Drug

Dihydroergotamine Mesylate

43 flagged reaction(s) · 2,612 total co-reports · max PRR 197.4

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Sedation	308	197.4	260.3	signal
2	Nightmare	308	147.6	194.5	signal
3	Nephrolithiasis	222	80.5	97.4	signal
4	Hyperhidrosis	323	41.5	55.3	signal
5	Extrapyramidal Disorder	42	27.7	28.6	signal
6	Nasal Congestion	81	22.9	24.4	signal
7	Ligament Sprain	12	20.1	20.3	signal
8	Eyelid Ptosis	12	19.5	19.7	signal
9	Migraine	105	18.3	19.9	signal
10	Product Use In Unapproved Indication	262	17.7	22.1	signal
11	Tenderness	11	17.4	17.6	signal
12	Coordination Abnormal	13	15.3	15.4	signal
13	Mydriasis	11	14.2	14.3	signal
14	Ovarian Cyst	8	13.1	13.2	signal
15	Apathy	11	12.5	12.6	signal
16	Photophobia	14	12.4	12.5	signal
17	Meningioma	11	12.3	12.4	signal
18	Drug Ineffective For Unapproved Indication	41	12.2	12.5	signal
19	Treatment Failure	58	11.7	12.2	signal
20	Impaired Quality Of Life	10	11.5	11.6	signal
21	Sinus Congestion	9	11.0	11.1	signal
22	Amenorrhoea	11	10.9	11.0	signal
23	Hypocalcaemia	11	9.6	9.7	signal
24	Muscle Twitching	13	9.3	9.4	signal
25	Disability	11	9.2	9.3	signal
26	Wound Infection	6	9.1	9.2	signal
27	Upper Limb Fracture	11	9.1	9.1	signal
28	Diplopia	14	8.9	9.0	signal
29	Impaired Work Ability	11	8.5	8.5	signal
30	Drug Effect Less Than Expected	7	8.2	8.2	signal
31	Limb Discomfort	14	7.5	7.5	signal
32	Drug Ineffective	553	6.9	11.5	signal
33	Nervous System Disorder	13	6.9	6.9	signal
34	Central Nervous System Lesion	5	6.0	6.0	signal
35	Caesarean Section	4	5.6	5.6	signal
36	Expired Product Administered	11	5.5	5.5	signal
37	Crying	11	5.0	5.0	signal
38	Toxic Skin Eruption	3	4.9	4.9	signal
39	Product Availability Issue	5	3.7	3.7	signal
40	Therapeutic Response Shortened	7	3.6	3.6	signal
41	Withdrawal Syndrome	9	3.5	3.5	signal
42	Drug Exposure During Pregnancy	7	3.4	3.4	signal
43	Metrorrhagia	3	2.9	2.9	no signal