OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Foscarbidopa/foslevodopa

287 flagged reaction(s) · 17,496 total co-reports · max PRR 63.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Infusion Site Pain 281 63.9 66.4 signal
2 Hypokinesia 247 49.1 50.8 signal
3 Dyskinesia 585 41.6 45.1 signal
4 Muscle Rigidity 145 34.9 35.6 signal
5 Hallucination 741 28.4 31.4 signal
6 Hallucination, Visual 180 24.6 25.2 signal
7 Delusion 108 20.0 20.2 signal
8 Movement Disorder 186 16.5 16.9 signal
9 Motor Dysfunction 56 15.8 15.9 signal
10 Skin Infection 61 15.6 15.7 signal
11 Mobility Decreased 368 14.7 15.4 signal
12 Gait Inability 148 12.8 13.0 signal
13 Psychotic Disorder 129 12.5 12.7 signal
14 Device Issue 375 12.3 12.9 signal
15 Device Occlusion 57 11.7 11.8 signal
16 Therapeutic Product Effect Incomplete 287 11.6 12.0 signal
17 Dystonia 75 11.0 11.1 signal
18 Nodule 50 10.9 11.0 signal
19 Paranoia 66 10.9 11.0 signal
20 Unresponsive To Stimuli 98 10.9 11.0 signal
21 Poor Quality Sleep 77 10.3 10.4 signal
22 General Physical Health Deterioration 371 9.2 9.6 signal
23 Cognitive Disorder 150 9.2 9.4 signal
24 Hip Fracture 101 9.0 9.1 signal
25 Musculoskeletal Disorder 60 8.9 9.0 signal
26 Orthostatic Hypotension 54 8.8 8.9 signal
27 Knee Operation 30 8.8 8.8 signal
28 Aspiration 33 8.7 8.7 signal
29 Aggression 151 8.6 8.7 signal
30 Delirium 104 8.6 8.7 signal
31 Pneumonia Aspiration 73 8.3 8.4 signal
32 Loss Of Personal Independence In Daily Activities 135 8.1 8.2 signal
33 Restlessness 104 8.1 8.2 signal
34 Speech Disorder 146 7.9 8.1 signal
35 Hallucination, Auditory 44 7.9 7.9 signal
36 Abscess 44 7.9 7.9 signal
37 Unintentional Medical Device Removal 32 7.8 7.8 signal
38 Fall 906 7.8 8.7 signal
39 Hypophagia 69 7.7 7.8 signal
40 Musculoskeletal Stiffness 225 7.3 7.5 signal
41 Feeding Disorder 50 7.1 7.2 signal
42 Device Use Issue 43 7.1 7.1 signal
43 Bedridden 32 6.9 7.0 signal
44 Tremor 403 6.9 7.2 signal
45 Disorientation 95 6.8 6.9 signal
46 Parkinsonism 23 6.7 6.7 signal
47 Salivary Hypersecretion 23 6.6 6.6 signal
48 Urosepsis 21 6.5 6.5 signal
49 Dementia 63 6.4 6.5 signal
50 Mental Disorder 97 6.3 6.4 signal
51 Injection Site Nodule 24 6.2 6.2 signal
52 Apathy 29 5.7 5.7 signal
53 Cellulitis 99 5.6 5.6 signal
54 Confusional State 314 5.5 5.7 signal
55 Dermatitis Contact 22 5.5 5.5 signal
56 Hospice Care 19 5.5 5.5 signal
57 Dysstasia 56 5.4 5.5 signal
58 Injection Site Induration 24 5.3 5.3 signal
59 Head Injury 58 5.2 5.3 signal
60 Malnutrition 20 5.1 5.1 signal
61 Skin Laceration 19 5.0 5.0 signal
62 Femur Fracture 54 4.9 5.0 signal
63 Urinary Tract Infection 294 4.9 5.1 signal
64 Epilepsy 52 4.8 4.9 signal
65 Device Use Error 58 4.8 4.9 signal
66 Abnormal Dreams 47 4.8 4.8 signal
67 Dysarthria 63 4.8 4.8 signal
68 Balance Disorder 143 4.7 4.8 signal
69 Aphasia 49 4.6 4.6 signal
70 Dysphagia 152 4.6 4.6 signal
71 Head Discomfort 28 4.5 4.5 signal
72 Limb Discomfort 49 4.5 4.5 signal
73 Rib Fracture 32 4.4 4.5 signal
74 Foot Deformity 17 4.4 4.4 signal
75 Agitation 112 4.3 4.4 signal
76 Psychomotor Hyperactivity 25 4.3 4.3 signal
77 Spinal Operation 18 4.2 4.2 signal
78 Gait Disturbance 276 4.1 4.2 signal
79 Polyneuropathy 17 4.1 4.1 signal
80 Nocturia 17 4.0 4.0 signal
81 Brain Fog 20 3.9 3.9 signal
82 Skin Reaction 19 3.8 3.8 signal
83 Mania 22 3.8 3.8 signal
84 Intestinal Obstruction 50 3.8 3.8 signal
85 Blood Pressure Fluctuation 32 3.8 3.8 signal
86 Loss Of Consciousness 169 3.7 3.8 signal
87 Skin Disorder 43 3.7 3.7 signal
88 Cystitis 40 3.6 3.6 signal
89 Device Dislocation 54 3.5 3.6 signal
90 Middle Insomnia 23 3.5 3.5 signal
91 Sudden Death 13 3.5 3.5 signal
92 Upper Limb Fracture 24 3.4 3.4 signal
93 Hypotonia 12 3.4 3.4 signal
94 Therapeutic Product Effect Decreased 52 3.3 3.3 signal
95 Drug Effect Less Than Expected 16 3.2 3.2 signal
96 Incontinence 12 3.2 3.2 signal
97 Fear 30 3.1 3.2 signal
98 Device Breakage 43 3.1 3.1 signal
99 Sluggishness 11 3.1 3.1 signal
100 Hypersomnia 31 3.1 3.1 signal
101 Respiratory Tract Infection 28 3.1 3.1 signal
102 Panic Attack 39 3.0 3.1 signal
103 Cerebral Haemorrhage 38 3.0 3.0 signal
104 Nightmare 36 2.9 3.0 signal
105 Urinary Retention 34 2.9 2.9 signal
106 Blood Pressure Abnormal 20 2.9 2.9 signal
107 Wrist Fracture 12 2.8 2.8 signal
108 Inflammation 51 2.8 2.8 signal
109 Nervousness 52 2.8 2.8 signal
110 Somnolence 199 2.8 2.9 signal
111 Hypothermia 10 2.8 2.8 signal
112 Depressed Mood 51 2.8 2.8 signal
113 Personality Change 9 2.7 2.7 signal
114 Spinal Fracture 19 2.7 2.7 signal
115 Depressed Level Of Consciousness 37 2.7 2.7 signal
116 Restless Legs Syndrome 17 2.7 2.7 signal
117 Hip Arthroplasty 14 2.6 2.6 signal
118 Product Storage Error 79 2.6 2.6 signal
119 Knee Arthroplasty 19 2.6 2.6 signal
120 Suicidal Ideation 83 2.6 2.6 signal
121 Pneumonia 288 2.5 2.6 signal
122 Diplopia 23 2.5 2.5 signal
123 Haematoma 23 2.5 2.5 signal
124 Hospitalisation 134 2.5 2.5 signal
125 Infection 124 2.4 2.5 signal
126 Discomfort 52 2.4 2.4 signal
127 Carpal Tunnel Syndrome 12 2.4 2.4 signal
128 Therapeutic Response Shortened 27 2.4 2.4 signal
129 Stress 61 2.4 2.4 signal
130 Urinary Incontinence 25 2.4 2.4 signal
131 Decreased Activity 9 2.4 2.4 signal
132 Syncope 83 2.4 2.4 signal
133 Transient Ischaemic Attack 28 2.3 2.4 signal
134 Choking 16 2.3 2.3 signal
135 Asthenia 309 2.3 2.4 signal
136 Scar 14 2.3 2.3 signal
137 Hypertensive Crisis 9 2.3 2.3 signal
138 Sensory Disturbance 13 2.3 2.3 signal
139 Emotional Disorder 25 2.3 2.3 signal
140 Device Defective 13 2.3 2.3 signal
141 Device Difficult To Use 53 2.3 2.3 signal
142 Altered State Of Consciousness 17 2.2 2.2 signal
143 Sepsis 87 2.2 2.2 signal
144 Surgery 45 2.2 2.2 signal
145 Limb Injury 21 2.2 2.2 signal
146 Dermatitis 16 2.2 2.2 signal
147 Subdural Haematoma 11 2.2 2.2 signal
148 Malaise 335 2.2 2.2 signal
149 Joint Dislocation 8 2.2 2.2 no signal
150 Thinking Abnormal 14 2.1 2.1 signal
151 Anxiety 212 2.1 2.1 signal
152 Mental Impairment 18 2.1 2.1 signal
153 Ileus 9 2.1 2.1 signal
154 Wound 20 2.0 2.0 signal
155 Aphonia 10 2.0 2.0 signal
156 Unevaluable Event 54 2.0 2.0 signal
157 Injection Site Irritation 9 2.0 2.0 no signal
158 Hypotension 140 2.0 2.0 no signal
159 Dehydration 93 2.0 2.0 no signal
160 Cardio-respiratory Arrest 29 2.0 2.0 no signal
161 Fracture 13 2.0 2.0 no signal
162 Subarachnoid Haemorrhage 7 1.9 1.9 no signal
163 Death 587 1.9 2.0 no signal
164 Weight Decreased 189 1.9 2.0 no signal
165 Malignant Melanoma 9 1.9 1.9 no signal
166 Staphylococcal Infection 22 1.9 1.9 no signal
167 Cardiac Arrest 55 1.9 1.9 no signal
168 Localised Infection 16 1.9 1.9 no signal
169 Seizure 75 1.9 1.9 no signal
170 Dysphonia 38 1.8 1.9 no signal
171 Appendicitis 6 1.8 1.8 no signal
172 Lethargy 37 1.8 1.8 no signal
173 Incorrect Product Administration Duration 13 1.8 1.8 no signal
174 Leukaemia 6 1.8 1.8 no signal
175 Disturbance In Attention 34 1.8 1.8 no signal
176 Abnormal Behaviour 25 1.8 1.8 no signal
177 Impaired Quality Of Life 9 1.8 1.8 no signal
178 Dizziness Postural 6 1.8 1.8 no signal
179 Hernia 12 1.8 1.8 no signal
180 Feeling Abnormal 145 1.7 1.7 no signal
181 Nephrolithiasis 27 1.7 1.7 no signal
182 Cataract 35 1.7 1.7 no signal
183 Initial Insomnia 6 1.7 1.7 no signal
184 Macular Degeneration 7 1.7 1.7 no signal
185 Cardiovascular Disorder 15 1.7 1.7 no signal
186 Blood Sodium Decreased 11 1.7 1.7 no signal
187 Circulatory Collapse 10 1.7 1.7 no signal
188 Muscle Spasms 107 1.7 1.7 no signal
189 Chromaturia 13 1.6 1.6 no signal
190 Muscular Weakness 65 1.6 1.6 no signal
191 Paralysis 8 1.6 1.6 no signal
192 Contusion 53 1.6 1.6 no signal
193 Pulmonary Thrombosis 6 1.6 1.6 no signal
194 Impaired Gastric Emptying 7 1.6 1.6 no signal
195 Crying 20 1.6 1.6 no signal
196 Brain Neoplasm 5 1.5 1.5 no signal
197 Cardiac Failure 43 1.5 1.5 no signal
198 Pulmonary Embolism 51 1.5 1.5 no signal
199 Intestinal Perforation 6 1.5 1.5 no signal
200 Squamous Cell Carcinoma 5 1.5 1.5 no signal
201 Coma 25 1.5 1.5 no signal
202 Musculoskeletal Chest Pain 8 1.5 1.5 no signal
203 Lymphoma 8 1.5 1.5 no signal
204 Pulmonary Oedema 23 1.5 1.5 no signal
205 Spinal Pain 6 1.5 1.5 no signal
206 Peripheral Coldness 7 1.4 1.4 no signal
207 Embedded Device 5 1.4 1.4 no signal
208 Neuroleptic Malignant Syndrome 6 1.4 1.4 no signal
209 Myoclonus 6 1.4 1.4 no signal
210 Bladder Disorder 5 1.4 1.4 no signal
211 Oxygen Saturation Decreased 28 1.4 1.4 no signal
212 Cerebrovascular Accident 84 1.4 1.4 no signal
213 Dry Throat 5 1.4 1.4 no signal
214 Helicobacter Infection 5 1.4 1.4 no signal
215 Back Disorder 8 1.4 1.4 no signal
216 Dizziness 241 1.4 1.4 no signal
217 Arrhythmia 23 1.4 1.4 no signal
218 Muscle Atrophy 6 1.4 1.4 no signal
219 Pallor 13 1.4 1.4 no signal
220 Incorrect Route Of Product Administration 8 1.4 1.4 no signal
221 Foot Fracture 9 1.3 1.3 no signal
222 Injection Site Erythema 58 1.3 1.3 no signal
223 Hyperhidrosis 60 1.3 1.3 no signal
224 Musculoskeletal Discomfort 8 1.3 1.3 no signal
225 Vertigo 28 1.3 1.3 no signal
226 Injection Site Reaction 31 1.3 1.3 no signal
227 Device Leakage 19 1.3 1.3 no signal
228 Suicide Attempt 27 1.3 1.3 no signal
229 Memory Impairment 61 1.3 1.3 no signal
230 Skin Irritation 20 1.2 1.2 no signal
231 Gastrointestinal Carcinoma 4 1.2 1.2 no signal
232 Muscle Twitching 10 1.2 1.2 no signal
233 Spinal Disorder 4 1.2 1.2 no signal
234 Lower Limb Fracture 8 1.2 1.2 no signal
235 Wrong Technique In Device Usage Process 19 1.2 1.2 no signal
236 Nervous System Disorder 13 1.2 1.2 no signal
237 Affect Lability 4 1.2 1.2 no signal
238 Anger 14 1.2 1.2 no signal
239 Intentional Self-injury 8 1.1 1.1 no signal
240 Eye Discharge 4 1.1 1.1 no signal
241 Euphoric Mood 4 1.1 1.1 no signal
242 Illness 39 1.1 1.1 no signal
243 Product Use Complaint 6 1.1 1.1 no signal
244 Complication Associated With Device 5 1.1 1.1 no signal
245 Ocular Discomfort 4 1.0 1.0 no signal
246 Mood Altered 10 1.0 1.0 no signal
247 Generalised Tonic-clonic Seizure 6 1.0 1.0 no signal
248 Feeling Jittery 7 1.0 1.0 no signal
249 Rash Papular 8 1.0 1.0 no signal
250 Product Administration Error 7 1.0 1.0 no signal
251 Injection Site Warmth 7 1.0 1.0 no signal
252 Meningioma 5 1.0 1.0 no signal
253 Colon Cancer 5 1.0 1.0 no signal
254 Device Adhesion Issue 5 0.9 0.9 no signal
255 Skin Cancer 7 0.9 0.9 no signal
256 Injection Site Discolouration 4 0.9 0.9 no signal
257 Muscle Spasticity 4 0.9 0.9 no signal
258 Underdose 23 0.9 0.9 no signal
259 Device Delivery System Issue 8 0.9 0.9 no signal
260 Incorrect Dose Administered 67 0.8 0.8 no signal
261 Toxic Skin Eruption 3 0.8 0.8 no signal
262 Poor Quality Product Administered 3 0.8 0.8 no signal
263 Injection Site Swelling 22 0.8 0.8 no signal
264 Procedural Pain 8 0.8 0.8 no signal
265 Injection Site Haematoma 4 0.8 0.8 no signal
266 Injection Site Mass 10 0.8 0.8 no signal
267 Emotional Distress 32 0.7 0.7 no signal
268 Internal Haemorrhage 3 0.7 0.7 no signal
269 Myocardial Infarction 44 0.7 0.7 no signal
270 Schizophrenia 3 0.7 0.7 no signal
271 Needle Issue 7 0.7 0.7 no signal
272 Multiple Fractures 4 0.7 0.7 no signal
273 Pancreatic Carcinoma 7 0.7 0.7 no signal
274 Syringe Issue 4 0.6 0.6 no signal
275 Serotonin Syndrome 4 0.6 0.6 no signal
276 Breast Cancer Female 5 0.5 0.5 no signal
277 Injection Site Bruising 14 0.5 0.5 no signal
278 Prostate Cancer 14 0.5 0.5 no signal
279 Injection Site Pain 47 0.4 0.4 no signal
280 Extra Dose Administered 6 0.4 0.4 no signal
281 Completed Suicide 12 0.4 0.4 no signal
282 Injection Site Haemorrhage 11 0.4 0.4 no signal
283 Bladder Cancer 8 0.4 0.4 no signal
284 Incorrect Dose Administered By Device 3 0.3 0.3 no signal
285 Gastric Cancer 3 0.3 0.3 no signal
286 Drug Abuse 7 0.2 0.2 no signal
287 Drug Dose Omission By Device 3 0.1 0.1 no signal