Drug

Estazolam

113 flagged reaction(s) · 1,895 total co-reports · max PRR 29.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Inappropriate Antidiuretic Hormone Secretion	28	29.8	30.2	signal
2	Serotonin Syndrome	50	28.3	29.0	signal
3	Altered State Of Consciousness	44	22.1	22.6	signal
4	Sopor	23	18.6	18.8	signal
5	Sudden Death	16	16.2	16.3	signal
6	Disseminated Intravascular Coagulation	21	16.1	16.3	signal
7	Delirium	47	14.7	15.0	signal
8	Neuroleptic Malignant Syndrome	14	12.7	12.8	signal
9	Suicide Attempt	69	12.3	12.7	signal
10	Sinus Tachycardia	14	10.7	10.8	signal
11	Generalised Tonic-clonic Seizure	16	10.6	10.7	signal
12	Poisoning Deliberate	9	10.5	10.5	signal
13	Electrolyte Imbalance	11	10.3	10.4	signal
14	Poisoning	12	10.3	10.3	signal
15	Pneumonia Aspiration	23	10.0	10.1	signal
16	Schizophrenia	11	9.8	9.8	signal
17	Gamma-glutamyltransferase Increased	20	9.7	9.8	signal
18	Tachypnoea	12	9.6	9.6	signal
19	Drug Interaction	138	9.4	10.0	signal
20	Electrocardiogram Qt Prolonged	31	9.3	9.4	signal
21	Coma	41	9.3	9.5	signal
22	Blood Creatine Phosphokinase Increased	25	9.2	9.3	signal
23	Lymphocyte Count Decreased	15	9.2	9.2	signal
24	Intentional Overdose	54	9.2	9.4	signal
25	Rhabdomyolysis	35	9.1	9.2	signal
26	Hepatic Function Abnormal	31	9.0	9.2	signal
27	Circulatory Collapse	14	8.8	8.9	signal
28	Hallucination, Auditory	13	8.8	8.9	signal
29	Arrhythmia	38	8.6	8.8	signal
30	Toxic Epidermal Necrolysis	12	8.6	8.6	signal
31	Blood Lactate Dehydrogenase Increased	12	8.1	8.2	signal
32	Depressed Level Of Consciousness	29	7.9	8.0	signal
33	Drug Level Increased	12	7.8	7.9	signal
34	Neutrophil Count Decreased	29	7.7	7.8	signal
35	Bradycardia	38	7.7	7.9	signal
36	Mydriasis	9	7.6	7.6	signal
37	Muscle Rigidity	8	7.2	7.3	signal
38	Leukocytosis	12	7.2	7.2	signal
39	Blood Urea Increased	11	7.1	7.1	signal
40	Ileus	8	7.0	7.1	signal
41	Blood Sodium Decreased	12	6.9	6.9	signal
42	Myocardial Ischaemia	7	6.6	6.6	signal
43	Pulmonary Mass	9	6.5	6.6	signal
44	Salivary Hypersecretion	6	6.5	6.5	signal
45	Extrapyramidal Disorder	15	6.5	6.5	signal
46	Agranulocytosis	11	6.4	6.5	signal
47	Hyponatraemia	33	6.3	6.4	signal
48	Akathisia	8	6.3	6.4	signal
49	Hypocalcaemia	11	6.3	6.3	signal
50	Cerebral Infarction	14	6.2	6.2	signal
51	Mania	9	5.9	5.9	signal
52	Bone Marrow Failure	11	5.8	5.8	signal
53	Gastric Haemorrhage	6	5.6	5.6	signal
54	Sinus Bradycardia	5	5.6	5.6	signal
55	Parkinsonism	5	5.5	5.6	signal
56	Drug Eruption	9	5.5	5.5	signal
57	Lung Infection	8	5.5	5.5	signal
58	Thirst	9	5.5	5.5	signal
59	Bladder Disorder	5	5.4	5.4	signal
60	Toxicity To Various Agents	84	5.4	5.6	signal
61	Coordination Abnormal	7	5.4	5.4	signal
62	Neutrophil Count Increased	5	5.3	5.3	signal
63	Cardiac Failure	37	5.0	5.1	signal
64	Delusion	7	4.9	4.9	signal
65	Myelosuppression	15	4.8	4.8	signal
66	Interstitial Lung Disease	21	4.7	4.7	signal
67	Erythema Multiforme	4	4.6	4.6	signal
68	Sedation	11	4.6	4.6	signal
69	Impaired Quality Of Life	6	4.5	4.5	signal
70	Affect Lability	4	4.5	4.5	signal
71	Hypokinesia	6	4.5	4.5	signal
72	Respiratory Depression	5	4.4	4.4	signal
73	Speech Disorder	21	4.3	4.4	signal
74	Pneumocystis Jirovecii Pneumonia	4	4.3	4.3	signal
75	Intentional Self-injury	8	4.3	4.3	signal
76	Hypothermia	4	4.3	4.3	signal
77	White Blood Cell Count Decreased	42	4.2	4.3	signal
78	Middle Insomnia	7	4.1	4.1	signal
79	Diabetic Ketoacidosis	9	4.1	4.1	signal
80	Completed Suicide	31	4.0	4.0	signal
81	Bipolar Disorder	4	3.9	4.0	signal
82	Stevens-johnson Syndrome	8	3.9	3.9	signal
83	Drug Abuse	30	3.9	3.9	signal
84	Drug Effect Less Than Expected	5	3.8	3.8	signal
85	Status Epilepticus	4	3.8	3.8	signal
86	Neoplasm	4	3.8	3.8	signal
87	Hyperthyroidism	5	3.7	3.7	signal
88	Dyskinesia	14	3.7	3.7	signal
89	Sexual Dysfunction	4	3.7	3.7	signal
90	Thyroid Cancer	4	3.6	3.6	signal
91	Anaphylactic Shock	8	3.4	3.4	signal
92	Anorexia	4	3.3	3.3	signal
93	Psychotic Disorder	9	3.3	3.3	signal
94	Convulsion	17	3.2	3.2	signal
95	Drug Toxicity	4	3.1	3.1	no signal
96	Withdrawal Syndrome	12	3.1	3.1	signal
97	Myelodysplastic Syndrome	4	3.0	3.0	no signal
98	Acute Myeloid Leukaemia	4	2.8	2.8	no signal
99	Dystonia	5	2.8	2.8	signal
100	Overdose	54	2.7	2.7	signal
101	Lactic Acidosis	8	2.7	2.7	signal
102	Peritonitis	5	2.6	2.6	no signal
103	Abasia	6	2.6	2.6	signal
104	Aggression	12	2.6	2.6	signal
105	Palmar-plantar Erythrodysaesthesia Syndrome	5	2.3	2.3	no signal
106	Drug Dependence	31	2.1	2.1	signal
107	Intentional Drug Misuse	4	2.0	2.0	no signal
108	Menstruation Irregular	5	2.0	2.0	no signal
109	Tardive Dyskinesia	5	1.9	1.9	no signal
110	Plasma Cell Myeloma	6	1.7	1.7	no signal
111	Circumstance Or Information Capable Of Leading To Medication Error	5	1.6	1.6	no signal
112	Gynaecomastia	4	1.4	1.4	no signal
113	Drug Withdrawal Syndrome	10	1.2	1.2	no signal