OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Epirubicin Hydrochloride

192 flagged reaction(s) · 9,978 total co-reports · max PRR 69.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Myelosuppression 695 69.0 77.4 signal
2 Madarosis 102 29.1 29.6 signal
3 Hair Colour Changes 108 28.7 29.1 signal
4 Hair Texture Abnormal 109 27.0 27.4 signal
5 Hepatic Function Abnormal 263 23.7 24.6 signal
6 Neutrophil Count Decreased 263 21.6 22.5 signal
7 Febrile Neutropenia 367 18.4 19.5 signal
8 Bone Marrow Failure 102 16.6 16.8 signal
9 Impaired Quality Of Life 68 15.7 15.9 signal
10 Agranulocytosis 84 15.1 15.3 signal
11 White Blood Cell Count Decreased 482 14.8 15.9 signal
12 Breast Cancer Metastatic 44 13.6 13.7 signal
13 Neoplasm Progression 140 13.3 13.5 signal
14 Ejection Fraction Decreased 56 11.9 12.0 signal
15 Liver Injury 84 11.5 11.7 signal
16 Metastases To Bone 51 10.4 10.4 signal
17 Pneumocystis Jirovecii Pneumonia 30 10.0 10.0 signal
18 Drug-induced Liver Injury 91 9.8 9.9 signal
19 Metastases To Liver 51 9.7 9.7 signal
20 Palmar-plantar Erythrodysaesthesia Syndrome 66 9.4 9.5 signal
21 Cardiomyopathy 41 9.2 9.3 signal
22 Metastases To Lung 31 8.9 9.0 signal
23 Acute Myeloid Leukaemia 41 8.7 8.8 signal
24 Lymphocyte Count Decreased 42 7.9 7.9 signal
25 Alopecia 458 7.7 8.2 signal
26 Leukopenia 115 7.6 7.8 signal
27 Transaminases Increased 47 7.0 7.1 signal
28 Interstitial Lung Disease 102 7.0 7.1 signal
29 Neutropenia 274 6.7 7.0 signal
30 Polyneuropathy 23 6.4 6.4 signal
31 Mucosal Inflammation 45 5.7 5.8 signal
32 Hepatic Failure 52 5.7 5.7 signal
33 Temperature Intolerance 17 5.5 5.5 signal
34 Neutrophil Count Increased 17 5.5 5.5 signal
35 Adrenal Insufficiency 18 5.0 5.0 signal
36 Platelet Count Decreased 158 4.9 5.0 signal
37 Cytopenia 17 4.7 4.7 signal
38 Pancytopenia 79 4.7 4.7 signal
39 Myocarditis 16 4.7 4.7 signal
40 Hepatocellular Injury 20 4.7 4.7 signal
41 Blood Lactate Dehydrogenase Increased 22 4.6 4.6 signal
42 Cardiac Failure 110 4.5 4.6 signal
43 Gamma-glutamyltransferase Increased 30 4.5 4.5 signal
44 Mitral Valve Incompetence 15 4.4 4.4 signal
45 C-reactive Protein Increased 47 4.3 4.3 signal
46 Aspartate Aminotransferase Increased 65 4.1 4.1 signal
47 Haematotoxicity 11 3.9 3.9 signal
48 Hypophagia 30 3.9 3.9 signal
49 Device Use Issue 20 3.8 3.8 signal
50 Hepatic Cytolysis 14 3.8 3.8 signal
51 Gastrointestinal Disorder 97 3.6 3.7 signal
52 Alanine Aminotransferase Increased 67 3.6 3.6 signal
53 Cerebral Infarction 26 3.5 3.5 signal
54 Hypocalcaemia 20 3.5 3.5 signal
55 Supraventricular Tachycardia 10 3.5 3.5 signal
56 Neurotoxicity 18 3.4 3.4 signal
57 Hypokalaemia 47 3.4 3.4 signal
58 Septic Shock 44 3.4 3.4 signal
59 Feeding Disorder 20 3.3 3.3 signal
60 Malignant Neoplasm Progression 102 3.3 3.4 signal
61 Neuropathy Peripheral 94 3.3 3.3 signal
62 Thrombocytopenia 109 3.2 3.3 signal
63 Pneumonitis 26 3.2 3.2 signal
64 Skin Fissures 18 3.2 3.2 signal
65 Pyrexia 329 3.1 3.3 signal
66 Splenomegaly 11 3.1 3.1 signal
67 Vomiting 411 2.9 3.0 signal
68 Electrolyte Imbalance 10 2.9 2.9 signal
69 Sensory Disturbance 14 2.9 2.9 signal
70 Hepatic Encephalopathy 8 2.8 2.8 signal
71 Emotional Distress 104 2.8 2.9 signal
72 Mouth Ulceration 18 2.8 2.8 signal
73 Cold Sweat 15 2.8 2.8 signal
74 Asthenia 319 2.8 2.9 signal
75 Sinus Tachycardia 12 2.8 2.8 signal
76 Anaemia 161 2.8 2.8 signal
77 Cardiac Failure Congestive 67 2.7 2.8 signal
78 White Blood Cell Count Increased 31 2.7 2.7 signal
79 Osteonecrosis Of Jaw 20 2.7 2.7 signal
80 Hyponatraemia 45 2.7 2.7 signal
81 Drug Eruption 14 2.6 2.6 signal
82 Decreased Appetite 183 2.6 2.7 signal
83 Hypothyroidism 25 2.6 2.6 signal
84 Drug Exposure During Pregnancy 27 2.6 2.6 signal
85 Vasculitis 9 2.6 2.6 signal
86 Ventricular Extrasystoles 8 2.5 2.5 signal
87 Oral Candidiasis 10 2.5 2.5 signal
88 Paraesthesia Oral 11 2.5 2.5 signal
89 Bacteraemia 9 2.5 2.5 signal
90 Premature Baby 23 2.5 2.5 signal
91 Heart Rate Irregular 17 2.5 2.5 signal
92 Dysphagia 70 2.4 2.5 signal
93 Haemoglobin Decreased 75 2.4 2.4 signal
94 Pleural Effusion 44 2.4 2.4 signal
95 Leukocytosis 13 2.4 2.4 signal
96 Hyperglycaemia 26 2.4 2.4 signal
97 Lymphopenia 10 2.4 2.4 signal
98 Disseminated Intravascular Coagulation 10 2.3 2.3 signal
99 Metastases To Central Nervous System 9 2.3 2.3 signal
100 Haematocrit Decreased 14 2.3 2.3 signal
101 Red Blood Cell Count Decreased 20 2.3 2.3 signal
102 Electrocardiogram Qt Prolonged 25 2.3 2.3 signal
103 Injection Site Induration 9 2.3 2.3 signal
104 Discomfort 42 2.3 2.3 signal
105 Stomatitis 42 2.3 2.3 signal
106 Hyperthyroidism 10 2.3 2.3 signal
107 Myelodysplastic Syndrome 10 2.3 2.3 signal
108 Blood Alkaline Phosphatase Increased 17 2.3 2.3 signal
109 Nausea 538 2.3 2.4 signal
110 Caesarean Section 8 2.3 2.3 signal
111 Ischaemic Stroke 12 2.2 2.2 signal
112 Disease Progression 78 2.2 2.2 signal
113 Presyncope 16 2.2 2.2 signal
114 Blood Urea Increased 11 2.2 2.2 signal
115 Hepatic Steatosis 12 2.1 2.1 signal
116 Cardiogenic Shock 9 2.1 2.1 signal
117 Blood Bilirubin Increased 17 2.1 2.1 signal
118 Skin Infection 7 2.1 2.1 no signal
119 Acute Respiratory Distress Syndrome 11 2.1 2.1 signal
120 Gastroenteritis 9 2.0 2.0 no signal
121 Dehydration 82 2.0 2.0 signal
122 Pericardial Effusion 14 2.0 2.0 signal
123 Pulmonary Mass 9 2.0 2.0 no signal
124 Conjunctivitis 11 2.0 2.0 no signal
125 Chest Discomfort 61 2.0 2.0 no signal
126 Hyperbilirubinaemia 6 1.9 1.9 no signal
127 Tooth Disorder 13 1.9 1.9 no signal
128 Petechiae 6 1.9 1.9 no signal
129 Breast Cancer 54 1.9 1.9 no signal
130 Rhinorrhoea 37 1.9 1.9 no signal
131 Pulmonary Hypertension 12 1.9 1.9 no signal
132 Pulmonary Embolism 54 1.9 1.9 no signal
133 Pain In Jaw 16 1.9 1.9 no signal
134 Sudden Death 6 1.9 1.9 no signal
135 Pallor 15 1.8 1.8 no signal
136 Erythema Multiforme 5 1.8 1.8 no signal
137 Face Oedema 9 1.8 1.8 no signal
138 Squamous Cell Carcinoma 5 1.8 1.8 no signal
139 Abortion Induced 5 1.8 1.8 no signal
140 Eye Haemorrhage 7 1.7 1.7 no signal
141 Pulmonary Fibrosis 10 1.7 1.7 no signal
142 Myocardial Ischaemia 6 1.7 1.7 no signal
143 Sinus Bradycardia 5 1.7 1.7 no signal
144 Haematemesis 13 1.7 1.7 no signal
145 Osteomyelitis 9 1.6 1.6 no signal
146 Full Blood Count Decreased 10 1.6 1.6 no signal
147 Haematuria 17 1.6 1.6 no signal
148 Thyroid Cancer 6 1.6 1.6 no signal
149 Emphysema 5 1.6 1.6 no signal
150 Tooth Abscess 5 1.6 1.6 no signal
151 Hypercalcaemia 6 1.6 1.6 no signal
152 Folliculitis 5 1.6 1.6 no signal
153 Breast Cancer Female 13 1.6 1.6 no signal
154 Gastric Cancer 12 1.6 1.6 no signal
155 Depressed Level Of Consciousness 18 1.5 1.5 no signal
156 Mental Impairment 11 1.5 1.5 no signal
157 Palpitations 53 1.5 1.5 no signal
158 Paraesthesia 70 1.5 1.5 no signal
159 Appendicitis 4 1.4 1.4 no signal
160 Altered State Of Consciousness 9 1.4 1.4 no signal
161 Circulatory Collapse 7 1.4 1.4 no signal
162 Dermatitis Allergic 5 1.3 1.3 no signal
163 Injection Site Extravasation 5 1.3 1.3 no signal
164 Hypotonia 4 1.3 1.3 no signal
165 Therapy Partial Responder 6 1.3 1.3 no signal
166 Toxic Skin Eruption 4 1.3 1.3 no signal
167 Inappropriate Antidiuretic Hormone Secretion 4 1.3 1.3 no signal
168 Thyroid Disorder 6 1.3 1.3 no signal
169 Peritonitis 8 1.3 1.3 no signal
170 Hot Flush 29 1.3 1.3 no signal
171 Breast Pain 4 1.2 1.2 no signal
172 Amenorrhoea 6 1.2 1.2 no signal
173 Hypertensive Crisis 4 1.2 1.2 no signal
174 Intestinal Perforation 4 1.2 1.2 no signal
175 Pulmonary Arterial Hypertension 5 1.1 1.1 no signal
176 Maternal Exposure During Pregnancy 29 1.1 1.1 no signal
177 Diarrhoea Haemorrhagic 3 1.1 1.1 no signal
178 Grand Mal Convulsion 3 1.1 1.1 no signal
179 Posterior Reversible Encephalopathy Syndrome 3 1.0 1.0 no signal
180 Anaphylactic Shock 8 1.0 1.0 no signal
181 Anorexia 4 1.0 1.0 no signal
182 Skin Exfoliation 25 1.0 1.0 no signal
183 Neoplasm Malignant 19 0.9 0.9 no signal
184 Bipolar Disorder 3 0.9 0.9 no signal
185 Premature Delivery 4 0.8 0.8 no signal
186 Vaginal Haemorrhage 10 0.8 0.8 no signal
187 Uveitis 3 0.7 0.7 no signal
188 Osteonecrosis 7 0.7 0.7 no signal
189 Cytokine Release Syndrome 4 0.7 0.7 no signal
190 Menorrhagia 3 0.5 0.5 no signal
191 Injection Site Erythema 16 0.4 0.4 no signal
192 Hepatic Cancer 3 0.4 0.4 no signal