Drug

Lomustine

76 flagged reaction(s) · 2,068 total co-reports · max PRR 24.2

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Haematotoxicity	27	24.2	24.4	signal
2	Acute Myeloid Leukaemia	38	20.2	20.5	signal
3	Blood Count Abnormal	37	20.0	20.2	signal
4	Myelodysplastic Syndrome	30	17.2	17.4	signal
5	Thrombocytopenia	180	13.4	14.3	signal
6	Bone Marrow Failure	32	13.0	13.1	signal
7	Hospice Care	15	12.6	12.7	signal
8	Mucosal Inflammation	39	12.4	12.6	signal
9	Hemiparesis	24	11.7	11.8	signal
10	Lymphopenia	19	11.2	11.3	signal
11	Neurotoxicity	23	11.0	11.1	signal
12	Neoplasm Progression	46	10.9	11.0	signal
13	Rebound Effect	14	10.2	10.3	signal
14	Disease Progression	141	9.9	10.4	signal
15	Platelet Count Decreased	112	8.7	9.1	signal
16	Neutropenia	130	7.9	8.3	signal
17	Ataxia	11	7.6	7.7	signal
18	Hepatic Cytolysis	11	7.5	7.5	signal
19	Neutrophil Count Increased	9	7.3	7.3	signal
20	Incontinence	9	7.0	7.1	signal
21	Posterior Reversible Encephalopathy Syndrome	8	7.0	7.0	signal
22	Therapy Change	8	6.9	6.9	signal
23	Febrile Neutropenia	54	6.8	6.9	signal
24	Hepatotoxicity	18	6.7	6.8	signal
25	Body Temperature Decreased	8	6.7	6.7	signal
26	Lymphocyte Count Decreased	14	6.6	6.6	signal
27	Seizure	88	6.4	6.5	signal
28	Polyneuropathy	9	6.3	6.3	signal
29	Type 2 Diabetes Mellitus	25	6.1	6.2	signal
30	Pulmonary Thrombosis	8	6.1	6.1	signal
31	Blood Pressure Systolic Increased	14	5.9	5.9	signal
32	Mitral Valve Incompetence	8	5.9	5.9	signal
33	Malignant Neoplasm Progression	71	5.8	5.9	signal
34	Toxic Skin Eruption	7	5.7	5.8	signal
35	Proteinuria	13	5.7	5.7	signal
36	Inappropriate Antidiuretic Hormone Secretion	7	5.7	5.7	signal
37	Brain Neoplasm	6	5.4	5.4	signal
38	Leukopenia	32	5.3	5.4	signal
39	Brain Oedema	8	5.2	5.3	signal
40	Red Blood Cell Count Decreased	18	5.2	5.2	signal
41	Pancytopenia	34	5.1	5.1	signal
42	Cardiomyopathy	9	5.0	5.1	signal
43	Toxic Epidermal Necrolysis	9	4.9	5.0	signal
44	Full Blood Count Decreased	12	4.9	4.9	signal
45	Cytopenia	7	4.9	4.9	signal
46	Osteonecrosis	19	4.7	4.8	signal
47	Neoplasm	6	4.3	4.3	signal
48	White Blood Cell Count Decreased	56	4.3	4.3	signal
49	Multiple Organ Dysfunction Syndrome	14	4.2	4.2	signal
50	Coordination Abnormal	7	4.1	4.1	signal
51	Liver Injury	12	4.1	4.1	signal
52	Cognitive Disorder	23	4.1	4.1	signal
53	Motor Dysfunction	5	4.1	4.1	signal
54	Hyperbilirubinaemia	5	4.0	4.0	signal
55	Full Blood Count Abnormal	5	3.9	3.9	signal
56	Myelosuppression	16	3.9	3.9	signal
57	Neutrophil Count Decreased	19	3.9	3.9	signal
58	Heart Rate Decreased	16	3.8	3.8	signal
59	Oral Discomfort	6	3.6	3.6	signal
60	Drug Resistance	11	3.5	3.6	signal
61	Hepatocellular Injury	6	3.5	3.5	signal
62	Cholestasis	8	3.5	3.5	signal
63	Speech Disorder	21	3.3	3.3	signal
64	Therapy Partial Responder	6	3.3	3.3	signal
65	Therapy Cessation	20	3.2	3.3	signal
66	Deafness	10	3.2	3.2	signal
67	Convulsion	21	3.0	3.0	signal
68	Metastases To Lung	4	2.9	2.9	no signal
69	Disease Recurrence	16	2.8	2.8	signal
70	Haemorrhage Intracranial	5	2.8	2.8	no signal
71	Drug Dispensing Error	5	2.7	2.7	no signal
72	Death	262	2.5	2.7	signal
73	Pneumocystis Jirovecii Pneumonia	3	2.5	2.5	no signal
74	Palmar-plantar Erythrodysaesthesia Syndrome	5	1.8	1.8	no signal
75	Drug Effect Incomplete	7	1.6	1.6	no signal
76	Plasma Cell Myeloma	7	1.5	1.5	no signal