9 15.8 signal
14 Pericarditis 35 14.7 14.9 signal
15 Fibromyalgia 47 13.6 13.8 signal
16 Liver Injury 44 12.8 12.9 signal
17 Sciatica 28 12.4 12.5 signal
18 Glossodynia 38 11.9 12.1 signal
19 Intentional Drug Misuse 36 11.9 12.0 signal
20 Irritable Bowel Syndrome 36 11.8 11.9 signal
21 Synovitis 30 11.7 11.8 signal
22 Poisoning 19 10.6 10.6 signal
23 Cardio-respiratory Arrest 61 10.2 10.3 signal
24 Pulmonary Congestion 19 10.1 10.1 signal
25 Toxicity To Various Agents 237 9.9 10.7 signal
26 Interstitial Lung Disease 68 9.9 10.1 signal
27 Intentional Overdose 86 9.5 9.7 signal
28 Disseminated Intravascular Coagulation 19 9.4 9.5 signal
29 Obesity 21 9.2 9.3 signal
30 Lower Limb Fracture 25 9.2 9.2 signal
31 Erythema Multiforme 12 9.0 9.1 signal
32 Liver Disorder 57 9.0 9.2 signal
33 Type 2 Diabetes Mellitus 41 8.5 8.6 signal
34 Paranoia 21 8.5 8.5 signal
35 Accidental Overdose 44 8.4 8.5 signal
36 Exposure During Pregnancy 73 8.2 8.4 signal
37 Euphoric Mood 12 8.2 8.2 signal
38 Contraindicated Product Administered 34 7.9 8.0 signal
39 Impaired Healing 37 7.9 8.0 signal
40 Wound 31 7.8 7.9 signal
41 Wound Infection 12 7.7 7.8 signal
42 Psoriatic Arthropathy 44 7.7 7.8 signal
43 Muscle Rigidity 13 7.6 7.6 signal
44 Road Traffic Accident 45 7.5 7.6 signal
45 Hypercholesterolaemia 10 7.3 7.3 signal
46 Oesophagitis 11 7.0 7.1 signal
47 Pulmonary Fibrosis 19 7.0 7.0 signal
48 Delirium 34 6.9 7.0 signal
49 Oedema 53 6.9 7.0 signal
50 Rebound Effect 11 6.8 6.8 signal
51 Gait Inability 31 6.6 6.6 signal
52 Caesarean Section 11 6.6 6.6 signal
53 Systemic Lupus Erythematosus 33 6.5 6.6 signal
54 Hepatic Function Abnormal 34 6.4 6.5 signal
55 Cardiac Arrest 75 6.3 6.5 signal
56 Therapy Non-responder 40 6.3 6.4 signal
57 Intentional Product Misuse 76 6.1 6.3 signal
58 Injury 61 6.0 6.2 signal
59 Drug Effect Less Than Expected 12 6.0 6.0 signal
60 Drug Eruption 15 6.0 6.0 signal
61 Altered State Of Consciousness 18 5.8 5.9 signal
62 Respiratory Depression 10 5.7 5.7 signal
63 Sleep Disorder 57 5.7 5.8 signal
64 Sinus Tachycardia 11 5.4 5.5 signal
65 Prescribed Overdose 15 5.4 5.5 signal
66 Inflammation 39 5.3 5.4 signal
67 Pneumothorax 12 5.3 5.3 signal
68 Myoclonus 9 5.3 5.3 signal
69 Sudden Death 8 5.2 5.3 signal
70 Blood Cholesterol Increased 34 5.1 5.2 signal
71 Mobility Decreased 52 5.1 5.2 signal
72 Stomatitis 44 5.1 5.1 signal
73 Pneumonia Aspiration 18 5.1 5.1 signal
74 Lung Disorder 35 5.0 5.1 signal
75 Night Sweats 23 5.0 5.0 signal
76 Infusion Related Reaction 47 5.0 5.0 signal
77 Wheezing 42 5.0 5.0 signal
78 Pneumocystis Jirovecii Pneumonia 7 4.9 4.9 signal
79 Unresponsive To Stimuli 18 4.9 4.9 signal
80 Bronchospasm 10 4.9 4.9 signal
81 Coma 33 4.8 4.9 signal
82 Pregnancy 14 4.8 4.9 signal
83 Oral Candidiasis 9 4.8 4.9 signal
84 Suicide Attempt 42 4.8 4.9 signal
85 Depressed Level Of Consciousness 27 4.8 4.8 signal
86 Drug-induced Liver Injury 21 4.8 4.8 signal
87 Dry Mouth 55 4.8 4.8 signal
88 Ataxia 8 4.7 4.7 signal
89 Shock 15 4.6 4.6 signal
90 Laryngitis 7 4.5 4.5 signal
91 Ill-defined Disorder 39 4.5 4.5 signal
92 Red Blood Cell Sedimentation Rate Increased 7 4.4 4.4 signal
93 Arthropathy 35 4.4 4.4 signal
94 Drug Level Increased 10 4.2 4.2 signal
95 Dry Throat 6 4.1 4.1 signal
96 Hepatic Enzyme Increased 40 4.1 4.2 signal
97 Sinusitis 60 4.1 4.2 signal
98 Drug Interaction 91 4.0 4.1 signal
99 Joint Dislocation 6 4.0 4.0 signal
100 Osteoarthritis 24 4.0 4.0 signal
101 Abscess 9 4.0 4.0 signal
102 Blood Lactate Dehydrogenase Increased 9 4.0 4.0 signal
103 Brain Oedema 7 3.9 3.9 signal
104 Lower Respiratory Tract Infection 25 3.9 3.9 signal
105 Withdrawal Syndrome 23 3.8 3.8 signal
106 Urinary Retention 18 3.8 3.8 signal
107 Poisoning Deliberate 5 3.8 3.8 signal
108 Anorexia 7 3.7 3.8 signal
109 Arteriosclerosis 5 3.7 3.7 signal
110 Agitation 39 3.7 3.7 signal
111 Therapeutic Product Effect Incomplete 37 3.7 3.7 signal
112 Product Taste Abnormal 7 3.6 3.7 signal
113 Blister 29 3.6 3.6 signal
114 Eosinophilia 9 3.6 3.6 signal
115 Discomfort 31 3.6 3.6 signal
116 Musculoskeletal Pain 27 3.6 3.6 signal
117 Asthma 57 3.6 3.6 signal
118 Psychotic Disorder 15 3.6 3.6 signal
119 Covid-19 Pneumonia 6 3.5 3.5 signal
120 Prescribed Underdose 10 3.5 3.5 signal
121 Premature Delivery 8 3.5 3.5 signal
122 Aggression 25 3.5 3.5 signal
123 Coordination Abnormal 7 3.5 3.5 signal
124 Emphysema 5 3.5 3.5 signal
125 Muscle Spasticity 6 3.4 3.4 signal
126 Cytomegalovirus Infection 8 3.4 3.4 signal
127 Pulmonary Arterial Hypertension 7 3.4 3.4 signal
128 Hallucination, Visual 10 3.3 3.3 signal
129 Joint Swelling 57 3.3 3.4 signal
130 Face Oedema 8 3.3 3.3 signal
131 Retching 10 3.3 3.3 signal
132 Drug Reaction With Eosinophilia And Systemic Symptoms 12 3.3 3.3 signal
133 Hip Arthroplasty 7 3.2 3.2 signal
134 Delusion 7 3.2 3.2 signal
135 Foot Deformity 5 3.2 3.2 signal
136 Neutrophil Count Decreased 18 3.1 3.1 signal
137 Sleep Disorder Due To A General Medical Condition 7 3.0 3.0 signal
138 Anaphylactic Shock 11 3.0 3.0 signal
139 Adverse Drug Reaction 37 2.9 2.9 signal
140 Overdose 89 2.9 2.9 signal
141 Decreased Immune Responsiveness 4 2.9 2.9 no signal
142 Stevens-johnson Syndrome 9 2.8 2.8 signal
143 Ischaemic Stroke 7 2.7 2.7 signal
144 Blood Creatine Phosphokinase Increased 11 2.6 2.6 signal
145 Pharyngitis Streptococcal 4 2.6 2.6 no signal
146 Acute Hepatic Failure 5 2.6 2.6 no signal
147 Disability 7 2.5 2.5 signal
148 Status Epilepticus 4 2.5 2.5 no signal
149 Metastases To Lung 4 2.4 2.4 no signal
150 Multi-organ Failure 6 2.4 2.4 no signal
151 Therapeutic Product Effect Decreased 15 2.4 2.4 signal
152 Medication Error 18 2.3 2.3 signal
153 Tooth Extraction 4 2.2 2.3 no signal
154 Personality Change 3 2.2 2.2 no signal
155 Cytokine Release Syndrome 6 2.2 2.2 no signal
156 Hallucination, Auditory 5 2.2 2.2 no signal
157 Metastases To Central Nervous System 4 2.2 2.2 no signal
158 Rheumatoid Arthritis 35 2.2 2.2 signal
159 Palmar-plantar Erythrodysaesthesia Syndrome 7 2.1 2.1 no signal
160 Intentional Self-injury 6 2.1 2.1 no signal
161 Maternal Exposure During Pregnancy 26 2.1 2.1 signal
162 Malignant Neoplasm Progression 30 2.1 2.1 signal
163 Knee Arthroplasty 6 2.0 2.0 no signal
164 Abnormal Behaviour 11 1.9 1.9 no signal
165 Sedation 7 1.9 1.9 no signal
166 Myocarditis 3 1.9 1.9 no signal
167 Neuroleptic Malignant Syndrome 3 1.8 1.8 no signal
168 Incorrect Product Administration Duration 5 1.7 1.7 no signal
169 Libido Decreased 3 1.7 1.7 no signal
170 Expired Product Administered 8 1.7 1.7 no signal
171 Drug Exposure During Pregnancy 6 1.2 1.2 no signal
172 Premature Baby 5 1.2 1.2 no signal
173 Product Complaint 4 1.1 1.1 no signal
174 Therapeutic Response Shortened 5 1.1 1.1 no signal
175 Drug Dependence 21 0.9 0.9 no signal
176 Pharmaceutical Product Complaint 3 0.8 0.8 no signal