OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Hydroxyurea

1,172 flagged reaction(s) · 80,649 total co-reports · max PRR 393.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Granulomatous Rosacea 14 393.3 393.6 signal
2 Acute Chest Syndrome 174 248.0 250.0 signal
3 Angiodermatitis 15 210.7 210.9 signal
4 Differentiation Syndrome 100 162.3 163.0 signal
5 Essential Thrombocythaemia 45 140.5 140.8 signal
6 Leukostasis Syndrome 15 131.7 131.8 signal
7 Primary Myelofibrosis 32 112.0 112.1 signal
8 Nail Pigmentation 23 104.7 104.8 signal
9 Sickle Cell Anaemia With Crisis 1,485 103.5 111.3 signal
10 Sickle Cell Disease 41 97.6 97.8 signal
11 Myelofibrosis 269 97.2 98.5 signal
12 Myeloproliferative Neoplasm 50 82.5 82.7 signal
13 Polycythaemia Vera 56 73.8 74.0 signal
14 Hyperleukocytosis 58 70.8 71.0 signal
15 Sickle Cell Anaemia 39 63.5 63.6 signal
16 Blast Crisis In Myelogenous Leukaemia 74 63.4 63.7 signal
17 Erythromelalgia 20 57.0 57.1 signal
18 Blast Cell Count Increased 56 56.1 56.3 signal
19 Platelet Count Increased 647 51.9 53.6 signal
20 Cytogenetic Analysis Abnormal 52 51.8 51.9 signal
21 Philadelphia Chromosome Positive 33 48.1 48.2 signal
22 Bone Marrow Reticulin Fibrosis 12 47.6 47.6 signal
23 Chronic Myeloid Leukaemia Transformation 20 46.8 46.9 signal
24 Transformation To Acute Myeloid Leukaemia 29 46.0 46.1 signal
25 Erythropoiesis Abnormal 12 40.8 40.9 signal
26 Hypersplenism 19 39.9 40.0 signal
27 Splenomegaly 430 38.0 38.8 signal
28 Chronic Myelomonocytic Leukaemia 24 37.3 37.3 signal
29 Myeloid Leukaemia 18 36.8 36.8 signal
30 Chronic Myeloid Leukaemia 162 36.2 36.4 signal
31 Chronic Myeloid Leukaemia Recurrent 19 35.8 35.8 signal
32 Thrombocytosis 125 35.3 35.5 signal
33 Marrow Hyperplasia 22 32.9 33.0 signal
34 Antineutrophil Cytoplasmic Antibody Positive 23 32.5 32.5 signal
35 Haematocrit Increased 69 31.1 31.2 signal
36 Thrombocythaemia 16 29.4 29.4 signal
37 Blast Cells Present 13 27.8 27.8 signal
38 Reticulocyte Count Increased 22 27.8 27.8 signal
39 Myelodysplastic Syndrome Transformation 14 27.3 27.3 signal
40 Blood Iron Increased 49 26.6 26.7 signal
41 Splenic Infarction 45 26.5 26.6 signal
42 Serum Ferritin Increased 136 26.5 26.7 signal
43 Haematocrit Abnormal 32 26.5 26.5 signal
44 Actinic Keratosis 66 25.8 25.9 signal
45 Full Blood Count Increased 30 25.7 25.7 signal
46 Anisocytosis 15 23.6 23.6 signal
47 Spleen Disorder 39 23.4 23.4 signal
48 Acute Leukaemia 37 23.3 23.3 signal
49 Acute Myeloid Leukaemia 348 22.8 23.2 signal
50 Increased Viscosity Of Upper Respiratory Secretion 16 21.6 21.6 signal
51 Graft Versus Host Disease In Skin 46 21.3 21.3 signal
52 Basophil Count Increased 15 20.3 20.3 signal
53 Red Blood Cell Count Increased 54 19.8 19.8 signal
54 Alpha Haemolytic Streptococcal Infection 18 19.7 19.7 signal
55 Platelet Count Abnormal 116 19.5 19.7 signal
56 Tumour Lysis Syndrome 168 19.5 19.7 signal
57 Iron Overload 19 17.8 17.9 signal
58 Acute Myeloid Leukaemia Recurrent 37 17.6 17.6 signal
59 Red Blood Cell Count Abnormal 24 16.6 16.6 signal
60 Haemoglobin Increased 73 16.4 16.5 signal
61 White Blood Cell Count Increased 594 15.6 16.0 signal
62 Extremity Necrosis 27 15.6 15.6 signal
63 Squamous Cell Carcinoma Of Skin 90 15.1 15.2 signal
64 Parainfluenzae Virus Infection 23 15.0 15.0 signal
65 Ureterolithiasis 15 14.5 14.5 signal
66 Chronic Graft Versus Host Disease In Skin 13 14.4 14.4 signal
67 Leukaemia Recurrent 24 14.3 14.4 signal
68 Packed Red Blood Cell Transfusion 19 14.3 14.3 signal
69 Anaemia Macrocytic 30 14.3 14.3 signal
70 Nail Discolouration 55 14.2 14.2 signal
71 Leukocytosis 250 14.0 14.1 signal
72 Squamous Cell Carcinoma 129 13.8 13.9 signal
73 Cytomegalovirus Infection Reactivation 58 13.7 13.8 signal
74 Hepatosplenomegaly 35 13.7 13.7 signal
75 Platelet Disorder 34 13.6 13.6 signal
76 Graft Versus Host Disease In Gastrointestinal Tract 28 13.3 13.3 signal
77 Trisomy 21 16 12.7 12.7 signal
78 Transplant Failure 30 12.4 12.4 signal
79 Dermatomyositis 31 12.3 12.3 signal
80 Mean Cell Volume Increased 30 11.8 11.8 signal
81 Blood Lactate Dehydrogenase Increased 184 11.6 11.7 signal
82 Skin Ulcer 291 11.4 11.5 signal
83 Macrocytosis 13 11.2 11.2 signal
84 Blood Uric Acid Increased 62 10.8 10.9 signal
85 Differential White Blood Cell Count Abnormal 18 10.7 10.7 signal
86 Hyperphosphataemia 22 10.5 10.5 signal
87 Jugular Vein Thrombosis 18 10.3 10.3 signal
88 Platelet Transfusion 13 10.2 10.2 signal
89 Adenovirus Infection 29 10.2 10.2 signal
90 Tongue Neoplasm Malignant Stage Unspecified 17 10.1 10.1 signal
91 Early Satiety 19 10.0 10.0 signal
92 Bone Marrow Disorder 30 10.0 10.0 signal
93 Acute Febrile Neutrophilic Dermatosis 23 10.0 10.0 signal
94 White Blood Cell Count Abnormal 63 10.0 10.0 signal
95 Blood Count Abnormal 152 9.9 10.0 signal
96 Haemoglobin Abnormal 63 9.9 9.9 signal
97 Splenic Rupture 16 9.8 9.8 signal
98 Stenotrophomonas Infection 13 9.8 9.8 signal
99 White Blood Cell Disorder 25 9.4 9.4 signal
100 Acute Graft Versus Host Disease In Intestine 13 9.3 9.3 signal
101 Second Primary Malignancy 77 9.3 9.3 signal
102 Haemoglobin Decreased 939 9.2 9.6 signal
103 Gene Mutation 18 9.1 9.1 signal
104 Hyperuricaemia 36 8.8 8.8 signal
105 Haematocrit Decreased 175 8.8 8.9 signal
106 Neutropenic Colitis 18 8.8 8.8 signal
107 Leukaemia 82 8.7 8.8 signal
108 Acute Graft Versus Host Disease In Skin 24 8.7 8.7 signal
109 Full Blood Count Abnormal 89 8.5 8.5 signal
110 Venoocclusive Disease 21 8.4 8.4 signal
111 Red Blood Cell Count Decreased 236 8.3 8.4 signal
112 Acute Graft Versus Host Disease 37 8.0 8.1 signal
113 Bone Marrow Transplant 15 8.0 8.0 signal
114 Enterococcal Infection 38 7.9 7.9 signal
115 Priapism 27 7.8 7.8 signal
116 Bilirubin Conjugated Increased 18 7.8 7.8 signal
117 Pruritus Genital 18 7.8 7.8 signal
118 Soft Tissue Infection 14 7.8 7.8 signal
119 Serum Ferritin Decreased 13 7.6 7.6 signal
120 Aplasia 15 7.5 7.5 signal
121 Portal Vein Thrombosis 24 7.5 7.5 signal
122 Monocyte Count Increased 26 7.2 7.2 signal
123 Idiopathic Intracranial Hypertension 16 7.1 7.1 signal
124 Lung Consolidation 20 7.1 7.1 signal
125 Graft Versus Host Disease 51 7.1 7.1 signal
126 Red Cell Distribution Width Increased 29 7.0 7.0 signal
127 Acute Lymphocytic Leukaemia Recurrent 18 7.0 7.0 signal
128 Cytopenia 83 7.0 7.0 signal
129 Bacterial Sepsis 22 6.8 6.8 signal
130 Varices Oesophageal 20 6.6 6.7 signal
131 Platelet Count Decreased 696 6.6 6.7 signal
132 Mixed Liver Injury 19 6.5 6.6 signal
133 Tongue Ulceration 22 6.5 6.5 signal
134 Pneumonia Fungal 25 6.5 6.5 signal
135 Febrile Neutropenia 426 6.5 6.6 signal
136 Myelodysplastic Syndrome 93 6.4 6.5 signal
137 Polycythaemia 13 6.4 6.4 signal
138 Basal Cell Carcinoma 99 6.4 6.4 signal
139 Aplastic Anaemia 33 6.3 6.3 signal
140 Hepatomegaly 62 6.3 6.3 signal
141 Pulmonary Alveolar Haemorrhage 35 6.3 6.3 signal
142 Blood Disorder 50 6.3 6.3 signal
143 Transfusion 65 6.2 6.2 signal
144 Subdural Haemorrhage 17 6.2 6.2 signal
145 Posterior Reversible Encephalopathy Syndrome 58 6.1 6.1 signal
146 Emergency Care 18 6.1 6.1 signal
147 Chronic Graft Versus Host Disease 22 6.1 6.1 signal
148 Mucosal Inflammation 156 6.0 6.0 signal
149 Bronchopulmonary Aspergillosis 46 6.0 6.0 signal
150 Ventricular Hypokinesia 19 5.9 5.9 signal
151 Pancytopenia 326 5.9 5.9 signal
152 Increased Tendency To Bruise 53 5.8 5.8 signal
153 Neutrophil Count Increased 59 5.8 5.8 signal
154 Disseminated Intravascular Coagulation 81 5.7 5.8 signal
155 Stem Cell Transplant 14 5.7 5.7 signal
156 Foetal Growth Restriction 34 5.6 5.6 signal
157 Discouragement 13 5.6 5.6 signal
158 Fibrosis 17 5.5 5.5 signal
159 Bone Marrow Failure 113 5.5 5.6 signal
160 Anaemia 1,045 5.5 5.7 signal
161 Lung Infiltration 48 5.4 5.4 signal
162 Blood Loss Anaemia 12 5.4 5.4 signal
163 Thrombocytopenia 599 5.4 5.5 signal
164 Cytolytic Hepatitis 18 5.4 5.4 signal
165 Hyperbilirubinaemia 55 5.3 5.4 signal
166 Haemolysis 41 5.3 5.3 signal
167 Hypersensitivity Vasculitis 14 5.3 5.3 signal
168 Escherichia Bacteraemia 12 5.2 5.2 signal
169 Product Availability Issue 116 5.2 5.2 signal
170 Acute Respiratory Failure 99 5.2 5.2 signal
171 Multiple-drug Resistance 16 5.2 5.2 signal
172 Hepatitis Fulminant 15 5.1 5.1 signal
173 Haemorrhagic Diathesis 18 5.0 5.0 signal
174 Concomitant Disease Aggravated 31 5.0 5.0 signal
175 Normal Newborn 27 5.0 5.0 signal
176 Iron Deficiency 22 5.0 5.0 signal
177 Coronavirus Infection 33 5.0 5.0 signal
178 Wound Complication 17 4.9 4.9 signal
179 Blood Iron Decreased 58 4.9 4.9 signal
180 Carotid Artery Occlusion 18 4.9 4.9 signal
181 Epstein-barr Virus Infection 30 4.8 4.8 signal
182 Full Blood Count Decreased 97 4.8 4.8 signal
183 Subdural Haematoma 69 4.8 4.8 signal
184 Night Sweats 154 4.8 4.8 signal
185 Skin Hyperpigmentation 41 4.8 4.8 signal
186 Klebsiella Infection 24 4.8 4.8 signal
187 Product Use Complaint 74 4.8 4.8 signal
188 Drug Resistance 122 4.8 4.8 signal
189 Pigmentation Disorder 29 4.7 4.7 signal
190 Cachexia 24 4.7 4.7 signal
191 Brain Herniation 14 4.7 4.7 signal
192 Portal Hypertension 14 4.5 4.5 signal
193 Bk Virus Infection 15 4.5 4.5 signal
194 Pulmonary Haemorrhage 35 4.5 4.5 signal
195 Venoocclusive Liver Disease 22 4.5 4.5 signal
196 Blood Bilirubin Increased 120 4.4 4.5 signal
197 Laryngitis 48 4.4 4.4 signal
198 Acute Respiratory Distress Syndrome 77 4.4 4.4 signal
199 Nasal Polyps 21 4.4 4.4 signal
200 Haemolytic Anaemia 39 4.3 4.3 signal
201 Ulcer 69 4.3 4.3 signal
202 Pulmonary Hypertension 90 4.3 4.3 signal
203 Vasculitis 50 4.3 4.3 signal
204 Gangrene 26 4.3 4.3 signal
205 Flank Pain 40 4.3 4.3 signal
206 Acute Lymphocytic Leukaemia 12 4.2 4.2 signal
207 Neutrophilia 24 4.2 4.2 signal
208 Ocular Icterus 18 4.2 4.2 signal
209 Escherichia Sepsis 12 4.2 4.2 signal
210 Pericardial Effusion 95 4.1 4.1 signal
211 Skin Cancer 88 4.1 4.1 signal
212 Aortic Stenosis 14 4.0 4.0 signal
213 Decreased Activity 43 4.0 4.0 signal
214 Pleural Effusion 244 4.0 4.0 signal
215 Bacteraemia 47 4.0 4.0 signal
216 Muscle Haemorrhage 16 4.0 4.0 signal
217 Blood Urea Increased 67 4.0 4.0 signal
218 Embolism Venous 12 4.0 4.0 signal
219 Cerebrovascular Disorder 12 3.9 3.9 signal
220 Blood Alkaline Phosphatase Increased 97 3.9 3.9 signal
221 Blood Potassium Increased 63 3.9 3.9 signal
222 Cerebral Haematoma 13 3.9 3.9 signal
223 Febrile Bone Marrow Aplasia 16 3.8 3.8 signal
224 Left Ventricular Failure 13 3.8 3.8 signal
225 Endocarditis 19 3.7 3.7 signal
226 Product Dose Omission 242 3.7 3.7 signal
227 Haemorrhage Subcutaneous 13 3.7 3.7 signal
228 Rales 21 3.6 3.6 signal
229 Skin Mass 24 3.6 3.6 signal
230 Left Ventricular Dysfunction 24 3.6 3.6 signal
231 Immunodeficiency 53 3.6 3.6 signal
232 Cardiac Murmur 31 3.6 3.6 signal
233 Energy Increased 21 3.5 3.5 signal
234 Clostridium Difficile Colitis 37 3.5 3.5 signal
235 Skin Necrosis 18 3.5 3.5 signal
236 Cytomegalovirus Viraemia 15 3.4 3.4 signal
237 International Normalised Ratio Decreased 14 3.4 3.4 signal
238 Rhinovirus Infection 13 3.4 3.4 signal
239 Peripheral Arterial Occlusive Disease 14 3.4 3.4 signal
240 Lipase Increased 26 3.4 3.4 signal
241 Mouth Haemorrhage 25 3.4 3.4 signal
242 Conjunctival Haemorrhage 13 3.4 3.4 signal
243 Cardiomegaly 42 3.4 3.4 signal
244 Glossitis 12 3.4 3.4 signal
245 Cytomegalovirus Infection 56 3.4 3.4 signal
246 Hydronephrosis 25 3.3 3.4 signal
247 Gout 60 3.3 3.3 signal
248 Phlebitis 17 3.3 3.3 signal
249 Cardiac Failure Acute 22 3.3 3.3 signal
250 Haematoma 86 3.3 3.3 signal
251 Epistaxis 247 3.3 3.3 signal
252 White Blood Cell Count Decreased 357 3.3 3.3 signal
253 Peripheral Vascular Disorder 17 3.3 3.3 signal
254 Blood Test Abnormal 46 3.3 3.3 signal
255 Therapy Non-responder 145 3.3 3.3 signal
256 Cerebral Atrophy 13 3.2 3.2 signal
257 Generalised Oedema 40 3.2 3.3 signal
258 Hypomagnesaemia 45 3.2 3.2 signal
259 Cystitis Haemorrhagic 13 3.2 3.2 signal
260 Staphylococcal Bacteraemia 14 3.2 3.2 signal
261 Creatinine Renal Clearance Decreased 13 3.2 3.2 signal
262 Dyspnoea Exertional 121 3.2 3.2 signal
263 Oliguria 20 3.2 3.2 signal
264 Cholestasis 61 3.2 3.2 signal
265 Pseudomonas Infection 27 3.2 3.2 signal
266 Mouth Ulceration 67 3.2 3.2 signal
267 Pleurisy 19 3.2 3.2 signal
268 Insurance Issue 47 3.2 3.2 signal
269 Blood Albumin Decreased 25 3.2 3.2 signal
270 Haemorrhagic Anaemia 14 3.1 3.1 signal
271 Contusion 300 3.1 3.1 signal
272 Multiple Organ Dysfunction Syndrome 87 3.1 3.1 signal
273 Intentional Product Use Issue 274 3.1 3.1 signal
274 Electrocardiogram Qt Prolonged 112 3.1 3.1 signal
275 Interstitial Lung Disease 149 3.1 3.1 signal
276 Hyperkeratosis 17 3.1 3.1 signal
277 No Therapeutic Response 38 3.1 3.1 signal
278 Therapy Cessation 156 3.1 3.1 signal
279 Bone Pain 179 3.1 3.1 signal
280 Cerebral Haemorrhage 108 3.0 3.0 signal
281 Laboratory Test Abnormal 89 3.0 3.0 signal
282 Pyelonephritis 26 3.0 3.0 signal
283 Product Size Issue 16 3.0 3.0 signal
284 Gingival Bleeding 41 3.0 3.0 signal
285 Aphthous Ulcer 23 3.0 3.0 signal
286 Transplant Rejection 24 3.0 3.0 signal
287 Gastrointestinal Toxicity 14 3.0 3.0 signal
288 Erysipelas 15 3.0 3.0 signal
289 Retinal Haemorrhage 21 3.0 3.0 signal
290 Activated Partial Thromboplastin Time Prolonged 15 2.9 3.0 signal
291 Cerebral Infarction 72 2.9 2.9 signal
292 Cardiac Tamponade 14 2.9 2.9 signal
293 Escherichia Infection 24 2.9 2.9 signal
294 Haemorrhage Intracranial 44 2.9 2.9 signal
295 Product Dose Omission Issue 833 2.9 3.0 signal
296 Intestinal Ischaemia 16 2.9 2.9 signal
297 Ecchymosis 20 2.9 2.9 signal
298 Pulmonary Mass 43 2.9 2.9 signal
299 Jaundice 78 2.9 2.9 signal
300 Lymphocyte Count Decreased 51 2.9 2.9 signal
301 Pulmonary Arterial Hypertension 42 2.9 2.9 signal
302 Toxic Skin Eruption 29 2.9 2.9 signal
303 Hypoxia 100 2.8 2.9 signal
304 Pulmonary Toxicity 20 2.8 2.8 signal
305 Hypernatraemia 14 2.8 2.8 signal
306 Septic Shock 121 2.8 2.8 signal
307 Nephrogenic Anaemia 13 2.8 2.8 signal
308 Herpes Simplex 18 2.8 2.8 signal
309 Dermatitis Exfoliative 14 2.8 2.8 signal
310 Urine Output Decreased 24 2.7 2.7 signal
311 Mitral Valve Incompetence 31 2.7 2.7 signal
312 Lung Infection 43 2.7 2.7 signal
313 Partial Seizures 14 2.7 2.7 signal
314 Increased Appetite 51 2.7 2.7 signal
315 Malnutrition 30 2.7 2.7 signal
316 Periorbital Oedema 14 2.7 2.7 signal
317 Renal Failure Chronic 21 2.7 2.7 signal
318 Blood Creatinine Increased 176 2.7 2.7 signal
319 Pyrexia 929 2.7 2.8 signal
320 Impaired Healing 88 2.7 2.7 signal
321 Respiratory Distress 74 2.7 2.7 signal
322 Sepsis 298 2.7 2.7 signal
323 Stomatitis 162 2.7 2.7 signal
324 Staphylococcal Infection 88 2.7 2.7 signal
325 Angiopathy 15 2.7 2.7 signal
326 Hepatitis B 16 2.6 2.6 signal
327 Pneumonia Bacterial 24 2.6 2.6 signal
328 Enterocolitis 15 2.6 2.6 signal
329 Staphylococcal Sepsis 13 2.6 2.6 signal
330 Skin Atrophy 15 2.6 2.6 signal
331 Myocardial Ischaemia 30 2.6 2.6 signal
332 Oral Candidiasis 34 2.6 2.6 signal
333 Anal Abscess 14 2.6 2.6 signal
334 Bundle Branch Block Right 12 2.6 2.6 signal
335 Aspartate Aminotransferase Increased 138 2.6 2.6 signal
336 Post Transplant Lymphoproliferative Disorder 13 2.6 2.6 signal
337 Toxic Epidermal Necrolysis 39 2.6 2.6 signal
338 Respiratory Failure 188 2.6 2.6 signal
339 Melaena 56 2.5 2.5 signal
340 Terminal State 17 2.5 2.5 signal
341 Cholelithiasis 83 2.5 2.5 signal
342 Off Label Use 2,188 2.5 2.7 signal
343 Transaminases Increased 56 2.5 2.5 signal
344 Hepatitis Cholestatic 15 2.5 2.5 signal
345 Petechiae 26 2.5 2.5 signal
346 Viral Infection 83 2.5 2.5 signal
347 Acute Pulmonary Oedema 14 2.5 2.5 signal
348 Faeces Soft 18 2.5 2.5 signal
349 Prothrombin Time Prolonged 15 2.5 2.5 signal
350 Onychoclasis 17 2.5 2.5 signal
351 Anal Incontinence 22 2.5 2.5 signal
352 Cardiac Failure 196 2.4 2.5 signal
353 Hospice Care 24 2.4 2.4 signal
354 Cardiomyopathy 36 2.4 2.4 signal
355 Immunosuppression 21 2.4 2.4 signal
356 Ventricular Extrasystoles 25 2.4 2.4 signal
357 Peripheral Sensory Neuropathy 14 2.4 2.4 signal
358 Blood Calcium Decreased 27 2.4 2.4 signal
359 Pneumonia 768 2.4 2.4 signal
360 Purpura 21 2.4 2.4 signal
361 Treatment Noncompliance 129 2.4 2.4 signal
362 Hepatic Function Abnormal 88 2.4 2.4 signal
363 Atelectasis 23 2.4 2.4 signal
364 Abdominal Discomfort 396 2.4 2.4 signal
365 Pulmonary Oedema 105 2.3 2.3 signal
366 Drug Intolerance 225 2.3 2.3 signal
367 Multi-organ Failure 41 2.3 2.3 signal
368 Skin Infection 26 2.3 2.3 signal
369 Necrosis 13 2.3 2.3 signal
370 Abdominal Pain Upper 476 2.3 2.3 signal
371 Cardiac Flutter 15 2.3 2.3 signal
372 Ejection Fraction Decreased 36 2.3 2.3 signal
373 Hepatic Steatosis 43 2.3 2.3 signal
374 Respiratory Syncytial Virus Infection 20 2.3 2.3 signal
375 Leukopenia 115 2.3 2.3 signal
376 Failure To Thrive 12 2.3 2.3 signal
377 Blood Sodium Decreased 43 2.3 2.3 signal
378 Disease Progression 268 2.3 2.3 signal
379 Bacterial Infection 42 2.3 2.3 signal
380 Renal Impairment 189 2.3 2.3 signal
381 Haematemesis 57 2.2 2.2 signal
382 Renal Tubular Necrosis 22 2.2 2.2 signal
383 Glomerular Filtration Rate Decreased 27 2.2 2.2 signal
384 Hypokalaemia 102 2.2 2.2 signal
385 Oedema Peripheral 271 2.2 2.2 signal
386 Shock Haemorrhagic 18 2.2 2.2 signal
387 Maternal Exposure Before Pregnancy 15 2.2 2.2 signal
388 Faecaloma 12 2.2 2.2 signal
389 Pneumocystis Jirovecii Pneumonia 22 2.2 2.2 signal
390 Malignant Neoplasm Progression 224 2.2 2.2 signal
391 Diarrhoea 1,408 2.2 2.3 signal
392 Nephrotic Syndrome 15 2.2 2.2 signal
393 Lymphoedema 15 2.2 2.2 signal
394 Decreased Appetite 503 2.2 2.2 signal
395 Sleep Disorder Due To A General Medical Condition 35 2.2 2.2 signal
396 Product Dose Omission In Error 58 2.2 2.2 signal
397 Blood Pressure Diastolic Decreased 16 2.2 2.2 signal
398 Haematotoxicity 20 2.2 2.2 signal
399 Subarachnoid Haemorrhage 22 2.2 2.2 signal
400 Tricuspid Valve Incompetence 17 2.1 2.1 signal
401 Skin Haemorrhage 31 2.1 2.1 signal
402 Post Procedural Haemorrhage 25 2.1 2.1 signal
403 Diarrhoea Haemorrhagic 20 2.1 2.1 signal
404 Skin Lesion 58 2.1 2.1 signal
405 Duodenal Ulcer 15 2.1 2.1 signal
406 Neutropenia 288 2.1 2.1 signal
407 Hyperkalaemia 74 2.1 2.1 signal
408 Osteonecrosis 70 2.1 2.1 signal
409 Rhinitis 17 2.1 2.1 signal
410 Exercise Tolerance Decreased 12 2.1 2.1 signal
411 Liver Disorder 93 2.1 2.1 signal
412 Neutrophil Count Decreased 85 2.1 2.1 signal
413 Rash Maculo-papular 46 2.1 2.1 signal
414 Haemorrhage 217 2.1 2.1 signal
415 Musculoskeletal Chest Pain 32 2.1 2.1 signal
416 Premature Delivery 33 2.1 2.1 signal
417 Cellulitis 104 2.1 2.1 signal
418 Lymphopenia 29 2.1 2.1 signal
419 Hypertransaminasaemia 14 2.1 2.1 signal
420 Abdominal Pain 477 2.0 2.1 signal
421 Therapy Interrupted 141 2.0 2.0 signal
422 Haemorrhagic Stroke 16 2.0 2.0 signal
423 Asthenia 757 2.0 2.0 signal
424 Skin Discolouration 92 2.0 2.0 no signal
425 Haemodynamic Instability 15 2.0 2.0 no signal
426 Oedema 108 2.0 2.0 no signal
427 Chromaturia 45 2.0 2.0 no signal
428 Fatigue 1,547 2.0 2.1 no signal
429 Troponin Increased 15 2.0 2.0 no signal
430 Hepatic Failure 60 2.0 2.0 no signal
431 Gamma-glutamyltransferase Increased 44 2.0 2.0 no signal
432 Pathogen Resistance 18 2.0 2.0 no signal
433 Transient Ischaemic Attack 67 2.0 2.0 no signal
434 Gastrointestinal Haemorrhage 166 2.0 2.0 no signal
435 Thrombosis 159 2.0 2.0 no signal
436 Renal Disorder 92 2.0 2.0 no signal
437 Sluggishness 20 2.0 2.0 no signal
438 Myelosuppression 67 2.0 2.0 no signal
439 Blood Magnesium Decreased 17 2.0 2.0 no signal
440 Fluid Retention 100 2.0 2.0 no signal
441 Nail Disorder 17 2.0 2.0 no signal
442 Renal Failure Acute 84 1.9 2.0 no signal
443 Dehydration 260 1.9 2.0 no signal
444 Pulmonary Embolism 186 1.9 2.0 no signal
445 Dermatitis Bullous 14 1.9 1.9 no signal
446 Skin Laceration 21 1.9 1.9 no signal
447 Decreased Immune Responsiveness 19 1.9 1.9 no signal
448 Tuberculosis 25 1.9 1.9 no signal
449 Mental Status Changes 54 1.9 1.9 no signal
450 Hepatotoxicity 43 1.9 1.9 no signal
451 Alanine Aminotransferase Increased 118 1.9 1.9 no signal
452 Tachypnoea 26 1.9 1.9 no signal
453 Acute Coronary Syndrome 16 1.9 1.9 no signal
454 General Physical Condition Abnormal 13 1.9 1.9 no signal
455 Hepatic Cytolysis 23 1.9 1.9 no signal
456 Infarction 13 1.9 1.9 no signal
457 Flatulence 106 1.9 1.9 no signal
458 Eating Disorder 40 1.9 1.9 no signal
459 Cholecystitis 22 1.8 1.8 no signal
460 Iron Deficiency Anaemia 17 1.8 1.8 no signal
461 Faeces Discoloured 40 1.8 1.8 no signal
462 Appetite Disorder 12 1.8 1.8 no signal
463 Wound Infection 20 1.8 1.8 no signal
464 Ascites 54 1.8 1.8 no signal
465 Lymphadenopathy 65 1.8 1.8 no signal
466 Hyponatraemia 103 1.8 1.8 no signal
467 Hypoalbuminaemia 14 1.8 1.8 no signal
468 Fluid Overload 27 1.8 1.8 no signal
469 Hepatocellular Injury 26 1.8 1.8 no signal
470 Haemoptysis 51 1.8 1.8 no signal
471 Brain Oedema 23 1.8 1.8 no signal
472 Tenderness 19 1.8 1.8 no signal
473 Neutropenic Sepsis 13 1.8 1.8 no signal
474 Pulmonary Congestion 24 1.8 1.8 no signal
475 Herpes Zoster 104 1.8 1.8 no signal
476 Product Distribution Issue 16 1.8 1.8 no signal
477 Oral Discomfort 25 1.8 1.8 no signal
478 Dementia 50 1.8 1.8 no signal
479 Spinal Pain 21 1.8 1.8 no signal
480 Drug Administered To Patient Of Inappropriate Age 13 1.8 1.8 no signal
481 Spinal Compression Fracture 15 1.8 1.8 no signal
482 Gastric Ulcer 34 1.8 1.8 no signal
483 Dysphagia 169 1.8 1.8 no signal
484 Brain Fog 26 1.8 1.8 no signal
485 Torsade De Pointes 14 1.8 1.8 no signal
486 Supraventricular Tachycardia 17 1.8 1.8 no signal
487 Liver Function Test Abnormal 52 1.8 1.8 no signal
488 Rash Pustular 13 1.8 1.8 no signal
489 Temperature Intolerance 18 1.8 1.8 no signal
490 Blood Potassium Decreased 53 1.8 1.8 no signal
491 Abdominal Distension 183 1.8 1.8 no signal
492 Renal Cyst 14 1.8 1.8 no signal
493 Hepatitis 45 1.8 1.8 no signal
494 Constipation 380 1.8 1.8 no signal
495 Pain In Extremity 518 1.8 1.8 no signal
496 Infection 251 1.7 1.7 no signal
497 Pericarditis 29 1.7 1.7 no signal
498 Pneumonitis 47 1.7 1.7 no signal
499 Limb Injury 47 1.7 1.7 no signal
500 Anuria 15 1.7 1.7 no signal
501 Atrial Fibrillation 169 1.7 1.7 no signal
502 C-reactive Protein Increased 63 1.7 1.7 no signal
503 Poor Quality Sleep 37 1.7 1.7 no signal
504 Acute Kidney Injury 263 1.7 1.7 no signal
505 Premature Baby 52 1.7 1.7 no signal
506 Eye Haemorrhage 23 1.7 1.7 no signal
507 Hyperthermia 13 1.7 1.7 no signal
508 Decubitus Ulcer 14 1.7 1.7 no signal
509 Back Pain 399 1.7 1.7 no signal
510 General Physical Health Deterioration 197 1.7 1.7 no signal
511 Cardiac Failure Congestive 139 1.7 1.7 no signal
512 Gastritis 45 1.7 1.7 no signal
513 Polyuria 14 1.7 1.7 no signal
514 Headache 1,067 1.7 1.7 no signal
515 Hemiparesis 29 1.7 1.7 no signal
516 Ill-defined Disorder 103 1.7 1.7 no signal
517 Feeling Cold 47 1.7 1.7 no signal
518 Joint Injury 36 1.7 1.7 no signal
519 Emphysema 17 1.7 1.7 no signal
520 Scab 19 1.7 1.7 no signal
521 Therapeutic Response Unexpected 75 1.7 1.7 no signal
522 Haematuria 57 1.7 1.7 no signal
523 Internal Haemorrhage 19 1.7 1.7 no signal
524 Weight Increased 369 1.7 1.7 no signal
525 Wound 46 1.7 1.7 no signal
526 Nausea 1,305 1.7 1.7 no signal
527 Sinus Bradycardia 16 1.6 1.6 no signal
528 Hypersomnia 47 1.6 1.6 no signal
529 Frequent Bowel Movements 44 1.6 1.6 no signal
530 Vitamin D Decreased 14 1.6 1.6 no signal
531 Chest Pain 303 1.6 1.6 no signal
532 Oxygen Saturation Decreased 91 1.6 1.6 no signal
533 Seasonal Allergy 23 1.6 1.6 no signal
534 Ventricular Tachycardia 27 1.6 1.6 no signal
535 Coagulopathy 27 1.6 1.6 no signal
536 Ischaemic Stroke 29 1.6 1.6 no signal
537 Pulmonary Fibrosis 31 1.6 1.6 no signal
538 Acute Myocardial Infarction 48 1.6 1.6 no signal
539 Device Related Infection 25 1.6 1.6 no signal
540 Weight Decreased 450 1.6 1.6 no signal
541 Colon Cancer 24 1.6 1.6 no signal
542 Pneumonia Aspiration 40 1.6 1.6 no signal
543 Post Procedural Infection 13 1.6 1.6 no signal
544 Gastroenteritis Viral 29 1.6 1.6 no signal
545 Nephropathy 15 1.6 1.6 no signal
546 Rash Pruritic 86 1.6 1.6 no signal
547 Arteriosclerosis 15 1.6 1.6 no signal
548 Myocarditis 18 1.6 1.6 no signal
549 Fracture 30 1.6 1.6 no signal
550 Laceration 15 1.6 1.6 no signal
551 Diffuse Large B-cell Lymphoma 12 1.6 1.6 no signal
552 Gastrointestinal Infection 14 1.6 1.6 no signal
553 Acidosis 12 1.6 1.6 no signal
554 Ocular Discomfort 17 1.6 1.6 no signal
555 Malignant Melanoma 21 1.6 1.6 no signal
556 Electrolyte Imbalance 18 1.6 1.6 no signal
557 Skin Disorder 52 1.6 1.6 no signal
558 Renal Failure 209 1.6 1.6 no signal
559 Candida Infection 26 1.6 1.6 no signal
560 Urinary Tract Infection 265 1.6 1.6 no signal
561 Wheezing 92 1.6 1.6 no signal
562 Maternal Exposure During Pregnancy 137 1.6 1.6 no signal
563 Lung Disorder 76 1.5 1.6 no signal
564 Retching 33 1.5 1.5 no signal
565 Dialysis 22 1.5 1.5 no signal
566 Cardio-respiratory Arrest 65 1.5 1.5 no signal
567 Oral Herpes 30 1.5 1.5 no signal
568 Respiratory Tract Infection 40 1.5 1.5 no signal
569 Hypophagia 39 1.5 1.5 no signal
570 Caesarean Section 18 1.5 1.5 no signal
571 Anorexia 20 1.5 1.5 no signal
572 Ventricular Fibrillation 17 1.5 1.5 no signal
573 Chills 179 1.5 1.5 no signal
574 Ligament Sprain 15 1.5 1.5 no signal
575 Incontinence 16 1.5 1.5 no signal
576 Ataxia 18 1.5 1.5 no signal
577 Drug Ineffective For Unapproved Indication 84 1.5 1.5 no signal
578 Peripheral Swelling 231 1.5 1.5 no signal
579 Feeding Disorder 30 1.5 1.5 no signal
580 Neoplasm Malignant 100 1.5 1.5 no signal
581 Eosinophilia 26 1.5 1.5 no signal
582 Nephrolithiasis 68 1.5 1.5 no signal
583 Neoplasm Progression 52 1.5 1.5 no signal
584 Upper Gastrointestinal Haemorrhage 25 1.5 1.5 no signal
585 Aspiration 16 1.5 1.5 no signal
586 Face Oedema 25 1.5 1.5 no signal
587 Inappropriate Antidiuretic Hormone Secretion 15 1.5 1.5 no signal
588 Dizziness 733 1.5 1.5 no signal
589 Fungal Infection 49 1.5 1.5 no signal
590 Blood Urine Present 28 1.5 1.5 no signal
591 Cough 411 1.5 1.5 no signal
592 Hypercholesterolaemia 14 1.5 1.5 no signal
593 Oesophagitis 16 1.5 1.5 no signal
594 Therapy Partial Responder 22 1.5 1.5 no signal
595 Agranulocytosis 27 1.5 1.5 no signal
596 Dyspnoea 825 1.5 1.5 no signal
597 Nodule 19 1.5 1.5 no signal
598 Peripheral Coldness 20 1.4 1.4 no signal
599 Lip Dry 13 1.4 1.4 no signal
600 Vomiting 680 1.4 1.5 no signal
601 Gait Inability 48 1.4 1.4 no signal
602 Hypokinesia 21 1.4 1.4 no signal
603 Thrombotic Microangiopathy 14 1.4 1.4 no signal
604 Immune System Disorder 19 1.4 1.4 no signal
605 Gastroenteritis 21 1.4 1.4 no signal
606 Memory Impairment 198 1.4 1.4 no signal
607 Deep Vein Thrombosis 94 1.4 1.4 no signal
608 Cystitis 46 1.4 1.4 no signal
609 Embolism 12 1.4 1.4 no signal
610 Hypocalcaemia 27 1.4 1.4 no signal
611 Covid-19 Pneumonia 17 1.4 1.4 no signal
612 Pallor 39 1.4 1.4 no signal
613 Disease Recurrence 68 1.4 1.4 no signal
614 International Normalised Ratio Increased 41 1.4 1.4 no signal
615 Influenza 159 1.4 1.4 no signal
616 Head Discomfort 25 1.4 1.4 no signal
617 Urinary Incontinence 42 1.4 1.4 no signal
618 Burning Sensation 99 1.4 1.4 no signal
619 Urosepsis 13 1.4 1.4 no signal
620 Malaise 618 1.4 1.4 no signal
621 Localised Infection 34 1.4 1.4 no signal
622 Pain 862 1.4 1.4 no signal
623 Pancreatitis Acute 31 1.4 1.4 no signal
624 Hiatus Hernia 18 1.4 1.4 no signal
625 Therapeutic Product Effect Incomplete 98 1.4 1.4 no signal
626 Cataract 82 1.4 1.4 no signal
627 Osteomyelitis 25 1.4 1.4 no signal
628 Abortion Induced 13 1.4 1.4 no signal
629 Fall 458 1.4 1.4 no signal
630 Spinal Disorder 13 1.4 1.4 no signal
631 Body Temperature Increased 28 1.4 1.4 no signal
632 Loss Of Personal Independence In Daily Activities 65 1.4 1.4 no signal
633 Blood Pressure Abnormal 27 1.4 1.4 no signal
634 Groin Pain 12 1.4 1.4 no signal
635 Vertigo 83 1.4 1.4 no signal
636 Therapeutic Response Decreased 82 1.4 1.4 no signal
637 Mass 19 1.4 1.4 no signal
638 Hepatic Enzyme Increased 92 1.4 1.4 no signal
639 Dizziness Postural 13 1.4 1.4 no signal
640 Muscle Atrophy 17 1.3 1.3 no signal
641 Encephalopathy 33 1.3 1.3 no signal
642 Nephropathy Toxic 15 1.3 1.3 no signal
643 Sinus Tachycardia 19 1.3 1.3 no signal
644 Vitamin D Deficiency 13 1.3 1.3 no signal
645 Hypotension 267 1.3 1.3 no signal
646 Sinus Congestion 18 1.3 1.3 no signal
647 Metabolic Acidosis 42 1.3 1.3 no signal
648 Mydriasis 17 1.3 1.3 no signal
649 Bursitis 16 1.3 1.3 no signal
650 Proteinuria 25 1.3 1.3 no signal
651 Renal Pain 14 1.3 1.3 no signal
652 Haematochezia 73 1.3 1.3 no signal
653 Micturition Urgency 15 1.3 1.3 no signal
654 Pollakiuria 55 1.3 1.3 no signal
655 Angina Pectoris 38 1.3 1.3 no signal
656 Intestinal Obstruction 49 1.3 1.3 no signal
657 Drug Dose Omission 219 1.3 1.3 no signal
658 Lethargy 75 1.3 1.3 no signal
659 Dermatitis 27 1.3 1.3 no signal
660 Dysuria 48 1.3 1.3 no signal
661 Abdominal Pain Lower 33 1.3 1.3 no signal
662 Arthralgia 538 1.3 1.3 no signal
663 Dysstasia 38 1.3 1.3 no signal
664 Hyperglycaemia 47 1.3 1.3 no signal
665 Cardiac Arrest 107 1.3 1.3 no signal
666 Oral Pain 29 1.3 1.3 no signal
667 Pharyngitis 16 1.3 1.3 no signal
668 Dry Throat 13 1.3 1.3 no signal
669 Haemorrhoids 25 1.3 1.3 no signal
670 Cerebrovascular Accident 217 1.3 1.3 no signal
671 Sars-cov-2 Test Positive 17 1.3 1.3 no signal
672 Gastrooesophageal Reflux Disease 102 1.3 1.3 no signal
673 Head Injury 40 1.3 1.3 no signal
674 Quality Of Life Decreased 17 1.3 1.3 no signal
675 Arrhythmia 60 1.3 1.3 no signal
676 Hyperlipidaemia 15 1.2 1.2 no signal
677 Palpitations 146 1.2 1.2 no signal
678 Rash Papular 28 1.2 1.2 no signal
679 Hypertension 263 1.2 1.2 no signal
680 Lung Neoplasm Malignant 51 1.2 1.2 no signal
681 Ear Pain 24 1.2 1.2 no signal
682 Cholecystectomy 14 1.2 1.2 no signal
683 Muscle Spasms 226 1.2 1.2 no signal
684 Myalgia 209 1.2 1.2 no signal
685 Muscular Weakness 139 1.2 1.2 no signal
686 Neoplasm 14 1.2 1.2 no signal
687 Chronic Kidney Disease 93 1.2 1.2 no signal
688 Coordination Abnormal 17 1.2 1.2 no signal
689 Death 1,041 1.2 1.2 no signal
690 Restless Legs Syndrome 22 1.2 1.2 no signal
691 Tooth Extraction 15 1.2 1.2 no signal
692 Bronchitis 89 1.2 1.2 no signal
693 Eyelid Oedema 14 1.2 1.2 no signal
694 Limb Discomfort 37 1.2 1.2 no signal
695 Abortion Spontaneous 48 1.2 1.2 no signal
696 Musculoskeletal Pain 63 1.2 1.2 no signal
697 Hospitalisation 180 1.2 1.2 no signal
698 Hepatic Cirrhosis 22 1.2 1.2 no signal
699 Polyneuropathy 14 1.2 1.2 no signal
700 Pruritus 440 1.2 1.2 no signal
701 Lymphoma 18 1.2 1.2 no signal
702 Neck Pain 65 1.2 1.2 no signal
703 Altered State Of Consciousness 25 1.2 1.2 no signal
704 Rectal Haemorrhage 50 1.2 1.2 no signal
705 Eructation 22 1.2 1.2 no signal
706 Neuralgia 28 1.2 1.2 no signal
707 Somnolence 232 1.2 1.2 no signal
708 Tinnitus 53 1.1 1.1 no signal
709 Weight Fluctuation 12 1.1 1.1 no signal
710 Inflammation 59 1.1 1.1 no signal
711 Upper Respiratory Tract Infection 53 1.1 1.1 no signal
712 Rash Generalised 30 1.1 1.1 no signal
713 Pregnancy 23 1.1 1.1 no signal
714 Blindness Unilateral 16 1.1 1.1 no signal
715 Pneumothorax 18 1.1 1.1 no signal
716 Hypercalcaemia 14 1.1 1.1 no signal
717 Oropharyngeal Pain 105 1.1 1.1 no signal
718 Pancreatitis 60 1.1 1.1 no signal
719 Neuropathy Peripheral 107 1.1 1.1 no signal
720 Drug Interaction 179 1.1 1.1 no signal
721 Metastases To Lung 13 1.1 1.1 no signal
722 Liver Function Test Increased 24 1.1 1.1 no signal
723 Feeling Abnormal 270 1.1 1.1 no signal
724 Sudden Death 12 1.1 1.1 no signal
725 Gastric Haemorrhage 13 1.1 1.1 no signal
726 Dyspepsia 110 1.1 1.1 no signal
727 Cardiogenic Shock 16 1.1 1.1 no signal
728 Abasia 28 1.1 1.1 no signal
729 Rash 484 1.1 1.1 no signal
730 Coronary Artery Disease 34 1.1 1.1 no signal
731 Gastrointestinal Disorder 98 1.1 1.1 no signal
732 Pharyngitis Streptococcal 12 1.1 1.1 no signal
733 Deafness 29 1.1 1.1 no signal
734 Toothache 20 1.1 1.1 no signal
735 Foot Fracture 21 1.1 1.1 no signal
736 Musculoskeletal Discomfort 19 1.1 1.1 no signal
737 Tachycardia 98 1.1 1.1 no signal
738 Product Administration Error 22 1.1 1.1 no signal
739 Pulmonary Thrombosis 12 1.1 1.1 no signal
740 Treatment Failure 90 1.1 1.1 no signal
741 Rash Macular 38 1.1 1.1 no signal
742 Rash Erythematous 51 1.1 1.1 no signal
743 Bone Disorder 20 1.1 1.1 no signal
744 Motor Dysfunction 11 1.1 1.1 no signal
745 Balance Disorder 94 1.1 1.1 no signal
746 Diverticulitis 30 1.1 1.1 no signal
747 Nerve Compression 10 1.1 1.1 no signal
748 Blood Thyroid Stimulating Hormone Increased 10 1.1 1.1 no signal
749 Product Use In Unapproved Indication 264 1.1 1.1 no signal
750 Productive Cough 51 1.1 1.1 no signal
751 Confusional State 174 1.1 1.1 no signal
752 Blood Cholesterol Increased 50 1.1 1.1 no signal
753 Rib Fracture 22 1.1 1.1 no signal
754 Covid-19 189 1.1 1.1 no signal
755 Respiratory Disorder 32 1.1 1.1 no signal
756 Cardiac Disorder 100 1.1 1.1 no signal
757 Folliculitis 11 1.1 1.1 no signal
758 Eye Inflammation 10 1.1 1.1 no signal
759 Alopecia 207 1.0 1.0 no signal
760 Urinary Retention 35 1.0 1.0 no signal
761 Cytokine Release Syndrome 20 1.0 1.0 no signal
762 Dysgeusia 78 1.0 1.0 no signal
763 Back Disorder 17 1.0 1.0 no signal
764 Ageusia 26 1.0 1.0 no signal
765 Syncope 104 1.0 1.0 no signal
766 Drug-induced Liver Injury 32 1.0 1.0 no signal
767 Hypoaesthesia 155 1.0 1.0 no signal
768 Arthritis 81 1.0 1.0 no signal
769 Hip Fracture 33 1.0 1.0 no signal
770 Drug Eruption 18 1.0 1.0 no signal
771 Blood Pressure Systolic Increased 20 1.0 1.0 no signal
772 Hyperhidrosis 131 1.0 1.0 no signal
773 Clostridium Difficile Infection 22 1.0 1.0 no signal
774 Tubulointerstitial Nephritis 19 1.0 1.0 no signal
775 Condition Aggravated 306 1.0 1.0 no signal
776 Dry Mouth 82 1.0 1.0 no signal
777 Colitis 38 1.0 1.0 no signal
778 Sciatica 16 1.0 1.0 no signal
779 Body Temperature Decreased 10 1.0 1.0 no signal
780 Swelling 94 1.0 1.0 no signal
781 Gastric Disorder 35 1.0 1.0 no signal
782 Sleep Disorder 70 1.0 1.0 no signal
783 Hypoaesthesia Oral 15 1.0 1.0 no signal
784 Blood Pressure Decreased 66 1.0 1.0 no signal
785 Aphasia 30 1.0 1.0 no signal
786 Heart Rate Increased 98 1.0 1.0 no signal
787 Eyelid Ptosis 10 1.0 1.0 no signal
788 Eye Infection 11 1.0 1.0 no signal
789 Neurotoxicity 17 1.0 1.0 no signal
790 Secretion Discharge 12 1.0 1.0 no signal
791 Hyperthyroidism 14 1.0 1.0 no signal
792 Inappropriate Schedule Of Product Administration 171 1.0 1.0 no signal
793 Intervertebral Disc Degeneration 9 1.0 1.0 no signal
794 Illness 97 1.0 1.0 no signal
795 Shock 22 1.0 1.0 no signal
796 Apathy 14 1.0 1.0 no signal
797 Dysphonia 56 1.0 1.0 no signal
798 Thirst 17 1.0 1.0 no signal
799 Gallbladder Disorder 17 0.9 0.9 no signal
800 Blister 53 0.9 0.9 no signal
801 Hot Flush 71 0.9 0.9 no signal
802 Ear Infection 25 0.9 0.9 no signal
803 Unresponsive To Stimuli 24 0.9 0.9 no signal
804 Gait Disturbance 179 0.9 0.9 no signal
805 Choking 18 0.9 0.9 no signal
806 Pain Of Skin 25 0.9 0.9 no signal
807 Heart Rate Irregular 21 0.9 0.9 no signal
808 End Stage Renal Disease 17 0.9 0.9 no signal
809 Swelling Face 60 0.9 0.9 no signal
810 Hip Arthroplasty 14 0.9 0.9 no signal
811 Chronic Obstructive Pulmonary Disease 48 0.9 0.9 no signal
812 Visual Impairment 113 0.9 0.9 no signal
813 Amnesia 60 0.9 0.9 no signal
814 Kidney Infection 18 0.9 0.9 no signal
815 Wrist Fracture 11 0.9 0.9 no signal
816 Pain In Jaw 26 0.9 0.9 no signal
817 Gastrointestinal Pain 10 0.9 0.9 no signal
818 Feeling Hot 56 0.9 0.9 no signal
819 Chest Discomfort 93 0.9 0.9 no signal
820 Adverse Event 84 0.9 0.9 no signal
821 Photophobia 17 0.9 0.9 no signal
822 Tooth Fracture 10 0.9 0.9 no signal
823 Dental Caries 10 0.9 0.9 no signal
824 Blood Triglycerides Increased 16 0.9 0.9 no signal
825 Asthma 101 0.9 0.9 no signal
826 Tendonitis 14 0.9 0.9 no signal
827 Insomnia 239 0.9 0.9 no signal
828 Tooth Disorder 20 0.9 0.9 no signal
829 Ileus 11 0.9 0.9 no signal
830 Depressed Mood 47 0.9 0.9 no signal
831 Product Taste Abnormal 12 0.9 0.9 no signal
832 Stress 64 0.9 0.9 no signal
833 Hair Texture Abnormal 12 0.9 0.9 no signal
834 Sinusitis 91 0.9 0.9 no signal
835 Acute Hepatic Failure 12 0.9 0.9 no signal
836 Tooth Abscess 9 0.9 0.9 no signal
837 Prescribed Overdose 17 0.9 0.9 no signal
838 Intentional Product Misuse 76 0.9 0.9 no signal
839 Blood Pressure Fluctuation 21 0.9 0.9 no signal
840 Nasopharyngitis 161 0.9 0.9 no signal
841 Drug Toxicity 12 0.9 0.9 no signal
842 Central Nervous System Lesion 12 0.9 0.9 no signal
843 Bradycardia 46 0.9 0.9 no signal
844 Foetal Exposure During Pregnancy 70 0.9 0.9 no signal
845 Appendicitis 8 0.9 0.9 no signal
846 Loss Of Consciousness 110 0.9 0.9 no signal
847 Disorientation 34 0.9 0.9 no signal
848 Generalised Tonic-clonic Seizure 14 0.9 0.9 no signal
849 Metastases To Liver 15 0.9 0.9 no signal
850 Joint Dislocation 9 0.9 0.9 no signal
851 Blood Creatine Phosphokinase Increased 25 0.9 0.9 no signal
852 Carpal Tunnel Syndrome 12 0.9 0.9 no signal
853 Thinking Abnormal 16 0.9 0.9 no signal
854 Depression 195 0.9 0.8 no signal
855 Rotator Cuff Syndrome 11 0.9 0.9 no signal
856 Skin Reaction 12 0.9 0.9 no signal
857 Osteopenia 13 0.8 0.8 no signal
858 Photosensitivity Reaction 14 0.8 0.8 no signal
859 Intentional Dose Omission 23 0.8 0.8 no signal
860 Delirium 29 0.8 0.8 no signal
861 Bronchospasm 12 0.8 0.8 no signal
862 Nasal Congestion 49 0.8 0.8 no signal
863 Road Traffic Accident 35 0.8 0.8 no signal
864 Tooth Infection 11 0.8 0.8 no signal
865 Swollen Tongue 26 0.8 0.8 no signal
866 Dry Skin 109 0.8 0.8 no signal
867 Osteoporosis 34 0.8 0.8 no signal
868 Product Use Issue 154 0.8 0.8 no signal
869 Muscle Twitching 19 0.8 0.8 no signal
870 Heart Rate Decreased 29 0.8 0.8 no signal
871 Drug Effective For Unapproved Indication 24 0.8 0.8 no signal
872 Inflammatory Bowel Disease 8 0.8 0.8 no signal
873 Palmar-plantar Erythrodysaesthesia Syndrome 19 0.8 0.8 no signal
874 Depressed Level Of Consciousness 32 0.8 0.8 no signal
875 Blood Glucose Abnormal 15 0.8 0.8 no signal
876 Diplopia 21 0.8 0.8 no signal
877 Spinal Fracture 16 0.8 0.8 no signal
878 Upper Limb Fracture 16 0.8 0.8 no signal
879 Joint Swelling 96 0.8 0.8 no signal
880 Skin Fissures 15 0.8 0.8 no signal
881 Vision Blurred 108 0.8 0.8 no signal
882 Product Prescribing Issue 16 0.8 0.8 no signal
883 Presyncope 19 0.8 0.8 no signal
884 Drug Level Increased 13 0.8 0.8 no signal
885 Initial Insomnia 8 0.8 0.8 no signal
886 Eye Swelling 29 0.8 0.8 no signal
887 Blood Pressure Increased 120 0.8 0.8 no signal
888 Mobility Decreased 56 0.8 0.8 no signal
889 Hernia 15 0.8 0.8 no signal
890 Coma 37 0.8 0.8 no signal
891 Rhinorrhoea 50 0.8 0.8 no signal
892 Ankle Fracture 12 0.8 0.8 no signal
893 Femur Fracture 24 0.8 0.8 no signal
894 Dry Eye 37 0.8 0.8 no signal
895 Hallucination, Visual 16 0.8 0.8 no signal
896 Osteonecrosis Of Jaw 19 0.8 0.8 no signal
897 Product Prescribing Error 18 0.8 0.8 no signal
898 Medication Error 42 0.8 0.8 no signal
899 Hypothyroidism 24 0.8 0.8 no signal
900 Osteoarthritis 32 0.8 0.8 no signal
901 Joint Range Of Motion Decreased 10 0.7 0.7 no signal
902 Lactic Acidosis 24 0.7 0.7 no signal
903 Skin Exfoliation 62 0.7 0.7 no signal
904 Nocturia 9 0.7 0.7 no signal
905 Paraesthesia 117 0.7 0.7 no signal
906 Type 2 Diabetes Mellitus 25 0.7 0.7 no signal
907 Body Height Decreased 8 0.7 0.7 no signal
908 Back Injury 8 0.7 0.7 no signal
909 Influenza Like Illness 61 0.7 0.7 no signal
910 Intervertebral Disc Protrusion 16 0.7 0.7 no signal
911 Abnormal Behaviour 29 0.7 0.7 no signal
912 Joint Stiffness 19 0.7 0.7 no signal
913 Hallucination 54 0.7 0.7 no signal
914 Respiratory Arrest 20 0.7 0.7 no signal
915 Diabetes Mellitus 55 0.7 0.7 no signal
916 Stevens-johnson Syndrome 16 0.7 0.7 no signal
917 Hypertensive Crisis 8 0.7 0.7 no signal
918 Throat Irritation 32 0.7 0.7 no signal
919 Glossodynia 16 0.7 0.7 no signal
920 Thyroid Disorder 11 0.7 0.7 no signal
921 Anxiety 203 0.7 0.7 no signal
922 Cognitive Disorder 33 0.7 0.7 no signal
923 Musculoskeletal Stiffness 62 0.7 0.7 no signal
924 Tremor 117 0.7 0.7 no signal
925 Bladder Disorder 7 0.7 0.7 no signal
926 Gastric Cancer 18 0.7 0.7 no signal
927 Arthropathy 39 0.7 0.7 no signal
928 Taste Disorder 14 0.7 0.7 no signal
929 Hypersensitivity 129 0.7 0.7 no signal
930 Paraesthesia Oral 10 0.7 0.7 no signal
931 Discomfort 42 0.7 0.7 no signal
932 Drug Ineffective 910 0.7 0.7 no signal
933 Anosmia 10 0.7 0.7 no signal
934 Epilepsy 21 0.7 0.7 no signal
935 Orthostatic Hypotension 12 0.7 0.7 no signal
936 Speech Disorder 36 0.7 0.7 no signal
937 Movement Disorder 22 0.7 0.7 no signal
938 Muscle Tightness 11 0.7 0.7 no signal
939 Sleep Apnoea Syndrome 13 0.7 0.7 no signal
940 Emotional Disorder 21 0.7 0.7 no signal
941 Scratch 7 0.7 0.7 no signal
942 Convulsion 39 0.7 0.7 no signal
943 Accident 8 0.7 0.7 no signal
944 Macular Degeneration 8 0.7 0.7 no signal
945 Adverse Drug Reaction 60 0.7 0.7 no signal
946 Nervous System Disorder 21 0.7 0.7 no signal
947 Disturbance In Attention 36 0.7 0.7 no signal
948 Myocardial Infarction 117 0.7 0.7 no signal
949 Agitation 49 0.7 0.7 no signal
950 Plasma Cell Myeloma 26 0.7 0.7 no signal
951 Cardiovascular Disorder 17 0.7 0.7 no signal
952 Migraine 63 0.7 0.7 no signal
953 Erectile Dysfunction 17 0.7 0.7 no signal
954 Pelvic Pain 12 0.7 0.7 no signal
955 Incorrect Dose Administered 147 0.7 0.6 no signal
956 Brain Neoplasm 6 0.7 0.7 no signal
957 Retinal Detachment 6 0.7 0.7 no signal
958 Product Physical Issue 13 0.7 0.7 no signal
959 Hypoacusis 28 0.6 0.6 no signal
960 Prescribed Underdose 13 0.6 0.6 no signal
961 Prostatic Specific Antigen Increased 9 0.6 0.6 no signal
962 Erythema 133 0.6 0.6 no signal
963 Drug Dispensing Error 10 0.6 0.6 no signal
964 Product Dispensing Error 14 0.6 0.6 no signal
965 Cyst 8 0.6 0.6 no signal
966 Erythema Multiforme 6 0.6 0.6 no signal
967 Hepatic Encephalopathy 6 0.6 0.6 no signal
968 Scar 11 0.6 0.6 no signal
969 Lower Respiratory Tract Infection 29 0.6 0.6 no signal
970 Hypoglycaemia 31 0.6 0.6 no signal
971 Drug Exposure During Pregnancy 22 0.6 0.6 no signal
972 Lacrimation Increased 19 0.6 0.6 no signal
973 Cyanosis 10 0.6 0.6 no signal
974 Poisoning 8 0.6 0.6 no signal
975 Eye Pain 35 0.6 0.6 no signal
976 Red Blood Cell Sedimentation Rate Increased 7 0.6 0.6 no signal
977 Respiratory Tract Congestion 10 0.6 0.6 no signal
978 Feeling Jittery 12 0.6 0.6 no signal
979 Lower Limb Fracture 12 0.6 0.6 no signal
980 Obstructive Airways Disorder 7 0.6 0.6 no signal
981 Glaucoma 12 0.6 0.6 no signal
982 Therapy Change 6 0.6 0.6 no signal
983 Surgery 36 0.6 0.6 no signal
984 Mental Impairment 15 0.6 0.6 no signal
985 Dermatitis Contact 7 0.6 0.6 no signal
986 Vitreous Floaters 6 0.6 0.6 no signal
987 Irritability 37 0.6 0.6 no signal
988 Inappropriate Schedule Of Drug Administration 44 0.6 0.6 no signal
989 Urticaria 101 0.6 0.6 no signal
990 Infusion Related Reaction 40 0.6 0.6 no signal
991 Sinus Disorder 12 0.6 0.6 no signal
992 Salivary Hypersecretion 6 0.6 0.6 no signal
993 Renal Injury 18 0.6 0.6 no signal
994 Conjunctivitis 11 0.6 0.6 no signal
995 Madarosis 7 0.6 0.6 no signal
996 Seizure 68 0.6 0.6 no signal
997 Pruritus Generalised 13 0.6 0.6 no signal
998 Uveitis 8 0.6 0.6 no signal
999 Dyskinesia 24 0.6 0.6 no signal
1000 Blindness 24 0.6 0.6 no signal
1001 Helicobacter Infection 6 0.6 0.6 no signal
1002 Eye Discharge 6 0.6 0.6 no signal
1003 Ear Discomfort 6 0.6 0.6 no signal
1004 Sneezing 13 0.6 0.6 no signal
1005 Nervousness 30 0.6 0.6 no signal
1006 Small Intestinal Obstruction 7 0.6 0.6 no signal
1007 Dermatitis Allergic 7 0.6 0.6 no signal
1008 Wrong Technique In Product Usage Process 112 0.6 0.6 no signal
1009 Drug Reaction With Eosinophilia And Systemic Symptoms 14 0.5 0.5 no signal
1010 Accidental Overdose 20 0.5 0.5 no signal
1011 Procedural Pain 15 0.5 0.5 no signal
1012 Acne 41 0.5 0.5 no signal
1013 Colitis Ulcerative 24 0.5 0.5 no signal
1014 Nerve Injury 6 0.5 0.5 no signal
1015 Visual Acuity Reduced 18 0.5 0.5 no signal
1016 Dysmenorrhoea 7 0.5 0.5 no signal
1017 Intestinal Perforation 6 0.5 0.5 no signal
1018 Grand Mal Convulsion 5 0.5 0.5 no signal
1019 Complication Associated With Device 7 0.5 0.5 no signal
1020 Musculoskeletal Disorder 10 0.5 0.5 no signal
1021 Autoimmune Disorder 5 0.5 0.5 no signal
1022 Economic Problem 8 0.5 0.5 no signal
1023 Eye Disorder 17 0.5 0.5 no signal
1024 Irritable Bowel Syndrome 11 0.5 0.5 no signal
1025 Cold Sweat 9 0.5 0.5 no signal
1026 Coronary Artery Occlusion 7 0.5 0.5 no signal
1027 Dysarthria 19 0.5 0.5 no signal
1028 Exposure During Pregnancy 31 0.5 0.5 no signal
1029 Brain Injury 5 0.5 0.5 no signal
1030 Withdrawal Syndrome 21 0.5 0.5 no signal
1031 Ovarian Cyst 5 0.5 0.5 no signal
1032 Eczema 25 0.5 0.5 no signal
1033 Sensory Disturbance 8 0.5 0.5 no signal
1034 Poor Venous Access 5 0.5 0.5 no signal
1035 Peritonitis 10 0.5 0.5 no signal
1036 Tooth Loss 10 0.5 0.5 no signal
1037 Mood Altered 13 0.5 0.5 no signal
1038 Mood Swings 15 0.5 0.5 no signal
1039 Infusion Site Pain 6 0.5 0.5 no signal
1040 Abnormal Dreams 13 0.5 0.5 no signal
1041 Breast Cancer Metastatic 5 0.5 0.5 no signal
1042 Restlessness 17 0.5 0.5 no signal
1043 Device Failure 7 0.5 0.5 no signal
1044 Rheumatoid Arthritis 52 0.5 0.5 no signal
1045 Mental Disorder 20 0.5 0.5 no signal
1046 Skin Irritation 21 0.5 0.5 no signal
1047 Systemic Lupus Erythematosus 16 0.5 0.5 no signal
1048 Local Swelling 8 0.5 0.5 no signal
1049 Expired Product Administered 15 0.5 0.5 no signal
1050 Ocular Hyperaemia 21 0.4 0.4 no signal
1051 Pancreatic Carcinoma 13 0.4 0.4 no signal
1052 Fistula 5 0.4 0.4 no signal
1053 Anger 15 0.4 0.4 no signal
1054 Rebound Effect 5 0.4 0.4 no signal
1055 Impaired Driving Ability 5 0.4 0.4 no signal
1056 Abscess 7 0.4 0.4 no signal
1057 Wrong Technique In Drug Usage Process 16 0.4 0.4 no signal
1058 Aphonia 6 0.4 0.4 no signal
1059 Unevaluable Event 32 0.4 0.4 no signal
1060 Pharyngeal Swelling 4 0.4 0.4 no signal
1061 Drug Administration Error 13 0.4 0.4 no signal
1062 Toxicity To Various Agents 69 0.4 0.4 no signal
1063 Underdose 30 0.4 0.4 no signal
1064 Respiratory Depression 5 0.4 0.4 no signal
1065 Disability 8 0.4 0.4 no signal
1066 Injection Site Discolouration 5 0.4 0.4 no signal
1067 Drug Withdrawal Syndrome Neonatal 6 0.4 0.4 no signal
1068 Contraindicated Product Administered 12 0.4 0.4 no signal
1069 Peritonitis Bacterial 4 0.4 0.4 no signal
1070 Glycosylated Haemoglobin Increased 10 0.4 0.4 no signal
1071 Eye Irritation 22 0.4 0.4 no signal
1072 Incorrect Product Administration Duration 8 0.4 0.4 no signal
1073 Flushing 40 0.4 0.4 no signal
1074 Blood Glucose Increased 74 0.4 0.4 no signal
1075 Drug Level Decreased 4 0.4 0.4 no signal
1076 Metastases To Central Nervous System 5 0.4 0.4 no signal
1077 Euphoric Mood 4 0.4 0.4 no signal
1078 Incorrect Drug Administration Duration 11 0.4 0.4 no signal
1079 Angioedema 17 0.4 0.4 no signal
1080 Pharyngeal Oedema 6 0.4 0.4 no signal
1081 Crying 14 0.4 0.4 no signal
1082 Unintended Pregnancy 4 0.4 0.4 no signal
1083 Breast Pain 4 0.4 0.4 no signal
1084 Hunger 5 0.4 0.4 no signal
1085 Fear 10 0.4 0.4 no signal
1086 Product Packaging Quantity Issue 4 0.4 0.4 no signal
1087 Blood Glucose Fluctuation 4 0.4 0.4 no signal
1088 Lip Swelling 12 0.4 0.4 no signal
1089 Psychomotor Hyperactivity 6 0.4 0.4 no signal
1090 Amenorrhoea 6 0.4 0.4 no signal
1091 Drug Prescribing Error 7 0.4 0.4 no signal
1092 Aggression 18 0.4 0.4 no signal
1093 Drug Effect Less Than Expected 5 0.4 0.4 no signal
1094 Activities Of Daily Living Impaired 7 0.3 0.3 no signal
1095 Nightmare 12 0.3 0.3 no signal
1096 Injury 24 0.3 0.3 no signal
1097 Therapeutic Product Effect Decreased 15 0.3 0.3 no signal
1098 Spinal Operation 4 0.3 0.3 no signal
1099 Vaginal Haemorrhage 14 0.3 0.3 no signal
1100 Extra Dose Administered 13 0.3 0.3 no signal
1101 Drug Hypersensitivity 63 0.3 0.3 no signal
1102 Product Packaging Issue 3 0.3 0.3 no signal
1103 Prostate Cancer 26 0.3 0.3 no signal
1104 Deformity 3 0.3 0.3 no signal
1105 Breast Cancer 30 0.3 0.3 no signal
1106 Hair Colour Changes 4 0.3 0.3 no signal
1107 Injection Site Irritation 4 0.3 0.3 no signal
1108 Product Substitution Issue 18 0.3 0.3 no signal
1109 Blood Glucose Decreased 15 0.3 0.3 no signal
1110 Affect Lability 3 0.3 0.3 no signal
1111 Parkinsonism 3 0.3 0.3 no signal
1112 Metastases To Bone 5 0.3 0.3 no signal
1113 Inability To Afford Medication 3 0.3 0.3 no signal
1114 Emotional Distress 36 0.3 0.3 no signal
1115 Menstruation Delayed 3 0.3 0.3 no signal
1116 Suicidal Ideation 26 0.3 0.3 no signal
1117 Diabetes Mellitus Inadequate Control 5 0.3 0.3 no signal
1118 Eye Pruritus 9 0.3 0.3 no signal
1119 Injection Site Haematoma 4 0.3 0.3 no signal
1120 Overdose 57 0.3 0.3 no signal
1121 Serotonin Syndrome 5 0.3 0.3 no signal
1122 Hepatitis C 3 0.2 0.2 no signal
1123 Libido Decreased 3 0.2 0.2 no signal
1124 Skin Burning Sensation 17 0.2 0.2 no signal
1125 Anaphylactic Reaction 13 0.2 0.2 no signal
1126 Intraocular Pressure Increased 3 0.2 0.2 no signal
1127 Metrorrhagia 4 0.2 0.2 no signal
1128 Pharmaceutical Product Complaint 6 0.2 0.2 no signal
1129 Incorrect Product Storage 3 0.2 0.2 no signal
1130 Synovitis 4 0.2 0.2 no signal
1131 Therapeutic Response Shortened 7 0.2 0.2 no signal
1132 No Adverse Event 39 0.2 0.2 no signal
1133 Bladder Cancer 13 0.2 0.2 no signal
1134 Application Site Rash 3 0.2 0.2 no signal
1135 Circumstance Or Information Capable Of Leading To Medication Error 7 0.2 0.2 no signal
1136 Product Storage Error 18 0.2 0.2 no signal
1137 Meningioma 3 0.2 0.2 no signal
1138 Product Quality Issue 27 0.2 0.2 no signal
1139 Intentional Self-injury 4 0.2 0.2 no signal
1140 Injection Site Warmth 4 0.2 0.2 no signal
1141 Incorrect Route Of Drug Administration 7 0.2 0.2 no signal
1142 Gynaecomastia 6 0.2 0.2 no signal
1143 Injection Site Bruising 15 0.2 0.2 no signal
1144 Drug Effect Incomplete 7 0.2 0.2 no signal
1145 Bone Density Decreased 6 0.2 0.2 no signal
1146 Menstruation Irregular 5 0.2 0.2 no signal
1147 Needle Issue 5 0.2 0.2 no signal
1148 Injection Site Erythema 21 0.2 0.2 no signal
1149 Injection Site Rash 5 0.2 0.2 no signal
1150 Drug Effect Decreased 9 0.2 0.2 no signal
1151 Product Complaint 4 0.2 0.2 no signal
1152 Application Site Erythema 4 0.2 0.2 no signal
1153 Device Issue 13 0.1 0.1 no signal
1154 Multiple Sclerosis 7 0.1 0.1 no signal
1155 Renal Cancer 7 0.1 0.1 no signal
1156 Product Preparation Error 3 0.1 0.1 no signal
1157 Psoriasis 17 0.1 0.1 no signal
1158 Injection Site Pain 39 0.1 0.1 no signal
1159 Device Breakage 5 0.1 0.1 no signal
1160 Injection Site Urticaria 3 0.1 0.1 no signal
1161 Hepatic Cancer 3 0.1 0.1 no signal
1162 Injection Site Pruritus 8 0.1 0.1 no signal
1163 Completed Suicide 10 0.1 0.1 no signal
1164 Drug Withdrawal Syndrome 10 0.1 0.1 no signal
1165 Wrong Technique In Device Usage Process 5 0.1 0.1 no signal
1166 Dermatitis Atopic 5 0.1 0.1 no signal
1167 Oesophageal Carcinoma 3 0.1 0.1 no signal
1168 Drug Dependence 15 0.1 0.1 no signal
1169 Device Dislocation 4 0.1 0.1 no signal
1170 Injection Site Haemorrhage 7 0.1 0.1 no signal
1171 Drug Abuse 7 0.1 0.1 no signal
1172 Device Difficult To Use 3 0.0 0.0 no signal