OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Levomilnacipran Hydrochloride

130 flagged reaction(s) · 4,546 total co-reports · max PRR 91.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Taste Disorder 165 91.4 99.9 signal
2 Epilepsy 164 59.5 65.0 signal
3 Wound Infection 34 34.5 35.1 signal
4 Hypercholesterolaemia 27 31.1 31.6 signal
5 Folliculitis 29 31.0 31.4 signal
6 Back Injury 27 27.5 27.9 signal
7 Synovitis 44 26.9 27.5 signal
8 Pericarditis 39 25.8 26.3 signal
9 Pemphigus 29 25.7 26.1 signal
10 Gastrooesophageal Reflux Disease 181 24.9 27.4 signal
11 Red Blood Cell Sedimentation Rate Increased 24 23.9 24.2 signal
12 Bursitis 24 21.9 22.2 signal
13 Migraine 179 20.8 22.9 signal
14 Helicobacter Infection 19 20.5 20.7 signal
15 Laryngitis 20 20.3 20.5 signal
16 Drug Intolerance 173 19.8 21.7 signal
17 Joint Range Of Motion Decreased 24 19.8 20.0 signal
18 Prescribed Overdose 30 17.1 17.3 signal
19 Irritable Bowel Syndrome 32 16.5 16.8 signal
20 Autoimmune Disorder 14 16.1 16.2 signal
21 Memory Impairment 200 16.0 17.8 signal
22 Hand Deformity 19 16.0 16.2 signal
23 Wound 40 15.9 16.2 signal
24 Contraindicated Product Administered 41 15.0 15.3 signal
25 Fibromyalgia 33 15.0 15.2 signal
26 Hypoaesthesia 191 14.0 15.5 signal
27 Maternal Exposure During Pregnancy 110 13.7 14.5 signal
28 Sleep Disorder Due To A General Medical Condition 20 13.6 13.8 signal
29 Paraesthesia 189 13.2 14.6 signal
30 Glossodynia 26 12.8 13.0 signal
31 Prescribed Underdose 23 12.7 12.8 signal
32 Hepatic Cirrhosis 21 12.4 12.5 signal
33 Serotonin Syndrome 21 12.1 12.2 signal
34 Gait Inability 34 11.3 11.5 signal
35 Lower Limb Fracture 18 10.4 10.5 signal
36 Obesity 15 10.4 10.4 signal
37 C-reactive Protein Increased 34 10.3 10.5 signal
38 Night Sweats 30 10.3 10.4 signal
39 Ear Pain 18 10.2 10.3 signal
40 Abdominal Pain Upper 189 10.1 11.1 signal
41 Osteoarthritis 39 10.1 10.3 signal
42 Joint Stiffness 24 10.1 10.2 signal
43 Pulmonary Fibrosis 17 9.8 9.9 signal
44 Type 2 Diabetes Mellitus 30 9.8 9.9 signal
45 Systemic Lupus Erythematosus 31 9.7 9.8 signal
46 Therapeutic Product Effect Decreased 38 9.4 9.6 signal
47 Hip Arthroplasty 13 9.4 9.5 signal
48 Joint Dislocation 9 9.4 9.5 signal
49 Urinary Retention 28 9.3 9.4 signal
50 Impaired Healing 27 9.1 9.2 signal
51 Respiratory Disorder 24 8.8 8.9 signal
52 Sleep Disorder 55 8.7 8.9 signal
53 Stomatitis 47 8.5 8.7 signal
54 Suicidal Ideation 71 8.5 8.8 signal
55 Sciatica 12 8.3 8.4 signal
56 Blood Cholesterol Increased 35 8.3 8.4 signal
57 Psoriatic Arthropathy 30 8.2 8.3 signal
58 Foot Deformity 8 7.9 8.0 signal
59 Coeliac Disease 7 7.9 7.9 signal
60 Crying 25 7.5 7.6 signal
61 Sleep Apnoea Syndrome 13 7.5 7.5 signal
62 Inflammation 34 7.3 7.4 signal
63 Neuralgia 16 7.3 7.3 signal
64 Incorrect Route Of Product Administration 11 7.2 7.2 signal
65 Hyperhidrosis 83 7.1 7.4 signal
66 Delirium 22 7.0 7.1 signal
67 Pregnancy 12 6.5 6.6 signal
68 Wheezing 35 6.5 6.6 signal
69 Arthropathy 33 6.5 6.6 signal
70 Thinking Abnormal 11 6.5 6.5 signal
71 Dry Mouth 47 6.4 6.5 signal
72 Liver Injury 14 6.4 6.4 signal
73 Knee Arthroplasty 12 6.3 6.4 signal
74 Carpal Tunnel Syndrome 8 6.3 6.3 signal
75 Depression 130 6.3 6.7 signal
76 Anger 19 6.2 6.2 signal
77 Apathy 8 6.1 6.1 signal
78 Irritability 33 6.0 6.1 signal
79 Withdrawal Syndrome 23 6.0 6.1 signal
80 Nerve Injury 6 5.9 5.9 signal
81 Neck Pain 30 5.9 6.0 signal
82 Swelling 50 5.9 6.0 signal
83 Therapeutic Product Effect Incomplete 37 5.8 5.9 signal
84 Disability 10 5.6 5.6 signal
85 Blister 28 5.5 5.6 signal
86 Infusion Related Reaction 33 5.5 5.6 signal
87 Heart Rate Increased 49 5.4 5.6 signal
88 Treatment Failure 38 5.1 5.2 signal
89 Rheumatoid Arthritis 52 5.1 5.2 signal
90 Bipolar Disorder 5 5.0 5.0 signal
91 Product Use In Unapproved Indication 111 5.0 5.3 signal
92 Cholecystectomy 5 4.8 4.9 signal
93 Panic Attack 16 4.8 4.9 signal
94 Appendicitis 4 4.7 4.7 signal
95 Road Traffic Accident 18 4.7 4.8 signal
96 Discomfort 26 4.7 4.8 signal
97 Back Disorder 7 4.7 4.7 signal
98 Mania 7 4.7 4.7 signal
99 Increased Appetite 8 4.7 4.7 signal
100 Affect Lability 4 4.6 4.6 signal
101 Injury 29 4.5 4.6 signal
102 Frequent Bowel Movements 11 4.5 4.5 signal
103 Agitation 30 4.5 4.5 signal
104 Brain Injury 4 4.4 4.4 signal
105 Euphoric Mood 4 4.3 4.3 signal
106 Hunger 5 4.1 4.1 signal
107 Paranoia 6 3.8 3.8 signal
108 Sedation 9 3.8 3.8 signal
109 Sexual Dysfunction 4 3.8 3.8 signal
110 Therapeutic Response Unexpected 15 3.7 3.7 signal
111 Spinal Operation 4 3.6 3.6 signal
112 Ill-defined Disorder 20 3.6 3.6 signal
113 Nightmare 11 3.5 3.5 signal
114 Akathisia 4 3.2 3.2 signal
115 Expired Product Administered 9 3.0 3.0 signal
116 Product Quality Issue 36 2.9 3.0 signal
117 Suicide Attempt 16 2.9 2.9 signal
118 Product Physical Issue 5 2.8 2.8 no signal
119 Mood Swings 8 2.8 2.8 signal
120 Libido Decreased 3 2.7 2.7 no signal
121 Muscle Spasticity 3 2.7 2.7 no signal
122 Tardive Dyskinesia 5 1.9 1.9 no signal
123 Foetal Exposure During Pregnancy 14 1.9 1.9 no signal
124 Drug Withdrawal Syndrome 15 1.9 1.9 no signal
125 Injection Site Urticaria 4 1.8 1.8 no signal
126 Psoriasis 21 1.8 1.8 no signal
127 Injection Site Warmth 3 1.6 1.6 no signal
128 Multiple Sclerosis Relapse 9 1.4 1.4 no signal
129 Intentional Overdose 8 1.4 1.4 no signal
130 Product Adhesion Issue 3 0.9 0.9 no signal