OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Nicardipine

196 flagged reaction(s) · 6,018 total co-reports · max PRR 33.1
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Premature Baby 205 33.1 34.7 signal
2 Premature Delivery 108 32.9 33.7 signal
3 Posterior Reversible Encephalopathy Syndrome 59 30.2 30.6 signal
4 Hepatic Cytolysis 74 29.5 30.0 signal
5 Eosinophilia 66 18.3 18.6 signal
6 Rash Maculo-papular 74 16.2 16.5 signal
7 Caesarean Section 38 15.7 15.8 signal
8 Hypertensive Crisis 33 14.3 14.4 signal
9 Thrombotic Microangiopathy 28 14.0 14.1 signal
10 Subarachnoid Haemorrhage 28 13.3 13.4 signal
11 Cerebral Infarction 59 11.7 11.8 signal
12 Foetal Exposure During Pregnancy 195 11.6 12.1 signal
13 Pneumonia Aspiration 58 11.3 11.4 signal
14 Hyperkalaemia 76 10.6 10.7 signal
15 Poisoning Deliberate 20 10.4 10.5 signal
16 Maternal Exposure During Pregnancy 183 10.1 10.5 signal
17 Cerebral Haemorrhage 74 10.0 10.2 signal
18 Cholestasis 39 9.9 10.0 signal
19 Toxic Skin Eruption 19 9.1 9.1 signal
20 Acute Respiratory Distress Syndrome 31 8.5 8.5 signal
21 Drug Reaction With Eosinophilia And Systemic Symptoms 44 8.3 8.4 signal
22 Hyponatraemia 96 8.3 8.4 signal
23 Hepatocellular Injury 24 8.2 8.2 signal
24 Exposure During Pregnancy 103 8.0 8.2 signal
25 Respiratory Distress 45 7.9 8.0 signal
26 Hypoxia 57 7.9 8.0 signal
27 Bradycardia 86 7.8 8.0 signal
28 Acute Kidney Injury 243 7.7 8.1 signal
29 Toxic Epidermal Necrolysis 24 7.7 7.7 signal
30 Circulatory Collapse 27 7.6 7.7 signal
31 Drug Exposure During Pregnancy 53 7.4 7.5 signal
32 Brain Oedema 19 7.3 7.3 signal
33 Shock 34 7.2 7.3 signal
34 Petechiae 15 7.0 7.0 signal
35 Haemorrhage Intracranial 21 6.8 6.8 signal
36 Drug Level Increased 23 6.7 6.8 signal
37 Hypokalaemia 63 6.7 6.7 signal
38 Neutrophil Count Increased 14 6.6 6.6 signal
39 Cardiogenic Shock 19 6.5 6.5 signal
40 Multiple Organ Dysfunction Syndrome 37 6.4 6.5 signal
41 Haematoma 34 6.3 6.4 signal
42 Altered State Of Consciousness 28 6.3 6.3 signal
43 Ischaemic Stroke 23 6.2 6.3 signal
44 Hepatic Function Abnormal 47 6.1 6.2 signal
45 Metabolic Acidosis 40 6.1 6.2 signal
46 Pneumothorax 20 6.1 6.1 signal
47 Multi-organ Failure 22 6.1 6.1 signal
48 Proteinuria 23 5.9 5.9 signal
49 Sudden Death 13 5.9 5.9 signal
50 Hypotonia 12 5.8 5.8 signal
51 Gamma-glutamyltransferase Increased 26 5.7 5.7 signal
52 Cardiac Arrest 97 5.7 5.8 signal
53 Orthostatic Hypotension 20 5.6 5.6 signal
54 Encephalopathy 28 5.5 5.6 signal
55 Disseminated Intravascular Coagulation 16 5.5 5.5 signal
56 Anaphylactic Shock 29 5.5 5.5 signal
57 Blood Urea Increased 19 5.5 5.5 signal
58 Renal Tubular Necrosis 11 5.4 5.4 signal
59 Ventricular Tachycardia 18 5.3 5.3 signal
60 Agranulocytosis 20 5.2 5.3 signal
61 Hyperglycaemia 39 5.2 5.2 signal
62 Abortion Induced 10 5.1 5.1 signal
63 Status Epilepticus 12 5.1 5.1 signal
64 Mitral Valve Incompetence 12 5.1 5.1 signal
65 Drug Interaction 167 5.1 5.3 signal
66 Rhabdomyolysis 43 5.0 5.0 signal
67 Sinus Bradycardia 10 5.0 5.0 signal
68 End Stage Renal Disease 19 5.0 5.0 signal
69 Lactic Acidosis 33 5.0 5.0 signal
70 Lymphocyte Count Decreased 18 4.9 4.9 signal
71 Respiratory Failure 73 4.8 4.9 signal
72 Angioedema 44 4.8 4.9 signal
73 Pancreatitis Acute 22 4.8 4.8 signal
74 Subdural Haematoma 14 4.7 4.7 signal
75 Blood Pressure Decreased 64 4.7 4.7 signal
76 Pulmonary Oedema 43 4.6 4.7 signal
77 Product Administration Error 19 4.6 4.6 signal
78 Drug Eruption 16 4.4 4.4 signal
79 Cytomegalovirus Infection 15 4.4 4.4 signal
80 Hypocalcaemia 17 4.4 4.4 signal
81 Pneumocystis Jirovecii Pneumonia 9 4.4 4.4 signal
82 Malnutrition 10 4.4 4.4 signal
83 Generalised Oedema 11 4.3 4.3 signal
84 Acute Respiratory Failure 17 4.3 4.3 signal
85 Depressed Level Of Consciousness 35 4.3 4.3 signal
86 Epilepsy 27 4.3 4.3 signal
87 Rebound Effect 10 4.3 4.3 signal
88 Septic Shock 38 4.3 4.3 signal
89 Blood Lactate Dehydrogenase Increased 14 4.3 4.3 signal
90 Hyperbilirubinaemia 9 4.2 4.2 signal
91 Urosepsis 8 4.2 4.2 signal
92 Bacterial Infection 16 4.2 4.2 signal
93 Hypotension 172 4.2 4.3 signal
94 Tubulointerstitial Nephritis 16 4.1 4.1 signal
95 Bacteraemia 10 4.1 4.1 signal
96 Adrenal Insufficiency 10 4.0 4.1 signal
97 Acute Myeloid Leukaemia 13 4.0 4.1 signal
98 Pancytopenia 46 4.0 4.0 signal
99 Hepatitis 21 4.0 4.0 signal
100 Renal Impairment 66 3.8 3.9 signal
101 Hypothermia 8 3.8 3.8 signal
102 Cytokine Release Syndrome 15 3.8 3.8 signal
103 Inappropriate Antidiuretic Hormone Secretion 8 3.8 3.8 signal
104 Drug Level Decreased 8 3.8 3.8 signal
105 Pericardial Effusion 18 3.8 3.8 signal
106 Hypertension 165 3.8 3.9 signal
107 Renal Failure 103 3.7 3.8 signal
108 Iron Deficiency Anaemia 7 3.7 3.7 signal
109 Aphasia 23 3.7 3.7 signal
110 Aspartate Aminotransferase Increased 40 3.6 3.7 signal
111 Urinary Retention 25 3.6 3.7 signal
112 Blood Creatinine Increased 49 3.6 3.7 signal
113 Renal Failure Acute 32 3.6 3.6 signal
114 Pregnancy 15 3.6 3.6 signal
115 Lung Disorder 36 3.6 3.6 signal
116 Post Procedural Complication 14 3.5 3.5 signal
117 Pleural Effusion 44 3.5 3.5 signal
118 Nephropathy Toxic 8 3.5 3.5 signal
119 Coma 34 3.5 3.5 signal
120 Alanine Aminotransferase Increased 43 3.4 3.4 signal
121 Delirium 24 3.4 3.4 signal
122 Motor Dysfunction 7 3.3 3.4 signal
123 Pulmonary Congestion 9 3.3 3.3 signal
124 Stevens-johnson Syndrome 15 3.3 3.3 signal
125 Neuroleptic Malignant Syndrome 8 3.3 3.3 signal
126 Jaundice 18 3.2 3.2 signal
127 Cardio-respiratory Arrest 28 3.2 3.2 signal
128 Blood Pressure Systolic Increased 13 3.2 3.2 signal
129 Incontinence 7 3.2 3.2 signal
130 Hypomagnesaemia 9 3.1 3.1 signal
131 Ascites 19 3.1 3.1 signal
132 Erythema Multiforme 6 3.1 3.1 signal
133 Oesophagitis 7 3.1 3.1 signal
134 Lymphopenia 9 3.1 3.1 signal
135 Sinus Tachycardia 9 3.1 3.1 signal
136 White Blood Cell Count Increased 24 3.0 3.0 signal
137 Choking 12 3.0 3.0 signal
138 Mental Status Changes 17 3.0 3.0 signal
139 Incorrect Route Of Product Administration 10 2.9 2.9 signal
140 Cardiac Failure 47 2.8 2.9 signal
141 Dialysis 8 2.7 2.7 signal
142 Unresponsive To Stimuli 14 2.6 2.6 signal
143 Coagulopathy 9 2.6 2.6 signal
144 Ventricular Fibrillation 6 2.6 2.6 signal
145 Thrombocytopenia 60 2.6 2.6 signal
146 Grand Mal Convulsion 5 2.6 2.6 no signal
147 Respiratory Disorder 16 2.6 2.6 signal
148 Chronic Kidney Disease 40 2.5 2.5 signal
149 Gastric Haemorrhage 6 2.5 2.5 signal
150 Tachypnoea 7 2.5 2.5 signal
151 Post Procedural Haemorrhage 6 2.5 2.5 no signal
152 Blood Creatine Phosphokinase Increased 15 2.5 2.5 signal
153 Eyelid Oedema 6 2.5 2.5 no signal
154 Disorientation 20 2.4 2.4 signal
155 Dementia 14 2.4 2.4 signal
156 Melaena 11 2.4 2.4 signal
157 Brain Injury 5 2.4 2.4 no signal
158 Interstitial Lung Disease 24 2.4 2.4 signal
159 Bone Marrow Failure 10 2.4 2.4 signal
160 Paralysis 7 2.4 2.4 signal
161 Peritonitis 10 2.3 2.3 signal
162 Injection Site Extravasation 6 2.3 2.3 no signal
163 Injection Site Haematoma 7 2.3 2.3 no signal
164 Acute Myocardial Infarction 14 2.3 2.3 signal
165 Neutropenia 63 2.3 2.3 signal
166 Neurotoxicity 8 2.2 2.2 signal
167 Electrocardiogram Qt Prolonged 16 2.2 2.2 signal
168 Myocarditis 5 2.1 2.1 no signal
169 Intentional Overdose 27 2.1 2.1 signal
170 Mucosal Inflammation 11 2.0 2.0 signal
171 Upper Gastrointestinal Haemorrhage 7 2.0 2.0 no signal
172 Parkinsonism 4 2.0 2.0 no signal
173 Hypoglycaemia 19 1.9 1.9 no signal
174 Mydriasis 5 1.9 1.9 no signal
175 Folliculitis 4 1.9 1.9 no signal
176 Pharyngeal Oedema 6 1.9 1.9 no signal
177 Generalised Tonic-clonic Seizure 6 1.8 1.8 no signal
178 Serotonin Syndrome 7 1.8 1.8 no signal
179 Gastrointestinal Haemorrhage 30 1.7 1.7 no signal
180 Rash Papular 8 1.7 1.7 no signal
181 Product Prescribing Error 8 1.6 1.6 no signal
182 No Therapeutic Response 4 1.6 1.6 no signal
183 Product Dispensing Error 7 1.6 1.6 no signal
184 Haemorrhage 33 1.5 1.5 no signal
185 Knee Operation 3 1.5 1.5 no signal
186 Diabetes Mellitus Inadequate Control 5 1.4 1.4 no signal
187 Toxicity To Various Agents 47 1.4 1.4 no signal
188 Sedation 7 1.3 1.3 no signal
189 Diabetic Ketoacidosis 6 1.2 1.2 no signal
190 Drug Withdrawal Syndrome Neonatal 3 1.0 1.0 no signal
191 Extrapyramidal Disorder 5 1.0 1.0 no signal
192 Device Failure 3 1.0 1.0 no signal
193 Withdrawal Syndrome 7 0.8 0.8 no signal
194 Suicide Attempt 10 0.8 0.8 no signal
195 Gynaecomastia 5 0.8 0.8 no signal
196 Completed Suicide 12 0.7 0.7 no signal