OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Etonogestrel And Ethinyl Estradiol

1,146 flagged reaction(s) · 80,403 total co-reports · max PRR —
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Vaginal Mycosis 116 929.6 934.5 signal
2 Contraceptive Device Complication 16 833.4 834.0 signal
3 Vena Cava Filter Removal 15 781.3 781.8 signal
4 Vena Cava Filter Insertion 137 721.6 726.1 signal
5 Venous Stent Insertion 28 656.3 657.1 signal
6 Abnormal Withdrawal Bleeding 249 360.3 364.4 signal
7 Medical Device Site Discomfort 154 289.4 291.4 signal
8 Colposcopy 13 283.5 283.6 signal
9 May-thurner Syndrome 40 279.9 280.4 signal
10 Ectropion Of Cervix 10 275.8 275.9 signal
11 Withdrawal Bleed 151 249.2 251.0 signal
12 Thrombolysis 45 239.7 240.2 signal
13 Thrombectomy 64 231.7 232.3 signal
14 Protein S Deficiency 35 203.8 204.1 signal
15 Intentional Medical Device Removal By Patient 173 202.0 203.6 signal
16 Hypercoagulation 321 191.8 194.6 signal
17 Protein C Deficiency 20 175.2 175.4 signal
18 Pulmonary Infarction 338 157.2 159.6 signal
19 Loop Electrosurgical Excision Procedure 20 155.0 155.1 signal
20 Transverse Sinus Thrombosis 68 139.8 140.2 signal
21 Thromboembolectomy 12 137.2 137.3 signal
22 Intracranial Venous Sinus Thrombosis 136 136.4 137.2 signal
23 Antiphospholipid Antibodies Positive 72 134.7 135.2 signal
24 Protein S Decreased 18 130.8 130.9 signal
25 Post Thrombotic Syndrome 53 126.1 126.4 signal
26 Coagulation Factor Viii Level Increased 17 122.6 122.7 signal
27 Breast Prosthesis Implantation 11 121.3 121.4 signal
28 Chlamydial Infection 84 118.6 119.1 signal
29 Ovarian Cystectomy 19 112.0 112.1 signal
30 Chlamydia Test Positive 12 111.4 111.5 signal
31 Medical Device Discomfort 321 111.1 112.7 signal
32 Genital Pruritus Female 34 109.5 109.7 signal
33 Endometrial Ablation 35 104.2 104.3 signal
34 Vaginitis Bacterial 63 103.6 103.9 signal
35 Withdrawal Bleeding Irregular 24 101.8 101.9 signal
36 Female Sterilisation 49 100.1 100.3 signal
37 Menstruation Normal 30 98.7 98.8 signal
38 Unintended Pregnancy 951 95.1 99.4 signal
39 Trichomoniasis 13 93.8 93.8 signal
40 Superior Sagittal Sinus Thrombosis 68 87.3 87.6 signal
41 Cervical Dysplasia 178 84.4 85.1 signal
42 Liposuction 12 82.1 82.2 signal
43 Cervicitis 35 80.2 80.4 signal
44 Antiphospholipid Antibodies 15 79.0 79.1 signal
45 Anticoagulation Drug Level Below Therapeutic 57 75.8 76.0 signal
46 Factor V Leiden Mutation 29 74.7 74.8 signal
47 Pregnancy On Contraceptive 107 74.5 74.9 signal
48 Cystoscopy 11 71.6 71.7 signal
49 Vulvovaginal Injury 38 70.0 70.1 signal
50 Human Papilloma Virus Test Positive 28 69.8 69.9 signal
51 Adnexa Uteri Cyst 11 68.3 68.3 signal
52 Gonorrhoea 18 67.8 67.8 signal
53 Metrorrhagia 1,140 67.1 70.7 signal
54 Medical Device Site Pain 37 67.0 67.1 signal
55 Smear Cervix Abnormal 94 66.9 67.1 signal
56 Atrial Septal Defect Repair 11 65.3 65.3 signal
57 Uterine Dilation And Curettage 58 64.7 64.9 signal
58 Maternal Exposure Before Pregnancy 433 64.7 66.0 signal
59 Factor V Deficiency 10 62.5 62.5 signal
60 Vulvovaginal Discomfort 267 61.3 62.1 signal
61 Mammoplasty 48 60.9 61.0 signal
62 Pregnancy With Contraceptive Device 501 55.9 57.1 signal
63 Papilloma Viral Infection 89 54.2 54.4 signal
64 Product Shape Issue 50 53.6 53.8 signal
65 Vaginal Burning Sensation 25 52.7 52.7 signal
66 Cerebral Venous Thrombosis 95 52.2 52.5 signal
67 Phlebitis Superficial 22 51.4 51.5 signal
68 Complication Of Delivery 14 48.1 48.1 signal
69 Polycystic Ovaries 75 47.6 47.8 signal
70 Thrombophlebitis Superficial 147 47.6 48.0 signal
71 Abdominoplasty 15 45.7 45.7 signal
72 Nasal Septal Operation 16 44.9 44.9 signal
73 Bunion Operation 25 44.3 44.4 signal
74 Adenoidectomy 17 43.9 43.9 signal
75 Dysfunctional Uterine Bleeding 54 43.6 43.8 signal
76 Cervical Cyst 10 41.7 41.7 signal
77 High Risk Pregnancy 17 41.6 41.6 signal
78 Fibrocystic Breast Disease 31 41.2 41.3 signal
79 Pulmonary Embolism 3,951 41.0 49.8 signal
80 Deep Vein Thrombosis 2,663 40.4 45.8 signal
81 Vulvovaginitis 12 40.3 40.3 signal
82 Adenotonsillectomy 10 39.9 39.9 signal
83 Embolism Venous 118 38.4 38.6 signal
84 Dysthymic Disorder 13 38.3 38.4 signal
85 Tonsillectomy 64 37.8 37.9 signal
86 Mesenteric Vein Thrombosis 38 37.5 37.6 signal
87 Salpingitis 12 36.8 36.8 signal
88 Oligomenorrhoea 78 35.3 35.4 signal
89 Incorrect Drug Administration Duration 1,017 35.1 36.8 signal
90 Medical Device Change 19 35.0 35.0 signal
91 Wisdom Teeth Removal 46 34.9 35.0 signal
92 Fibroadenoma Of Breast 16 34.8 34.8 signal
93 Carotid Artery Dissection 15 34.6 34.7 signal
94 Vulvovaginal Candidiasis 46 33.9 34.0 signal
95 Cervix Disorder 25 33.9 34.0 signal
96 Vaginal Discharge 338 33.1 33.6 signal
97 Bacterial Vaginosis 52 33.0 33.1 signal
98 Encephalomalacia 19 32.9 33.0 signal
99 Venous Insufficiency 24 32.2 32.3 signal
100 Adenomyosis 19 31.6 31.6 signal
101 Sexually Transmitted Disease 14 31.5 31.5 signal
102 Arthroscopy 22 31.4 31.5 signal
103 Menorrhagia 633 31.2 32.1 signal
104 Toxic Shock Syndrome 20 31.0 31.0 signal
105 Premenstrual Syndrome 43 30.9 31.0 signal
106 Ovarian Cyst 313 30.5 31.0 signal
107 Hypomenorrhoea 81 30.4 30.5 signal
108 Patellofemoral Pain Syndrome 16 30.4 30.4 signal
109 Inappropriate Schedule Of Drug Administration 2,230 30.3 33.6 signal
110 Pelvic Inflammatory Disease 46 30.1 30.2 signal
111 Device Colour Issue 12 29.4 29.4 signal
112 Drug Exposure Before Pregnancy 30 28.8 28.9 signal
113 Pelvic Venous Thrombosis 42 28.5 28.6 signal
114 Asthma Exercise Induced 10 28.2 28.2 signal
115 Implant Site Fibrosis 12 27.6 27.7 signal
116 Ovarian Cyst Ruptured 36 27.5 27.5 signal
117 Haemangioma Of Liver 28 27.1 27.2 signal
118 Vulvovaginal Swelling 50 26.9 26.9 signal
119 Coital Bleeding 40 25.7 25.7 signal
120 Menometrorrhagia 48 25.5 25.5 signal
121 Thrombophlebitis 88 24.3 24.4 signal
122 Dyspareunia 114 24.2 24.3 signal
123 Costochondritis 40 23.9 23.9 signal
124 Antiphospholipid Syndrome 39 23.7 23.8 signal
125 Abortion Induced 229 23.7 23.9 signal
126 Vulval Disorder 16 23.5 23.5 signal
127 Peripheral Embolism 27 22.5 22.6 signal
128 Abortion 67 22.2 22.3 signal
129 Acute Sinusitis 39 22.0 22.1 signal
130 Menstruation Delayed 231 21.6 21.8 signal
131 Abortion Missed 28 21.4 21.4 signal
132 Splenic Vein Thrombosis 11 21.4 21.4 signal
133 Leiomyoma 15 21.0 21.0 signal
134 Dysmenorrhoea 282 20.9 21.2 signal
135 Vulvovaginal Pain 102 20.7 20.8 signal
136 Cyst Removal 11 20.6 20.6 signal
137 Anogenital Warts 19 20.6 20.6 signal
138 Vulvovaginal Mycotic Infection 83 20.5 20.6 signal
139 Device Expulsion 1,377 20.5 21.8 signal
140 Device Breakage 826 20.4 21.2 signal
141 Menstrual Disorder 172 20.4 20.5 signal
142 Pleuritic Pain 58 20.3 20.3 signal
143 Vaginal Disorder 20 20.2 20.2 signal
144 Uterine Leiomyoma 151 20.0 20.1 signal
145 Breast Feeding 16 19.6 19.6 signal
146 Ectopic Pregnancy 62 19.5 19.5 signal
147 Abortion Threatened 10 19.2 19.2 signal
148 Varicose Vein 101 18.9 18.9 signal
149 Cerebral Artery Thrombosis 10 18.8 18.8 signal
150 Embolism Arterial 23 18.5 18.5 signal
151 Vaginal Infection 90 18.5 18.6 signal
152 Vaginal Odour 24 18.5 18.5 signal
153 Focal Nodular Hyperplasia 10 18.4 18.4 signal
154 Rhinitis Allergic 83 18.1 18.2 signal
155 Endometriosis 89 18.1 18.1 signal
156 Appendicectomy 65 17.7 17.7 signal
157 Genital Discomfort 10 17.5 17.5 signal
158 Angioplasty 27 17.5 17.5 signal
159 Atelectasis 170 17.0 17.1 signal
160 Pulmonary Valve Incompetence 25 16.9 16.9 signal
161 Vena Cava Thrombosis 29 16.8 16.8 signal
162 Infertility Female 26 16.5 16.6 signal
163 Mitral Valve Prolapse 28 16.2 16.2 signal
164 Cerebral Thrombosis 47 16.1 16.1 signal
165 Renal Vein Thrombosis 11 16.0 16.0 signal
166 Jugular Vein Thrombosis 29 15.9 15.9 signal
167 Uterine Enlargement 13 15.8 15.8 signal
168 Calculus Ureteric 12 15.8 15.8 signal
169 Vulvovaginal Dryness 52 15.6 15.7 signal
170 Hilar Lymphadenopathy 14 15.5 15.5 signal
171 Phlebitis 82 15.4 15.5 signal
172 Dilatation Ventricular 34 15.4 15.5 signal
173 Coagulopathy 264 15.3 15.5 signal
174 Vulvovaginal Pruritus 80 15.3 15.3 signal
175 Suppressed Lactation 12 15.2 15.2 signal
176 Tricuspid Valve Incompetence 124 15.1 15.2 signal
177 Adnexa Uteri Pain 20 15.1 15.1 signal
178 Haemorrhagic Cerebral Infarction 11 15.1 15.1 signal
179 Pleurisy 91 14.7 14.8 signal
180 Generalised Anxiety Disorder 22 14.5 14.5 signal
181 International Normalised Ratio Decreased 61 14.4 14.4 signal
182 Polymenorrhoea 48 14.3 14.4 signal
183 Amenorrhoea 246 14.2 14.4 signal
184 Venous Thrombosis 57 13.9 14.0 signal
185 Iron Deficiency Anaemia 129 13.5 13.6 signal
186 Breast Cyst 25 13.5 13.5 signal
187 Hepatic Cyst 47 13.3 13.4 signal
188 Microcytic Anaemia 29 13.3 13.4 signal
189 Breast Tenderness 104 13.2 13.3 signal
190 Genital Herpes 21 13.2 13.2 signal
191 Cerebral Venous Sinus Thrombosis 11 12.9 12.9 signal
192 Portal Vein Thrombosis 43 12.9 12.9 signal
193 Lobar Pneumonia 25 12.8 12.8 signal
194 Subclavian Vein Thrombosis 15 12.6 12.6 signal
195 Cerebral Artery Occlusion 14 12.6 12.6 signal
196 Vaginal Haemorrhage 556 12.6 12.9 signal
197 Adjustment Disorder 17 12.5 12.5 signal
198 Device Failure 197 12.5 12.6 signal
199 Medical Device Complication 97 12.4 12.5 signal
200 Fibrin D Dimer Increased 46 12.4 12.5 signal
201 Uterine Polyp 23 12.3 12.3 signal
202 Hirsutism 17 12.2 12.2 signal
203 Oophorectomy 11 11.8 11.8 signal
204 Endometrial Hyperplasia 10 11.8 11.8 signal
205 Menstruation Irregular 326 11.8 12.0 signal
206 Incorrect Product Storage 163 11.8 11.8 signal
207 Thyroid Neoplasm 34 11.7 11.7 signal
208 Breast Discharge 21 11.5 11.5 signal
209 Cholecystectomy 136 11.5 11.6 signal
210 Benign Intracranial Hypertension 15 11.3 11.3 signal
211 Substance Use 18 11.2 11.2 signal
212 Pelvic Discomfort 11 11.2 11.2 signal
213 Intra-uterine Death 19 11.2 11.2 signal
214 Vulvovaginal Burning Sensation 71 11.2 11.2 signal
215 Plantar Fasciitis 39 11.1 11.2 signal
216 Migraine With Aura 31 11.0 11.0 signal
217 Attention Deficit/hyperactivity Disorder 37 10.9 10.9 signal
218 Lumbar Radiculopathy 13 10.7 10.7 signal
219 Cardiac Aneurysm 11 10.6 10.6 signal
220 Vitamin B12 Deficiency 44 10.5 10.5 signal
221 Haemorrhagic Disorder 12 10.5 10.5 signal
222 Streptococcus Test Positive 12 10.4 10.4 signal
223 Bronchial Hyperreactivity 13 10.4 10.4 signal
224 Benign Breast Neoplasm 11 10.3 10.3 signal
225 Anxiety Disorder 36 10.3 10.3 signal
226 Gastric Bypass 23 10.1 10.2 signal
227 Product Colour Issue 53 10.0 10.1 signal
228 Caesarean Section 123 10.0 10.1 signal
229 Pulmonary Granuloma 12 10.0 10.0 signal
230 Incorrect Product Administration Duration 209 9.9 10.0 signal
231 Muscle Strain 88 9.8 9.8 signal
232 Stress Urinary Incontinence 11 9.7 9.7 signal
233 Venous Thrombosis Limb 21 9.6 9.6 signal
234 Infertility 15 9.6 9.6 signal
235 Pelvic Pain 181 9.5 9.6 signal
236 Peripheral Artery Thrombosis 14 9.5 9.5 signal
237 Metabolic Surgery 11 9.4 9.4 signal
238 Ligament Sprain 97 9.4 9.5 signal
239 Multiple Injuries 62 9.3 9.4 signal
240 Incorrect Storage Of Drug 17 9.3 9.3 signal
241 Post-traumatic Stress Disorder 63 9.0 9.0 signal
242 Hormone Level Abnormal 45 9.0 9.0 signal
243 Peripheral Venous Disease 37 8.9 8.9 signal
244 Uterine Spasm 17 8.9 8.9 signal
245 No Adverse Event 1,589 8.6 9.2 signal
246 Packed Red Blood Cell Transfusion 12 8.6 8.6 signal
247 Sinus Operation 21 8.5 8.5 signal
248 Breast Pain 94 8.5 8.5 signal
249 Migraine 821 8.3 8.6 signal
250 Hyperlipidaemia 101 8.1 8.1 signal
251 Cerebellar Infarction 14 7.9 7.9 signal
252 Breast Enlargement 27 7.9 7.9 signal
253 Nasal Septum Deviation 16 7.8 7.8 signal
254 Tension Headache 35 7.8 7.8 signal
255 Poor Quality Drug Administered 53 7.7 7.7 signal
256 Goitre 33 7.7 7.7 signal
257 Genital Rash 11 7.4 7.4 signal
258 Vascular Rupture 12 7.4 7.4 signal
259 Penis Disorder 19 7.3 7.3 signal
260 Biliary Dyskinesia 13 7.3 7.3 signal
261 Thrombosis 608 7.2 7.4 signal
262 Uterine Haemorrhage 32 7.2 7.2 signal
263 Breast Mass 50 7.1 7.1 signal
264 Iron Deficiency 33 7.1 7.1 signal
265 Abortion Spontaneous 298 7.1 7.2 signal
266 Breast Swelling 20 7.1 7.1 signal
267 Cholecystitis Chronic 50 7.1 7.1 signal
268 Herpes Simplex 47 6.9 7.0 signal
269 Muscle Cramp 13 6.9 6.9 signal
270 Dyslipidaemia 36 6.8 6.8 signal
271 Appendix Disorder 10 6.8 6.8 signal
272 Pulmonary Mass 104 6.7 6.7 signal
273 Pharyngitis 87 6.7 6.7 signal
274 Mitral Valve Incompetence 79 6.7 6.7 signal
275 Panic Disorder 27 6.7 6.7 signal
276 Cystitis Interstitial 11 6.6 6.6 signal
277 Complex Regional Pain Syndrome 10 6.4 6.4 signal
278 Libido Decreased 83 6.4 6.4 signal
279 Sinus Tachycardia 94 6.3 6.4 signal
280 Venous Occlusion 12 6.3 6.3 signal
281 Major Depression 48 6.3 6.3 signal
282 Ligament Rupture 29 6.3 6.3 signal
283 Leukocytosis 118 6.2 6.3 signal
284 Fungal Infection 215 6.2 6.2 signal
285 Lung Consolidation 18 6.1 6.1 signal
286 Poor Quality Device Used 56 6.1 6.1 signal
287 Narcolepsy 12 6.1 6.1 signal
288 Haemorrhagic Anaemia 28 6.0 6.0 signal
289 Infectious Mononucleosis 14 5.9 5.9 signal
290 Uterine Perforation 53 5.9 5.9 signal
291 Lung Infiltration 55 5.9 5.9 signal
292 Mood Swings 197 5.9 5.9 signal
293 Device Physical Property Issue 46 5.9 5.9 signal
294 Pregnancy 123 5.8 5.8 signal
295 Otitis Media 20 5.8 5.8 signal
296 Hysterectomy 52 5.8 5.8 signal
297 Emotional Disorder 184 5.7 5.7 signal
298 Melanocytic Naevus 26 5.7 5.7 signal
299 Myopia 14 5.6 5.6 signal
300 Nipple Pain 12 5.6 5.6 signal
301 Ectopic Pregnancy With Contraceptive Device 10 5.6 5.6 signal
302 Snoring 22 5.6 5.6 signal
303 Abortion Incomplete 11 5.6 5.6 signal
304 Lipoma 15 5.5 5.5 signal
305 Accidental Underdose 84 5.5 5.5 signal
306 Bipolar Disorder 63 5.5 5.5 signal
307 Normochromic Normocytic Anaemia 17 5.4 5.4 signal
308 Left Ventricular Hypertrophy 24 5.3 5.4 signal
309 Cervix Carcinoma 22 5.3 5.3 signal
310 Lung Neoplasm 24 5.3 5.3 signal
311 Urinary Tract Infection Bacterial 14 5.3 5.3 signal
312 Vitamin D Deficiency 54 5.3 5.3 signal
313 Temporomandibular Joint Syndrome 15 5.3 5.3 signal
314 Antinuclear Antibody Positive 18 5.3 5.3 signal
315 Pre-eclampsia 26 5.2 5.2 signal
316 Obesity 86 5.1 5.2 signal
317 Breast Disorder 11 5.1 5.1 signal
318 Loss Of Employment 16 5.0 5.0 signal
319 Pyelonephritis 45 5.0 5.0 signal
320 Thrombocytosis 19 5.0 5.0 signal
321 Sleep Apnoea Syndrome 99 4.9 5.0 signal
322 Cardiac Murmur 45 4.9 4.9 signal
323 Synovial Cyst 24 4.9 4.9 signal
324 Embolism 43 4.9 4.9 signal
325 Abdominal Pain Lower 130 4.9 4.9 signal
326 Loss Of Libido 46 4.9 4.9 signal
327 Uterine Disorder 12 4.9 4.9 signal
328 Medical Device Pain 11 4.9 4.9 signal
329 Autoimmune Thyroiditis 19 4.8 4.8 signal
330 Pulmonary Hypertension 105 4.8 4.8 signal
331 Tonsillitis 26 4.8 4.8 signal
332 Adjustment Disorder With Depressed Mood 10 4.7 4.7 signal
333 Electrocardiogram T Wave Inversion 11 4.7 4.7 signal
334 Flank Pain 46 4.7 4.7 signal
335 Musculoskeletal Chest Pain 76 4.7 4.7 signal
336 Drug Prescribing Error 95 4.7 4.7 signal
337 Blood Disorder 39 4.6 4.7 signal
338 Complication Associated With Device 64 4.6 4.6 signal
339 Diastolic Dysfunction 15 4.6 4.6 signal
340 Menopausal Symptoms 11 4.6 4.6 signal
341 Pulmonary Thrombosis 52 4.5 4.6 signal
342 Gallbladder Disorder 84 4.5 4.5 signal
343 Maternal Drugs Affecting Foetus 36 4.4 4.4 signal
344 Hernia Repair 12 4.4 4.4 signal
345 Essential Hypertension 12 4.4 4.4 signal
346 Pre-existing Condition Improved 29 4.4 4.4 signal
347 Hepatic Steatosis 85 4.4 4.4 signal
348 Lymphadenitis 11 4.3 4.3 signal
349 Lyme Disease 15 4.3 4.3 signal
350 Cyst 56 4.3 4.3 signal
351 Intermenstrual Bleeding 23 4.3 4.3 signal
352 Product Quality Issue 600 4.2 4.3 signal
353 Hepatic Lesion 19 4.2 4.2 signal
354 Renal Cyst 35 4.2 4.2 signal
355 Supraventricular Tachycardia 42 4.2 4.2 signal
356 Carotid Artery Occlusion 16 4.2 4.2 signal
357 Hypothyroidism 139 4.2 4.2 signal
358 Scoliosis 27 4.1 4.2 signal
359 Knee Operation 42 4.1 4.1 signal
360 Acne Cystic 13 4.1 4.1 signal
361 Cerebral Infarction 105 4.1 4.1 signal
362 Blood Pressure Diastolic Abnormal 11 4.1 4.1 signal
363 Device Kink 14 4.0 4.0 signal
364 Appendicitis 39 4.0 4.0 signal
365 Irritable Bowel Syndrome 89 4.0 4.0 signal
366 Fibula Fracture 12 3.9 3.9 signal
367 Dermal Cyst 10 3.9 3.9 signal
368 Cholelithiasis 133 3.9 3.9 signal
369 Depression 926 3.9 4.0 signal
370 Alcohol Use 15 3.8 3.8 signal
371 Subarachnoid Haemorrhage 41 3.8 3.8 signal
372 Embolic Stroke 14 3.8 3.8 signal
373 Urine Analysis Abnormal 12 3.8 3.8 signal
374 Papilloedema 18 3.8 3.8 signal
375 Seasonal Allergy 56 3.8 3.8 signal
376 Cardiomegaly 49 3.8 3.8 signal
377 Drug Administration Error 122 3.7 3.8 signal
378 Excoriation 10 3.7 3.7 signal
379 Foot Operation 19 3.7 3.7 signal
380 Peripheral Vascular Disorder 20 3.7 3.7 signal
381 Biliary Colic 11 3.7 3.7 signal
382 Gestational Diabetes 18 3.6 3.7 signal
383 Sarcoidosis 18 3.6 3.6 signal
384 Pharyngitis Streptococcal 41 3.6 3.6 signal
385 Heavy Menstrual Bleeding 30 3.6 3.6 signal
386 Intracranial Pressure Increased 21 3.6 3.6 signal
387 Chronic Sinusitis 14 3.6 3.6 signal
388 Impaired Work Ability 80 3.6 3.6 signal
389 Ventricular Hypokinesia 12 3.6 3.6 signal
390 Erythema Nodosum 13 3.5 3.5 signal
391 Affective Disorder 29 3.5 3.5 signal
392 Panic Attack 134 3.5 3.5 signal
393 Mental Disorder 160 3.5 3.5 signal
394 Ecchymosis 25 3.5 3.5 signal
395 Hypercholesterolaemia 34 3.4 3.4 signal
396 Viral Upper Respiratory Tract Infection 17 3.4 3.4 signal
397 Cholecystitis Acute 20 3.4 3.4 signal
398 Prothrombin Time Prolonged 21 3.3 3.3 signal
399 Upper Respiratory Tract Infection 160 3.3 3.3 signal
400 Bronchitis 256 3.3 3.3 signal
401 Candidiasis 14 3.3 3.3 signal
402 Gastroenteritis 50 3.3 3.3 signal
403 Viith Nerve Paralysis 12 3.3 3.3 signal
404 Glucose Tolerance Impaired 20 3.2 3.2 signal
405 Arthropod Bite 25 3.2 3.2 signal
406 Limb Operation 16 3.2 3.2 signal
407 Laceration 32 3.2 3.2 signal
408 Road Traffic Accident 140 3.2 3.2 signal
409 Gastrooesophageal Reflux Disease 268 3.2 3.2 signal
410 Drug Exposure During Pregnancy 115 3.2 3.2 signal
411 Tendonitis 51 3.1 3.1 signal
412 Haemorrhoids 64 3.1 3.1 signal
413 Skin Papilloma 13 3.1 3.1 signal
414 Blood Pressure Diastolic Increased 15 3.1 3.1 signal
415 Pregnancy With Implant Contraceptive 15 3.1 3.1 signal
416 Hydronephrosis 24 3.1 3.1 signal
417 Presyncope 77 3.0 3.0 signal
418 Hypokalaemia 146 3.0 3.0 signal
419 Transient Ischaemic Attack 107 3.0 3.0 signal
420 Pleural Effusion 192 3.0 3.0 signal
421 Activated Partial Thromboplastin Time Prolonged 16 3.0 3.0 signal
422 Ischaemic Stroke 56 3.0 3.0 signal
423 Anxiety 879 2.9 3.0 signal
424 Mood Altered 83 2.9 2.9 signal
425 Ear Disorder 14 2.9 2.9 signal
426 Increased Tendency To Bruise 28 2.9 2.9 signal
427 Heart Rate Irregular 69 2.9 2.9 signal
428 Aneurysm 15 2.9 2.9 signal
429 Gallbladder Operation 12 2.9 2.9 signal
430 Intracranial Aneurysm 12 2.9 2.9 signal
431 Hiatus Hernia 38 2.8 2.8 signal
432 Meniscus Injury 18 2.8 2.8 signal
433 Cerebral Ischaemia 15 2.8 2.8 signal
434 Product Substitution Issue 166 2.7 2.8 signal
435 Thyroid Disorder 44 2.7 2.7 signal
436 Sinus Headache 17 2.7 2.7 signal
437 Abdominal Tenderness 14 2.7 2.7 signal
438 Joint Injury 60 2.7 2.7 signal
439 Intervertebral Disc Disorder 12 2.7 2.7 signal
440 Grand Mal Convulsion 26 2.6 2.6 signal
441 Urinary Tract Infection 469 2.6 2.7 signal
442 Nephrolithiasis 126 2.6 2.6 signal
443 Hypertriglyceridaemia 16 2.6 2.6 signal
444 Facial Bones Fracture 10 2.6 2.6 signal
445 Crohn's Disease 19 2.6 2.6 signal
446 Spinal Osteoarthritis 24 2.6 2.6 signal
447 Chest Pain 503 2.6 2.6 signal
448 Ventricular Extrasystoles 28 2.6 2.6 signal
449 Intervertebral Disc Protrusion 59 2.6 2.6 signal
450 Asthma 299 2.5 2.6 signal
451 Muscle Spasms 488 2.5 2.6 signal
452 Cerebrovascular Accident 450 2.5 2.6 signal
453 Shoulder Operation 11 2.5 2.5 signal
454 Cholecystitis 31 2.5 2.5 signal
455 Escherichia Urinary Tract Infection 11 2.5 2.5 signal
456 Adverse Event 238 2.5 2.5 signal
457 Intervertebral Disc Degeneration 24 2.5 2.5 signal
458 Discomfort 155 2.4 2.4 signal
459 Streptococcal Infection 14 2.4 2.4 signal
460 Injury 177 2.4 2.4 signal
461 Visual Field Defect 18 2.4 2.4 signal
462 Sinus Bradycardia 24 2.4 2.4 signal
463 Dermatitis Contact 28 2.3 2.4 signal
464 Hyperventilation 14 2.3 2.3 signal
465 Electrocardiogram Abnormal 19 2.3 2.3 signal
466 Gastritis 63 2.3 2.3 signal
467 International Normalised Ratio Increased 69 2.3 2.3 signal
468 Bundle Branch Block Right 11 2.3 2.3 signal
469 Atrial Septal Defect 20 2.3 2.3 signal
470 Carpal Tunnel Syndrome 33 2.2 2.2 signal
471 Low Density Lipoprotein Increased 18 2.2 2.2 signal
472 Partial Seizures 12 2.2 2.2 signal
473 Stress 167 2.2 2.2 signal
474 Galactorrhoea 15 2.2 2.2 signal
475 Crying 84 2.2 2.2 signal
476 Angiopathy 13 2.2 2.2 signal
477 Product Packaging Quantity Issue 25 2.2 2.2 signal
478 Exercise Tolerance Decreased 13 2.2 2.2 signal
479 Abdominal Pain 528 2.2 2.2 signal
480 Groin Pain 20 2.2 2.2 signal
481 Right Ventricular Failure 16 2.2 2.2 signal
482 Rhinitis 18 2.1 2.1 signal
483 Sinus Disorder 44 2.1 2.1 signal
484 Upper-airway Cough Syndrome 18 2.1 2.1 signal
485 Transfusion 23 2.1 2.1 signal
486 Haemoptysis 61 2.1 2.1 signal
487 Complication Of Device Removal 37 2.1 2.1 signal
488 Sinusitis 224 2.1 2.1 signal
489 Acne 165 2.1 2.1 signal
490 Ear Pain 42 2.1 2.1 signal
491 Cystitis 69 2.1 2.1 signal
492 Hemiplegia 18 2.1 2.1 signal
493 Feeling Of Despair 10 2.0 2.0 signal
494 Lymphadenopathy 76 2.0 2.0 signal
495 Limb Injury 57 2.0 2.0 signal
496 Palpitations 246 2.0 2.0 signal
497 Infusion Site Extravasation 13 2.0 2.0 no signal
498 Genital Haemorrhage 27 2.0 2.0 no signal
499 Bursitis 25 2.0 2.0 no signal
500 Convulsion 120 2.0 2.0 no signal
501 Concussion 16 2.0 2.0 no signal
502 Ankle Fracture 32 2.0 2.0 no signal
503 Dysuria 76 2.0 2.0 no signal
504 Temperature Intolerance 21 2.0 2.0 no signal
505 Night Sweats 66 2.0 2.0 no signal
506 Musculoskeletal Pain 108 1.9 2.0 no signal
507 Kidney Infection 40 1.9 1.9 no signal
508 Micturition Urgency 23 1.9 1.9 no signal
509 Blood Pressure Diastolic Decreased 15 1.9 1.9 no signal
510 Hypertension 428 1.9 1.9 no signal
511 Haemorrhage 210 1.9 1.9 no signal
512 Expired Drug Administered 10 1.9 1.9 no signal
513 Food Allergy 15 1.9 1.9 no signal
514 Scar 34 1.9 1.9 no signal
515 Hand Fracture 14 1.9 1.9 no signal
516 Syncope 197 1.9 1.9 no signal
517 Sciatica 31 1.9 1.9 no signal
518 Treatment Noncompliance 106 1.9 1.9 no signal
519 Fibromyalgia 47 1.8 1.8 no signal
520 Haemorrhage Intracranial 29 1.8 1.8 no signal
521 Back Pain 445 1.8 1.8 no signal
522 Brain Oedema 24 1.8 1.8 no signal
523 Foot Deformity 21 1.8 1.8 no signal
524 Headache 1,177 1.8 1.8 no signal
525 Weight Increased 418 1.8 1.8 no signal
526 Neck Pain 105 1.8 1.8 no signal
527 Product Storage Error 162 1.8 1.8 no signal
528 Affect Lability 18 1.8 1.8 no signal
529 Stent Placement 15 1.8 1.8 no signal
530 Product Physical Issue 37 1.8 1.8 no signal
531 Bruxism 10 1.8 1.8 no signal
532 Foot Fracture 35 1.8 1.8 no signal
533 Folliculitis 19 1.8 1.8 no signal
534 Drug Level Below Therapeutic 10 1.7 1.7 no signal
535 Viral Infection 60 1.7 1.7 no signal
536 Diverticulum 13 1.7 1.7 no signal
537 Joint Dislocation 19 1.7 1.7 no signal
538 Panic Reaction 13 1.7 1.7 no signal
539 Activities Of Daily Living Impaired 36 1.7 1.7 no signal
540 Irritability 107 1.7 1.7 no signal
541 Autoimmune Disorder 17 1.7 1.7 no signal
542 Abnormal Loss Of Weight 12 1.7 1.7 no signal
543 Platelet Count Increased 23 1.7 1.7 no signal
544 Hemiparesis 30 1.7 1.7 no signal
545 Local Swelling 31 1.7 1.7 no signal
546 Pain In Extremity 517 1.7 1.7 no signal
547 Lymphoedema 12 1.7 1.7 no signal
548 Hypoaesthesia 260 1.7 1.7 no signal
549 Exposure During Pregnancy 106 1.6 1.6 no signal
550 Cardiac Flutter 11 1.6 1.6 no signal
551 Fear 46 1.6 1.6 no signal
552 Blood Cholesterol Increased 79 1.6 1.6 no signal
553 Head Injury 53 1.6 1.6 no signal
554 Photophobia 31 1.6 1.6 no signal
555 Left Ventricular Dysfunction 11 1.6 1.6 no signal
556 Suicidal Ideation 151 1.6 1.6 no signal
557 Cellulitis 83 1.6 1.6 no signal
558 Furuncle 13 1.6 1.6 no signal
559 Abscess 26 1.6 1.6 no signal
560 Musculoskeletal Discomfort 28 1.5 1.5 no signal
561 Acute Respiratory Failure 31 1.5 1.5 no signal
562 Obsessive-compulsive Disorder 13 1.5 1.5 no signal
563 Brain Injury 16 1.5 1.5 no signal
564 Substance Abuse 13 1.5 1.5 no signal
565 Anaemia 304 1.5 1.5 no signal
566 Troponin Increased 12 1.5 1.5 no signal
567 Joint Effusion 11 1.5 1.5 no signal
568 Pollakiuria 66 1.5 1.5 no signal
569 Haematuria 53 1.5 1.5 no signal
570 Device Difficult To Use 101 1.5 1.5 no signal
571 Haemorrhagic Stroke 12 1.5 1.5 no signal
572 Abdominal Distension 158 1.4 1.4 no signal
573 Hepatomegaly 15 1.4 1.4 no signal
574 Complication Of Device Insertion 28 1.4 1.4 no signal
575 Angina Pectoris 43 1.4 1.4 no signal
576 Muscle Tightness 24 1.4 1.4 no signal
577 Back Injury 16 1.4 1.4 no signal
578 Device Dislocation 64 1.4 1.4 no signal
579 General Physical Condition Abnormal 10 1.4 1.4 no signal
580 Anger 50 1.4 1.4 no signal
581 Oedema Peripheral 180 1.4 1.4 no signal
582 Therapeutic Response Unexpected 66 1.4 1.4 no signal
583 No Therapeutic Response 18 1.4 1.4 no signal
584 Maternal Exposure During Pregnancy 128 1.4 1.4 no signal
585 Surgery 84 1.4 1.4 no signal
586 Apathy 21 1.4 1.4 no signal
587 Embedded Device 14 1.4 1.4 no signal
588 Tachycardia 126 1.3 1.4 no signal
589 Conjunctivitis 26 1.3 1.3 no signal
590 Systemic Lupus Erythematosus 50 1.3 1.3 no signal
591 Nerve Compression 13 1.3 1.3 no signal
592 Generalised Tonic-clonic Seizure 23 1.3 1.3 no signal
593 Multiple Allergies 11 1.3 1.3 no signal
594 Product Packaging Issue 13 1.3 1.3 no signal
595 Circumstance Or Information Capable Of Leading To Medication Error 47 1.3 1.3 no signal
596 Cerebral Haemorrhage 50 1.3 1.3 no signal
597 Inappropriate Schedule Of Product Administration 247 1.3 1.3 no signal
598 Bronchospasm 20 1.3 1.3 no signal
599 Haematoma 36 1.3 1.3 no signal
600 Hidradenitis 12 1.3 1.3 no signal
601 Restless Legs Syndrome 25 1.3 1.3 no signal
602 Sensory Loss 11 1.3 1.3 no signal
603 Dyspnoea Exertional 51 1.3 1.3 no signal
604 Blindness Transient 10 1.3 1.3 no signal
605 Blood Triglycerides Increased 24 1.3 1.3 no signal
606 Acute Myocardial Infarction 40 1.3 1.3 no signal
607 Impaired Gastric Emptying 17 1.3 1.3 no signal
608 Cognitive Disorder 62 1.3 1.3 no signal
609 Contusion 128 1.3 1.3 no signal
610 Sinus Congestion 18 1.3 1.3 no signal
611 Increased Appetite 25 1.3 1.3 no signal
612 Depressed Mood 70 1.3 1.3 no signal
613 General Symptom 10 1.3 1.3 no signal
614 Paraesthesia 209 1.3 1.3 no signal
615 Sensation Of Foreign Body 11 1.2 1.2 no signal
616 Nausea 1,031 1.2 1.3 no signal
617 Small Intestinal Obstruction 16 1.2 1.2 no signal
618 Economic Problem 20 1.2 1.2 no signal
619 Vasculitis 15 1.2 1.2 no signal
620 Blindness Unilateral 18 1.2 1.2 no signal
621 Epilepsy 39 1.2 1.2 no signal
622 Gastroenteritis Viral 23 1.2 1.2 no signal
623 Drug Screen Positive 10 1.2 1.2 no signal
624 Blood Albumin Decreased 10 1.2 1.2 no signal
625 Poor Quality Sleep 27 1.2 1.2 no signal
626 Pericardial Effusion 29 1.2 1.2 no signal
627 Tenderness 13 1.2 1.2 no signal
628 Ear Infection 33 1.2 1.2 no signal
629 Product Prescribing Issue 25 1.2 1.2 no signal
630 Myositis 11 1.2 1.2 no signal
631 Aphasia 37 1.2 1.2 no signal
632 Body Temperature Increased 25 1.2 1.2 no signal
633 Body Temperature Decreased 12 1.1 1.1 no signal
634 Dermatitis 25 1.1 1.1 no signal
635 Tooth Extraction 15 1.1 1.1 no signal
636 Candida Infection 20 1.1 1.1 no signal
637 Laryngitis 13 1.1 1.1 no signal
638 Brain Neoplasm 11 1.1 1.1 no signal
639 Procedural Pain 33 1.1 1.1 no signal
640 Quality Of Life Decreased 16 1.1 1.1 no signal
641 Swelling 111 1.1 1.1 no signal
642 Disturbance In Attention 64 1.1 1.1 no signal
643 Tooth Abscess 12 1.1 1.1 no signal
644 Poor Quality Product Administered 12 1.1 1.1 no signal
645 Peripheral Coldness 16 1.1 1.1 no signal
646 Thyroid Cancer 14 1.1 1.1 no signal
647 Oropharyngeal Pain 107 1.1 1.1 no signal
648 Rash Generalised 30 1.1 1.1 no signal
649 Pneumothorax 18 1.1 1.1 no signal
650 Middle Insomnia 21 1.1 1.1 no signal
651 Hypoaesthesia Oral 17 1.1 1.1 no signal
652 Insomnia 301 1.1 1.1 no signal
653 Liver Function Test Abnormal 33 1.1 1.1 no signal
654 Pneumonia 360 1.1 1.1 no signal
655 Device Defective 18 1.1 1.1 no signal
656 Blood Iron Decreased 13 1.0 1.0 no signal
657 Hyperglycaemia 40 1.0 1.0 no signal
658 Vertigo 67 1.0 1.0 no signal
659 Exostosis 10 1.0 1.0 no signal
660 Accident 13 1.0 1.0 no signal
661 Blood Thyroid Stimulating Hormone Increased 10 1.0 1.0 no signal
662 Muscle Twitching 25 1.0 1.0 no signal
663 Initial Insomnia 11 1.0 1.0 no signal
664 Respiratory Tract Infection 28 1.0 1.0 no signal
665 Bacterial Infection 20 1.0 1.0 no signal
666 Fistula 12 1.0 1.0 no signal
667 Vomiting 499 1.0 1.0 no signal
668 Constipation 230 1.0 1.0 no signal
669 Premature Delivery 17 1.0 1.0 no signal
670 Adverse Drug Reaction 95 1.0 1.0 no signal
671 Product Prescribing Error 25 1.0 1.0 no signal
672 Impaired Driving Ability 12 1.0 1.0 no signal
673 Product Use In Unapproved Indication 256 1.0 1.0 no signal
674 Hereditary Angioedema 11 1.0 1.0 no signal
675 Hunger 14 1.0 1.0 no signal
676 White Blood Cell Count Increased 40 1.0 1.0 no signal
677 Osteoarthritis 44 1.0 1.0 no signal
678 Product Use Issue 193 1.0 1.0 no signal
679 Spinal Pain 12 1.0 1.0 no signal
680 Skin Disorder 34 1.0 1.0 no signal
681 Hot Flush 77 1.0 1.0 no signal
682 Heart Rate Decreased 36 1.0 1.0 no signal
683 Heart Rate Increased 101 1.0 1.0 no signal
684 Chest Discomfort 104 1.0 1.0 no signal
685 Inflammatory Bowel Disease 10 1.0 1.0 no signal
686 Eczema 51 1.0 1.0 no signal
687 Rotator Cuff Syndrome 13 1.0 1.0 no signal
688 Dizziness 500 1.0 1.0 no signal
689 Limb Discomfort 31 1.0 1.0 no signal
690 Pain 613 0.9 0.9 no signal
691 Disseminated Intravascular Coagulation 14 0.9 0.9 no signal
692 Nocturia 12 0.9 0.9 no signal
693 Colitis Ulcerative 44 0.9 0.9 no signal
694 Hypertensive Crisis 11 0.9 0.9 no signal
695 Osteopenia 15 0.9 0.9 no signal
696 Paranoia 17 0.9 0.9 no signal
697 Product Availability Issue 22 0.9 0.9 no signal
698 Helicobacter Infection 10 0.9 0.9 no signal
699 Adverse Reaction 13 0.9 0.9 no signal
700 Abdominal Pain Upper 201 0.9 0.9 no signal
701 Sleep Disorder 68 0.9 0.9 no signal
702 Hyperthyroidism 14 0.9 0.9 no signal
703 Respiratory Disorder 29 0.9 0.9 no signal
704 Blood Potassium Decreased 29 0.9 0.9 no signal
705 Dermatitis Allergic 12 0.9 0.9 no signal
706 Diplopia 25 0.9 0.9 no signal
707 Premature Baby 29 0.9 0.9 no signal
708 Nasal Congestion 56 0.9 0.9 no signal
709 Gingival Bleeding 13 0.9 0.9 no signal
710 Cardiomyopathy 14 0.9 0.9 no signal
711 Clostridium Difficile Colitis 10 0.9 0.9 no signal
712 Post Procedural Complication 18 0.9 0.9 no signal
713 Mass 13 0.9 0.9 no signal
714 Nervous System Disorder 29 0.9 0.9 no signal
715 Nodule 12 0.9 0.9 no signal
716 Coeliac Disease 9 0.9 0.9 no signal
717 Gastrointestinal Pain 10 0.9 0.9 no signal
718 Neuralgia 22 0.9 0.9 no signal
719 Pulmonary Congestion 12 0.9 0.9 no signal
720 Staphylococcal Infection 30 0.9 0.9 no signal
721 Ventricular Tachycardia 15 0.9 0.9 no signal
722 Paralysis 13 0.9 0.9 no signal
723 Paraesthesia Oral 13 0.9 0.9 no signal
724 Haematocrit Decreased 18 0.9 0.9 no signal
725 Red Blood Cell Sedimentation Rate Increased 10 0.9 0.9 no signal
726 Diabetes Mellitus 69 0.9 0.9 no signal
727 Dermatitis Atopic 45 0.9 0.9 no signal
728 Lung Disorder 44 0.9 0.9 no signal
729 Feeling Cold 25 0.9 0.9 no signal
730 Ileus 11 0.9 0.8 no signal
731 Arrhythmia 42 0.8 0.8 no signal
732 Feeling Hot 54 0.8 0.8 no signal
733 Hypersensitivity 163 0.8 0.8 no signal
734 Ear Discomfort 9 0.8 0.8 no signal
735 Oral Herpes 17 0.8 0.8 no signal
736 Loss Of Consciousness 112 0.8 0.8 no signal
737 Wrong Technique In Drug Usage Process 32 0.8 0.8 no signal
738 Dyspepsia 85 0.8 0.8 no signal
739 Haematemesis 22 0.8 0.8 no signal
740 Petechiae 9 0.8 0.8 no signal
741 Mental Status Changes 24 0.8 0.8 no signal
742 Dehydration 115 0.8 0.8 no signal
743 Alopecia 169 0.8 0.8 no signal
744 Anaphylactic Shock 22 0.8 0.8 no signal
745 Cardiac Arrest 71 0.8 0.8 no signal
746 Transaminases Increased 19 0.8 0.8 no signal
747 Nephropathy 8 0.8 0.8 no signal
748 Pancreatitis 45 0.8 0.8 no signal
749 Incontinence 9 0.8 0.8 no signal
750 Amnesia 55 0.8 0.8 no signal
751 Cardiogenic Shock 12 0.8 0.8 no signal
752 Dyspnoea 475 0.8 0.8 no signal
753 Feeling Jittery 16 0.8 0.8 no signal
754 Off Label Use 724 0.8 0.8 no signal
755 Device Deployment Issue 10 0.8 0.8 no signal
756 Cardio-respiratory Arrest 35 0.8 0.8 no signal
757 Face Oedema 14 0.8 0.8 no signal
758 Cyanosis 13 0.8 0.8 no signal
759 Oesophagitis 9 0.8 0.8 no signal
760 Meningioma 12 0.8 0.8 no signal
761 Generalised Oedema 10 0.8 0.8 no signal
762 Fatigue 630 0.8 0.8 no signal
763 Medication Error 45 0.8 0.8 no signal
764 Ventricular Fibrillation 9 0.8 0.8 no signal
765 Nerve Injury 9 0.8 0.8 no signal
766 Injection Site Discolouration 10 0.8 0.8 no signal
767 Fluid Retention 41 0.8 0.8 no signal
768 Orthostatic Hypotension 14 0.8 0.8 no signal
769 Abnormal Weight Gain 10 0.8 0.8 no signal
770 Type 2 Diabetes Mellitus 27 0.8 0.8 no signal
771 Central Nervous System Lesion 11 0.8 0.8 no signal
772 Cold Sweat 14 0.8 0.8 no signal
773 Drug Hypersensitivity 154 0.8 0.8 no signal
774 Hypomagnesaemia 11 0.8 0.8 no signal
775 Anhedonia 21 0.8 0.8 no signal
776 Infection 113 0.7 0.7 no signal
777 Vision Blurred 107 0.7 0.7 no signal
778 Hyperhidrosis 101 0.7 0.7 no signal
779 Coordination Abnormal 11 0.7 0.7 no signal
780 Unresponsive To Stimuli 20 0.7 0.7 no signal
781 Urinary Incontinence 23 0.7 0.7 no signal
782 Hyperbilirubinaemia 8 0.7 0.7 no signal
783 Drug Dose Omission 130 0.7 0.7 no signal
784 Splenomegaly 9 0.7 0.7 no signal
785 Weight Fluctuation 8 0.7 0.7 no signal
786 Arthritis 60 0.7 0.7 no signal
787 Nasopharyngitis 140 0.7 0.7 no signal
788 Blood Pressure Increased 116 0.7 0.7 no signal
789 Pulmonary Arterial Hypertension 11 0.7 0.7 no signal
790 Device Use Issue 13 0.7 0.7 no signal
791 Decreased Activity 8 0.7 0.7 no signal
792 Dysarthria 28 0.7 0.7 no signal
793 Feeling Abnormal 179 0.7 0.7 no signal
794 Cardiovascular Disorder 19 0.7 0.7 no signal
795 C-reactive Protein Increased 27 0.7 0.7 no signal
796 Rash Pruritic 40 0.7 0.7 no signal
797 Tinnitus 34 0.7 0.7 no signal
798 Aspiration 8 0.7 0.7 no signal
799 Swelling Face 48 0.7 0.7 no signal
800 Back Disorder 12 0.7 0.7 no signal
801 Pulmonary Fibrosis 14 0.7 0.7 no signal
802 Hyponatraemia 41 0.7 0.7 no signal
803 Thirst 13 0.7 0.7 no signal
804 Dizziness Postural 7 0.7 0.7 no signal
805 Multiple Sclerosis 35 0.7 0.7 no signal
806 Urticaria 121 0.7 0.7 no signal
807 Therapy Change 7 0.7 0.7 no signal
808 Tooth Fracture 8 0.7 0.7 no signal
809 Emotional Distress 88 0.7 0.7 no signal
810 Nervousness 38 0.7 0.7 no signal
811 Inflammation 37 0.7 0.7 no signal
812 Rectal Haemorrhage 31 0.7 0.7 no signal
813 Skin Discolouration 33 0.7 0.7 no signal
814 Abasia 18 0.7 0.7 no signal
815 Intentional Product Use Issue 63 0.7 0.7 no signal
816 Tooth Disorder 16 0.7 0.7 no signal
817 Burning Sensation 50 0.7 0.7 no signal
818 Speech Disorder 37 0.7 0.7 no signal
819 Pneumonitis 19 0.7 0.7 no signal
820 Hypersomnia 20 0.7 0.7 no signal
821 Subdural Haematoma 10 0.7 0.7 no signal
822 Electrolyte Imbalance 8 0.7 0.7 no signal
823 Epistaxis 52 0.7 0.7 no signal
824 Lip Swelling 23 0.7 0.7 no signal
825 Influenza Like Illness 57 0.7 0.7 no signal
826 Haematochezia 38 0.7 0.7 no signal
827 Arthralgia 285 0.7 0.6 no signal
828 Sexual Dysfunction 8 0.7 0.7 no signal
829 Drug Level Decreased 7 0.7 0.7 no signal
830 Accidental Overdose 25 0.7 0.6 no signal
831 Blood Urine Present 13 0.6 0.6 no signal
832 Tooth Infection 9 0.6 0.6 no signal
833 Sensory Disturbance 11 0.6 0.6 no signal
834 Peripheral Swelling 103 0.6 0.6 no signal
835 Pain In Jaw 19 0.6 0.6 no signal
836 Chills 78 0.6 0.6 no signal
837 Colitis 25 0.6 0.6 no signal
838 Gastric Disorder 23 0.6 0.6 no signal
839 Retching 14 0.6 0.6 no signal
840 Coronary Artery Occlusion 9 0.6 0.6 no signal
841 Respiratory Distress 18 0.6 0.6 no signal
842 Tendon Rupture 8 0.6 0.6 no signal
843 Weight Decreased 179 0.6 0.6 no signal
844 Flatulence 36 0.6 0.6 no signal
845 Lung Infection 10 0.6 0.6 no signal
846 Expired Product Administered 21 0.6 0.6 no signal
847 Frequent Bowel Movements 17 0.6 0.6 no signal
848 Metabolic Acidosis 20 0.6 0.6 no signal
849 Tremor 105 0.6 0.6 no signal
850 Gastric Ulcer 12 0.6 0.6 no signal
851 Disorientation 25 0.6 0.6 no signal
852 Respiratory Tract Congestion 10 0.6 0.6 no signal
853 Hypoxia 22 0.6 0.6 no signal
854 Renal Failure Acute 27 0.6 0.6 no signal
855 Skin Infection 7 0.6 0.6 no signal
856 Obstructive Airways Disorder 7 0.6 0.6 no signal
857 Influenza 70 0.6 0.6 no signal
858 Eye Infection 7 0.6 0.6 no signal
859 Unevaluable Event 47 0.6 0.6 no signal
860 Diabetes Mellitus Inadequate Control 11 0.6 0.6 no signal
861 Injection Site Urticaria 15 0.6 0.6 no signal
862 Cough 173 0.6 0.6 no signal
863 Sleep Disorder Due To A General Medical Condition 10 0.6 0.6 no signal
864 Fall 204 0.6 0.6 no signal
865 Abnormal Dreams 17 0.6 0.6 no signal
866 Gastrointestinal Disorder 54 0.6 0.6 no signal
867 Inability To Afford Medication 6 0.6 0.6 no signal
868 Toothache 11 0.6 0.6 no signal
869 Disease Recurrence 29 0.6 0.6 no signal
870 Device Issue 53 0.6 0.6 no signal
871 Respiratory Failure 44 0.6 0.6 no signal
872 Pericarditis 10 0.6 0.6 no signal
873 Upper Limb Fracture 12 0.6 0.6 no signal
874 Post Procedural Haemorrhage 7 0.6 0.6 no signal
875 Visual Acuity Reduced 20 0.6 0.6 no signal
876 Product Taste Abnormal 8 0.6 0.6 no signal
877 Abdominal Discomfort 99 0.6 0.6 no signal
878 Arthropathy 33 0.6 0.6 no signal
879 Hypothermia 6 0.6 0.6 no signal
880 Oedema 32 0.6 0.6 no signal
881 Application Site Pain 13 0.6 0.6 no signal
882 Eyelid Ptosis 6 0.6 0.6 no signal
883 Product Dose Omission 39 0.6 0.6 no signal
884 Skin Lesion 16 0.6 0.6 no signal
885 Ataxia 7 0.6 0.6 no signal
886 Thinking Abnormal 11 0.6 0.6 no signal
887 Adrenal Insufficiency 7 0.6 0.6 no signal
888 Circulatory Collapse 10 0.6 0.6 no signal
889 Throat Irritation 26 0.6 0.6 no signal
890 Poor Venous Access 6 0.6 0.6 no signal
891 Scratch 6 0.6 0.6 no signal
892 Diverticulitis 16 0.6 0.6 no signal
893 Schizophrenia 7 0.5 0.5 no signal
894 Respiratory Arrest 16 0.5 0.5 no signal
895 Lethargy 33 0.5 0.5 no signal
896 Aphonia 8 0.5 0.5 no signal
897 Renal Pain 6 0.5 0.5 no signal
898 Dystonia 11 0.5 0.5 no signal
899 Drug Ineffective For Unapproved Indication 31 0.5 0.5 no signal
900 Impaired Quality Of Life 8 0.5 0.5 no signal
901 Rash 241 0.5 0.5 no signal
902 Hypotension 111 0.5 0.5 no signal
903 Diarrhoea 355 0.5 0.5 no signal
904 Brain Fog 8 0.5 0.5 no signal
905 Photosensitivity Reaction 9 0.5 0.5 no signal
906 Nightmare 19 0.5 0.5 no signal
907 Muscular Weakness 62 0.5 0.5 no signal
908 Intentional Self-injury 11 0.5 0.5 no signal
909 Dental Caries 6 0.5 0.5 no signal
910 Eye Swelling 20 0.5 0.5 no signal
911 Blood Pressure Fluctuation 13 0.5 0.5 no signal
912 Insurance Issue 8 0.5 0.5 no signal
913 Anorexia 7 0.5 0.5 no signal
914 Pulmonary Oedema 24 0.5 0.5 no signal
915 Myalgia 91 0.5 0.5 no signal
916 Deformity 5 0.5 0.5 no signal
917 Somnolence 107 0.5 0.5 no signal
918 Proteinuria 10 0.5 0.5 no signal
919 Myocarditis 6 0.5 0.5 no signal
920 Spinal Disorder 5 0.5 0.5 no signal
921 Coronary Artery Disease 16 0.5 0.5 no signal
922 Internal Haemorrhage 6 0.5 0.5 no signal
923 Malignant Melanoma 7 0.5 0.5 no signal
924 Hernia 10 0.5 0.5 no signal
925 Glaucoma 10 0.5 0.5 no signal
926 Aggression 26 0.5 0.5 no signal
927 Throat Tightness 14 0.5 0.5 no signal
928 Prescribed Overdose 10 0.5 0.5 no signal
929 Dry Eye 25 0.5 0.5 no signal
930 Asthenia 194 0.5 0.5 no signal
931 Pyrexia 178 0.5 0.5 no signal
932 Vitreous Floaters 5 0.5 0.5 no signal
933 Intentional Dose Omission 14 0.5 0.5 no signal
934 Swollen Tongue 16 0.5 0.5 no signal
935 Ascites 15 0.5 0.5 no signal
936 Psychotic Disorder 15 0.5 0.5 no signal
937 Productive Cough 24 0.5 0.5 no signal
938 Loss Of Personal Independence In Daily Activities 24 0.5 0.5 no signal
939 Drug Interaction 80 0.5 0.5 no signal
940 Ulcer 8 0.5 0.5 no signal
941 Hypotonia 5 0.5 0.5 no signal
942 Rhinorrhoea 32 0.5 0.5 no signal
943 Movement Disorder 16 0.5 0.5 no signal
944 Motor Dysfunction 5 0.5 0.5 no signal
945 Emphysema 5 0.5 0.5 no signal
946 Suicide Attempt 30 0.5 0.5 no signal
947 Dry Throat 5 0.5 0.5 no signal
948 Rash Papular 11 0.5 0.5 no signal
949 Seizure 56 0.5 0.5 no signal
950 Secretion Discharge 6 0.5 0.5 no signal
951 Euphoric Mood 5 0.5 0.5 no signal
952 Overdose 105 0.5 0.5 no signal
953 Anosmia 7 0.5 0.5 no signal
954 Blood Alkaline Phosphatase Increased 12 0.5 0.5 no signal
955 Product Odour Abnormal 5 0.5 0.5 no signal
956 Injection Site Haematoma 7 0.5 0.5 no signal
957 Skin Fissures 9 0.5 0.5 no signal
958 Drug Effect Decreased 26 0.5 0.5 no signal
959 Poisoning 6 0.5 0.5 no signal
960 Lower Limb Fracture 9 0.4 0.4 no signal
961 Hepatic Enzyme Increased 32 0.4 0.4 no signal
962 Cardiac Disorder 44 0.4 0.4 no signal
963 Mydriasis 6 0.4 0.4 no signal
964 Musculoskeletal Stiffness 41 0.4 0.4 no signal
965 Injection Site Rash 14 0.4 0.4 no signal
966 Ankylosing Spondylitis 6 0.4 0.4 no signal
967 Diabetic Ketoacidosis 11 0.4 0.4 no signal
968 Drug Intolerance 44 0.4 0.4 no signal
969 Pruritus Generalised 10 0.4 0.4 no signal
970 Anaphylactic Reaction 25 0.4 0.4 no signal
971 Lymphoma 7 0.4 0.4 no signal
972 Bradycardia 24 0.4 0.4 no signal
973 Decreased Appetite 104 0.4 0.4 no signal
974 Basal Cell Carcinoma 7 0.4 0.4 no signal
975 Drug Effective For Unapproved Indication 13 0.4 0.4 no signal
976 Jaundice 12 0.4 0.4 no signal
977 Dysstasia 13 0.4 0.4 no signal
978 Sickle Cell Anaemia With Crisis 7 0.4 0.4 no signal
979 Malaise 194 0.4 0.4 no signal
980 Joint Swelling 53 0.4 0.4 no signal
981 Injection Site Warmth 9 0.4 0.4 no signal
982 Memory Impairment 60 0.4 0.4 no signal
983 Myocardial Ischaemia 5 0.4 0.4 no signal
984 Herpes Zoster 25 0.4 0.4 no signal
985 Ovarian Cancer 4 0.4 0.4 no signal
986 Visual Impairment 53 0.4 0.4 no signal
987 Eye Disorder 14 0.4 0.4 no signal
988 Madarosis 5 0.4 0.4 no signal
989 Infusion Related Reaction 28 0.4 0.4 no signal
990 Skin Exfoliation 35 0.4 0.4 no signal
991 Injection Site Pruritus 28 0.4 0.4 no signal
992 Pruritus 159 0.4 0.4 no signal
993 Psychomotor Hyperactivity 7 0.4 0.4 no signal
994 Blindness 17 0.4 0.4 no signal
995 Wrist Fracture 5 0.4 0.4 no signal
996 Clostridium Difficile Infection 9 0.4 0.4 no signal
997 Spinal Operation 5 0.4 0.4 no signal
998 Mental Impairment 10 0.4 0.4 no signal
999 Hepatitis C 5 0.4 0.4 no signal
1000 Restlessness 15 0.4 0.4 no signal
1001 Melaena 9 0.4 0.4 no signal
1002 Renal Disorder 19 0.4 0.4 no signal
1003 Disability 8 0.4 0.4 no signal
1004 Balance Disorder 35 0.4 0.4 no signal
1005 Abnormal Behaviour 16 0.4 0.4 no signal
1006 Intestinal Obstruction 15 0.4 0.4 no signal
1007 Multi-organ Failure 7 0.4 0.4 no signal
1008 Eye Pain 22 0.4 0.4 no signal
1009 Injection Site Erythema 49 0.4 0.4 no signal
1010 Sluggishness 4 0.4 0.4 no signal
1011 Foetal Exposure During Pregnancy 32 0.4 0.4 no signal
1012 Injection Site Reaction 27 0.4 0.4 no signal
1013 Blood Pressure Decreased 26 0.4 0.4 no signal
1014 Urinary Retention 13 0.4 0.4 no signal
1015 Psoriasis 51 0.4 0.4 no signal
1016 Product Preparation Error 8 0.4 0.4 no signal
1017 Condition Aggravated 116 0.4 0.4 no signal
1018 Liver Disorder 17 0.4 0.4 no signal
1019 Skeletal Injury 4 0.4 0.4 no signal
1020 Myocardial Infarction 67 0.4 0.4 no signal
1021 Immune System Disorder 5 0.4 0.4 no signal
1022 Eye Haemorrhage 5 0.4 0.4 no signal
1023 Flushing 38 0.4 0.4 no signal
1024 Rheumatoid Arthritis 42 0.4 0.4 no signal
1025 Dysphagia 35 0.4 0.4 no signal
1026 Blood Bilirubin Increased 10 0.4 0.4 no signal
1027 Intentional Product Misuse 32 0.4 0.3 no signal
1028 Serotonin Syndrome 7 0.3 0.3 no signal
1029 Mania 6 0.3 0.3 no signal
1030 Therapeutic Response Decreased 22 0.3 0.3 no signal
1031 Leukopenia 18 0.3 0.3 no signal
1032 Haemoglobin Decreased 37 0.3 0.3 no signal
1033 Sneezing 8 0.3 0.3 no signal
1034 Wheezing 21 0.3 0.3 no signal
1035 Gait Disturbance 68 0.3 0.3 no signal
1036 Device Use Error 12 0.3 0.3 no signal
1037 Hypoglycaemia 17 0.3 0.3 no signal
1038 Thrombocytopenia 39 0.3 0.3 no signal
1039 Skin Haemorrhage 5 0.3 0.3 no signal
1040 Dyskinesia 14 0.3 0.3 no signal
1041 Alanine Aminotransferase Increased 21 0.3 0.3 no signal
1042 Pharmaceutical Product Complaint 9 0.3 0.3 no signal
1043 Rash Erythematous 16 0.3 0.3 no signal
1044 Erythema 70 0.3 0.3 no signal
1045 Aspartate Aminotransferase Increased 18 0.3 0.3 no signal
1046 Injection Site Bruising 26 0.3 0.3 no signal
1047 Delusion 5 0.3 0.3 no signal
1048 Drug Dispensing Error 5 0.3 0.3 no signal
1049 Oxygen Saturation Decreased 18 0.3 0.3 no signal
1050 Pharyngeal Oedema 5 0.3 0.3 no signal
1051 Injection Site Extravasation 4 0.3 0.3 no signal
1052 Hair Colour Changes 4 0.3 0.3 no signal
1053 Eructation 6 0.3 0.3 no signal
1054 Confusional State 51 0.3 0.3 no signal
1055 Therapeutic Response Shortened 10 0.3 0.3 no signal
1056 Hallucination, Auditory 5 0.3 0.3 no signal
1057 Musculoskeletal Disorder 6 0.3 0.3 no signal
1058 Agitation 23 0.3 0.3 no signal
1059 Intraocular Pressure Increased 4 0.3 0.3 no signal
1060 Drug Abuse 26 0.3 0.3 no signal
1061 Injection Site Induration 4 0.3 0.3 no signal
1062 Skin Irritation 14 0.3 0.3 no signal
1063 Injection Site Swelling 23 0.3 0.3 no signal
1064 Eye Pruritus 10 0.3 0.3 no signal
1065 Hair Texture Abnormal 4 0.3 0.3 no signal
1066 Uveitis 4 0.3 0.3 no signal
1067 Acute Hepatic Failure 4 0.3 0.3 no signal
1068 Covid-19 52 0.3 0.3 no signal
1069 Therapy Cessation 15 0.3 0.3 no signal
1070 Therapeutic Product Effect Decreased 13 0.3 0.3 no signal
1071 Application Site Rash 4 0.3 0.3 no signal
1072 Peritonitis 6 0.3 0.3 no signal
1073 Device Occlusion 4 0.3 0.3 no signal
1074 Blister 16 0.3 0.3 no signal
1075 Cardiac Failure Congestive 23 0.3 0.3 no signal
1076 Dysgeusia 21 0.3 0.3 no signal
1077 Glycosylated Haemoglobin Increased 7 0.3 0.3 no signal
1078 Product Dispensing Error 6 0.3 0.3 no signal
1079 Neuropathy Peripheral 26 0.3 0.3 no signal
1080 Multiple Sclerosis Relapse 19 0.3 0.3 no signal
1081 Drug Resistance 7 0.3 0.3 no signal
1082 Eye Irritation 15 0.3 0.3 no signal
1083 Sedation 7 0.3 0.3 no signal
1084 Atrial Fibrillation 26 0.3 0.3 no signal
1085 Dry Skin 35 0.3 0.3 no signal
1086 Blood Glucose Increased 50 0.3 0.2 no signal
1087 Product Dose Omission In Error 7 0.2 0.2 no signal
1088 Blood Count Abnormal 4 0.2 0.2 no signal
1089 Hypoacusis 11 0.2 0.2 no signal
1090 Injection Site Pain 77 0.2 0.2 no signal
1091 Coma 12 0.2 0.2 no signal
1092 Psoriatic Arthropathy 10 0.2 0.2 no signal
1093 Dry Mouth 20 0.2 0.2 no signal
1094 Product Dose Omission Issue 70 0.2 0.2 no signal
1095 Muscle Spasticity 3 0.2 0.2 no signal
1096 Application Site Irritation 3 0.2 0.2 no signal
1097 Drug Ineffective 315 0.2 0.2 no signal
1098 Gastrointestinal Haemorrhage 20 0.2 0.2 no signal
1099 Incorrect Dose Administered By Device 6 0.2 0.2 no signal
1100 Ocular Hyperaemia 11 0.2 0.2 no signal
1101 Tuberculosis 3 0.2 0.2 no signal
1102 Skin Cancer 5 0.2 0.2 no signal
1103 Chronic Obstructive Pulmonary Disease 12 0.2 0.2 no signal
1104 Hallucination 17 0.2 0.2 no signal
1105 Angioedema 10 0.2 0.2 no signal
1106 Pain Of Skin 6 0.2 0.2 no signal
1107 Incorrect Route Of Drug Administration 8 0.2 0.2 no signal
1108 Blood Glucose Abnormal 4 0.2 0.2 no signal
1109 Ill-defined Disorder 13 0.2 0.2 no signal
1110 Withdrawal Syndrome 9 0.2 0.2 no signal
1111 Wrong Technique In Product Usage Process 43 0.2 0.2 no signal
1112 Treatment Failure 17 0.2 0.2 no signal
1113 Product Complaint 5 0.2 0.2 no signal
1114 General Physical Health Deterioration 23 0.2 0.2 no signal
1115 Incorrect Dose Administered 45 0.2 0.2 no signal
1116 Illness 20 0.2 0.2 no signal
1117 Mobility Decreased 14 0.2 0.2 no signal
1118 Neoplasm Malignant 13 0.2 0.2 no signal
1119 Application Site Erythema 5 0.2 0.2 no signal
1120 Breast Cancer Female 5 0.2 0.2 no signal
1121 Application Site Pruritus 4 0.2 0.2 no signal
1122 Renal Failure 23 0.2 0.2 no signal
1123 Syringe Issue 3 0.2 0.2 no signal
1124 Sepsis 19 0.2 0.2 no signal
1125 Synovitis 3 0.2 0.2 no signal
1126 Cardiac Failure 13 0.2 0.2 no signal
1127 Therapeutic Product Effect Incomplete 11 0.1 0.1 no signal
1128 Skin Burning Sensation 11 0.1 0.1 no signal
1129 Wrong Technique In Device Usage Process 7 0.1 0.1 no signal
1130 Injection Site Haemorrhage 12 0.1 0.1 no signal
1131 Device Leakage 6 0.1 0.1 no signal
1132 Intentional Overdose 9 0.1 0.1 no signal
1133 Breast Cancer 13 0.1 0.1 no signal
1134 Drug Withdrawal Syndrome 12 0.1 0.1 no signal
1135 Drug Dependence 22 0.1 0.1 no signal
1136 Device Malfunction 9 0.1 0.1 no signal
1137 Platelet Count Decreased 13 0.1 0.1 no signal
1138 Accidental Exposure To Product 12 0.1 0.1 no signal
1139 Extrapyramidal Disorder 3 0.1 0.1 no signal
1140 White Blood Cell Count Decreased 12 0.1 0.1 no signal
1141 Acute Kidney Injury 15 0.1 0.1 no signal
1142 Neutropenia 13 0.1 0.1 no signal
1143 Hospitalisation 13 0.1 0.1 no signal
1144 Product Adhesion Issue 3 0.1 0.1 no signal
1145 Death 32 0.0 0.0 no signal
1146 Vaginal Contraceptive Device Expelled 140 — — signal