OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Dextromethorphan

353 flagged reaction(s) · 17,882 total co-reports · max PRR 30.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Accidental Overdose 404 30.7 32.3 signal
2 Drug Abuse 722 23.9 26.3 signal
3 Serotonin Syndrome 152 22.0 22.4 signal
4 Poisoning 71 15.5 15.7 signal
5 Mydriasis 72 15.5 15.6 signal
6 Completed Suicide 352 11.5 12.0 signal
7 Toxicity To Various Agents 691 11.3 12.4 signal
8 Euphoric Mood 42 11.2 11.3 signal
9 Folliculitis 40 10.7 10.7 signal
10 Helicobacter Infection 38 10.3 10.3 signal
11 Drug Toxicity 51 10.2 10.2 signal
12 Bursitis 43 9.8 9.9 signal
13 Cardio-respiratory Arrest 145 9.5 9.7 signal
14 Respiratory Arrest 92 9.1 9.2 signal
15 Respiratory Depression 36 8.1 8.1 signal
16 Pemphigus 36 8.0 8.0 signal
17 Intentional Overdose 184 7.9 8.1 signal
18 Full Blood Count Abnormal 30 7.8 7.9 signal
19 Eosinophilia 49 7.7 7.8 signal
20 Overdose 597 7.6 8.1 signal
21 Hand Deformity 36 7.6 7.6 signal
22 Coeliac Disease 25 7.0 7.0 signal
23 Autoimmune Disorder 24 6.9 6.9 signal
24 Back Injury 27 6.9 6.9 signal
25 Joint Range Of Motion Decreased 33 6.8 6.8 signal
26 Liver Injury 59 6.7 6.8 signal
27 Pulmonary Congestion 31 6.4 6.5 signal
28 Psychomotor Hyperactivity 39 6.4 6.5 signal
29 Sleep Disorder Due To A General Medical Condition 37 6.3 6.3 signal
30 Obesity 35 6.0 6.1 signal
31 Sinus Disorder 43 6.0 6.0 signal
32 Pericarditis 36 5.9 6.0 signal
33 Hypercholesterolaemia 20 5.7 5.8 signal
34 Synovitis 36 5.5 5.5 signal
35 Fibromyalgia 48 5.4 5.5 signal
36 Myoclonus 23 5.3 5.3 signal
37 Unresponsive To Stimuli 49 5.2 5.3 signal
38 Adverse Reaction 25 5.2 5.2 signal
39 Wound Infection 20 5.1 5.1 signal
40 Ataxia 21 4.8 4.9 signal
41 Glossodynia 39 4.8 4.8 signal
42 Irritable Bowel Syndrome 37 4.8 4.8 signal
43 Incorrect Product Administration Duration 35 4.7 4.8 signal
44 Product Taste Abnormal 23 4.7 4.7 signal
45 Intentional Drug Misuse 36 4.7 4.7 signal
46 Expired Product Administered 55 4.6 4.6 signal
47 Coma 79 4.6 4.6 signal
48 Hallucination 122 4.5 4.5 signal
49 Depressed Level Of Consciousness 64 4.5 4.5 signal
50 Incorrect Drug Administration Duration 46 4.4 4.5 signal
51 Leukocytosis 29 4.4 4.4 signal
52 Gait Inability 53 4.4 4.4 signal
53 Contraindicated Product Administered 48 4.4 4.4 signal
54 Productive Cough 75 4.4 4.4 signal
55 Drug Level Increased 26 4.3 4.3 signal
56 Mental Impairment 38 4.3 4.3 signal
57 Respiratory Disorder 46 4.2 4.2 signal
58 Hallucination, Visual 32 4.2 4.2 signal
59 Wheezing 90 4.2 4.2 signal
60 Agitation 112 4.2 4.2 signal
61 Pneumonia Aspiration 37 4.1 4.1 signal
62 Aspiration 16 4.1 4.1 signal
63 Paranoia 25 4.0 4.0 signal
64 Drug Interaction 228 3.9 4.0 signal
65 Delirium 49 3.9 3.9 signal
66 Wound 39 3.9 3.9 signal
67 No Adverse Event 247 3.8 3.9 signal
68 Initial Insomnia 14 3.8 3.8 signal
69 Cardiac Arrest 112 3.7 3.8 signal
70 Neuroleptic Malignant Syndrome 16 3.7 3.7 signal
71 Atelectasis 13 3.7 3.7 signal
72 Disorientation 53 3.7 3.7 signal
73 Mental Status Changes 37 3.7 3.7 signal
74 Joint Dislocation 14 3.7 3.7 signal
75 Liver Function Test Increased 28 3.6 3.6 signal
76 Metabolic Acidosis 41 3.6 3.6 signal
77 Poisoning Deliberate 12 3.5 3.5 signal
78 Suicide Attempt 78 3.5 3.6 signal
79 Type 2 Diabetes Mellitus 43 3.5 3.5 signal
80 Sinus Tachycardia 18 3.5 3.5 signal
81 Sciatica 20 3.5 3.5 signal
82 Sleep Disorder 88 3.5 3.5 signal
83 Impaired Healing 41 3.4 3.4 signal
84 Rash Maculo-papular 27 3.3 3.4 signal
85 Electrolyte Imbalance 14 3.3 3.3 signal
86 Drug-induced Liver Injury 37 3.3 3.3 signal
87 Loss Of Personal Independence In Daily Activities 57 3.3 3.3 signal
88 Taste Disorder 24 3.3 3.3 signal
89 Brain Oedema 15 3.3 3.3 signal
90 Chronic Obstructive Pulmonary Disease 60 3.2 3.2 signal
91 Mental Disorder 50 3.2 3.2 signal
92 Cough 312 3.1 3.2 signal
93 Tachycardia 99 3.1 3.1 signal
94 Systemic Lupus Erythematosus 39 3.0 3.0 signal
95 Therapeutic Product Effect Incomplete 77 3.0 3.0 signal
96 Psychotic Disorder 32 3.0 3.0 signal
97 Coagulopathy 18 3.0 3.0 signal
98 Abnormal Behaviour 43 3.0 3.0 signal
99 Incorrect Route Of Product Administration 18 2.9 2.9 signal
100 Seasonal Allergy 15 2.9 2.9 signal
101 Drug Effective For Unapproved Indication 31 2.9 2.9 signal
102 Cardiomegaly 13 2.9 2.9 signal
103 Feeling Jittery 20 2.9 2.9 signal
104 Dysarthria 39 2.8 2.9 signal
105 Somnolence 208 2.8 2.9 signal
106 Therapy Non-responder 46 2.8 2.8 signal
107 Altered State Of Consciousness 22 2.8 2.8 signal
108 Restlessness 37 2.8 2.8 signal
109 Drug Ineffective 1,321 2.8 3.1 signal
110 Aggression 50 2.7 2.7 signal
111 Lower Limb Fracture 19 2.7 2.7 signal
112 Night Sweats 32 2.7 2.7 signal
113 Disseminated Intravascular Coagulation 14 2.7 2.7 signal
114 Nasal Congestion 58 2.7 2.7 signal
115 Blood Cholesterol Increased 46 2.7 2.7 signal
116 Hepatitis 25 2.7 2.7 signal
117 Arthropathy 54 2.7 2.7 signal
118 Intentional Product Misuse 84 2.7 2.7 signal
119 Hepatotoxicity 21 2.6 2.6 signal
120 Inappropriate Schedule Of Drug Administration 68 2.6 2.6 signal
121 Sudden Death 10 2.6 2.6 signal
122 Blister 52 2.5 2.6 signal
123 Lethargy 53 2.5 2.5 signal
124 Laryngitis 10 2.5 2.5 signal
125 Pulmonary Oedema 41 2.5 2.5 signal
126 Dizziness 452 2.5 2.6 signal
127 Confusional State 145 2.5 2.5 signal
128 Psoriatic Arthropathy 36 2.5 2.5 signal
129 Rhabdomyolysis 37 2.4 2.4 signal
130 Dry Throat 9 2.4 2.4 signal
131 Sinusitis 91 2.4 2.4 signal
132 Product Complaint 22 2.4 2.4 signal
133 Electrocardiogram Qt Prolonged 31 2.4 2.4 signal
134 Hepatic Steatosis 16 2.4 2.4 signal
135 Erythema Multiforme 8 2.4 2.4 signal
136 Hepatic Cirrhosis 16 2.4 2.4 signal
137 Dry Mouth 69 2.3 2.4 signal
138 Lower Respiratory Tract Infection 38 2.3 2.3 signal
139 Inflammation 43 2.3 2.3 signal
140 Subdural Haematoma 12 2.3 2.3 signal
141 Epilepsy 25 2.2 2.3 signal
142 Tremor 136 2.2 2.3 signal
143 Lung Disorder 40 2.2 2.2 signal
144 Rhinorrhoea 52 2.2 2.2 signal
145 Akathisia 11 2.2 2.2 signal
146 Hypoaesthesia Oral 12 2.2 2.2 signal
147 Status Epilepticus 9 2.2 2.2 signal
148 Generalised Tonic-clonic Seizure 13 2.2 2.2 signal
149 Intentional Self-injury 16 2.2 2.2 signal
150 Mania 13 2.2 2.2 signal
151 Drug Reaction With Eosinophilia And Systemic Symptoms 20 2.1 2.2 signal
152 Osteoarthritis 33 2.1 2.1 signal
153 Insomnia 207 2.1 2.2 signal
154 Encephalopathy 19 2.1 2.1 signal
155 Stomatitis 47 2.1 2.1 signal
156 Ventricular Extrasystoles 8 2.1 2.1 no signal
157 Bronchospasm 11 2.1 2.1 signal
158 Upper Respiratory Tract Infection 35 2.1 2.1 signal
159 Musculoskeletal Pain 40 2.1 2.1 signal
160 Neurotoxicity 13 2.1 2.1 signal
161 Infusion Related Reaction 49 2.0 2.0 signal
162 Sputum Discoloured 7 2.0 2.0 no signal
163 Sinus Congestion 10 2.0 2.0 signal
164 Tachypnoea 10 2.0 2.0 signal
165 Bipolar Disorder 8 2.0 2.0 no signal
166 Prescribed Overdose 14 2.0 2.0 no signal
167 Dystonia 14 2.0 2.0 no signal
168 Vitamin D Deficiency 7 2.0 2.0 no signal
169 Septic Shock 31 2.0 2.0 no signal
170 Abdominal Pain Upper 147 2.0 2.0 no signal
171 Asthma 80 2.0 2.0 no signal
172 Hypoxia 25 2.0 2.0 no signal
173 Delusion 11 2.0 2.0 no signal
174 Injury 50 1.9 1.9 no signal
175 Retching 15 1.9 1.9 no signal
176 Impaired Driving Ability 8 1.9 1.9 no signal
177 Feeling Abnormal 168 1.9 1.9 no signal
178 Brain Injury 7 1.9 1.9 no signal
179 Loss Of Consciousness 89 1.9 1.9 no signal
180 Emphysema 7 1.9 1.9 no signal
181 Ill-defined Disorder 42 1.9 1.9 no signal
182 Hyperglycaemia 25 1.9 1.9 no signal
183 C-reactive Protein Increased 25 1.9 1.9 no signal
184 Pulmonary Fibrosis 13 1.9 1.9 no signal
185 Acute Respiratory Failure 13 1.9 1.9 no signal
186 Muscle Rigidity 8 1.8 1.8 no signal
187 Road Traffic Accident 28 1.8 1.8 no signal
188 Exposure During Pregnancy 41 1.8 1.8 no signal
189 Osteopenia 10 1.8 1.8 no signal
190 Hypoaesthesia 98 1.8 1.8 no signal
191 End Stage Renal Disease 12 1.8 1.8 no signal
192 Febrile Neutropenia 43 1.8 1.8 no signal
193 Chest Discomfort 66 1.8 1.8 no signal
194 Neck Pain 36 1.8 1.8 no signal
195 Pharyngitis 8 1.8 1.8 no signal
196 Carpal Tunnel Syndrome 9 1.8 1.8 no signal
197 Tubulointerstitial Nephritis 12 1.8 1.8 no signal
198 Hypertension 135 1.7 1.8 no signal
199 Diarrhoea 409 1.7 1.8 no signal
200 Gastrointestinal Disorder 56 1.7 1.7 no signal
201 Hepatic Enzyme Increased 43 1.7 1.7 no signal
202 Red Blood Cell Sedimentation Rate Increased 7 1.7 1.7 no signal
203 Therapeutic Product Effect Decreased 28 1.7 1.7 no signal
204 Hallucination, Auditory 10 1.7 1.7 no signal
205 Hypothyroidism 20 1.7 1.7 no signal
206 Paraesthesia Oral 9 1.7 1.7 no signal
207 Anxiety 178 1.7 1.7 no signal
208 Pneumonia 201 1.7 1.7 no signal
209 Contusion 59 1.7 1.7 no signal
210 Nervousness 32 1.7 1.7 no signal
211 Haemoptysis 17 1.7 1.7 no signal
212 Heart Rate Increased 60 1.7 1.7 no signal
213 Swelling 56 1.6 1.7 no signal
214 Gastrooesophageal Reflux Disease 48 1.6 1.6 no signal
215 Hypotonia 6 1.6 1.6 no signal
216 Hip Arthroplasty 9 1.6 1.6 no signal
217 Abdominal Discomfort 99 1.6 1.6 no signal
218 Throat Tightness 16 1.6 1.6 no signal
219 Diplopia 15 1.6 1.6 no signal
220 Medication Error 32 1.6 1.6 no signal
221 Weight Fluctuation 6 1.6 1.6 no signal
222 Sedation 15 1.6 1.6 no signal
223 Hyperhidrosis 74 1.6 1.6 no signal
224 Mobility Decreased 41 1.6 1.6 no signal
225 Dyspepsia 56 1.6 1.6 no signal
226 Musculoskeletal Stiffness 50 1.6 1.6 no signal
227 Lymphopenia 8 1.6 1.6 no signal
228 Secretion Discharge 7 1.6 1.6 no signal
229 Incontinence 6 1.6 1.6 no signal
230 Nasopharyngitis 104 1.5 1.6 no signal
231 Discomfort 34 1.5 1.5 no signal
232 Condition Aggravated 169 1.5 1.5 no signal
233 Coronary Artery Disease 17 1.5 1.5 no signal
234 Pneumonitis 15 1.5 1.5 no signal
235 Feeling Hot 34 1.5 1.5 no signal
236 Urticaria 92 1.5 1.5 no signal
237 Restless Legs Syndrome 10 1.5 1.5 no signal
238 Brain Fog 8 1.5 1.5 no signal
239 Irritability 33 1.5 1.5 no signal
240 Dysstasia 16 1.5 1.5 no signal
241 Pregnancy 11 1.5 1.5 no signal
242 Inappropriate Schedule Of Product Administration 96 1.5 1.5 no signal
243 Blood Pressure Increased 83 1.5 1.5 no signal
244 Thinking Abnormal 10 1.5 1.5 no signal
245 Rebound Effect 6 1.5 1.5 no signal
246 Hypersensitivity 98 1.5 1.5 no signal
247 Unevaluable Event 39 1.4 1.4 no signal
248 Lip Swelling 17 1.4 1.4 no signal
249 Head Discomfort 9 1.4 1.4 no signal
250 Therapeutic Response Unexpected 23 1.4 1.4 no signal
251 Cold Sweat 9 1.4 1.4 no signal
252 Accident 6 1.4 1.4 no signal
253 Body Temperature Decreased 5 1.4 1.4 no signal
254 Respiratory Tract Congestion 8 1.4 1.4 no signal
255 Extra Dose Administered 20 1.4 1.4 no signal
256 Skin Reaction 7 1.4 1.4 no signal
257 Toothache 9 1.4 1.4 no signal
258 Pancreatitis Acute 11 1.4 1.4 no signal
259 Intentional Product Use Issue 43 1.3 1.3 no signal
260 Speech Disorder 25 1.3 1.3 no signal
261 Withdrawal Syndrome 20 1.3 1.3 no signal
262 Joint Swelling 57 1.3 1.3 no signal
263 Gastric Ulcer 9 1.3 1.3 no signal
264 Infusion Site Pain 6 1.3 1.3 no signal
265 Depression 107 1.3 1.3 no signal
266 Lactic Acidosis 15 1.3 1.3 no signal
267 Decreased Activity 5 1.3 1.3 no signal
268 Faeces Discoloured 10 1.3 1.3 no signal
269 Eye Swelling 17 1.3 1.3 no signal
270 Eye Disorder 15 1.3 1.3 no signal
271 Blood Count Abnormal 7 1.2 1.2 no signal
272 Disability 9 1.2 1.2 no signal
273 Vision Blurred 62 1.2 1.2 no signal
274 Foot Deformity 5 1.2 1.2 no signal
275 Eye Infection 5 1.2 1.2 no signal
276 Paraesthesia 70 1.2 1.2 no signal
277 Chromaturia 10 1.2 1.2 no signal
278 Increased Tendency To Bruise 4 1.2 1.2 no signal
279 Knee Arthroplasty 9 1.2 1.2 no signal
280 Drug Ineffective For Unapproved Indication 24 1.2 1.2 no signal
281 Feeling Cold 12 1.2 1.2 no signal
282 Back Disorder 7 1.2 1.2 no signal
283 Coordination Abnormal 6 1.2 1.2 no signal
284 Disease Recurrence 20 1.2 1.2 no signal
285 Dyskinesia 17 1.2 1.2 no signal
286 Impaired Quality Of Life 6 1.1 1.1 no signal
287 International Normalised Ratio Increased 12 1.1 1.1 no signal
288 Rheumatoid Arthritis 47 1.1 1.1 no signal
289 Anosmia 6 1.1 1.1 no signal
290 Product Use Issue 77 1.1 1.1 no signal
291 Disturbance In Attention 22 1.1 1.1 no signal
292 Pallor 11 1.1 1.1 no signal
293 Throat Irritation 18 1.1 1.1 no signal
294 Pneumocystis Jirovecii Pneumonia 4 1.1 1.1 no signal
295 Therapy Partial Responder 6 1.1 1.1 no signal
296 Hypothermia 4 1.1 1.1 no signal
297 Eye Discharge 4 1.1 1.1 no signal
298 Drug Hypersensitivity 76 1.1 1.1 no signal
299 Product Use Complaint 6 1.1 1.1 no signal
300 Scratch 4 1.1 1.1 no signal
301 Maternal Exposure During Pregnancy 34 1.1 1.1 no signal
302 Swollen Tongue 12 1.1 1.1 no signal
303 Death 329 1.0 1.1 no signal
304 Tooth Infection 5 1.0 1.0 no signal
305 Injection Site Reaction 26 1.0 1.0 no signal
306 Ocular Discomfort 4 1.0 1.0 no signal
307 Convulsion 21 1.0 1.0 no signal
308 Stevens-johnson Syndrome 8 1.0 1.0 no signal
309 Aphonia 5 1.0 1.0 no signal
310 Sneezing 8 1.0 1.0 no signal
311 Panic Attack 13 1.0 1.0 no signal
312 Prescribed Underdose 7 1.0 1.0 no signal
313 Breast Cancer 33 1.0 1.0 no signal
314 Cytopenia 4 0.9 0.9 no signal
315 Haemorrhage Intracranial 5 0.9 0.9 no signal
316 Intentional Dose Omission 9 0.9 0.9 no signal
317 Product Packaging Issue 3 0.9 0.9 no signal
318 Pharyngeal Oedema 5 0.9 0.9 no signal
319 Diarrhoea Haemorrhagic 3 0.9 0.9 no signal
320 Grand Mal Convulsion 3 0.9 0.9 no signal
321 Extrapyramidal Disorder 8 0.9 0.9 no signal
322 Cytokine Release Syndrome 6 0.9 0.9 no signal
323 Laceration 3 0.9 0.9 no signal
324 Anorexia 4 0.8 0.8 no signal
325 Sars-cov-2 Test Positive 4 0.8 0.8 no signal
326 Coronary Artery Occlusion 4 0.8 0.8 no signal
327 Drug Administration Error 9 0.8 0.8 no signal
328 Underdose 21 0.8 0.8 no signal
329 Accidental Exposure To Product 28 0.8 0.8 no signal
330 Agranulocytosis 5 0.7 0.7 no signal
331 Myocarditis 3 0.7 0.7 no signal
332 Gastric Disorder 9 0.7 0.7 no signal
333 Acute Myeloid Leukaemia 4 0.7 0.7 no signal
334 Caesarean Section 3 0.7 0.7 no signal
335 Suicidal Ideation 23 0.7 0.7 no signal
336 Blood Glucose Increased 46 0.7 0.7 no signal
337 Muscle Spasticity 3 0.7 0.7 no signal
338 Drug Dependence 39 0.7 0.7 no signal
339 Circumstance Or Information Capable Of Leading To Medication Error 8 0.7 0.7 no signal
340 Product Quality Issue 31 0.6 0.6 no signal
341 Abnormal Dreams 6 0.6 0.6 no signal
342 Device Occlusion 3 0.6 0.6 no signal
343 Incorrect Dose Administered 47 0.6 0.6 no signal
344 Plasma Cell Myeloma 8 0.6 0.6 no signal
345 Wrong Technique In Product Usage Process 41 0.6 0.6 no signal
346 Premature Delivery 3 0.5 0.5 no signal
347 Foetal Exposure During Pregnancy 15 0.5 0.5 no signal
348 Drug Withdrawal Syndrome 16 0.5 0.5 no signal
349 Drug Effect Incomplete 6 0.4 0.4 no signal
350 Skin Burning Sensation 11 0.4 0.4 no signal
351 Wrong Technique In Drug Usage Process 5 0.4 0.4 no signal
352 Device Use Error 3 0.2 0.2 no signal
353 Dependence 4 0.2 0.2 no signal