Drug

Naltrexone Hydrochloride

79 flagged reaction(s) · 1,434 total co-reports · max PRR 62.8

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Hyperlipidaemia	53	62.8	65.0	signal
2	Impaired Quality Of Life	62	61.1	63.8	signal
3	Poor Quality Sleep	71	47.0	49.3	signal
4	Impaired Work Ability	60	39.6	41.3	signal
5	Oral Herpes	53	38.6	40.0	signal
6	Skin Disorder	55	23.4	24.3	signal
7	Bone Density Decreased	50	22.3	23.1	signal
8	Serotonin Syndrome	26	19.2	19.6	signal
9	Insurance Issue	17	16.2	16.4	signal
10	Cellulitis	57	16.0	16.6	signal
11	Herpes Zoster	60	14.7	15.3	signal
12	Infusion Site Pain	13	14.4	14.5	signal
13	Cataract	58	13.8	14.4	signal
14	Blood Triglycerides Increased	16	12.8	12.9	signal
15	Joint Range Of Motion Decreased	12	12.7	12.8	signal
16	Dermatitis Contact	10	12.5	12.5	signal
17	Thinking Abnormal	16	12.1	12.2	signal
18	Musculoskeletal Chest Pain	13	11.9	12.0	signal
19	Inflammatory Bowel Disease	8	11.5	11.6	signal
20	Viral Infection	26	11.1	11.2	signal
21	Blood Glucose Abnormal	13	9.9	10.0	signal
22	Scratch	7	9.6	9.6	signal
23	Head Injury	21	9.4	9.5	signal
24	Contusion	62	9.1	9.5	signal
25	Seasonal Allergy	9	9.0	9.1	signal
26	Skin Infection	7	8.9	8.9	signal
27	Gastroenteritis Viral	11	8.6	8.6	signal
28	Initial Insomnia	6	8.3	8.3	signal
29	Bursitis	7	8.2	8.2	signal
30	Panic Attack	21	8.1	8.2	signal
31	Rhabdomyolysis	23	7.8	7.9	signal
32	Blood Pressure Systolic Increased	10	7.2	7.3	signal
33	Drug Effect Less Than Expected	7	7.0	7.0	signal
34	Pancreatitis Acute	11	7.0	7.0	signal
35	Middle Insomnia	9	6.8	6.9	signal
36	Illness	47	6.6	6.8	signal
37	Pharyngitis Streptococcal	5	6.5	6.5	signal
38	Injection Site Mass	17	6.5	6.6	signal
39	Frequent Bowel Movements	12	6.3	6.3	signal
40	Pallor	12	6.2	6.3	signal
41	Hallucination, Auditory	7	6.2	6.2	signal
42	Contraindicated Product Administered	13	6.1	6.1	signal
43	Withdrawal Syndrome	18	6.0	6.1	signal
44	Hepatic Cytolysis	5	5.8	5.8	signal
45	Drug Reaction With Eosinophilia And Systemic Symptoms	10	5.5	5.6	signal
46	Hereditary Angioedema	4	5.4	5.4	signal
47	Product Prescribing Error	9	5.4	5.4	signal
48	Coma	18	5.3	5.4	signal
49	Eye Pruritus	12	5.1	5.2	signal
50	Intentional Self-injury	7	4.9	4.9	signal
51	Pregnancy	7	4.9	4.9	signal
52	Suicidal Ideation	31	4.8	4.9	signal
53	Colitis Ulcerative	15	4.8	4.8	signal
54	Abnormal Behaviour	13	4.6	4.6	signal
55	Psychotic Disorder	9	4.3	4.3	signal
56	Complication Associated With Device	4	4.3	4.3	signal
57	Ovarian Cyst	3	4.2	4.2	signal
58	Euphoric Mood	3	4.1	4.1	signal
59	Hepatocellular Injury	4	4.0	4.0	signal
60	Completed Suicide	23	3.9	3.9	signal
61	Injection Site Nodule	3	3.9	3.9	no signal
62	Sedation	7	3.8	3.8	signal
63	Product Preparation Error	5	3.4	3.4	signal
64	Abasia	6	3.4	3.4	signal
65	Suicide Attempt	14	3.3	3.3	signal
66	Drug Toxicity	3	3.1	3.1	no signal
67	Dermatitis Atopic	10	2.8	2.8	signal
68	Multiple Sclerosis Relapse	13	2.7	2.7	signal
69	Drug Abuse	14	2.4	2.4	signal
70	Therapeutic Response Shortened	5	2.2	2.2	no signal
71	Drug Withdrawal Syndrome	13	2.1	2.1	signal
72	Injection Site Warmth	3	2.1	2.1	no signal
73	Multiple Sclerosis	7	2.1	2.1	no signal
74	Tardive Dyskinesia	4	2.0	2.0	no signal
75	Intentional Overdose	8	1.8	1.8	no signal
76	Injection Site Pain	35	1.6	1.6	no signal
77	Breast Cancer Female	3	1.6	1.6	no signal
78	Wrong Technique In Device Usage Process	4	1.2	1.2	no signal
79	Drug Dependence	9	0.8	0.8	no signal