Drug

Misoprostol

1,051 flagged reaction(s) · 35,236 total co-reports · max PRR 8,545.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Labour Augmentation	8	8,545.8	8,552.9	signal
2	Uterine Tachysystole	104	5,697.2	5,759.1	signal
3	Abortion Induced Incomplete	23	4,094.9	4,104.6	signal
4	Post Abortion Infection	15	3,560.8	3,566.3	signal
5	Abortion Incomplete	1,159	3,517.3	3,995.5	signal
6	Induced Abortion Failed	73	2,689.0	2,709.4	signal
7	Endometritis Bacterial	6	2,563.7	2,565.3	signal
8	Postpartum Stress Disorder	9	1,748.0	1,749.6	signal
9	Induced Abortion Haemorrhage	9	1,281.9	1,283.1	signal
10	Foetal Exposure During Delivery	207	943.0	963.5	signal
11	Foetal Methotrexate Syndrome	20	821.7	823.4	signal
12	Post Abortion Complication	8	743.1	743.7	signal
13	Birth Trauma	16	697.6	698.8	signal
14	Endometritis	157	669.5	680.5	signal
15	Traumatic Delivery	12	657.4	658.2	signal
16	Precipitate Labour	15	628.4	629.3	signal
17	Post Abortion Haemorrhage	30	567.2	569.0	signal
18	Truncus Arteriosus Persistent	41	554.4	556.7	signal
19	Retained Products Of Conception	40	521.1	523.2	signal
20	Vascular Resistance Systemic Increased	10	521.1	521.6	signal
21	Anaphylactoid Syndrome Of Pregnancy	16	427.3	428.0	signal
22	Foetal Heart Rate Decreased	100	411.6	415.9	signal
23	Abnormal Labour	19	372.4	373.1	signal
24	Cervix Enlargement	7	356.1	356.3	signal
25	Uterine Cervical Laceration	11	297.5	297.8	signal
26	Uterine Atony	31	297.0	297.9	signal
27	Labour Pain	11	293.8	294.1	signal
28	Perineal Injury	18	291.3	291.9	signal
29	Microgenia	7	287.6	287.8	signal
30	Oral Fibroma	6	272.7	272.9	signal
31	Uterine Hyperstimulation	11	264.1	264.4	signal
32	Uterine Tenderness	9	259.8	260.1	signal
33	Amniocentesis Abnormal	17	259.4	259.9	signal
34	Moebius Ii Syndrome	7	257.8	258.0	signal
35	Foetal Heart Rate Disorder	19	243.1	243.5	signal
36	Neonatal Respiratory Arrest	14	224.9	225.2	signal
37	Kidney Duplex	22	221.7	222.2	signal
38	Abortion Infected	6	217.3	217.4	signal
39	Congenital Multiplex Arthrogryposis	18	206.8	207.1	signal
40	Retained Placenta Or Membranes	25	197.8	198.3	signal
41	Delayed Fontanelle Closure	8	194.2	194.4	signal
42	Amniotic Band Syndrome	9	190.4	190.6	signal
43	Uterine Hypertonus	22	189.5	190.0	signal
44	Uterine Rupture	112	183.9	186.1	signal
45	Adactyly	12	176.8	177.0	signal
46	Infantile Haemangioma	12	173.2	173.4	signal
47	Congenital Cystic Lung	9	173.2	173.4	signal
48	Conjoined Twins	7	164.3	164.5	signal
49	Abnormal Palmar/plantar Creases	14	162.6	162.8	signal
50	Foetal Heart Rate Increased	6	156.3	156.4	signal
51	Congenital Brain Damage	7	155.8	155.9	signal
52	Meconium In Amniotic Fluid	23	153.1	153.4	signal
53	Micrognathia	33	151.6	152.1	signal
54	Bloody Discharge	73	146.7	147.8	signal
55	Congenital Megaureter	12	142.4	142.6	signal
56	Clinodactyly	17	141.3	141.6	signal
57	External Auditory Canal Atresia	10	140.6	140.7	signal
58	Vitello-intestinal Duct Remnant	7	139.8	139.9	signal
59	Low Set Ears	25	138.4	138.7	signal
60	Congenital Tricuspid Valve Atresia	9	137.3	137.5	signal
61	Neonatal Hypoxia	49	136.5	137.2	signal
62	Brachycephaly	6	136.4	136.5	signal
63	Meningocele	9	130.8	130.9	signal
64	Congenital Nail Disorder	7	130.0	130.1	signal
65	Uterine Hypotonus	7	126.7	126.8	signal
66	Cardiac Septal Defect	38	119.9	120.4	signal
67	Skeletal Dysplasia	7	116.8	116.9	signal
68	Uterine Contractions Abnormal	14	116.4	116.5	signal
69	Labour Induction	7	115.9	116.0	signal
70	Postpartum Haemorrhage	66	114.7	115.5	signal
71	Wrist Deformity	30	110.1	110.5	signal
72	Complication Of Delivery	14	109.6	109.7	signal
73	Anomaly Of External Ear Congenital	15	108.3	108.4	signal
74	Congenital Cardiovascular Anomaly	39	104.2	104.6	signal
75	Hypertelorism Of Orbit	19	101.7	101.9	signal
76	Foetal Heart Rate Abnormal	41	100.3	100.8	signal
77	Haemangioma Congenital	21	99.5	99.7	signal
78	Maternal Exposure During Delivery	42	97.9	98.3	signal
79	Labour Complication	10	95.8	95.9	signal
80	High Arched Palate	7	92.3	92.4	signal
81	Poor Weight Gain Neonatal	8	91.9	92.0	signal
82	Foetal Distress Syndrome	85	90.4	91.2	signal
83	Genitalia External Ambiguous	7	90.1	90.2	signal
84	Congenital Pulmonary Valve Atresia	9	89.9	89.9	signal
85	Meningomyelocele	23	85.3	85.5	signal
86	Retrognathia	12	84.1	84.2	signal
87	Ruptured Ectopic Pregnancy	29	83.6	83.9	signal
88	Congenital Coronary Artery Malformation	6	80.1	80.2	signal
89	Brachydactyly	7	80.0	80.0	signal
90	Antepartum Haemorrhage	15	79.9	80.0	signal
91	Anaemia Of Pregnancy	6	79.1	79.2	signal
92	International Normalised Ratio Fluctuation	73	78.1	78.7	signal
93	Arnold-chiari Malformation	33	77.1	77.3	signal
94	Double Outlet Right Ventricle	10	74.7	74.8	signal
95	Arrested Labour	8	74.6	74.7	signal
96	Limb Reduction Defect	19	73.5	73.7	signal
97	Neonatal Asphyxia	23	72.6	72.8	signal
98	Anencephaly	18	70.6	70.7	signal
99	Respiratory Disorder Neonatal	50	70.2	70.6	signal
100	Skull Malformation	20	68.6	68.7	signal
101	Apparent Life Threatening Event	13	67.6	67.7	signal
102	Congenital Choroid Plexus Cyst	9	65.4	65.5	signal
103	Vulvovaginal Injury	16	64.4	64.5	signal
104	Newborn Persistent Pulmonary Hypertension	8	63.5	63.6	signal
105	Microcephaly	36	63.3	63.5	signal
106	Cerebral Haemorrhage Neonatal	6	62.8	62.9	signal
107	Urinary Bladder Rupture	7	61.5	61.6	signal
108	Congenital Hydrocephalus	14	60.8	60.9	signal
109	Toxic Shock Syndrome	17	59.7	59.8	signal
110	Premature Separation Of Placenta	41	58.8	59.1	signal
111	Congenital Foot Malformation	12	58.3	58.3	signal
112	Congenital Eye Disorder	7	57.5	57.6	signal
113	Foetal Heart Rate Deceleration	6	57.0	57.0	signal
114	Foetal Heart Rate Deceleration Abnormality	18	56.9	57.0	signal
115	Polyhydramnios	26	56.7	56.8	signal
116	Nail Bed Bleeding	14	54.9	55.0	signal
117	Vesicoureteric Reflux	10	54.5	54.6	signal
118	Renal Aplasia	17	53.3	53.4	signal
119	Pulmonary Hypoplasia	19	53.0	53.1	signal
120	Neonatal Seizure	6	52.8	52.8	signal
121	Congenital Hydronephrosis	17	52.5	52.6	signal
122	Cyanosis Neonatal	15	52.4	52.5	signal
123	Pelvic Inflammatory Disease	34	50.3	50.5	signal
124	Lyme Disease	75	50.1	50.4	signal
125	Cerebral Ventricle Dilatation	26	49.7	49.8	signal
126	Pregnancy	449	49.2	51.5	signal
127	Microphthalmos	6	48.2	48.2	signal
128	Pelvic Infection	10	47.5	47.5	signal
129	Gross Motor Delay	6	47.3	47.3	signal
130	Congenital Diaphragmatic Hernia	8	44.9	44.9	signal
131	Congenital Musculoskeletal Anomaly	9	44.6	44.7	signal
132	Tachycardia Foetal	10	44.6	44.6	signal
133	Apgar Score Low	26	44.4	44.5	signal
134	Placental Insufficiency	16	43.8	43.8	signal
135	Uterine Dilation And Curettage	18	43.7	43.8	signal
136	Nose Deformity	7	41.4	41.5	signal
137	Limb Malformation	15	41.2	41.3	signal
138	Small For Dates Baby	92	40.7	41.1	signal
139	Exomphalos	10	40.7	40.7	signal
140	Foetal Death	95	40.4	40.8	signal
141	Bradycardia Foetal	15	40.4	40.5	signal
142	Congenital Cystic Kidney Disease	15	38.7	38.8	signal
143	Congenital Hand Malformation	12	38.4	38.4	signal
144	Haemorrhage In Pregnancy	25	38.3	38.4	signal
145	Uterine Haemorrhage	74	38.3	38.6	signal
146	Heart Disease Congenital	62	38.3	38.5	signal
147	Neonatal Infection	6	38.2	38.2	signal
148	Syndactyly	14	37.2	37.3	signal
149	Ventricular Septal Defect	97	37.1	37.4	signal
150	Gestational Diabetes	79	37.0	37.3	signal
151	Agitation Neonatal	16	37.0	37.0	signal
152	Congenital Nose Malformation	9	36.9	36.9	signal
153	Cerebral Palsy	16	36.8	36.9	signal
154	Complications Of Maternal Exposure To Therapeutic Drugs	11	35.1	35.2	signal
155	Oesophageal Atresia	10	35.1	35.1	signal
156	Spina Bifida	33	34.5	34.6	signal
157	Uterine Cervix Stenosis	8	33.1	33.1	signal
158	Convulsion Neonatal	8	32.9	32.9	signal
159	Craniosynostosis	13	32.8	32.9	signal
160	Induced Labour	9	32.8	32.8	signal
161	Congenital Central Nervous System Anomaly	16	32.6	32.7	signal
162	Stillbirth	72	32.6	32.8	signal
163	Ectopic Pregnancy	44	31.3	31.4	signal
164	Tracheo-oesophageal Fistula	9	30.8	30.8	signal
165	Iron Deficiency	62	30.6	30.8	signal
166	Foetal Growth Retardation	11	30.4	30.5	signal
167	Hyperbilirubinaemia Neonatal	8	30.2	30.2	signal
168	Hypotonia Neonatal	21	30.1	30.2	signal
169	Heart Sounds Abnormal	10	29.3	29.3	signal
170	Neonatal Disorder	21	28.9	29.0	signal
171	Uterine Infection	7	28.9	28.9	signal
172	Menorrhagia	262	28.9	29.6	signal
173	Hellp Syndrome	8	28.4	28.4	signal
174	Pyloric Stenosis	11	28.3	28.4	signal
175	Abortion Induced	120	27.9	28.3	signal
176	Dysmorphism	30	27.6	27.7	signal
177	Dental Restoration Failure	9	27.4	27.4	signal
178	Amniotic Cavity Infection	9	27.3	27.3	signal
179	Xerophthalmia	7	26.4	26.4	signal
180	Haemorrhage	1,260	26.4	30.2	signal
181	Abortion	35	26.1	26.2	signal
182	Temperature Regulation Disorder	26	26.1	26.1	signal
183	Lupus Vulgaris	14	25.8	25.8	signal
184	Talipes	36	25.4	25.5	signal
185	Pneumocystis Jiroveci Pneumonia	25	24.2	24.3	signal
186	Abortion Missed	14	24.1	24.1	signal
187	Selective Eating Disorder	10	24.0	24.1	signal
188	Vaginitis Bacterial	7	23.9	23.9	signal
189	Developmental Hip Dysplasia	9	23.6	23.6	signal
190	Oligohydramnios	36	23.5	23.6	signal
191	Small Intestine Ulcer	7	23.5	23.5	signal
192	Body Tinea	6	23.3	23.3	signal
193	Cleft Lip And Palate	12	23.3	23.3	signal
194	Pulmonary Mycosis	8	22.1	22.2	signal
195	Hypoglycaemia Neonatal	16	21.8	21.9	signal
196	Uterine Spasm	18	21.4	21.5	signal
197	Multiple Congenital Abnormalities	14	21.0	21.1	signal
198	Vaginal Odour	12	20.8	20.9	signal
199	Death Neonatal	13	20.6	20.6	signal
200	Intra-uterine Death	15	20.1	20.2	signal
201	Upper Respiratory Tract Inflammation	11	19.9	20.0	signal
202	Large For Dates Baby	8	19.7	19.7	signal
203	Uterine Pain	9	19.3	19.3	signal
204	Uterine Enlargement	7	19.2	19.2	signal
205	Bradycardia Neonatal	11	19.2	19.2	signal
206	Maternal Exposure Timing Unspecified	31	18.2	18.2	signal
207	Atrial Septal Defect	70	18.2	18.3	signal
208	Cervix Disorder	6	18.1	18.1	signal
209	Post Procedural Discomfort	17	17.9	17.9	signal
210	Idiopathic Thrombocytopenic Purpura	13	17.7	17.7	signal
211	Neonatal Respiratory Distress	7	17.6	17.6	signal
212	Arteriospasm Coronary	31	17.1	17.2	signal
213	Foetal Exposure During Pregnancy	632	17.0	18.1	signal
214	Maternal Drugs Affecting Foetus	60	16.9	17.0	signal
215	Foetal Growth Restriction	45	16.3	16.3	signal
216	Premature Rupture Of Membranes	18	16.2	16.2	signal
217	Placental Disorder	7	16.0	16.1	signal
218	Hypospadias	15	15.8	15.9	signal
219	Uterine Perforation	62	15.8	15.9	signal
220	Muscle Cramp	13	15.7	15.8	signal
221	Low Birth Weight Baby	57	15.6	15.7	signal
222	Cryptorchism	8	15.5	15.5	signal
223	Prinzmetal Angina	7	15.3	15.3	signal
224	Polydactyly	8	15.1	15.1	signal
225	Streptococcal Sepsis	8	14.6	14.6	signal
226	Pre-eclampsia	31	14.3	14.3	signal
227	Red Blood Cell Sedimentation Rate Increased	72	14.1	14.2	signal
228	Uterine Disorder	15	13.9	14.0	signal
229	Patent Ductus Arteriosus	24	13.1	13.1	signal
230	Neonatal Respiratory Distress Syndrome	21	12.9	12.9	signal
231	Bone Marrow Oedema	6	12.6	12.6	signal
232	Lichen Planus	13	12.3	12.3	signal
233	Complication Of Device Insertion	104	12.2	12.3	signal
234	Exposure During Pregnancy	334	11.7	12.1	signal
235	Pneumonia Cytomegaloviral	10	11.3	11.3	signal
236	Caesarean Section	61	11.3	11.4	signal
237	Suspected Off Label Use	9	11.3	11.3	signal
238	Cleft Palate	10	11.2	11.3	signal
239	Joint Instability	7	11.1	11.1	signal
240	Drug Exposure During Pregnancy	176	11.1	11.3	signal
241	Pleuritic Pain	14	11.0	11.0	signal
242	Limb Deformity	8	10.9	10.9	signal
243	Peritoneal Haemorrhage	7	10.8	10.8	signal
244	Intellectual Disability	7	10.7	10.8	signal
245	Beta Haemolytic Streptococcal Infection	6	10.4	10.4	signal
246	Breech Presentation	6	10.4	10.4	signal
247	Hyperthermia Malignant	7	10.3	10.3	signal
248	Maternal Exposure During Pregnancy	410	10.1	10.5	signal
249	Pelvic Pain	84	10.0	10.1	signal
250	Lymphocyte Percentage Decreased	6	9.7	9.7	signal
251	Platelet Count Increased	58	9.7	9.7	signal
252	Secretion Discharge	54	9.5	9.6	signal
253	Premature Baby	131	9.4	9.5	signal
254	Embedded Device	42	9.3	9.3	signal
255	Medical Device Discomfort	13	9.2	9.2	signal
256	Speech Disorder Developmental	12	9.0	9.1	signal
257	Vaginal Haemorrhage	176	9.0	9.1	signal
258	Spinal Deformity	7	9.0	9.0	signal
259	Thrombocytosis	15	8.9	8.9	signal
260	Premature Labour	23	8.8	8.8	signal
261	Blood Albumin Decreased	31	8.5	8.5	signal
262	Drug Ineffective For Unapproved Indication	218	8.5	8.7	signal
263	Blood Pressure Diastolic Abnormal	10	8.5	8.5	signal
264	Normal Newborn	21	8.4	8.4	signal
265	Device Placement Issue	12	8.4	8.4	signal
266	Developmental Delay	35	8.4	8.4	signal
267	Clostridial Infection	13	8.3	8.3	signal
268	Growth Retardation	11	8.1	8.1	signal
269	Medical Device Pain	8	8.0	8.1	signal
270	Tongue Oedema	14	7.9	8.0	signal
271	Hysterectomy	31	7.8	7.8	signal
272	Procedural Haemorrhage	14	7.8	7.8	signal
273	Disseminated Intravascular Coagulation	50	7.7	7.7	signal
274	Metrorrhagia	61	7.7	7.7	signal
275	Hepatitis Fulminant	10	7.3	7.3	signal
276	Acute Pulmonary Oedema	18	7.0	7.0	signal
277	Disseminated Tuberculosis	8	6.8	6.8	signal
278	Haemorrhagic Anaemia	14	6.8	6.8	signal
279	Blood Loss Anaemia	7	6.8	6.8	signal
280	Hyperpyrexia	13	6.8	6.8	signal
281	Autism Spectrum Disorder	17	6.8	6.8	signal
282	Gastric Polyps	7	6.7	6.7	signal
283	Procedural Pain	85	6.7	6.7	signal
284	Hypoxic-ischaemic Encephalopathy	8	6.6	6.6	signal
285	Haemangioma	7	6.6	6.6	signal
286	Muscle Contracture	6	6.4	6.4	signal
287	Intra-abdominal Haemorrhage	7	6.4	6.4	signal
288	Pyelonephritis	25	6.3	6.3	signal
289	Vomiting Projectile	8	6.1	6.1	signal
290	Strabismus	8	5.9	5.9	signal
291	Staphylococcal Infection	89	5.8	5.9	signal
292	Fear Of Death	6	5.8	5.8	signal
293	Anaemia	511	5.8	6.1	signal
294	Anal Fissure	14	5.7	5.7	signal
295	Rales	15	5.6	5.6	signal
296	Circulatory Collapse	44	5.6	5.6	signal
297	Nephrogenic Anaemia	12	5.6	5.6	signal
298	Haemodynamic Instability	19	5.5	5.5	signal
299	Gastric Ulcer Haemorrhage	14	5.4	5.4	signal
300	Genital Haemorrhage	32	5.4	5.4	signal
301	Duodenal Ulcer Perforation	18	5.3	5.3	signal
302	Nystagmus	13	5.3	5.3	signal
303	Gastrointestinal Necrosis	7	5.2	5.2	signal
304	Peptic Ulcer	8	5.2	5.2	signal
305	Blood Lactate Dehydrogenase Increased	38	5.2	5.2	signal
306	Synovitis	43	5.2	5.2	signal
307	Pregnancy With Contraceptive Device	21	5.0	5.1	signal
308	Spinal Column Stenosis	11	5.0	5.0	signal
309	Spinal Osteoarthritis	20	4.9	4.9	signal
310	Shock Haemorrhagic	18	4.8	4.8	signal
311	Abdominal Tenderness	11	4.8	4.8	signal
312	Hypotonia	22	4.8	4.8	signal
313	Vaginal Discharge	22	4.8	4.8	signal
314	Congenital Anomaly	17	4.7	4.7	signal
315	Dyspareunia	10	4.7	4.7	signal
316	Ventricular Hypokinesia	7	4.7	4.7	signal
317	Live Birth	18	4.7	4.7	signal
318	Pain In Jaw	61	4.7	4.7	signal
319	Oxygen Saturation Abnormal	6	4.6	4.6	signal
320	Abdominal Pain Lower	54	4.6	4.6	signal
321	Vaginal Infection	10	4.6	4.6	signal
322	Pulmonary Tuberculosis	9	4.6	4.6	signal
323	Bk Virus Infection	7	4.5	4.5	signal
324	Maternal Exposure Before Pregnancy	14	4.5	4.5	signal
325	Joint Effusion	14	4.4	4.4	signal
326	Bronchopneumonia	7	4.4	4.4	signal
327	Ovarian Cyst	20	4.3	4.3	signal
328	Necrotising Fasciitis	7	4.3	4.3	signal
329	Trigeminal Neuralgia	8	4.3	4.3	signal
330	Epstein-barr Virus Infection	12	4.2	4.2	signal
331	Spondylitis	7	4.2	4.2	signal
332	Gastrointestinal Perforation	8	4.2	4.2	signal
333	Muscle Spasms	352	4.2	4.3	signal
334	Atelectasis	18	4.0	4.0	signal
335	Finger Deformity	9	4.0	4.0	signal
336	Hyperthermia	14	4.0	4.0	signal
337	Attention Deficit/hyperactivity Disorder	6	4.0	4.0	signal
338	Otitis Media	6	3.9	3.9	signal
339	Acute Coronary Syndrome	15	3.9	3.9	signal
340	Exposure During Breast Feeding	6	3.9	3.9	signal
341	Interstitial Lung Disease	86	3.9	3.9	signal
342	Skin Odour Abnormal	7	3.9	3.9	signal
343	Syncope	178	3.9	3.9	signal
344	Trismus	9	3.8	3.8	signal
345	Large Intestine Perforation	12	3.7	3.7	signal
346	Grip Strength Decreased	15	3.7	3.7	signal
347	Urine Output Decreased	15	3.7	3.7	signal
348	Foot Deformity	19	3.7	3.7	signal
349	Premature Delivery	27	3.7	3.7	signal
350	Haemorrhage Subcutaneous	6	3.7	3.7	signal
351	Pleurisy	10	3.6	3.6	signal
352	Helicobacter Infection	17	3.6	3.6	signal
353	Toxic Epidermal Necrolysis	25	3.6	3.6	signal
354	Mass	23	3.6	3.6	signal
355	Abortion Spontaneous	66	3.6	3.6	signal
356	Post-traumatic Stress Disorder	11	3.6	3.6	signal
357	Cholecystitis Chronic	11	3.5	3.5	signal
358	Protein Urine Present	8	3.5	3.5	signal
359	Necrosis	9	3.5	3.5	signal
360	Blood Alkaline Phosphatase Increased	40	3.5	3.5	signal
361	Blood Urea Increased	27	3.5	3.5	signal
362	Pathological Fracture	8	3.4	3.4	signal
363	Duodenal Ulcer	11	3.4	3.4	signal
364	Intermenstrual Bleeding	8	3.4	3.4	signal
365	Blood Pressure Systolic Decreased	7	3.4	3.4	signal
366	Irritable Bowel Syndrome	33	3.3	3.4	signal
367	Impaired Work Ability	33	3.3	3.3	signal
368	Hepatic Function Abnormal	57	3.3	3.3	signal
369	Paraesthesia Oral	22	3.3	3.3	signal
370	Dysmenorrhoea	20	3.3	3.3	signal
371	Obstructive Airways Disorder	17	3.3	3.3	signal
372	C-reactive Protein Increased	55	3.3	3.3	signal
373	Intervertebral Disc Degeneration	14	3.3	3.3	signal
374	Uterine Leiomyoma	11	3.3	3.3	signal
375	Abdominal Pain	348	3.2	3.3	signal
376	Tibia Fracture	7	3.2	3.2	signal
377	Ulcer Haemorrhage	10	3.2	3.2	signal
378	Hydrocephalus	8	3.2	3.2	signal
379	Arthritis Bacterial	6	3.2	3.2	signal
380	Hypovolaemic Shock	7	3.2	3.2	signal
381	Anorexia	19	3.2	3.2	signal
382	Cardiomegaly	18	3.1	3.1	signal
383	Device Deployment Issue	17	3.1	3.1	signal
384	Pelvic Fracture	11	3.1	3.1	signal
385	Abscess Limb	6	3.0	3.1	signal
386	Screaming	9	3.0	3.1	signal
387	Cytomegalovirus Infection Reactivation	6	3.0	3.0	signal
388	Enterocolitis	8	3.0	3.0	signal
389	Hypovolaemia	8	3.0	3.0	signal
390	Chills	159	2.9	3.0	signal
391	Haematocrit Decreased	27	2.9	2.9	signal
392	Contraindicated Product Administered	40	2.9	2.9	signal
393	Drug Intolerance	127	2.9	2.9	signal
394	Exostosis	12	2.8	2.9	signal
395	Pneumonia Bacterial	12	2.8	2.9	signal
396	Anal Abscess	7	2.8	2.8	signal
397	Movement Disorder	42	2.8	2.8	signal
398	Bundle Branch Block Right	6	2.8	2.8	signal
399	Product Use In Unapproved Indication	316	2.8	2.9	signal
400	Pericarditis	21	2.7	2.7	signal
401	Streptococcal Infection	7	2.7	2.7	signal
402	Device Dislocation	54	2.7	2.7	signal
403	Anaphylactic Reaction	68	2.7	2.7	signal
404	Lung Infiltration	11	2.7	2.7	signal
405	Nodule	16	2.7	2.7	signal
406	Asphyxia	10	2.7	2.7	signal
407	Skin Atrophy	7	2.6	2.6	signal
408	Gamma-glutamyltransferase Increased	27	2.6	2.6	signal
409	Carpal Tunnel Syndrome	17	2.6	2.6	signal
410	Hyperventilation	7	2.6	2.6	signal
411	Infection	174	2.6	2.6	signal
412	Rheumatoid Arthritis	136	2.6	2.6	signal
413	Post Procedural Haemorrhage	14	2.6	2.6	signal
414	Spinal Compression Fracture	10	2.6	2.6	signal
415	Breast Tenderness	9	2.6	2.6	signal
416	Complication Of Device Removal	20	2.6	2.6	signal
417	Pyrexia	406	2.5	2.6	signal
418	Anaphylactic Shock	30	2.5	2.5	signal
419	Procedural Complication	9	2.5	2.5	signal
420	Peritonitis	24	2.5	2.5	signal
421	Gastric Ulcer	22	2.5	2.5	signal
422	Malabsorption	6	2.5	2.5	signal
423	Posterior Reversible Encephalopathy Syndrome	11	2.5	2.5	signal
424	Tachycardia	102	2.5	2.5	signal
425	Cyanosis	18	2.5	2.5	signal
426	Shock	26	2.5	2.5	signal
427	Septic Shock	49	2.5	2.5	signal
428	Acute Respiratory Distress Syndrome	20	2.5	2.5	signal
429	Pemphigus	14	2.4	2.4	signal
430	Pleural Effusion	68	2.4	2.4	signal
431	Therapeutic Product Effect Incomplete	78	2.4	2.4	signal
432	Blood Cholesterol Increased	51	2.4	2.4	signal
433	Tendonitis	17	2.4	2.4	signal
434	Oral Disorder	8	2.4	2.4	signal
435	Hyperlipidaemia	13	2.4	2.4	signal
436	Multi-organ Failure	19	2.3	2.3	signal
437	Hepatitis Acute	7	2.3	2.3	signal
438	Hepatic Encephalopathy	10	2.3	2.3	signal
439	Refusal Of Treatment By Patient	7	2.3	2.3	signal
440	Tendon Pain	8	2.3	2.3	signal
441	Off Label Use	916	2.3	2.4	signal
442	Tendon Rupture	13	2.3	2.3	signal
443	Pallor	28	2.2	2.2	signal
444	Pulmonary Haemorrhage	8	2.2	2.2	signal
445	Ecchymosis	7	2.2	2.2	no signal
446	Encephalitis	7	2.2	2.2	no signal
447	Acute Myocardial Infarction	30	2.2	2.2	signal
448	Hepatomegaly	10	2.2	2.2	signal
449	Drug Resistance	26	2.2	2.2	signal
450	Oxygen Saturation Decreased	56	2.2	2.2	signal
451	Myositis	9	2.2	2.2	signal
452	Hypoaesthesia	150	2.2	2.2	signal
453	Aspartate Aminotransferase Increased	53	2.2	2.2	signal
454	Cardiac Arrest	82	2.1	2.2	signal
455	Red Blood Cell Count Decreased	28	2.1	2.1	signal
456	Injury	69	2.1	2.1	signal
457	Osteoarthritis	41	2.1	2.1	signal
458	Night Sweats	31	2.1	2.1	signal
459	Tenderness	10	2.1	2.1	signal
460	Haemoglobin Decreased	98	2.1	2.1	signal
461	Gastritis	25	2.1	2.1	signal
462	Metabolic Acidosis	30	2.1	2.1	signal
463	Ulcer	15	2.0	2.0	signal
464	Acute Respiratory Failure	18	2.0	2.0	signal
465	Osteomyelitis	17	2.0	2.0	signal
466	Depressed Level Of Consciousness	37	2.0	2.0	signal
467	Drug Withdrawal Syndrome Neonatal	14	2.0	2.0	signal
468	White Blood Cell Count Increased	36	2.0	2.0	signal
469	Blood Iron Decreased	11	2.0	2.0	signal
470	Gastrooesophageal Reflux Disease	74	2.0	2.0	no signal
471	Product Complaint	23	2.0	2.0	no signal
472	Adrenal Insufficiency	11	2.0	2.0	no signal
473	Bacterial Infection	17	2.0	2.0	no signal
474	Vomiting	426	2.0	2.0	no signal
475	Pneumocystis Jirovecii Pneumonia	9	2.0	2.0	no signal
476	Cardiovascular Disorder	23	1.9	2.0	no signal
477	Renal Failure Chronic	7	1.9	1.9	no signal
478	Brain Injury	9	1.9	1.9	no signal
479	Ileus	11	1.9	1.9	no signal
480	Electrocardiogram Abnormal	7	1.9	1.9	no signal
481	Post Procedural Complication	17	1.9	1.9	no signal
482	Drug Hypersensitivity	171	1.9	1.9	no signal
483	Body Temperature Increased	18	1.9	1.9	no signal
484	Pain	540	1.9	2.0	no signal
485	Retinal Detachment	8	1.9	1.9	no signal
486	Alanine Aminotransferase Increased	53	1.9	1.9	no signal
487	Impaired Gastric Emptying	11	1.9	1.9	no signal
488	Lower Respiratory Tract Infection	39	1.9	1.9	no signal
489	Erythema Multiforme	8	1.9	1.9	no signal
490	Inflammation	44	1.9	1.9	no signal
491	Escherichia Infection	7	1.9	1.9	no signal
492	Incontinence	9	1.8	1.8	no signal
493	Pneumonia Aspiration	21	1.8	1.8	no signal
494	Cholecystitis	10	1.8	1.8	no signal
495	Dyskinesia	34	1.8	1.8	no signal
496	Altered State Of Consciousness	18	1.8	1.8	no signal
497	Paralysis	12	1.8	1.8	no signal
498	Sepsis	93	1.8	1.8	no signal
499	Diverticulum	6	1.8	1.8	no signal
500	Oedema	45	1.8	1.8	no signal
501	Pulmonary Congestion	11	1.8	1.8	no signal
502	Leukocytosis	15	1.8	1.8	no signal
503	Product Communication Issue	7	1.8	1.8	no signal
504	Hemiparesis	14	1.8	1.8	no signal
505	Scar	14	1.8	1.8	no signal
506	Abscess	13	1.8	1.8	no signal
507	Generalised Oedema	10	1.8	1.8	no signal
508	Malnutrition	9	1.8	1.8	no signal
509	Ventricular Fibrillation	9	1.8	1.8	no signal
510	Immunosuppression	7	1.7	1.7	no signal
511	Gingival Bleeding	11	1.7	1.7	no signal
512	Disease Recurrence	38	1.7	1.7	no signal
513	Dizziness	396	1.7	1.8	no signal
514	Lymphocyte Count Decreased	14	1.7	1.7	no signal
515	Hepatocellular Carcinoma	6	1.7	1.7	no signal
516	Presyncope	19	1.7	1.7	no signal
517	Dysstasia	23	1.7	1.7	no signal
518	Hypoalbuminaemia	6	1.7	1.7	no signal
519	Sleep Apnoea Syndrome	15	1.7	1.7	no signal
520	Respiratory Failure	57	1.7	1.7	no signal
521	Loss Of Consciousness	99	1.7	1.7	no signal
522	Hiatus Hernia	10	1.7	1.7	no signal
523	Hypoxia	27	1.7	1.7	no signal
524	Haematoma	20	1.7	1.7	no signal
525	Splenomegaly	9	1.7	1.7	no signal
526	Liver Disorder	34	1.7	1.7	no signal
527	Face Oedema	13	1.7	1.7	no signal
528	Device Expulsion	50	1.7	1.7	no signal
529	Dysuria	28	1.6	1.6	no signal
530	Increased Tendency To Bruise	7	1.6	1.6	no signal
531	Heavy Menstrual Bleeding	6	1.6	1.6	no signal
532	Feeling Cold	21	1.6	1.6	no signal
533	Device Use Issue	13	1.6	1.6	no signal
534	Ascites	22	1.6	1.6	no signal
535	Hyperkalaemia	26	1.6	1.6	no signal
536	Liver Injury	18	1.6	1.6	no signal
537	Quality Of Life Decreased	10	1.6	1.6	no signal
538	Blood Potassium Increased	12	1.6	1.6	no signal
539	Transient Ischaemic Attack	25	1.6	1.6	no signal
540	Spinal Disorder	7	1.6	1.6	no signal
541	Aphasia	22	1.6	1.6	no signal
542	Device Difficult To Use	48	1.6	1.6	no signal
543	Muscle Spasticity	9	1.6	1.6	no signal
544	Dystonia	14	1.6	1.6	no signal
545	Pulmonary Hypertension	15	1.6	1.6	no signal
546	Glossodynia	16	1.6	1.6	no signal
547	Bronchitis	53	1.5	1.5	no signal
548	Arthritis	56	1.5	1.5	no signal
549	Mitral Valve Incompetence	8	1.5	1.5	no signal
550	Myocarditis	8	1.5	1.5	no signal
551	Sinus Tachycardia	10	1.5	1.5	no signal
552	Swelling	65	1.5	1.5	no signal
553	Electrolyte Imbalance	8	1.5	1.5	no signal
554	Cardiac Murmur	6	1.5	1.5	no signal
555	Wound	19	1.5	1.5	no signal
556	Cold Sweat	12	1.5	1.5	no signal
557	Melaena	15	1.5	1.5	no signal
558	Cellulitis	34	1.5	1.5	no signal
559	Joint Range Of Motion Decreased	9	1.5	1.5	no signal
560	Oropharyngeal Discomfort	6	1.5	1.5	no signal
561	Ataxia	8	1.5	1.5	no signal
562	Thrombosis	54	1.4	1.5	no signal
563	Product Use Issue	125	1.4	1.5	no signal
564	Tachypnoea	9	1.4	1.4	no signal
565	Pancytopenia	37	1.4	1.4	no signal
566	Skin Ulcer	17	1.4	1.4	no signal
567	Sudden Death	7	1.4	1.4	no signal
568	Cerebral Infarction	16	1.4	1.4	no signal
569	Oedema Peripheral	80	1.4	1.4	no signal
570	Type 2 Diabetes Mellitus	22	1.4	1.4	no signal
571	Systemic Lupus Erythematosus	23	1.4	1.4	no signal
572	Therapeutic Response Decreased	39	1.4	1.4	no signal
573	Aspiration	7	1.4	1.4	no signal
574	Tremor	107	1.4	1.4	no signal
575	Herpes Zoster	37	1.4	1.4	no signal
576	Rash Erythematous	30	1.4	1.4	no signal
577	Musculoskeletal Discomfort	11	1.4	1.4	no signal
578	Nephropathy	6	1.4	1.4	no signal
579	Platelet Count Decreased	68	1.4	1.4	no signal
580	Hypocalcaemia	12	1.4	1.4	no signal
581	Head Injury	20	1.4	1.4	no signal
582	Blood Pressure Decreased	42	1.4	1.4	no signal
583	Lung Disorder	31	1.4	1.4	no signal
584	Osteoporosis	26	1.4	1.4	no signal
585	Orthostatic Hypotension	11	1.4	1.4	no signal
586	Hypotension	126	1.4	1.4	no signal
587	Nephropathy Toxic	7	1.4	1.4	no signal
588	Blood Bilirubin Increased	17	1.4	1.4	no signal
589	Hypertension	132	1.3	1.4	no signal
590	Blood Calcium Decreased	7	1.3	1.3	no signal
591	Muscle Tightness	10	1.3	1.3	no signal
592	Parkinsonism	6	1.3	1.3	no signal
593	Diverticulitis	17	1.3	1.3	no signal
594	Back Disorder	10	1.3	1.3	no signal
595	Internal Haemorrhage	7	1.3	1.3	no signal
596	Impaired Healing	20	1.3	1.3	no signal
597	Neck Pain	34	1.3	1.3	no signal
598	Pulmonary Mass	9	1.3	1.3	no signal
599	Renal Failure Acute	26	1.3	1.3	no signal
600	Rash Macular	21	1.3	1.3	no signal
601	Pulmonary Oedema	27	1.3	1.3	no signal
602	Bradycardia	32	1.3	1.3	no signal
603	Osteonecrosis Of Jaw	15	1.3	1.3	no signal
604	Faeces Discoloured	13	1.3	1.3	no signal
605	Unintentional Medical Device Removal	7	1.3	1.3	no signal
606	Haematochezia	33	1.3	1.3	no signal
607	Bone Disorder	11	1.3	1.3	no signal
608	Eyelid Oedema	7	1.3	1.3	no signal
609	Cardiac Failure	48	1.3	1.3	no signal
610	Tooth Abscess	6	1.3	1.3	no signal
611	Chronic Kidney Disease	45	1.3	1.3	no signal
612	Pulmonary Embolism	56	1.3	1.3	no signal
613	Mobility Decreased	42	1.3	1.3	no signal
614	Device Breakage	23	1.3	1.3	no signal
615	Blood Sodium Decreased	11	1.3	1.3	no signal
616	Economic Problem	9	1.3	1.3	no signal
617	Device Related Infection	9	1.3	1.3	no signal
618	Coronary Artery Occlusion	8	1.3	1.3	no signal
619	Oral Pain	13	1.3	1.3	no signal
620	Diplopia	15	1.3	1.3	no signal
621	Weight Fluctuation	6	1.2	1.2	no signal
622	Heart Rate Increased	57	1.2	1.2	no signal
623	Respiratory Arrest	16	1.2	1.2	no signal
624	Lip Swelling	19	1.2	1.2	no signal
625	Transfusion	6	1.2	1.2	no signal
626	Metastases To Liver	10	1.2	1.2	no signal
627	Full Blood Count Abnormal	6	1.2	1.2	no signal
628	Drug Eruption	10	1.2	1.2	no signal
629	Nausea	445	1.2	1.2	no signal
630	Cyst	7	1.2	1.2	no signal
631	Haemorrhoids	11	1.2	1.2	no signal
632	Blood Pressure Systolic Increased	11	1.2	1.2	no signal
633	Jaundice	15	1.2	1.2	no signal
634	Pain Of Skin	15	1.2	1.2	no signal
635	Angina Pectoris	16	1.2	1.2	no signal
636	Contusion	53	1.2	1.2	no signal
637	Drug Interaction	87	1.2	1.2	no signal
638	Musculoskeletal Stiffness	48	1.2	1.2	no signal
639	Intervertebral Disc Protrusion	12	1.2	1.2	no signal
640	Gastric Disorder	19	1.2	1.2	no signal
641	Neutrophil Count Decreased	22	1.2	1.2	no signal
642	Osteonecrosis	18	1.2	1.2	no signal
643	End Stage Renal Disease	10	1.2	1.2	no signal
644	Blood Thyroid Stimulating Hormone Increased	5	1.2	1.2	no signal
645	Cytomegalovirus Infection	9	1.2	1.2	no signal
646	Fungal Infection	18	1.2	1.2	no signal
647	Insurance Issue	8	1.2	1.2	no signal
648	Arthropathy	30	1.2	1.2	no signal
649	Ankylosing Spondylitis	7	1.2	1.2	no signal
650	Incorrect Route Of Product Administration	9	1.2	1.2	no signal
651	Pain In Extremity	158	1.2	1.2	no signal
652	Speech Disorder	28	1.2	1.2	no signal
653	Intestinal Perforation	6	1.2	1.2	no signal
654	Pneumonia	172	1.2	1.2	no signal
655	Asthenia	200	1.2	1.2	no signal
656	Cystitis	17	1.2	1.2	no signal
657	Lactic Acidosis	17	1.1	1.1	no signal
658	Hepatic Failure	16	1.1	1.1	no signal
659	Urinary Tract Infection	90	1.1	1.1	no signal
660	Micturition Urgency	6	1.1	1.1	no signal
661	Impaired Driving Ability	6	1.1	1.1	no signal
662	Incorrect Route Of Drug Administration	19	1.1	1.1	no signal
663	Malaise	230	1.1	1.1	no signal
664	Swelling Face	34	1.1	1.1	no signal
665	Muscle Twitching	12	1.1	1.1	no signal
666	Limb Injury	14	1.1	1.1	no signal
667	Lymphoma	8	1.1	1.1	no signal
668	Ankle Fracture	8	1.1	1.1	no signal
669	Renal Impairment	43	1.1	1.1	no signal
670	Ejection Fraction Decreased	8	1.1	1.1	no signal
671	Condition Aggravated	155	1.1	1.1	no signal
672	Pharyngeal Oedema	8	1.1	1.1	no signal
673	Blood Creatine Phosphokinase Increased	15	1.1	1.1	no signal
674	Dehydration	68	1.1	1.1	no signal
675	Bacteraemia	6	1.1	1.1	no signal
676	Respiratory Distress	14	1.1	1.1	no signal
677	Unresponsive To Stimuli	13	1.1	1.1	no signal
678	Deep Vein Thrombosis	33	1.1	1.1	no signal
679	Pneumothorax	8	1.1	1.1	no signal
680	Mental Status Changes	14	1.1	1.1	no signal
681	Cerebral Haemorrhage	18	1.1	1.1	no signal
682	Myoclonus	6	1.1	1.1	no signal
683	Multiple Organ Dysfunction Syndrome	14	1.1	1.1	no signal
684	Obesity	8	1.1	1.1	no signal
685	Respiratory Disorder	15	1.1	1.1	no signal
686	Bursitis	6	1.1	1.1	no signal
687	Sleep Disorder Due To A General Medical Condition	8	1.1	1.1	no signal
688	Pancreatitis Acute	11	1.1	1.1	no signal
689	Delirium	17	1.1	1.1	no signal
690	Temperature Intolerance	5	1.1	1.1	no signal
691	Subarachnoid Haemorrhage	5	1.1	1.1	no signal
692	Respiratory Depression	6	1.1	1.1	no signal
693	Metastases To Bone	8	1.1	1.1	no signal
694	Cholelithiasis	16	1.1	1.1	no signal
695	Medication Error	27	1.1	1.1	no signal
696	Neutrophil Count Increased	5	1.1	1.1	no signal
697	Myelodysplastic Syndrome	7	1.0	1.0	no signal
698	Femur Fracture	15	1.0	1.0	no signal
699	Convulsion	28	1.0	1.0	no signal
700	Tooth Extraction	6	1.0	1.0	no signal
701	Petechiae	5	1.0	1.0	no signal
702	Gastroenteritis	7	1.0	1.0	no signal
703	Amenorrhoea	8	1.0	1.0	no signal
704	Skin Discolouration	22	1.0	1.0	no signal
705	Abasia	12	1.0	1.0	no signal
706	Hallucination, Visual	10	1.0	1.0	no signal
707	Angioedema	21	1.0	1.0	no signal
708	Dysphagia	45	1.0	1.0	no signal
709	Cardiomyopathy	7	1.0	1.0	no signal
710	Blood Urine Present	9	1.0	1.0	no signal
711	Infusion Related Reaction	31	1.0	1.0	no signal
712	Tuberculosis	6	1.0	1.0	no signal
713	Rotator Cuff Syndrome	6	1.0	1.0	no signal
714	Chest Pain	86	1.0	1.0	no signal
715	Oral Candidiasis	6	1.0	1.0	no signal
716	Leukopenia	23	1.0	1.0	no signal
717	Epilepsy	14	1.0	1.0	no signal
718	Blood Creatinine Increased	30	1.0	1.0	no signal
719	Hand Deformity	6	1.0	1.0	no signal
720	Abdominal Discomfort	76	1.0	1.0	no signal
721	Road Traffic Accident	19	1.0	1.0	no signal
722	Tooth Fracture	5	1.0	1.0	no signal
723	Neuralgia	11	1.0	1.0	no signal
724	Fibromyalgia	11	1.0	1.0	no signal
725	Drug Dispensing Error	7	1.0	1.0	no signal
726	White Blood Cell Count Decreased	49	1.0	1.0	no signal
727	Spinal Fracture	9	1.0	1.0	no signal
728	Emotional Disorder	14	1.0	1.0	no signal
729	Blood Triglycerides Increased	8	1.0	1.0	no signal
730	Stevens-johnson Syndrome	10	1.0	1.0	no signal
731	Nerve Injury	5	1.0	1.0	no signal
732	Back Pain	104	1.0	1.0	no signal
733	Gallbladder Disorder	8	1.0	1.0	no signal
734	Lung Infection	7	1.0	1.0	no signal
735	General Physical Health Deterioration	51	1.0	1.0	no signal
736	Fear	12	1.0	1.0	no signal
737	Bone Marrow Failure	9	1.0	1.0	no signal
738	Restless Legs Syndrome	8	1.0	1.0	no signal
739	Urinary Incontinence	13	1.0	1.0	no signal
740	Dyspepsia	43	0.9	0.9	no signal
741	Haematuria	15	0.9	0.9	no signal
742	Pericardial Effusion	10	0.9	0.9	no signal
743	Hepatitis	11	0.9	0.9	no signal
744	Haemoptysis	12	0.9	0.9	no signal
745	Palpitations	50	0.9	0.9	no signal
746	Tubulointerstitial Nephritis	8	0.9	0.9	no signal
747	Coronary Artery Disease	13	0.9	0.9	no signal
748	Anxiety	121	0.9	0.9	no signal
749	Coagulopathy	7	0.9	0.9	no signal
750	Arrhythmia	20	0.9	0.9	no signal
751	Cardiogenic Shock	6	0.9	0.9	no signal
752	Laceration	4	0.9	0.9	no signal
753	Pulmonary Fibrosis	8	0.9	0.9	no signal
754	Diabetes Mellitus	32	0.9	0.9	no signal
755	Drug Administration Error	13	0.9	0.9	no signal
756	Constipation	90	0.9	0.9	no signal
757	Swollen Tongue	13	0.9	0.9	no signal
758	Hypersensitivity	77	0.9	0.9	no signal
759	Nervous System Disorder	13	0.9	0.9	no signal
760	Upper Gastrointestinal Haemorrhage	7	0.9	0.9	no signal
761	Menstruation Irregular	11	0.9	0.9	no signal
762	Prescribed Overdose	8	0.9	0.9	no signal
763	Hypokinesia	6	0.9	0.9	no signal
764	Thrombocytopenia	46	0.9	0.9	no signal
765	Mental Impairment	10	0.9	0.9	no signal
766	Hepatic Enzyme Increased	28	0.9	0.9	no signal
767	Pulmonary Arterial Hypertension	6	0.9	0.9	no signal
768	Decreased Immune Responsiveness	4	0.9	0.9	no signal
769	Rhabdomyolysis	17	0.9	0.9	no signal
770	Coeliac Disease	4	0.9	0.9	no signal
771	Inflammatory Bowel Disease	4	0.9	0.9	no signal
772	Arthralgia	168	0.9	0.9	no signal
773	Disability	8	0.9	0.9	no signal
774	Paranoia	7	0.9	0.9	no signal
775	Cardio-respiratory Arrest	17	0.9	0.9	no signal
776	Rash	175	0.9	0.9	no signal
777	Libido Decreased	5	0.9	0.9	no signal
778	Throat Irritation	18	0.9	0.9	no signal
779	Paraesthesia	63	0.9	0.9	no signal
780	Chromaturia	9	0.9	0.9	no signal
781	Depression	91	0.9	0.9	no signal
782	Colitis	15	0.9	0.9	no signal
783	Heart Rate Decreased	14	0.9	0.9	no signal
784	Toxic Skin Eruption	4	0.9	0.9	no signal
785	Hyperhidrosis	51	0.9	0.9	no signal
786	Nephrolithiasis	18	0.9	0.9	no signal
787	Haematemesis	10	0.9	0.9	no signal
788	Rib Fracture	8	0.8	0.8	no signal
789	Thyroid Disorder	6	0.8	0.8	no signal
790	Pruritus	147	0.8	0.8	no signal
791	Diarrhoea	250	0.8	0.8	no signal
792	Blood Pressure Increased	59	0.8	0.8	no signal
793	Renal Failure	51	0.8	0.8	no signal
794	Joint Stiffness	10	0.8	0.8	no signal
795	Conjunctivitis	7	0.8	0.8	no signal
796	Product Prescribing Error	9	0.8	0.8	no signal
797	Pharmaceutical Product Complaint	10	0.8	0.8	no signal
798	Disorientation	15	0.8	0.8	no signal
799	Photophobia	7	0.8	0.8	no signal
800	Abdominal Pain Upper	77	0.8	0.8	no signal
801	Asthma	42	0.8	0.8	no signal
802	Joint Swelling	45	0.8	0.8	no signal
803	Dyspnoea Exertional	14	0.8	0.8	no signal
804	Psoriatic Arthropathy	15	0.8	0.8	no signal
805	Increased Appetite	7	0.8	0.8	no signal
806	Rectal Haemorrhage	16	0.8	0.8	no signal
807	Flatulence	21	0.8	0.8	no signal
808	Hypoglycaemia	18	0.8	0.8	no signal
809	Fatigue	288	0.8	0.8	no signal
810	Throat Tightness	10	0.8	0.8	no signal
811	Gait Disturbance	71	0.8	0.8	no signal
812	Fracture	7	0.8	0.8	no signal
813	Dyspnoea	209	0.8	0.8	no signal
814	Gastrointestinal Haemorrhage	31	0.8	0.8	no signal
815	Upper Respiratory Tract Infection	17	0.8	0.8	no signal
816	Insomnia	98	0.8	0.8	no signal
817	Device Issue	32	0.8	0.8	no signal
818	Generalised Tonic-clonic Seizure	6	0.8	0.8	no signal
819	Pulmonary Thrombosis	4	0.8	0.8	no signal
820	Eye Disorder	12	0.8	0.8	no signal
821	Hernia	7	0.8	0.8	no signal
822	Malignant Neoplasm Progression	37	0.8	0.8	no signal
823	Chest Discomfort	37	0.8	0.8	no signal
824	Drug Toxicity	5	0.8	0.8	no signal
825	Ear Pain	7	0.8	0.8	no signal
826	Musculoskeletal Pain	19	0.8	0.8	no signal
827	Visual Acuity Reduced	12	0.8	0.8	no signal
828	Tooth Disorder	8	0.8	0.8	no signal
829	Rash Papular	8	0.8	0.8	no signal
830	Abdominal Distension	37	0.8	0.8	no signal
831	Alopecia	70	0.8	0.8	no signal
832	Fall	118	0.8	0.8	no signal
833	Hypophagia	9	0.8	0.8	no signal
834	Restlessness	13	0.8	0.8	no signal
835	Treatment Failure	29	0.8	0.8	no signal
836	Psoriasis	46	0.8	0.8	no signal
837	Eye Swelling	13	0.8	0.8	no signal
838	Gastric Cancer	9	0.8	0.8	no signal
839	Gastrointestinal Disorder	31	0.8	0.8	no signal
840	Hypokalaemia	16	0.8	0.8	no signal
841	Activities Of Daily Living Impaired	7	0.8	0.8	no signal
842	Respiratory Tract Infection	9	0.8	0.8	no signal
843	Discomfort	21	0.8	0.7	no signal
844	Muscular Weakness	39	0.7	0.7	no signal
845	Urticaria	57	0.7	0.7	no signal
846	Liver Function Test Abnormal	10	0.7	0.7	no signal
847	Anhedonia	9	0.7	0.7	no signal
848	Fluid Overload	5	0.7	0.7	no signal
849	Lymphadenopathy	12	0.7	0.7	no signal
850	Therapy Non-responder	15	0.7	0.7	no signal
851	Knee Arthroplasty	7	0.7	0.7	no signal
852	Ischaemic Stroke	6	0.7	0.7	no signal
853	Muscle Rigidity	4	0.7	0.7	no signal
854	Multiple Sclerosis	16	0.7	0.7	no signal
855	Mouth Ulceration	7	0.7	0.7	no signal
856	Hot Flush	25	0.7	0.7	no signal
857	Drug Ineffective	436	0.7	0.7	no signal
858	Seizure	38	0.7	0.7	no signal
859	Sinusitis	34	0.7	0.7	no signal
860	Urinary Retention	11	0.7	0.7	no signal
861	Hyperglycaemia	12	0.7	0.7	no signal
862	Emotional Distress	40	0.7	0.7	no signal
863	Surgery	19	0.7	0.7	no signal
864	Headache	205	0.7	0.7	no signal
865	Joint Injury	7	0.7	0.7	no signal
866	Extra Dose Administered	13	0.7	0.7	no signal
867	Nasopharyngitis	60	0.7	0.7	no signal
868	Drug-induced Liver Injury	10	0.7	0.7	no signal
869	Blood Glucose Abnormal	6	0.7	0.7	no signal
870	Pancreatitis	17	0.7	0.7	no signal
871	Mental Disorder	14	0.7	0.7	no signal
872	Grand Mal Convulsion	3	0.7	0.7	no signal
873	Eye Inflammation	3	0.7	0.7	no signal
874	Hair Colour Changes	4	0.7	0.7	no signal
875	Atrial Fibrillation	31	0.7	0.7	no signal
876	Neutropenia	43	0.7	0.7	no signal
877	Migraine	30	0.7	0.7	no signal
878	Influenza Like Illness	26	0.7	0.7	no signal
879	Cough	88	0.7	0.7	no signal
880	Neoplasm Progression	11	0.7	0.7	no signal
881	Affect Lability	3	0.7	0.7	no signal
882	Feeling Hot	19	0.7	0.7	no signal
883	Knee Operation	3	0.7	0.7	no signal
884	Cardiac Failure Congestive	25	0.7	0.7	no signal
885	Drug Effective For Unapproved Indication	9	0.7	0.7	no signal
886	Deafness	8	0.7	0.7	no signal
887	Weight Decreased	85	0.7	0.7	no signal
888	Tinnitus	14	0.7	0.7	no signal
889	Complication Associated With Device	4	0.7	0.7	no signal
890	Decreased Appetite	70	0.7	0.7	no signal
891	Crying	11	0.7	0.7	no signal
892	Feeding Disorder	6	0.7	0.7	no signal
893	Agitation	22	0.6	0.6	no signal
894	Somnolence	60	0.6	0.6	no signal
895	Product Prescribing Issue	6	0.6	0.6	no signal
896	Intestinal Obstruction	11	0.6	0.6	no signal
897	Poor Quality Product Administered	3	0.6	0.6	no signal
898	Drug Level Decreased	3	0.6	0.6	no signal
899	Erythema	60	0.6	0.6	no signal
900	Inappropriate Schedule Of Drug Administration	21	0.6	0.6	no signal
901	Dysphonia	17	0.6	0.6	no signal
902	Nasal Congestion	17	0.6	0.6	no signal
903	Product Odour Abnormal	3	0.6	0.6	no signal
904	Pollakiuria	12	0.6	0.6	no signal
905	Intentional Product Misuse	25	0.6	0.6	no signal
906	Unintended Pregnancy	3	0.6	0.6	no signal
907	Sleep Disorder	20	0.6	0.6	no signal
908	Encephalopathy	7	0.6	0.6	no signal
909	Hereditary Angioedema	3	0.6	0.6	no signal
910	Intentional Drug Misuse	6	0.6	0.6	no signal
911	Hypothyroidism	9	0.6	0.6	no signal
912	Acute Kidney Injury	43	0.6	0.6	no signal
913	Mood Swings	9	0.6	0.6	no signal
914	Breast Pain	3	0.6	0.6	no signal
915	Oropharyngeal Pain	26	0.6	0.6	no signal
916	Hypersomnia	8	0.6	0.6	no signal
917	Vertigo	17	0.6	0.6	no signal
918	Eczema	14	0.6	0.6	no signal
919	Balance Disorder	24	0.6	0.6	no signal
920	Cardiac Disorder	26	0.6	0.6	no signal
921	Accidental Overdose	10	0.6	0.6	no signal
922	Bone Pain	16	0.6	0.6	no signal
923	Wrong Technique In Drug Usage Process	10	0.6	0.6	no signal
924	Mucosal Inflammation	7	0.6	0.6	no signal
925	Rash Generalised	7	0.6	0.6	no signal
926	Renal Injury	8	0.6	0.6	no signal
927	Fistula	3	0.6	0.6	no signal
928	Unevaluable Event	20	0.6	0.6	no signal
929	Stomatitis	16	0.6	0.6	no signal
930	Ear Infection	7	0.6	0.6	no signal
931	Skin Lesion	7	0.6	0.6	no signal
932	Palmar-plantar Erythrodysaesthesia Syndrome	6	0.6	0.6	no signal
933	Madarosis	3	0.6	0.6	no signal
934	Productive Cough	12	0.5	0.5	no signal
935	Epistaxis	19	0.5	0.5	no signal
936	Weight Increased	56	0.5	0.5	no signal
937	Diabetic Ketoacidosis	6	0.5	0.5	no signal
938	Overdose	54	0.5	0.5	no signal
939	Hyponatraemia	14	0.5	0.5	no signal
940	Peripheral Swelling	38	0.5	0.5	no signal
941	Panic Attack	9	0.5	0.5	no signal
942	Colitis Ulcerative	11	0.5	0.5	no signal
943	Incorrect Product Administration Duration	5	0.5	0.5	no signal
944	Myocardial Infarction	43	0.5	0.5	no signal
945	Therapeutic Response Unexpected	11	0.5	0.5	no signal
946	Neuropathy Peripheral	23	0.5	0.5	no signal
947	Viral Infection	8	0.5	0.5	no signal
948	Disturbance In Attention	13	0.5	0.5	no signal
949	Feeling Abnormal	57	0.5	0.5	no signal
950	Cataract	14	0.5	0.5	no signal
951	Visual Impairment	29	0.5	0.5	no signal
952	Dry Skin	31	0.5	0.5	no signal
953	Device Use Error	8	0.5	0.5	no signal
954	Blood Potassium Decreased	7	0.5	0.5	no signal
955	Memory Impairment	32	0.5	0.5	no signal
956	Injection Site Induration	3	0.5	0.5	no signal
957	Coma	11	0.5	0.5	no signal
958	Amnesia	15	0.5	0.5	no signal
959	Suicidal Ideation	21	0.5	0.5	no signal
960	Intentional Product Use Issue	20	0.5	0.5	no signal
961	Vision Blurred	31	0.5	0.5	no signal
962	Flushing	23	0.5	0.5	no signal
963	Sopor	3	0.5	0.5	no signal
964	Cerebrovascular Accident	38	0.5	0.5	no signal
965	Incorrect Dose Administered	50	0.5	0.5	no signal
966	Hair Texture Abnormal	3	0.5	0.5	no signal
967	Dry Mouth	18	0.5	0.5	no signal
968	Treatment Noncompliance	12	0.5	0.5	no signal
969	Mood Altered	6	0.5	0.5	no signal
970	Akathisia	3	0.5	0.5	no signal
971	Wheezing	13	0.5	0.5	no signal
972	Hip Fracture	7	0.5	0.5	no signal
973	Drug Effect Incomplete	8	0.5	0.5	no signal
974	Abnormal Dreams	6	0.5	0.5	no signal
975	Influenza	24	0.5	0.5	no signal
976	Ocular Hyperaemia	10	0.5	0.5	no signal
977	Dysarthria	8	0.5	0.5	no signal
978	Disease Progression	25	0.5	0.5	no signal
979	Myalgia	36	0.5	0.5	no signal
980	Confusional State	34	0.5	0.5	no signal
981	Lethargy	12	0.5	0.5	no signal
982	Stress	15	0.5	0.5	no signal
983	Pancreatic Carcinoma	6	0.4	0.4	no signal
984	Multiple Sclerosis Relapse	14	0.4	0.4	no signal
985	Rhinorrhoea	13	0.4	0.4	no signal
986	Drug Effect Decreased	11	0.4	0.4	no signal
987	Hallucination	15	0.4	0.4	no signal
988	Extrapyramidal Disorder	5	0.4	0.4	no signal
989	Inappropriate Schedule Of Product Administration	35	0.4	0.4	no signal
990	Bone Loss	3	0.4	0.4	no signal
991	Ill-defined Disorder	12	0.4	0.4	no signal
992	Eye Irritation	11	0.4	0.4	no signal
993	Fluid Retention	10	0.4	0.4	no signal
994	Electrocardiogram Qt Prolonged	7	0.4	0.4	no signal
995	Limb Discomfort	6	0.4	0.4	no signal
996	Lung Neoplasm Malignant	8	0.4	0.4	no signal
997	Cognitive Disorder	9	0.4	0.4	no signal
998	Renal Disorder	9	0.4	0.4	no signal
999	Chronic Obstructive Pulmonary Disease	10	0.4	0.4	no signal
1000	Nervousness	10	0.4	0.4	no signal
1001	Therapeutic Response Shortened	6	0.4	0.4	no signal
1002	Dry Eye	9	0.4	0.4	no signal
1003	Rash Pruritic	10	0.4	0.4	no signal
1004	Irritability	11	0.4	0.4	no signal
1005	Gait Inability	6	0.4	0.4	no signal
1006	Anger	6	0.4	0.4	no signal
1007	Myelosuppression	6	0.4	0.4	no signal
1008	Febrile Neutropenia	11	0.4	0.4	no signal
1009	Blood Glucose Decreased	8	0.4	0.4	no signal
1010	Hypoacusis	7	0.4	0.4	no signal
1011	Toxicity To Various Agents	27	0.3	0.3	no signal
1012	Aggression	8	0.3	0.3	no signal
1013	Illness	16	0.3	0.3	no signal
1014	Therapeutic Product Effect Decreased	7	0.3	0.3	no signal
1015	Product Quality Issue	21	0.3	0.3	no signal
1016	Completed Suicide	13	0.3	0.3	no signal
1017	Drug Prescribing Error	3	0.3	0.3	no signal
1018	Injection Site Bruising	12	0.3	0.3	no signal
1019	Depressed Mood	8	0.3	0.3	no signal
1020	Neoplasm Malignant	10	0.3	0.3	no signal
1021	Eye Pain	8	0.3	0.3	no signal
1022	Blister	8	0.3	0.3	no signal
1023	Burning Sensation	10	0.3	0.3	no signal
1024	Product Dose Omission	9	0.3	0.3	no signal
1025	Covid-19	24	0.3	0.3	no signal
1026	Injection Site Rash	4	0.3	0.3	no signal
1027	Drug Withdrawal Syndrome	11	0.3	0.3	no signal
1028	Death	104	0.3	0.3	no signal
1029	Dysgeusia	9	0.3	0.3	no signal
1030	Dermatitis Atopic	6	0.3	0.3	no signal
1031	Product Dose Omission Issue	34	0.3	0.3	no signal
1032	Injection Site Swelling	9	0.3	0.3	no signal
1033	Blood Glucose Increased	22	0.3	0.3	no signal
1034	Drug Dose Omission	19	0.2	0.2	no signal
1035	Underdose	8	0.2	0.2	no signal
1036	Tardive Dyskinesia	3	0.2	0.2	no signal
1037	Injection Site Pruritus	7	0.2	0.2	no signal
1038	Adverse Drug Reaction	9	0.2	0.2	no signal
1039	Hospitalisation	15	0.2	0.2	no signal
1040	No Adverse Event	17	0.2	0.2	no signal
1041	Breast Cancer	9	0.2	0.2	no signal
1042	Intentional Overdose	6	0.2	0.2	no signal
1043	Injection Site Pain	28	0.2	0.2	no signal
1044	Acne	7	0.2	0.2	no signal
1045	Accidental Exposure To Product	9	0.2	0.2	no signal
1046	Injection Site Haemorrhage	7	0.2	0.2	no signal
1047	Injection Site Erythema	10	0.2	0.2	no signal
1048	Adverse Event	7	0.2	0.2	no signal
1049	Prostate Cancer	6	0.2	0.2	no signal
1050	Wrong Technique In Product Usage Process	14	0.2	0.1	no signal
1051	Drug Dependence	11	0.1	0.1	no signal