OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Medroxyprogesterone Acetate

1,181 flagged reaction(s) · 106,977 total co-reports · max PRR 8,752.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Olfactory Groove Meningioma 21 8,752.0 8,755.8 signal
2 Meningioma 11,275 1,443.2 1,868.2 signal
3 Pregnancy With Injectable Contraceptive 158 1,175.9 1,179.6 signal
4 Progesterone Receptor Assay Positive 673 1,078.8 1,093.6 signal
5 Oestrogen Receptor Assay Positive 773 897.4 911.6 signal
6 Meningioma Benign 590 856.8 867.1 signal
7 Intracranial Meningioma Malignant 53 613.6 614.2 signal
8 Contralateral Breast Cancer 102 408.7 409.6 signal
9 Breast Cancer In Situ 517 285.8 288.8 signal
10 Breast Cancer Female 9,771 242.8 302.2 signal
11 Malignant Breast Lump Removal 49 240.3 240.5 signal
12 Biopsy Breast Abnormal 29 185.9 186.0 signal
13 Breast Microcalcification 26 115.3 115.3 signal
14 Breast Operation 105 62.7 62.8 signal
15 Breast Cancer Metastatic 1,383 62.6 64.4 signal
16 Breast Lump Removal 28 57.5 57.5 signal
17 Persistent Genital Arousal Disorder 23 46.3 46.3 signal
18 Fibrocystic Breast Disease 67 41.7 41.8 signal
19 Breast Cancer 8,169 40.2 48.0 signal
20 Ovarian Cancer Metastatic 71 39.0 39.0 signal
21 Breast Reconstruction 30 36.6 36.6 signal
22 Breast Hyperplasia 27 34.9 35.0 signal
23 Mammogram Abnormal 47 31.7 31.7 signal
24 Anovulatory Cycle 14 30.9 30.9 signal
25 Mastectomy 116 30.1 30.2 signal
26 Endometrial Hypertrophy 26 29.1 29.1 signal
27 Biopsy Breast 20 28.6 28.7 signal
28 Unintended Pregnancy 648 27.9 28.3 signal
29 Infertility Female 89 26.3 26.3 signal
30 Ovarian Cancer 499 24.1 24.3 signal
31 Clear Cell Renal Cell Carcinoma 36 23.4 23.5 signal
32 Endometrial Disorder 21 23.1 23.1 signal
33 Breast Calcifications 40 22.2 22.2 signal
34 Fallopian Tube Disorder 14 20.8 20.8 signal
35 Infertility 70 20.7 20.7 signal
36 Endometrial Hyperplasia 32 17.3 17.3 signal
37 Pregnancy Test Positive 15 16.9 16.9 signal
38 Breast Cancer Recurrent 120 16.7 16.8 signal
39 Lymphadenectomy 36 16.1 16.1 signal
40 Endometrial Cancer 81 16.1 16.1 signal
41 Cervicitis 16 15.6 15.6 signal
42 Injection Site Abscess 84 14.8 14.8 signal
43 Complications Of Maternal Exposure To Therapeutic Drugs 23 14.6 14.6 signal
44 Amenorrhoea 556 14.6 14.7 signal
45 Blood Oestrogen Decreased 22 14.1 14.1 signal
46 Suppressed Lactation 23 13.2 13.2 signal
47 Invasive Lobular Breast Carcinoma 14 11.9 11.9 signal
48 Breast Cyst 47 11.4 11.5 signal
49 Premenstrual Syndrome 36 11.4 11.5 signal
50 Uterine Dilation And Curettage 23 11.0 11.0 signal
51 Metrorrhagia 430 10.8 10.9 signal
52 Polycystic Ovaries 39 10.7 10.8 signal
53 Invasive Ductal Breast Carcinoma 67 10.7 10.7 signal
54 Menometrorrhagia 45 10.6 10.6 signal
55 Menorrhagia 485 10.5 10.6 signal
56 Uterine Haemorrhage 103 10.5 10.5 signal
57 Smear Cervix Abnormal 34 10.3 10.3 signal
58 Premature Menopause 22 10.3 10.3 signal
59 Adenomyosis 14 10.3 10.3 signal
60 Benign Breast Neoplasm 24 10.1 10.1 signal
61 Uterine Polyp 42 10.1 10.1 signal
62 Atrophic Vulvovaginitis 17 10.1 10.1 signal
63 Radiotherapy 41 9.2 9.2 signal
64 Osteopenia 309 8.7 8.8 signal
65 Postmenopausal Haemorrhage 49 8.2 8.2 signal
66 Uterine Disorder 44 8.1 8.1 signal
67 Dysfunctional Uterine Bleeding 23 8.0 8.1 signal
68 Gallbladder Cancer 27 7.9 7.9 signal
69 Injection Site Atrophy 30 7.8 7.8 signal
70 Drug Exposure Before Pregnancy 18 7.6 7.6 signal
71 Hormone Level Abnormal 84 7.5 7.5 signal
72 Renal Mass 36 7.5 7.5 signal
73 Breast Mass 114 7.3 7.3 signal
74 Breast Disorder 34 7.1 7.1 signal
75 Cervical Dysplasia 36 7.1 7.1 signal
76 Uterine Leiomyoma 118 6.9 6.9 signal
77 Abortion Missed 20 6.7 6.7 signal
78 Disturbance In Sexual Arousal 14 6.5 6.5 signal
79 Vulvovaginal Dryness 47 6.3 6.3 signal
80 Osteoporotic Fracture 28 6.2 6.2 signal
81 Vaginal Odour 18 6.1 6.1 signal
82 Breast Discharge 25 6.1 6.1 signal
83 Hirsutism 19 6.1 6.1 signal
84 Dyspareunia 65 6.1 6.1 signal
85 Breast Neoplasm 14 5.8 5.8 signal
86 Pelvic Inflammatory Disease 20 5.7 5.7 signal
87 Radiation Skin Injury 15 5.5 5.5 signal
88 Menstrual Disorder 101 5.3 5.3 signal
89 Breast Tenderness 92 5.2 5.2 signal
90 Skin Striae 18 5.2 5.2 signal
91 Blood Urea Decreased 15 5.1 5.1 signal
92 Oligomenorrhoea 26 5.1 5.1 signal
93 Colonic Polyp 20 5.1 5.1 signal
94 Metastases To Lymph Nodes 80 5.1 5.1 signal
95 Osteoporosis 490 5.1 5.1 signal
96 Ovarian Cyst 119 5.1 5.1 signal
97 Uterine Perforation 101 5.0 5.1 signal
98 Seborrhoeic Keratosis 17 5.0 5.0 signal
99 Menopausal Symptoms 26 4.9 4.9 signal
100 Menopause 29 4.9 4.9 signal
101 Endometriosis 54 4.8 4.8 signal
102 Dysmenorrhoea 147 4.8 4.8 signal
103 Device Occlusion 155 4.8 4.8 signal
104 Ectopic Pregnancy 34 4.7 4.7 signal
105 Joint Instability 15 4.7 4.7 signal
106 Incorrect Dose Administered By Device 277 4.7 4.7 signal
107 Syringe Issue 190 4.6 4.6 signal
108 Lymphoedema 72 4.5 4.5 signal
109 Benign Intracranial Hypertension 13 4.4 4.4 signal
110 Illusion 17 4.3 4.3 signal
111 Fine Motor Skill Dysfunction 29 4.3 4.3 signal
112 Device Connection Issue 20 4.2 4.2 signal
113 Mitral Valve Prolapse 16 4.1 4.1 signal
114 Vaginal Haemorrhage 405 4.1 4.1 signal
115 Complex Regional Pain Syndrome 14 4.0 4.0 signal
116 Heavy Menstrual Bleeding 74 4.0 4.0 signal
117 Uterine Spasm 17 3.9 3.9 signal
118 Breast Swelling 25 3.9 3.9 signal
119 Haemorrhage In Pregnancy 13 3.9 3.9 signal
120 Mastitis 17 3.8 3.8 signal
121 Breast Pain 95 3.8 3.8 signal
122 Serum Ferritin Decreased 15 3.7 3.7 signal
123 Spinal Osteoarthritis 77 3.7 3.7 signal
124 Pelvic Pain 158 3.7 3.7 signal
125 Coital Bleeding 13 3.6 3.6 signal
126 Needle Issue 243 3.6 3.6 signal
127 Loss Of Libido 75 3.6 3.6 signal
128 Liquid Product Physical Issue 58 3.5 3.5 signal
129 Cholecystitis Chronic 55 3.5 3.5 signal
130 Pre-existing Condition Improved 51 3.4 3.4 signal
131 Breast Enlargement 26 3.4 3.4 signal
132 Medical Device Pain 17 3.3 3.4 signal
133 Injection Site Inflammation 38 3.3 3.3 signal
134 Livedo Reticularis 16 3.3 3.3 signal
135 Injection Site Infection 25 3.3 3.3 signal
136 Tunnel Vision 14 3.2 3.2 signal
137 White Blood Cells Urine Positive 14 3.2 3.2 signal
138 Product Administration Error 148 3.2 3.2 signal
139 Scoliosis 46 3.2 3.2 signal
140 Menstruation Irregular 196 3.1 3.2 signal
141 Intermenstrual Bleeding 38 3.1 3.1 signal
142 Device Leakage 310 3.1 3.1 signal
143 Lactose Intolerance 18 3.0 3.0 signal
144 Coma Scale Abnormal 20 3.0 3.0 signal
145 Medical Device Discomfort 21 2.9 2.9 signal
146 Hysterectomy 59 2.9 2.9 signal
147 Lumbar Spinal Stenosis 20 2.9 2.9 signal
148 Thrombophlebitis Superficial 21 2.9 2.9 signal
149 Polymenorrhoea 22 2.9 2.9 signal
150 Gallbladder Injury 13 2.8 2.8 signal
151 Stress Fracture 36 2.8 2.8 signal
152 Deformity 61 2.8 2.8 signal
153 Abortion 19 2.8 2.8 signal
154 Drug Exposure During Pregnancy 222 2.7 2.7 signal
155 Deep Vein Thrombosis 418 2.7 2.7 signal
156 Breast Cancer Stage Iii 41 2.7 2.7 signal
157 Vaginal Infection 30 2.7 2.7 signal
158 Device Mechanical Issue 82 2.7 2.7 signal
159 Scar 109 2.7 2.7 signal
160 Breast Cancer Stage Ii 53 2.7 2.7 signal
161 Mood Swings 200 2.7 2.7 signal
162 Temporomandibular Joint Syndrome 17 2.7 2.7 signal
163 Blood Pressure Diastolic Abnormal 16 2.6 2.6 signal
164 Libido Decreased 77 2.6 2.6 signal
165 Brain Neoplasm 57 2.6 2.6 signal
166 Abortion Spontaneous 248 2.6 2.6 signal
167 Product Use Complaint 95 2.6 2.6 signal
168 Cervix Carcinoma 24 2.6 2.6 signal
169 Vaginal Discharge 61 2.6 2.6 signal
170 Abnormal Uterine Bleeding 15 2.6 2.6 signal
171 Blood Pressure Diastolic Decreased 44 2.5 2.5 signal
172 Poor Quality Device Used 52 2.5 2.5 signal
173 Cerebrovascular Disorder 18 2.5 2.5 signal
174 Goitre 24 2.5 2.5 signal
175 Blood Pressure Diastolic Increased 27 2.5 2.5 signal
176 Rhinitis Allergic 25 2.4 2.4 signal
177 Intervertebral Disc Degeneration 52 2.4 2.4 signal
178 Muscle Fatigue 23 2.3 2.3 signal
179 Diverticulum 39 2.3 2.3 signal
180 Embolism Venous 16 2.2 2.2 signal
181 Cartilage Injury 13 2.2 2.2 signal
182 Varicose Vein 27 2.2 2.2 signal
183 Uterine Cancer 42 2.2 2.2 signal
184 Pulmonary Embolism 484 2.2 2.2 signal
185 Genital Haemorrhage 65 2.1 2.1 signal
186 Depression Suicidal 17 2.1 2.1 signal
187 Difficulty In Walking 17 2.1 2.1 signal
188 Maternal Exposure Timing Unspecified 18 2.1 2.1 signal
189 Peptic Ulcer 16 2.0 2.0 signal
190 Red Cell Distribution Width Increased 20 2.0 2.0 signal
191 Gallbladder Disorder 86 2.0 2.0 signal
192 Galactorrhoea 31 2.0 2.0 signal
193 Appendicectomy 17 2.0 2.0 signal
194 Vitamin B12 Deficiency 19 2.0 2.0 signal
195 Device Defective 76 2.0 2.0 no signal
196 Acne Cystic 14 2.0 2.0 no signal
197 Bipolar Disorder 50 1.9 1.9 no signal
198 Otitis Media 15 1.9 1.9 no signal
199 High Density Lipoprotein Decreased 15 1.9 1.9 no signal
200 Hair Growth Abnormal 31 1.9 1.9 no signal
201 Anxiety Disorder 15 1.9 1.9 no signal
202 Low Turnover Osteopathy 18 1.9 1.9 no signal
203 Decreased Interest 26 1.9 1.9 no signal
204 Monocyte Count Increased 16 1.9 1.9 no signal
205 Scleroderma 16 1.9 1.9 no signal
206 Bone Density Decreased 139 1.9 1.9 no signal
207 Major Depression 32 1.9 1.9 no signal
208 Onychomycosis 19 1.8 1.8 no signal
209 Bone Marrow Disorder 13 1.8 1.8 no signal
210 Injury 301 1.8 1.8 no signal
211 Glucose Tolerance Impaired 25 1.8 1.8 no signal
212 Pregnancy 86 1.8 1.8 no signal
213 Foot Fracture 78 1.7 1.7 no signal
214 Skin Laceration 44 1.7 1.7 no signal
215 Hyperlipidaemia 48 1.7 1.7 no signal
216 Depression 908 1.7 1.7 no signal
217 Vulvovaginal Pain 19 1.7 1.7 no signal
218 Mood Altered 107 1.7 1.7 no signal
219 Psychiatric Symptom 29 1.7 1.7 no signal
220 Thrombosis 315 1.7 1.7 no signal
221 Hyperkeratosis 21 1.6 1.6 no signal
222 Hyperacusis 14 1.6 1.6 no signal
223 Abdominal Pain Lower 95 1.6 1.6 no signal
224 Weight Fluctuation 39 1.6 1.6 no signal
225 Ear Pruritus 13 1.6 1.6 no signal
226 Weight Loss Poor 17 1.6 1.6 no signal
227 Hyperreflexia 13 1.6 1.6 no signal
228 Weight Increased 821 1.6 1.6 no signal
229 Homicidal Ideation 15 1.6 1.6 no signal
230 Cardiac Murmur 32 1.6 1.6 no signal
231 Drug Dose Omission By Device 281 1.6 1.6 no signal
232 Skin Atrophy 21 1.6 1.6 no signal
233 Low Density Lipoprotein Increased 28 1.5 1.5 no signal
234 Visual Disturbance 21 1.5 1.5 no signal
235 Blood Prolactin Increased 17 1.5 1.5 no signal
236 Migraine 340 1.5 1.5 no signal
237 Post-traumatic Stress Disorder 24 1.5 1.5 no signal
238 Endocarditis 18 1.5 1.5 no signal
239 Chemotherapy 13 1.5 1.5 no signal
240 Neutrophil Count Increased 36 1.5 1.5 no signal
241 Maternal Drugs Affecting Foetus 27 1.5 1.5 no signal
242 Blood Iron Decreased 41 1.5 1.5 no signal
243 Muscle Strain 30 1.5 1.5 no signal
244 Hypercholesterolaemia 33 1.5 1.5 no signal
245 Dental Caries 38 1.5 1.5 no signal
246 Thyroid Disorder 53 1.5 1.5 no signal
247 Melanocytic Naevus 15 1.4 1.4 no signal
248 Irritable Bowel Syndrome 73 1.4 1.4 no signal
249 Ligament Rupture 15 1.4 1.4 no signal
250 Panic Attack 123 1.4 1.4 no signal
251 Mitral Valve Incompetence 38 1.4 1.4 no signal
252 Hot Flush 251 1.4 1.4 no signal
253 Blood Cholesterol Increased 155 1.4 1.4 no signal
254 Bone Disorder 61 1.4 1.4 no signal
255 Nerve Injury 37 1.4 1.4 no signal
256 Epigastric Discomfort 13 1.4 1.4 no signal
257 Tricuspid Valve Incompetence 26 1.4 1.4 no signal
258 Tonsillitis 17 1.4 1.4 no signal
259 Infusion Site Erythema 27 1.4 1.4 no signal
260 Meniscus Injury 20 1.4 1.4 no signal
261 Gastroenteritis 47 1.4 1.4 no signal
262 Diabetic Neuropathy 16 1.4 1.4 no signal
263 Emotional Disorder 99 1.4 1.4 no signal
264 Vitamin D Deficiency 31 1.3 1.3 no signal
265 Exostosis 29 1.3 1.3 no signal
266 Pharyngolaryngeal Pain 17 1.3 1.3 no signal
267 Toothache 57 1.3 1.3 no signal
268 Renal Cyst 25 1.3 1.3 no signal
269 Subcutaneous Abscess 15 1.3 1.3 no signal
270 Tic 17 1.3 1.3 no signal
271 Osteoarthritis 132 1.3 1.3 no signal
272 Wrong Drug Administered 28 1.3 1.3 no signal
273 Laryngeal Oedema 19 1.3 1.3 no signal
274 Breast Cancer Stage I 29 1.3 1.3 no signal
275 Papilloedema 14 1.3 1.3 no signal
276 Menstruation Delayed 32 1.3 1.3 no signal
277 Device Physical Property Issue 23 1.3 1.3 no signal
278 Crying 112 1.3 1.3 no signal
279 Medical Device Complication 23 1.3 1.3 no signal
280 Tenderness 32 1.3 1.3 no signal
281 Cholelithiasis 100 1.3 1.3 no signal
282 Hereditary Angioedema 32 1.3 1.3 no signal
283 Poor Quality Drug Administered 20 1.3 1.3 no signal
284 Fibromyalgia 73 1.3 1.3 no signal
285 Cholecystectomy 34 1.3 1.3 no signal
286 Infusion Site Pain 38 1.3 1.3 no signal
287 Anger 101 1.3 1.3 no signal
288 Mouth Swelling 17 1.3 1.3 no signal
289 Gingival Swelling 13 1.2 1.2 no signal
290 Haemorrhoids 57 1.2 1.2 no signal
291 Injection Site Discolouration 36 1.2 1.2 no signal
292 Peripheral Vascular Disorder 15 1.2 1.2 no signal
293 Night Sweats 93 1.2 1.2 no signal
294 Haemoglobin Increased 13 1.2 1.2 no signal
295 Impaired Work Ability 61 1.2 1.2 no signal
296 Exposure Via Skin Contact 64 1.2 1.2 no signal
297 Food Craving 14 1.2 1.2 no signal
298 Micturition Urgency 32 1.2 1.2 no signal
299 Hand Fracture 20 1.2 1.2 no signal
300 Cerebrovascular Accident 472 1.2 1.2 no signal
301 Device Breakage 109 1.2 1.2 no signal
302 Pregnancy With Contraceptive Device 25 1.2 1.2 no signal
303 Anxiety 788 1.2 1.2 no signal
304 Device Issue 241 1.2 1.2 no signal
305 Haemorrhage 287 1.2 1.2 no signal
306 Angina Unstable 18 1.2 1.2 no signal
307 Product Physical Consistency Issue 15 1.2 1.2 no signal
308 Deafness Unilateral 15 1.2 1.2 no signal
309 Iron Deficiency Anaemia 25 1.2 1.2 no signal
310 Supraventricular Tachycardia 26 1.2 1.2 no signal
311 Transient Ischaemic Attack 92 1.1 1.1 no signal
312 Wrong Product Administered 18 1.1 1.1 no signal
313 Ankle Fracture 42 1.1 1.1 no signal
314 Respiratory Rate Increased 24 1.1 1.1 no signal
315 Obesity 43 1.1 1.1 no signal
316 Activities Of Daily Living Impaired 54 1.1 1.1 no signal
317 Pain In Jaw 76 1.1 1.1 no signal
318 Photophobia 50 1.1 1.1 no signal
319 Sleep Apnoea Syndrome 51 1.1 1.1 no signal
320 Oral Mucosal Blistering 17 1.1 1.1 no signal
321 Abortion Induced 25 1.1 1.1 no signal
322 Cholecystitis Acute 15 1.1 1.1 no signal
323 General Physical Condition Abnormal 18 1.1 1.1 no signal
324 Mass 37 1.1 1.1 no signal
325 Embedded Device 26 1.1 1.1 no signal
326 Neoplasm 30 1.1 1.1 no signal
327 Affect Lability 25 1.1 1.1 no signal
328 Sciatica 41 1.1 1.1 no signal
329 Atelectasis 25 1.1 1.1 no signal
330 Mental Disorder 112 1.1 1.1 no signal
331 Bursitis 31 1.1 1.1 no signal
332 Device Delivery System Issue 67 1.1 1.1 no signal
333 Nocturia 31 1.1 1.1 no signal
334 Nervousness 134 1.1 1.1 no signal
335 Affective Disorder 20 1.1 1.1 no signal
336 Cold Sweat 45 1.1 1.1 no signal
337 Suicidal Ideation 233 1.1 1.1 no signal
338 Inflammatory Bowel Disease 25 1.1 1.1 no signal
339 Odynophagia 15 1.1 1.1 no signal
340 Cholecystitis 30 1.1 1.1 no signal
341 Food Allergy 19 1.1 1.1 no signal
342 Hypothyroidism 80 1.1 1.1 no signal
343 Blood Pressure Systolic Increased 49 1.1 1.1 no signal
344 Pharyngeal Oedema 39 1.1 1.1 no signal
345 Panic Reaction 18 1.1 1.1 no signal
346 Compression Fracture 13 1.1 1.1 no signal
347 Cyst 31 1.1 1.1 no signal
348 Joint Dislocation 26 1.0 1.0 no signal
349 Hiatus Hernia 32 1.0 1.0 no signal
350 Formication 17 1.0 1.0 no signal
351 Hypertonia 14 1.0 1.0 no signal
352 Foot Deformity 27 1.0 1.0 no signal
353 Wrist Fracture 29 1.0 1.0 no signal
354 Hidradenitis 21 1.0 1.0 no signal
355 Metabolic Disorder 14 1.0 1.0 no signal
356 Pharyngitis 30 1.0 1.0 no signal
357 Pharyngeal Swelling 23 1.0 1.0 no signal
358 Parosmia 18 1.0 1.0 no signal
359 Metastases To Bone 39 1.0 1.0 no signal
360 Depressed Mood 125 1.0 1.0 no signal
361 Irritability 143 1.0 1.0 no signal
362 Platelet Count Increased 31 1.0 1.0 no signal
363 Carpal Tunnel Syndrome 33 1.0 1.0 no signal
364 Post Procedural Complication 45 1.0 1.0 no signal
365 Device Deployment Issue 28 1.0 1.0 no signal
366 Onychoclasis 16 1.0 1.0 no signal
367 Blood Urine Present 44 1.0 1.0 no signal
368 Hunger 31 1.0 1.0 no signal
369 Abdominal Distension 237 1.0 1.0 no signal
370 Diabetes Mellitus 174 1.0 1.0 no signal
371 Economic Problem 35 1.0 1.0 no signal
372 Arteriosclerosis Coronary Artery 15 1.0 1.0 no signal
373 Urinary Incontinence 67 1.0 1.0 no signal
374 Lip Swelling 75 1.0 1.0 no signal
375 Blood Triglycerides Increased 40 1.0 1.0 no signal
376 Disturbance In Attention 122 1.0 1.0 no signal
377 Abdominal Pain 522 1.0 0.9 no signal
378 Joint Range Of Motion Decreased 30 0.9 0.9 no signal
379 Grand Mal Convulsion 21 0.9 0.9 no signal
380 Ligament Sprain 22 0.9 0.9 no signal
381 Arteriosclerosis 21 0.9 0.9 no signal
382 Throat Tightness 60 0.9 0.9 no signal
383 Photopsia 14 0.9 0.9 no signal
384 Fear 60 0.9 0.9 no signal
385 Gastrooesophageal Reflux Disease 177 0.9 0.9 no signal
386 Drug Ineffective For Unapproved Indication 123 0.9 0.9 no signal
387 Inappropriate Schedule Of Drug Administration 159 0.9 0.9 no signal
388 Blindness Unilateral 31 0.9 0.9 no signal
389 Multiple Injuries 14 0.9 0.9 no signal
390 Respiration Abnormal 15 0.9 0.9 no signal
391 Mania 36 0.9 0.9 no signal
392 Procedural Pain 60 0.9 0.9 no signal
393 Device Dislocation 94 0.9 0.9 no signal
394 Occupational Exposure To Product 14 0.9 0.9 no signal
395 Cardiac Flutter 14 0.9 0.9 no signal
396 Tooth Abscess 22 0.9 0.9 no signal
397 Intervertebral Disc Protrusion 47 0.9 0.9 no signal
398 Abscess 34 0.9 0.9 no signal
399 Systemic Lupus Erythematosus 75 0.9 0.9 no signal
400 Ventricular Extrasystoles 22 0.9 0.9 no signal
401 Anaphylactic Reaction 116 0.9 0.9 no signal
402 Cardiomegaly 26 0.9 0.9 no signal
403 Muscle Disorder 17 0.9 0.9 no signal
404 Pharmaceutical Product Complaint 55 0.9 0.9 no signal
405 Paraesthesia Oral 30 0.9 0.9 no signal
406 Tooth Fracture 23 0.9 0.9 no signal
407 Product Administration Interrupted 16 0.9 0.9 no signal
408 Visual Field Defect 15 0.9 0.9 no signal
409 Stress 149 0.9 0.9 no signal
410 Acne 157 0.9 0.9 no signal
411 Maternal Exposure Before Pregnancy 14 0.9 0.9 no signal
412 Hypoaesthesia 305 0.9 0.9 no signal
413 Injection Site Discomfort 21 0.9 0.9 no signal
414 Peripheral Coldness 28 0.9 0.9 no signal
415 Spinal Compression Fracture 17 0.9 0.9 no signal
416 Increased Appetite 38 0.9 0.9 no signal
417 Facial Pain 18 0.9 0.9 no signal
418 Upper Respiratory Tract Infection 93 0.9 0.9 no signal
419 Neck Pain 112 0.8 0.8 no signal
420 Anhedonia 53 0.8 0.8 no signal
421 Hyperprolactinaemia 13 0.8 0.8 no signal
422 Nodule 26 0.8 0.8 no signal
423 Pollakiuria 82 0.8 0.8 no signal
424 Convulsion 114 0.8 0.8 no signal
425 Joint Injury 42 0.8 0.8 no signal
426 Initial Insomnia 20 0.8 0.8 no signal
427 Hypersomnia 56 0.8 0.8 no signal
428 Nerve Compression 18 0.8 0.8 no signal
429 Upper-airway Cough Syndrome 16 0.8 0.8 no signal
430 Blood Thyroid Stimulating Hormone Increased 18 0.8 0.8 no signal
431 Hemiparesis 33 0.8 0.8 no signal
432 Injection Site Induration 25 0.8 0.8 no signal
433 Fluid Retention 98 0.8 0.8 no signal
434 Personality Change 18 0.8 0.8 no signal
435 Flank Pain 18 0.8 0.8 no signal
436 Pulmonary Thrombosis 21 0.8 0.8 no signal
437 Sinus Disorder 38 0.8 0.8 no signal
438 Embolism 16 0.8 0.8 no signal
439 Road Traffic Accident 80 0.8 0.8 no signal
440 Bone Loss 29 0.8 0.8 no signal
441 Paranoia 33 0.8 0.8 no signal
442 Eye Movement Disorder 13 0.8 0.8 no signal
443 Blood Albumin Decreased 15 0.8 0.8 no signal
444 Furuncle 15 0.8 0.8 no signal
445 Aggression 95 0.8 0.8 no signal
446 Amnesia 123 0.8 0.8 no signal
447 Hepatic Steatosis 35 0.8 0.8 no signal
448 Cerebral Infarction 46 0.8 0.8 no signal
449 Osteomyelitis 34 0.8 0.8 no signal
450 Incorrect Route Of Drug Administration 68 0.8 0.8 no signal
451 Musculoskeletal Chest Pain 29 0.8 0.8 no signal
452 Blood Pressure Fluctuation 45 0.8 0.8 no signal
453 Emotional Distress 227 0.8 0.8 no signal
454 Vitamin D Decreased 16 0.8 0.8 no signal
455 Generalised Oedema 23 0.8 0.8 no signal
456 Hypercalcaemia 23 0.8 0.8 no signal
457 Obsessive-compulsive Disorder 15 0.8 0.8 no signal
458 Sinusitis 191 0.8 0.8 no signal
459 Sensory Loss 15 0.8 0.8 no signal
460 Arthritis 146 0.8 0.8 no signal
461 Chest Pain 343 0.8 0.8 no signal
462 Heart Rate Irregular 42 0.8 0.8 no signal
463 Bronchitis 137 0.8 0.8 no signal
464 Anorexia 24 0.8 0.8 no signal
465 Type 2 Diabetes Mellitus 62 0.8 0.8 no signal
466 Sinus Tachycardia 26 0.8 0.8 no signal
467 Sneezing 41 0.8 0.8 no signal
468 Immunodeficiency 27 0.8 0.8 no signal
469 Back Pain 425 0.8 0.8 no signal
470 Bedridden 24 0.8 0.8 no signal
471 Complication Of Device Removal 31 0.8 0.8 no signal
472 Syncope 182 0.8 0.8 no signal
473 Concussion 14 0.8 0.8 no signal
474 Bone Pain 106 0.8 0.8 no signal
475 Alopecia 355 0.8 0.8 no signal
476 Rib Fracture 37 0.8 0.8 no signal
477 Ear Pain 35 0.8 0.8 no signal
478 Sexual Dysfunction 21 0.8 0.8 no signal
479 Hyperthyroidism 26 0.8 0.8 no signal
480 Hemiplegia 15 0.8 0.8 no signal
481 Pallor 49 0.8 0.8 no signal
482 Palpitations 210 0.8 0.8 no signal
483 Basal Cell Carcinoma 28 0.8 0.8 no signal
484 Obstructive Airways Disorder 20 0.8 0.8 no signal
485 Urticaria 298 0.8 0.8 no signal
486 Caesarean Section 21 0.8 0.8 no signal
487 Nightmare 62 0.8 0.8 no signal
488 Electrocardiogram Abnormal 14 0.8 0.8 no signal
489 Muscle Spasticity 22 0.8 0.8 no signal
490 Sinus Congestion 24 0.8 0.8 no signal
491 Insomnia 470 0.7 0.7 no signal
492 Restless Legs Syndrome 32 0.7 0.7 no signal
493 Pharyngitis Streptococcal 19 0.7 0.7 no signal
494 Optic Neuritis 16 0.7 0.7 no signal
495 Poor Venous Access 18 0.7 0.7 no signal
496 Hypertension 369 0.7 0.7 no signal
497 Complication Associated With Device 23 0.7 0.7 no signal
498 Rhinitis 14 0.7 0.7 no signal
499 Kidney Infection 34 0.7 0.7 no signal
500 Muscle Spasms 318 0.7 0.7 no signal
501 Poor Quality Sleep 37 0.7 0.7 no signal
502 Hypoaesthesia Oral 26 0.7 0.7 no signal
503 Vertigo 105 0.7 0.7 no signal
504 Device Malfunction 115 0.7 0.7 no signal
505 Metastases To Liver 30 0.7 0.7 no signal
506 Malnutrition 19 0.7 0.7 no signal
507 Bladder Disorder 17 0.7 0.7 no signal
508 Diarrhoea Haemorrhagic 16 0.7 0.7 no signal
509 Rotator Cuff Syndrome 22 0.7 0.7 no signal
510 Diverticulitis 47 0.7 0.7 no signal
511 Tooth Disorder 38 0.7 0.7 no signal
512 Seasonal Allergy 24 0.7 0.7 no signal
513 Incontinence 18 0.7 0.7 no signal
514 Hallucination, Auditory 27 0.7 0.7 no signal
515 Localised Infection 41 0.7 0.7 no signal
516 Maternal Exposure During Pregnancy 149 0.7 0.7 no signal
517 Therapeutic Response Unexpected 76 0.7 0.7 no signal
518 Feeling Cold 47 0.7 0.7 no signal
519 Psychomotor Hyperactivity 28 0.7 0.7 no signal
520 Impaired Healing 55 0.7 0.7 no signal
521 Gastritis 44 0.7 0.7 no signal
522 Muscle Rigidity 20 0.7 0.7 no signal
523 Dermatitis Contact 19 0.7 0.7 no signal
524 Adrenal Insufficiency 20 0.7 0.7 no signal
525 Impaired Driving Ability 19 0.7 0.7 no signal
526 Muscle Tightness 27 0.7 0.7 no signal
527 Congenital Anomaly 13 0.7 0.7 no signal
528 Myocardial Infarction 290 0.7 0.7 no signal
529 Tachycardia 145 0.7 0.7 no signal
530 Pain 1,002 0.7 0.7 no signal
531 Tooth Loss 34 0.7 0.7 no signal
532 Dysuria 60 0.7 0.7 no signal
533 Heart Rate Increased 161 0.7 0.7 no signal
534 Mental Status Changes 45 0.7 0.7 no signal
535 Sleep Disorder 113 0.7 0.7 no signal
536 Nail Disorder 14 0.7 0.7 no signal
537 Headache 1,008 0.7 0.7 no signal
538 Retching 34 0.7 0.7 no signal
539 Swelling 149 0.7 0.7 no signal
540 Muscle Atrophy 20 0.7 0.7 no signal
541 Recalled Product Administered 14 0.7 0.7 no signal
542 Drug Administered At Inappropriate Site 17 0.7 0.7 no signal
543 Tinnitus 73 0.7 0.7 no signal
544 Apathy 23 0.7 0.7 no signal
545 Skin Lesion 43 0.7 0.7 no signal
546 Conjunctivitis 29 0.7 0.7 no signal
547 Femur Fracture 49 0.7 0.7 no signal
548 Arrhythmia 75 0.7 0.7 no signal
549 Body Height Decreased 17 0.7 0.7 no signal
550 Hyperaesthesia 13 0.7 0.7 no signal
551 Back Injury 17 0.7 0.7 no signal
552 Myocardial Ischaemia 18 0.7 0.7 no signal
553 Neuralgia 38 0.7 0.7 no signal
554 Lethargy 90 0.7 0.7 no signal
555 Body Temperature Increased 32 0.7 0.7 no signal
556 Quality Of Life Decreased 21 0.7 0.7 no signal
557 Metastases To Central Nervous System 20 0.7 0.7 no signal
558 Device Use Issue 27 0.7 0.7 no signal
559 Device Related Infection 24 0.7 0.7 no signal
560 Cardiomyopathy 23 0.7 0.7 no signal
561 Eating Disorder 33 0.7 0.7 no signal
562 Tendonitis 24 0.7 0.7 no signal
563 Coronary Artery Disease 47 0.7 0.7 no signal
564 Oedema Peripheral 188 0.7 0.6 no signal
565 Gingival Bleeding 21 0.6 0.6 no signal
566 Coeliac Disease 15 0.6 0.6 no signal
567 Generalised Tonic-clonic Seizure 25 0.6 0.6 no signal
568 Local Swelling 27 0.6 0.6 no signal
569 Hyperhidrosis 196 0.6 0.6 no signal
570 Body Temperature Decreased 15 0.6 0.6 no signal
571 Spinal Fracture 30 0.6 0.6 no signal
572 Coagulopathy 25 0.6 0.6 no signal
573 Feeling Hot 92 0.6 0.6 no signal
574 Dizziness 746 0.6 0.6 no signal
575 Cellulitis 75 0.6 0.6 no signal
576 Pulmonary Hypertension 31 0.6 0.6 no signal
577 Sputum Discoloured 14 0.6 0.6 no signal
578 Fracture 28 0.6 0.6 no signal
579 Fungal Infection 49 0.6 0.6 no signal
580 Nephrolithiasis 67 0.6 0.6 no signal
581 Oesophagitis 16 0.6 0.6 no signal
582 Impaired Quality Of Life 21 0.6 0.6 no signal
583 Deafness 38 0.6 0.6 no signal
584 Pain In Extremity 428 0.6 0.6 no signal
585 Device Failure 22 0.6 0.6 no signal
586 Wrong Technique In Device Usage Process 66 0.6 0.6 no signal
587 Loss Of Consciousness 185 0.6 0.6 no signal
588 Injection Site Reaction 99 0.6 0.6 no signal
589 Synovitis 26 0.6 0.6 no signal
590 Limb Injury 39 0.6 0.6 no signal
591 Liver Function Test Abnormal 42 0.6 0.6 no signal
592 White Blood Cell Count Increased 55 0.6 0.6 no signal
593 Renal Pain 15 0.6 0.6 no signal
594 Blood Calcium Decreased 16 0.6 0.6 no signal
595 Pulmonary Mass 21 0.6 0.6 no signal
596 Serotonin Syndrome 27 0.6 0.6 no signal
597 Epilepsy 43 0.6 0.6 no signal
598 Presyncope 34 0.6 0.6 no signal
599 Haematocrit Decreased 28 0.6 0.6 no signal
600 Arthropathy 78 0.6 0.6 no signal
601 Contusion 133 0.6 0.6 no signal
602 Lymphadenopathy 49 0.6 0.6 no signal
603 Musculoskeletal Pain 73 0.6 0.6 no signal
604 Feeling Abnormal 332 0.6 0.6 no signal
605 Mouth Ulceration 29 0.6 0.6 no signal
606 Swollen Tongue 43 0.6 0.6 no signal
607 Chest Discomfort 140 0.6 0.6 no signal
608 Injection Site Swelling 104 0.6 0.6 no signal
609 Incorrect Route Of Product Administration 23 0.6 0.6 no signal
610 Tooth Extraction 17 0.6 0.6 no signal
611 Movement Disorder 44 0.6 0.6 no signal
612 Paraesthesia 215 0.6 0.6 no signal
613 Treatment Noncompliance 74 0.6 0.6 no signal
614 Abnormal Behaviour 54 0.6 0.6 no signal
615 Abdominal Pain Upper 278 0.6 0.6 no signal
616 Blood Test Abnormal 19 0.6 0.6 no signal
617 Skin Disorder 45 0.6 0.6 no signal
618 Weight Decreased 377 0.6 0.6 no signal
619 Diplopia 35 0.6 0.6 no signal
620 Urinary Tract Infection 229 0.6 0.6 no signal
621 Nausea 1,059 0.6 0.6 no signal
622 Seizure 154 0.6 0.6 no signal
623 Hypersensitivity 248 0.6 0.6 no signal
624 Photosensitivity Reaction 22 0.6 0.6 no signal
625 Thinking Abnormal 25 0.6 0.6 no signal
626 Osteonecrosis 44 0.6 0.6 no signal
627 Blindness 54 0.6 0.6 no signal
628 Status Epilepticus 15 0.6 0.6 no signal
629 Colitis Ulcerative 59 0.6 0.6 no signal
630 Asthma 148 0.6 0.6 no signal
631 Ear Infection 35 0.6 0.6 no signal
632 Cystitis 42 0.6 0.6 no signal
633 Musculoskeletal Disorder 25 0.6 0.6 no signal
634 Skin Discolouration 60 0.6 0.6 no signal
635 Vomiting 610 0.6 0.5 no signal
636 Salivary Hypersecretion 13 0.6 0.6 no signal
637 Upper Limb Fracture 26 0.5 0.5 no signal
638 Diabetes Mellitus Inadequate Control 23 0.5 0.5 no signal
639 Brain Injury 13 0.5 0.5 no signal
640 Aspiration 14 0.5 0.5 no signal
641 Aphonia 18 0.5 0.5 no signal
642 Tooth Infection 17 0.5 0.5 no signal
643 Emphysema 13 0.5 0.5 no signal
644 Myalgia 218 0.5 0.5 no signal
645 Tremor 213 0.5 0.5 no signal
646 Condition Aggravated 384 0.5 0.5 no signal
647 Staphylococcal Infection 42 0.5 0.5 no signal
648 Vision Blurred 173 0.5 0.5 no signal
649 Restlessness 46 0.5 0.5 no signal
650 Visual Acuity Reduced 42 0.5 0.5 no signal
651 Dizziness Postural 12 0.5 0.5 no signal
652 Agitation 92 0.5 0.5 no signal
653 Arthralgia 517 0.5 0.5 no signal
654 Swelling Face 81 0.5 0.5 no signal
655 Medication Error 69 0.5 0.5 no signal
656 Drug Hypersensitivity 241 0.5 0.5 no signal
657 Complication Of Device Insertion 23 0.5 0.5 no signal
658 Middle Insomnia 23 0.5 0.5 no signal
659 Brain Fog 18 0.5 0.5 no signal
660 Viral Infection 41 0.5 0.5 no signal
661 Oral Candidiasis 16 0.5 0.5 no signal
662 Blood Pressure Increased 188 0.5 0.5 no signal
663 Drug Dispensing Error 19 0.5 0.5 no signal
664 Back Disorder 20 0.5 0.5 no signal
665 Somnolence 246 0.5 0.5 no signal
666 Dysarthria 46 0.5 0.5 no signal
667 Aphasia 37 0.5 0.5 no signal
668 Musculoskeletal Discomfort 21 0.5 0.5 no signal
669 Proteinuria 23 0.5 0.5 no signal
670 Rash Generalised 32 0.5 0.5 no signal
671 Gastroenteritis Viral 22 0.5 0.5 no signal
672 Osteonecrosis Of Jaw 30 0.5 0.5 no signal
673 Dermatitis Allergic 15 0.5 0.5 no signal
674 Balance Disorder 104 0.5 0.5 no signal
675 Nasal Congestion 70 0.5 0.5 no signal
676 Injection Site Mass 44 0.5 0.5 no signal
677 Increased Tendency To Bruise 11 0.5 0.5 no signal
678 Drug Administration Error 37 0.5 0.5 no signal
679 Inflammation 61 0.5 0.5 no signal
680 Pruritus Generalised 26 0.5 0.5 no signal
681 Chills 139 0.5 0.5 no signal
682 Hip Fracture 38 0.5 0.5 no signal
683 Injection Site Nodule 13 0.5 0.5 no signal
684 Oral Herpes 23 0.5 0.5 no signal
685 Oxygen Saturation Decreased 66 0.5 0.5 no signal
686 Dry Throat 12 0.5 0.5 no signal
687 Oropharyngeal Pain 109 0.5 0.5 no signal
688 Impaired Gastric Emptying 15 0.5 0.5 no signal
689 Dyspepsia 115 0.5 0.5 no signal
690 Anaphylactic Shock 30 0.5 0.5 no signal
691 Spinal Disorder 11 0.5 0.5 no signal
692 Rash Papular 26 0.5 0.5 no signal
693 Abasia 29 0.5 0.5 no signal
694 Surgery 67 0.5 0.5 no signal
695 Memory Impairment 159 0.5 0.5 no signal
696 Gastric Ulcer 22 0.5 0.5 no signal
697 General Physical Health Deterioration 132 0.5 0.5 no signal
698 Hallucination, Visual 24 0.5 0.5 no signal
699 Joint Stiffness 30 0.5 0.5 no signal
700 Musculoskeletal Stiffness 100 0.5 0.5 no signal
701 Cognitive Disorder 53 0.5 0.5 no signal
702 Skin Reaction 16 0.5 0.5 no signal
703 Anaemia 217 0.5 0.5 no signal
704 Asthenia 425 0.5 0.5 no signal
705 Fatigue 876 0.5 0.5 no signal
706 Metastases To Lung 13 0.5 0.5 no signal
707 Thirst 20 0.5 0.5 no signal
708 Dyspnoea 634 0.5 0.5 no signal
709 Red Blood Cell Count Decreased 32 0.5 0.5 no signal
710 Psychotic Disorder 33 0.5 0.5 no signal
711 Device Use Error 38 0.5 0.5 no signal
712 Post Procedural Haemorrhage 13 0.5 0.5 no signal
713 Splenomegaly 13 0.5 0.5 no signal
714 Eye Swelling 41 0.5 0.5 no signal
715 Muscular Weakness 126 0.5 0.5 no signal
716 Infusion Related Reaction 73 0.5 0.5 no signal
717 Lower Limb Fracture 21 0.5 0.5 no signal
718 Rash Pruritic 59 0.5 0.5 no signal
719 Premature Baby 33 0.5 0.5 no signal
720 Intentional Self-injury 22 0.5 0.5 no signal
721 Visual Impairment 134 0.5 0.5 no signal
722 Injection Site Pain 330 0.5 0.5 no signal
723 Blood Alkaline Phosphatase Increased 27 0.5 0.5 no signal
724 Burning Sensation 76 0.5 0.5 no signal
725 Product Quality Issue 146 0.5 0.5 no signal
726 Subarachnoid Haemorrhage 11 0.5 0.5 no signal
727 Sickle Cell Anaemia With Crisis 17 0.5 0.5 no signal
728 Poor Quality Product Administered 11 0.5 0.5 no signal
729 Lymphocyte Count Decreased 19 0.5 0.5 no signal
730 Drug Interaction 170 0.5 0.5 no signal
731 Coordination Abnormal 15 0.5 0.5 no signal
732 Rectal Haemorrhage 46 0.5 0.5 no signal
733 Influenza 119 0.4 0.4 no signal
734 Disability 21 0.4 0.4 no signal
735 Scab 12 0.4 0.4 no signal
736 Petechiae 11 0.4 0.4 no signal
737 Blood Pressure Decreased 70 0.4 0.4 no signal
738 Loss Of Personal Independence In Daily Activities 50 0.4 0.4 no signal
739 Incorrect Dose Administered 236 0.4 0.4 no signal
740 Drug Intolerance 101 0.4 0.4 no signal
741 Laceration 10 0.4 0.4 no signal
742 Exposure During Pregnancy 65 0.4 0.4 no signal
743 Nasopharyngitis 193 0.4 0.4 no signal
744 Autoimmune Disorder 10 0.4 0.4 no signal
745 Paralysis 15 0.4 0.4 no signal
746 Wound 29 0.4 0.4 no signal
747 Respiratory Arrest 29 0.4 0.4 no signal
748 Angioedema 46 0.4 0.4 no signal
749 Dyspnoea Exertional 39 0.4 0.4 no signal
750 Muscle Twitching 24 0.4 0.4 no signal
751 Lymphoma 16 0.4 0.4 no signal
752 Unevaluable Event 78 0.4 0.4 no signal
753 Hypoxia 36 0.4 0.4 no signal
754 Spinal Pain 12 0.4 0.4 no signal
755 Decreased Immune Responsiveness 10 0.4 0.4 no signal
756 Haemoglobin Decreased 105 0.4 0.4 no signal
757 Suicide Attempt 62 0.4 0.4 no signal
758 Dehydration 136 0.4 0.4 no signal
759 Candida Infection 17 0.4 0.4 no signal
760 Coronary Artery Occlusion 14 0.4 0.4 no signal
761 Cyanosis 16 0.4 0.4 no signal
762 Dermatitis 21 0.4 0.4 no signal
763 Hepatomegaly 10 0.4 0.4 no signal
764 Herpes Zoster 58 0.4 0.4 no signal
765 Angina Pectoris 29 0.4 0.4 no signal
766 Rash Macular 35 0.4 0.4 no signal
767 Rash Erythematous 47 0.4 0.4 no signal
768 Device Difficult To Use 66 0.4 0.4 no signal
769 Wheezing 59 0.4 0.4 no signal
770 Product Use Issue 186 0.4 0.4 no signal
771 Injury Associated With Device 20 0.4 0.4 no signal
772 Dysphagia 94 0.4 0.4 no signal
773 Infection 143 0.4 0.4 no signal
774 Nervous System Disorder 31 0.4 0.4 no signal
775 Hypotension 198 0.4 0.4 no signal
776 Injection Site Rash 30 0.4 0.4 no signal
777 Pruritus 372 0.4 0.4 no signal
778 Eyelid Ptosis 10 0.4 0.4 no signal
779 Pulmonary Congestion 13 0.4 0.4 no signal
780 Incorrect Drug Administration Duration 28 0.4 0.4 no signal
781 Gait Disturbance 188 0.4 0.4 no signal
782 Bronchospasm 14 0.4 0.4 no signal
783 Incorrect Product Storage 13 0.4 0.4 no signal
784 Speech Disorder 51 0.4 0.4 no signal
785 Lacrimation Increased 29 0.4 0.4 no signal
786 Dry Eye 47 0.4 0.4 no signal
787 Limb Discomfort 30 0.4 0.4 no signal
788 Bacterial Infection 18 0.4 0.4 no signal
789 Appendicitis 9 0.4 0.4 no signal
790 Scratch 10 0.4 0.4 no signal
791 Pericarditis 16 0.4 0.4 no signal
792 Lung Disorder 47 0.4 0.4 no signal
793 Eye Pain 53 0.4 0.4 no signal
794 Hypokalaemia 44 0.4 0.4 no signal
795 Discomfort 58 0.4 0.4 no signal
796 Pericardial Effusion 22 0.4 0.4 no signal
797 Flatulence 54 0.4 0.4 no signal
798 Malaise 418 0.4 0.4 no signal
799 Mental Impairment 23 0.4 0.4 no signal
800 Joint Swelling 114 0.4 0.4 no signal
801 Central Nervous System Lesion 13 0.4 0.4 no signal
802 Oral Discomfort 13 0.4 0.4 no signal
803 Haemoptysis 26 0.4 0.4 no signal
804 Sinus Bradycardia 9 0.4 0.4 no signal
805 Choking 18 0.4 0.4 no signal
806 Cardiac Disorder 87 0.4 0.4 no signal
807 Oedema 50 0.4 0.4 no signal
808 Haematoma 24 0.4 0.4 no signal
809 Myoclonus 11 0.4 0.4 no signal
810 Flushing 94 0.4 0.4 no signal
811 Confusional State 149 0.4 0.4 no signal
812 Head Injury 29 0.4 0.4 no signal
813 Fall 304 0.4 0.4 no signal
814 Dry Mouth 74 0.4 0.4 no signal
815 Decreased Appetite 211 0.4 0.4 no signal
816 Hyperglycaemia 33 0.4 0.4 no signal
817 Head Discomfort 16 0.4 0.4 no signal
818 Heart Rate Decreased 32 0.4 0.4 no signal
819 Multiple Fractures 15 0.4 0.4 no signal
820 Haematuria 31 0.4 0.4 no signal
821 Gamma-glutamyltransferase Increased 20 0.4 0.4 no signal
822 Injection Site Erythema 111 0.4 0.4 no signal
823 Ejection Fraction Decreased 14 0.4 0.4 no signal
824 Ventricular Fibrillation 10 0.4 0.4 no signal
825 Dementia 25 0.4 0.4 no signal
826 Stevens-johnson Syndrome 20 0.4 0.4 no signal
827 Small Intestinal Obstruction 11 0.4 0.4 no signal
828 Skin Infection 10 0.4 0.4 no signal
829 Illness 90 0.4 0.4 no signal
830 Influenza Like Illness 74 0.4 0.4 no signal
831 Ischaemic Stroke 16 0.4 0.4 no signal
832 Gastrointestinal Disorder 79 0.4 0.4 no signal
833 Hair Texture Abnormal 12 0.4 0.4 no signal
834 Haematochezia 49 0.4 0.4 no signal
835 Myocarditis 10 0.4 0.4 no signal
836 Abnormal Weight Gain 11 0.4 0.4 no signal
837 Disease Recurrence 42 0.4 0.4 no signal
838 Drug Level Decreased 9 0.4 0.4 no signal
839 Cough 246 0.4 0.4 no signal
840 Colitis 33 0.4 0.4 no signal
841 Electrolyte Imbalance 10 0.4 0.4 no signal
842 Respiratory Distress 24 0.4 0.4 no signal
843 Urosepsis 8 0.4 0.4 no signal
844 Neurotoxicity 15 0.4 0.4 no signal
845 Chronic Obstructive Pulmonary Disease 45 0.4 0.4 no signal
846 Dyskinesia 35 0.4 0.4 no signal
847 Cataract 51 0.4 0.4 no signal
848 Constipation 186 0.4 0.4 no signal
849 Vasculitis 10 0.4 0.4 no signal
850 Hip Arthroplasty 13 0.4 0.4 no signal
851 Transfusion 9 0.4 0.4 no signal
852 Injection Site Bruising 67 0.4 0.4 no signal
853 Drug Ineffective 1,118 0.4 0.3 no signal
854 Squamous Cell Carcinoma 8 0.4 0.4 no signal
855 Productive Cough 40 0.4 0.4 no signal
856 Ventricular Tachycardia 14 0.4 0.4 no signal
857 Sudden Death 9 0.4 0.4 no signal
858 Injection Site Pruritus 56 0.4 0.4 no signal
859 Epistaxis 63 0.4 0.4 no signal
860 Decreased Activity 9 0.4 0.4 no signal
861 Coma 40 0.4 0.4 no signal
862 Dysphonia 49 0.4 0.4 no signal
863 Pleural Effusion 51 0.4 0.4 no signal
864 Hernia 16 0.4 0.4 no signal
865 Accidental Exposure To Product 83 0.4 0.4 no signal
866 Leukocytosis 15 0.4 0.4 no signal
867 Laryngitis 9 0.4 0.4 no signal
868 Throat Irritation 37 0.3 0.3 no signal
869 Hypokinesia 12 0.3 0.3 no signal
870 Lung Infection 13 0.3 0.3 no signal
871 Injection Site Urticaria 20 0.3 0.3 no signal
872 Schizophrenia 10 0.3 0.3 no signal
873 Vitreous Floaters 8 0.3 0.3 no signal
874 Off Label Use 712 0.3 0.3 no signal
875 Pneumothorax 13 0.3 0.3 no signal
876 Intentional Product Misuse 71 0.3 0.3 no signal
877 Jaundice 22 0.3 0.3 no signal
878 Expired Product Administered 27 0.3 0.3 no signal
879 Ileus 10 0.3 0.3 no signal
880 Rash 352 0.3 0.3 no signal
881 Multiple Sclerosis 39 0.3 0.3 no signal
882 Secretion Discharge 10 0.3 0.3 no signal
883 Tendon Rupture 10 0.3 0.3 no signal
884 Blood Pressure Abnormal 16 0.3 0.3 no signal
885 Rhinorrhoea 52 0.3 0.3 no signal
886 Sensory Disturbance 13 0.3 0.3 no signal
887 Sedation 21 0.3 0.3 no signal
888 Erythema 165 0.3 0.3 no signal
889 Product Use In Unapproved Indication 196 0.3 0.3 no signal
890 Hypotonia 8 0.3 0.3 no signal
891 Abdominal Discomfort 133 0.3 0.3 no signal
892 Blood Creatinine Increased 52 0.3 0.3 no signal
893 Pancreatitis 42 0.3 0.3 no signal
894 Motor Dysfunction 8 0.3 0.3 no signal
895 Incorrect Product Administration Duration 16 0.3 0.3 no signal
896 Sluggishness 8 0.3 0.3 no signal
897 Temperature Intolerance 8 0.3 0.3 no signal
898 Cardiovascular Disorder 20 0.3 0.3 no signal
899 Cardiac Failure Congestive 63 0.3 0.3 no signal
900 Prescribed Overdose 15 0.3 0.3 no signal
901 Delusion 12 0.3 0.3 no signal
902 Skin Ulcer 20 0.3 0.3 no signal
903 Product Administered At Inappropriate Site 14 0.3 0.3 no signal
904 Peripheral Swelling 118 0.3 0.3 no signal
905 Eyelid Oedema 9 0.3 0.3 no signal
906 Blister 43 0.3 0.3 no signal
907 Device Expulsion 50 0.3 0.3 no signal
908 Pyrexia 265 0.3 0.3 no signal
909 Skin Haemorrhage 11 0.3 0.3 no signal
910 Glossodynia 17 0.3 0.3 no signal
911 Immune System Disorder 10 0.3 0.3 no signal
912 Disorientation 30 0.3 0.3 no signal
913 Ataxia 9 0.3 0.3 no signal
914 Clostridium Difficile Colitis 8 0.3 0.3 no signal
915 Ulcer 12 0.3 0.3 no signal
916 Product Physical Issue 15 0.3 0.3 no signal
917 Feeding Disorder 15 0.3 0.3 no signal
918 Multiple Sclerosis Relapse 52 0.3 0.3 no signal
919 Diabetic Ketoacidosis 18 0.3 0.3 no signal
920 Dysstasia 22 0.3 0.3 no signal
921 Injection Site Haematoma 11 0.3 0.3 no signal
922 Electrocardiogram Qt Prolonged 27 0.3 0.3 no signal
923 Intestinal Obstruction 28 0.3 0.3 no signal
924 Hallucination 56 0.3 0.3 no signal
925 Laboratory Test Abnormal 22 0.3 0.3 no signal
926 Psoriatic Arthropathy 30 0.3 0.3 no signal
927 Frequent Bowel Movements 20 0.3 0.3 no signal
928 Hepatitis C 9 0.3 0.3 no signal
929 Withdrawal Syndrome 31 0.3 0.3 no signal
930 Feeling Jittery 14 0.3 0.3 no signal
931 Drug Effect Decreased 40 0.3 0.3 no signal
932 Respiratory Tract Infection 19 0.3 0.3 no signal
933 Injection Site Warmth 15 0.3 0.3 no signal
934 Ocular Hyperaemia 34 0.3 0.3 no signal
935 Diarrhoea 464 0.3 0.3 no signal
936 Knee Operation 7 0.3 0.3 no signal
937 Abnormal Dreams 20 0.3 0.3 no signal
938 Skin Irritation 33 0.3 0.3 no signal
939 Product Prescribing Error 17 0.3 0.3 no signal
940 Gastric Disorder 25 0.3 0.3 no signal
941 Parkinsonism 7 0.3 0.3 no signal
942 Pancreatitis Acute 16 0.3 0.3 no signal
943 Intentional Product Use Issue 63 0.3 0.3 no signal
944 Aspartate Aminotransferase Increased 38 0.3 0.3 no signal
945 Eye Infection 8 0.3 0.3 no signal
946 Brain Oedema 9 0.3 0.3 no signal
947 Oral Pain 16 0.3 0.3 no signal
948 Face Oedema 12 0.3 0.3 no signal
949 Circulatory Collapse 12 0.3 0.3 no signal
950 Leukopenia 35 0.3 0.3 no signal
951 Mobility Decreased 50 0.3 0.3 no signal
952 Intentional Dose Omission 19 0.3 0.3 no signal
953 Injection Site Haemorrhage 55 0.3 0.3 no signal
954 Clostridium Difficile Infection 15 0.3 0.3 no signal
955 Respiratory Tract Congestion 11 0.3 0.3 no signal
956 Blood Sodium Decreased 13 0.3 0.3 no signal
957 Underdose 50 0.3 0.3 no signal
958 Depressed Level Of Consciousness 27 0.3 0.3 no signal
959 Ear Discomfort 7 0.3 0.3 no signal
960 Alanine Aminotransferase Increased 42 0.3 0.3 no signal
961 Adverse Drug Reaction 61 0.3 0.3 no signal
962 Pulmonary Fibrosis 13 0.3 0.3 no signal
963 Hypoglycaemia 33 0.3 0.3 no signal
964 Euphoric Mood 7 0.3 0.3 no signal
965 Fluid Overload 10 0.3 0.3 no signal
966 Glycosylated Haemoglobin Increased 17 0.3 0.3 no signal
967 Sars-cov-2 Test Positive 9 0.3 0.3 no signal
968 Knee Arthroplasty 14 0.3 0.3 no signal
969 Macular Degeneration 8 0.3 0.3 no signal
970 Malignant Melanoma 9 0.3 0.3 no signal
971 Hypophagia 17 0.3 0.3 no signal
972 Haematemesis 17 0.3 0.3 no signal
973 Drug Prescribing Error 13 0.3 0.3 no signal
974 Hepatitis 17 0.3 0.3 no signal
975 Therapeutic Response Shortened 21 0.3 0.3 no signal
976 Lung Neoplasm Malignant 27 0.3 0.3 no signal
977 Retinal Detachment 6 0.3 0.3 no signal
978 Blood Glucose Abnormal 12 0.3 0.3 no signal
979 Ascites 19 0.3 0.3 no signal
980 Acute Myocardial Infarction 19 0.3 0.3 no signal
981 Injection Site Extravasation 8 0.3 0.3 no signal
982 Nephropathy 6 0.3 0.3 no signal
983 Eczema 32 0.3 0.3 no signal
984 Hair Colour Changes 8 0.3 0.3 no signal
985 Injection Site Irritation 8 0.3 0.3 no signal
986 Liver Disorder 28 0.3 0.3 no signal
987 Pneumonitis 17 0.3 0.3 no signal
988 Inappropriate Schedule Of Product Administration 111 0.3 0.3 no signal
989 Multi-organ Failure 11 0.3 0.3 no signal
990 Circumstance Or Information Capable Of Leading To Medication Error 21 0.3 0.3 no signal
991 Pulmonary Oedema 28 0.3 0.3 no signal
992 Intraocular Pressure Increased 8 0.3 0.3 no signal
993 Therapy Change 6 0.3 0.3 no signal
994 Tuberculosis 8 0.3 0.3 no signal
995 Unresponsive To Stimuli 16 0.3 0.3 no signal
996 Neutrophil Count Decreased 25 0.3 0.3 no signal
997 Drug Effective For Unapproved Indication 18 0.3 0.3 no signal
998 Dysgeusia 46 0.3 0.3 no signal
999 Shock 14 0.3 0.3 no signal
1000 Eye Disorder 20 0.3 0.3 no signal
1001 Eye Pruritus 20 0.3 0.3 no signal
1002 Insurance Issue 9 0.3 0.3 no signal
1003 Renal Failure Acute 26 0.3 0.3 no signal
1004 Rheumatoid Arthritis 68 0.3 0.3 no signal
1005 Haemorrhage Intracranial 9 0.3 0.3 no signal
1006 Faeces Discoloured 13 0.3 0.3 no signal
1007 Tachypnoea 8 0.2 0.2 no signal
1008 Hepatic Cirrhosis 11 0.2 0.2 no signal
1009 Helicobacter Infection 6 0.2 0.2 no signal
1010 Accident 7 0.2 0.2 no signal
1011 Chronic Kidney Disease 45 0.2 0.2 no signal
1012 Hypoacusis 25 0.2 0.2 no signal
1013 Pneumonia 187 0.2 0.2 no signal
1014 Renal Disorder 27 0.2 0.2 no signal
1015 Thyroid Cancer 7 0.2 0.2 no signal
1016 Hypomagnesaemia 8 0.2 0.2 no signal
1017 Product Dose Omission Issue 164 0.2 0.2 no signal
1018 Mucosal Inflammation 15 0.2 0.2 no signal
1019 Orthostatic Hypotension 10 0.2 0.2 no signal
1020 White Blood Cell Count Decreased 62 0.2 0.2 no signal
1021 Glaucoma 11 0.2 0.2 no signal
1022 Urinary Retention 19 0.2 0.2 no signal
1023 Wrong Technique In Drug Usage Process 21 0.2 0.2 no signal
1024 Neoplasm Progression 20 0.2 0.2 no signal
1025 Respiratory Disorder 17 0.2 0.2 no signal
1026 Dystonia 11 0.2 0.2 no signal
1027 Blood Potassium Decreased 17 0.2 0.2 no signal
1028 Hepatic Enzyme Increased 38 0.2 0.2 no signal
1029 Sleep Disorder Due To A General Medical Condition 9 0.2 0.2 no signal
1030 Septic Shock 24 0.2 0.2 no signal
1031 Dry Skin 73 0.2 0.2 no signal
1032 Drug-induced Liver Injury 17 0.2 0.2 no signal
1033 Gastrointestinal Pain 6 0.2 0.2 no signal
1034 No Adverse Event 97 0.2 0.2 no signal
1035 Blood Glucose Fluctuation 6 0.2 0.2 no signal
1036 Stomatitis 33 0.2 0.2 no signal
1037 Covid-19 96 0.2 0.2 no signal
1038 Dermatitis Atopic 27 0.2 0.2 no signal
1039 Neuropathy Peripheral 51 0.2 0.2 no signal
1040 Sepsis 60 0.2 0.2 no signal
1041 Liver Injury 13 0.2 0.2 no signal
1042 Erythema Multiforme 5 0.2 0.2 no signal
1043 Colon Cancer 8 0.2 0.2 no signal
1044 Atrial Fibrillation 52 0.2 0.2 no signal
1045 C-reactive Protein Increased 19 0.2 0.2 no signal
1046 Eye Irritation 29 0.2 0.2 no signal
1047 Intentional Drug Misuse 11 0.2 0.2 no signal
1048 Pain Of Skin 14 0.2 0.2 no signal
1049 Uveitis 7 0.2 0.2 no signal
1050 Blood Bilirubin Increased 14 0.2 0.2 no signal
1051 Drug Effect Incomplete 19 0.2 0.2 no signal
1052 Gait Inability 17 0.2 0.2 no signal
1053 Skin Cancer 11 0.2 0.2 no signal
1054 Product Dispensing Error 11 0.2 0.2 no signal
1055 Covid-19 Pneumonia 6 0.2 0.2 no signal
1056 Prescribed Underdose 10 0.2 0.2 no signal
1057 Blood Glucose Increased 94 0.2 0.2 no signal
1058 Rash Maculo-papular 11 0.2 0.2 no signal
1059 Hepatotoxicity 11 0.2 0.2 no signal
1060 Spinal Operation 6 0.2 0.2 no signal
1061 Hypothermia 5 0.2 0.2 no signal
1062 Hyperkalaemia 17 0.2 0.2 no signal
1063 No Therapeutic Response 6 0.2 0.2 no signal
1064 Drug Withdrawal Syndrome 43 0.2 0.2 no signal
1065 Pancytopenia 27 0.2 0.2 no signal
1066 Drug Level Increased 8 0.2 0.2 no signal
1067 Blood Glucose Decreased 23 0.2 0.2 no signal
1068 Hypocalcaemia 9 0.2 0.2 no signal
1069 Full Blood Count Abnormal 5 0.2 0.2 no signal
1070 Metabolic Acidosis 15 0.2 0.2 no signal
1071 Eructation 9 0.2 0.2 no signal
1072 Mydriasis 6 0.2 0.2 no signal
1073 Lower Respiratory Tract Infection 21 0.2 0.2 no signal
1074 Hepatic Failure 14 0.2 0.2 no signal
1075 Ocular Discomfort 5 0.2 0.2 no signal
1076 Product Packaging Quantity Issue 5 0.2 0.2 no signal
1077 Renal Failure 61 0.2 0.2 no signal
1078 Drug Eruption 8 0.2 0.2 no signal
1079 Transaminases Increased 10 0.2 0.2 no signal
1080 Skin Burning Sensation 32 0.2 0.2 no signal
1081 Eye Haemorrhage 6 0.2 0.2 no signal
1082 Adverse Event 41 0.2 0.2 no signal
1083 Fistula 5 0.2 0.2 no signal
1084 Chromaturia 10 0.2 0.2 no signal
1085 Drug Dose Omission 74 0.2 0.2 no signal
1086 Product Complaint 11 0.2 0.2 no signal
1087 Bone Marrow Failure 9 0.2 0.2 no signal
1088 Neoplasm Malignant 29 0.2 0.2 no signal
1089 Product Substitution Issue 25 0.2 0.2 no signal
1090 Skin Exfoliation 36 0.2 0.2 no signal
1091 Product Packaging Issue 4 0.2 0.2 no signal
1092 Hepatic Encephalopathy 4 0.2 0.2 no signal
1093 Unintentional Medical Device Removal 5 0.2 0.2 no signal
1094 Cardio-respiratory Arrest 18 0.2 0.2 no signal
1095 Madarosis 5 0.2 0.2 no signal
1096 Therapy Non-responder 19 0.2 0.2 no signal
1097 Drug Effect Less Than Expected 6 0.2 0.2 no signal
1098 Leukaemia 4 0.2 0.2 no signal
1099 Skin Fissures 8 0.2 0.2 no signal
1100 Febrile Neutropenia 28 0.2 0.2 no signal
1101 Cerebral Haemorrhage 15 0.2 0.2 no signal
1102 Renal Impairment 35 0.2 0.2 no signal
1103 Myelodysplastic Syndrome 6 0.2 0.2 no signal
1104 Anosmia 6 0.2 0.2 no signal
1105 Blood Creatine Phosphokinase Increased 12 0.2 0.2 no signal
1106 Product Dose Omission In Error 11 0.2 0.2 no signal
1107 Thrombocytopenia 45 0.2 0.2 no signal
1108 Malignant Neoplasm Progression 41 0.2 0.2 no signal
1109 Respiratory Failure 29 0.2 0.2 no signal
1110 Hyponatraemia 22 0.2 0.2 no signal
1111 Blood Count Abnormal 6 0.2 0.2 no signal
1112 Product Preparation Error 8 0.2 0.2 no signal
1113 Tardive Dyskinesia 11 0.2 0.2 no signal
1114 Acute Myeloid Leukaemia 6 0.2 0.2 no signal
1115 Product Odour Abnormal 4 0.2 0.2 no signal
1116 Skeletal Injury 4 0.2 0.2 no signal
1117 International Normalised Ratio Increased 11 0.2 0.2 no signal
1118 Agranulocytosis 7 0.2 0.2 no signal
1119 Neutropenia 51 0.2 0.2 no signal
1120 Wrong Technique In Product Usage Process 76 0.2 0.2 no signal
1121 Delirium 13 0.2 0.2 no signal
1122 Premature Delivery 6 0.2 0.2 no signal
1123 Gastrointestinal Haemorrhage 31 0.2 0.2 no signal
1124 Acute Hepatic Failure 5 0.2 0.2 no signal
1125 Therapeutic Response Decreased 22 0.2 0.2 no signal
1126 Application Site Pain 8 0.2 0.2 no signal
1127 Cardiac Arrest 30 0.2 0.2 no signal
1128 Drug Toxicity 5 0.2 0.2 no signal
1129 Ill-defined Disorder 22 0.2 0.2 no signal
1130 Cardiac Failure 29 0.2 0.2 no signal
1131 Red Blood Cell Sedimentation Rate Increased 4 0.2 0.2 no signal
1132 Ageusia 9 0.2 0.2 no signal
1133 Toxicity To Various Agents 60 0.2 0.2 no signal
1134 Hepatic Function Abnormal 13 0.1 0.1 no signal
1135 Internal Haemorrhage 4 0.1 0.1 no signal
1136 Product Prescribing Issue 7 0.1 0.1 no signal
1137 Bradycardia 18 0.1 0.1 no signal
1138 Platelet Count Decreased 36 0.1 0.1 no signal
1139 Psoriasis 44 0.1 0.1 no signal
1140 Neuroleptic Malignant Syndrome 4 0.1 0.1 no signal
1141 Overdose 71 0.1 0.1 no signal
1142 Application Site Irritation 4 0.1 0.1 no signal
1143 Eye Inflammation 3 0.1 0.1 no signal
1144 Therapeutic Product Effect Decreased 14 0.1 0.1 no signal
1145 Intentional Overdose 20 0.1 0.1 no signal
1146 Therapeutic Product Effect Incomplete 22 0.1 0.1 no signal
1147 Ankylosing Spondylitis 4 0.1 0.1 no signal
1148 Application Site Erythema 8 0.1 0.1 no signal
1149 Peritonitis Bacterial 3 0.1 0.1 no signal
1150 Full Blood Count Decreased 6 0.1 0.1 no signal
1151 Completed Suicide 25 0.1 0.1 no signal
1152 Acute Kidney Injury 45 0.1 0.1 no signal
1153 Interstitial Lung Disease 14 0.1 0.1 no signal
1154 Product Adhesion Issue 10 0.1 0.1 no signal
1155 Extrapyramidal Disorder 7 0.1 0.1 no signal
1156 Accidental Underdose 4 0.1 0.1 no signal
1157 Pulmonary Arterial Hypertension 4 0.1 0.1 no signal
1158 Erectile Dysfunction 7 0.1 0.1 no signal
1159 Disease Progression 32 0.1 0.1 no signal
1160 Treatment Failure 20 0.1 0.1 no signal
1161 Hospitalisation 37 0.1 0.1 no signal
1162 Peritonitis 5 0.1 0.1 no signal
1163 Cytomegalovirus Infection 4 0.1 0.1 no signal
1164 Poisoning 3 0.1 0.1 no signal
1165 Foetal Exposure During Pregnancy 19 0.1 0.1 no signal
1166 Product Taste Abnormal 3 0.1 0.1 no signal
1167 Application Site Pruritus 5 0.1 0.1 no signal
1168 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.1 0.1 no signal
1169 Product Dose Omission 14 0.1 0.1 no signal
1170 Extra Dose Administered 8 0.1 0.1 no signal
1171 Drug Abuse 15 0.1 0.1 no signal
1172 Drug Dependence 27 0.1 0.1 no signal
1173 Myelosuppression 5 0.1 0.1 no signal
1174 Death 119 0.1 0.1 no signal
1175 Pancreatic Carcinoma 4 0.1 0.1 no signal
1176 Gynaecomastia 4 0.1 0.1 no signal
1177 Dependence 7 0.1 0.1 no signal
1178 Hepatic Cancer 3 0.1 0.1 no signal
1179 Product Storage Error 9 0.0 0.0 no signal
1180 Renal Cancer 4 0.0 0.0 no signal
1181 Bladder Cancer 3 0.0 0.0 no signal