OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Estriol0.2%

118 flagged reaction(s) · 22,190 total co-reports · max PRR 455.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Subarachnoid Haemorrhage 371 455.9 579.7 signal
2 Vasculitis 367 393.1 498.4 signal
3 Anosmia 370 316.6 402.3 signal
4 Pericarditis 371 275.4 350.1 signal
5 Ventricular Tachycardia 365 272.4 344.7 signal
6 Muscle Twitching 377 200.5 256.0 signal
7 Diplopia 365 172.4 218.0 signal
8 Pain Of Skin 366 166.2 210.4 signal
9 Rash Papular 266 144.9 171.0 signal
10 Lip Swelling 391 144.0 185.6 signal
11 Eye Pruritus 362 134.3 169.4 signal
12 Transient Ischaemic Attack 367 132.4 167.7 signal
13 Blindness 366 109.7 138.8 signal
14 Angioedema 386 106.7 136.9 signal
15 Cognitive Disorder 384 100.7 129.0 signal
16 Tinnitus 372 98.6 125.2 signal
17 Disturbance In Attention 379 85.3 108.9 signal
18 Amnesia 371 69.1 87.6 signal
19 Hallucination 375 60.8 77.3 signal
20 Tachycardia 371 50.7 64.2 signal
21 Migraine 393 50.3 64.7 signal
22 Intentional Product Misuse 349 48.8 60.8 signal
23 Heart Rate Increased 375 46.0 58.4 signal
24 Muscular Weakness 394 42.1 54.1 signal
25 Palpitations 399 41.4 53.4 signal
26 Intentional Product Use Issue 285 39.3 46.8 signal
27 Visual Impairment 391 38.6 49.5 signal
28 Hyperhidrosis 379 35.6 45.3 signal
29 Dry Skin 378 34.8 44.3 signal
30 Memory Impairment 389 34.3 43.9 signal
31 Dehydration 371 33.7 42.6 signal
32 Peripheral Swelling 381 30.1 38.3 signal
33 Abdominal Discomfort 383 27.8 35.4 signal
34 Covid-19 388 26.6 33.9 signal
35 Chest Pain 390 25.5 32.6 signal
36 Myocardial Infarction 368 25.4 31.9 signal
37 Alopecia 396 24.4 31.3 signal
38 Blood Glucose Increased 367 23.5 29.5 signal
39 Abdominal Pain Upper 361 21.3 26.6 signal
40 Conjunctivitis 31 20.4 20.8 signal
41 Back Pain 390 20.3 25.9 signal
42 Feeling Abnormal 399 20.1 25.8 signal
43 Mouth Ulceration 34 19.6 19.9 signal
44 Toxic Epidermal Necrolysis 24 19.3 19.5 signal
45 Insomnia 397 18.0 23.1 signal
46 Anxiety 388 16.5 20.9 signal
47 Adverse Drug Reaction 119 16.1 17.2 signal
48 Hypothermia 13 15.5 15.6 signal
49 Pyrexia 399 14.0 17.8 signal
50 Pharyngeal Swelling 10 12.6 12.7 signal
51 Pruritus 381 12.2 15.4 signal
52 Arthralgia 413 12.1 15.5 signal
53 Tachypnoea 13 11.6 11.7 signal
54 Malaise 420 11.6 14.9 signal
55 Incorrect Product Administration Duration 19 11.3 11.4 signal
56 Vomiting 434 11.2 14.6 signal
57 Dizziness 435 10.6 13.8 signal
58 Diarrhoea Haemorrhagic 8 10.3 10.4 signal
59 Osteopenia 13 10.3 10.4 signal
60 Dyspnoea 448 9.6 12.6 signal
61 Initial Insomnia 8 9.5 9.5 signal
62 Temperature Intolerance 8 9.5 9.5 signal
63 Headache 469 9.1 12.1 signal
64 Diarrhoea 467 8.8 11.7 signal
65 Dysuria 26 8.5 8.7 signal
66 Blister 39 8.4 8.6 signal
67 Pain 427 8.4 10.8 signal
68 Aphasia 20 8.0 8.1 signal
69 Nausea 516 7.9 10.8 signal
70 Muscle Spasticity 8 7.8 7.8 signal
71 Hyponatraemia 36 7.7 7.9 signal
72 Pancreatitis Acute 14 7.6 7.6 signal
73 Fatigue 474 7.4 9.8 signal
74 Vaginal Discharge 6 7.2 7.2 signal
75 Skin Reaction 8 6.9 6.9 signal
76 Eczema 28 6.7 6.8 signal
77 Eye Infection 6 6.5 6.5 signal
78 Hunger 7 6.3 6.3 signal
79 Product Prescribing Error 12 6.1 6.2 signal
80 Ligament Sprain 5 6.1 6.1 signal
81 Product Administration Error 10 6.1 6.1 signal
82 Mass 7 6.0 6.1 signal
83 Dry Throat 5 6.0 6.0 signal
84 Eyelid Ptosis 5 5.9 6.0 signal
85 Tooth Abscess 5 5.9 5.9 signal
86 Swollen Tongue 15 5.8 5.8 signal
87 Liver Function Test Abnormal 14 5.8 5.8 signal
88 Meningioma 7 5.8 5.8 signal
89 Drug Abuse 39 5.6 5.7 signal
90 Oral Herpes 9 5.6 5.6 signal
91 Ocular Discomfort 5 5.6 5.6 signal
92 Dry Eye 22 5.5 5.6 signal
93 Oral Discomfort 6 5.2 5.2 signal
94 Cardiovascular Disorder 11 5.2 5.2 signal
95 Epilepsy 13 5.2 5.2 signal
96 Eye Inflammation 4 5.1 5.1 signal
97 Medication Error 23 5.0 5.1 signal
98 Ovarian Cyst 4 4.8 4.8 signal
99 Eye Discharge 4 4.7 4.7 signal
100 Throat Tightness 10 4.5 4.5 signal
101 Hypertensive Crisis 4 4.3 4.3 signal
102 Panic Attack 13 4.3 4.3 signal
103 Hip Fracture 11 4.1 4.2 signal
104 Polyneuropathy 4 4.1 4.1 signal
105 Pelvic Pain 6 4.0 4.0 signal
106 Fracture 6 3.8 3.8 signal
107 Acute Hepatic Failure 4 3.6 3.6 signal
108 Breast Pain 3 3.4 3.4 no signal
109 Nephropathy Toxic 3 3.3 3.3 no signal
110 Product Dose Omission In Error 7 3.2 3.2 signal
111 Injection Site Warmth 5 2.9 2.9 signal
112 Plasma Cell Myeloma 9 2.8 2.8 signal
113 Multiple Sclerosis Relapse 12 2.1 2.1 signal
114 Metrorrhagia 3 2.1 2.1 no signal
115 Vaginal Haemorrhage 7 2.0 2.0 no signal
116 Multiple Sclerosis 6 1.5 1.5 no signal
117 Breast Cancer 11 1.4 1.4 no signal
118 Injection Site Pruritus 7 1.3 1.3 no signal