Drug
Diphenhydramine Hcl 25 Mg
Important: Reactions below are the flagged terms from this drug’s
FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate
disproportionality in spontaneous reporting, not causation.
Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
| Reaction | Co-reports (a) | PRR | ROR | Signal | |
|---|---|---|---|---|---|
| 1 | Seasonal Allergy | 13 | 25.9 | 26.3 | signal |
| 2 | Dermatitis Contact | 9 | 22.3 | 22.5 | signal |
| 3 | Infusion Site Pain | 7 | 15.4 | 15.5 | signal |
| 4 | Hospice Care | 5 | 14.3 | 14.3 | signal |
| 5 | Insurance Issue | 6 | 11.3 | 11.4 | signal |
| 6 | Increased Appetite | 6 | 9.0 | 9.0 | signal |
| 7 | Feeling Jittery | 6 | 8.8 | 8.9 | signal |
| 8 | Eye Haemorrhage | 4 | 8.4 | 8.4 | signal |
| 9 | Product Dose Omission In Error | 7 | 7.3 | 7.4 | signal |
| 10 | Anorexia | 3 | 6.4 | 6.5 | signal |
| 11 | Intentional Drug Misuse | 4 | 5.3 | 5.3 | signal |
| 12 | Expired Product Administered | 6 | 5.1 | 5.1 | signal |
| 13 | Multiple Sclerosis Relapse | 11 | 4.5 | 4.5 | signal |
| 14 | Incorrect Drug Administration Duration | 4 | 3.9 | 4.0 | signal |
| 15 | Injection Site Mass | 4 | 3.0 | 3.1 | no signal |
| 16 | Dermatitis Atopic | 5 | 2.8 | 2.8 | signal |
| 17 | Device Use Error | 3 | 2.5 | 2.5 | no signal |
| 18 | Drug Exposure During Pregnancy | 3 | 2.4 | 2.4 | no signal |
| 19 | Device Leakage | 3 | 2.0 | 2.0 | no signal |