Drug

Nitric Oxide

91 flagged reaction(s) · 6,479 total co-reports · max PRR 45.9

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Device Failure	147	45.9	47.4	signal
2	Device Malfunction	636	44.8	52.0	signal
3	Pulmonary Hypertension	151	34.1	35.2	signal
4	Underdose	444	28.7	31.7	signal
5	Device Issue	452	24.4	27.0	signal
6	Oxygen Saturation Decreased	270	22.8	24.2	signal
7	Device Delivery System Issue	122	22.0	22.6	signal
8	No Adverse Event	789	20.9	25.2	signal
9	Acute Respiratory Distress Syndrome	67	17.8	18.1	signal
10	Hypoxia	132	17.7	18.2	signal
11	Pneumothorax	59	17.5	17.7	signal
12	Pulmonary Arterial Hypertension	48	15.5	15.7	signal
13	Pulmonary Congestion	35	12.4	12.5	signal
14	Multiple Organ Dysfunction Syndrome	73	12.3	12.5	signal
15	Device Occlusion	34	11.5	11.6	signal
16	Atelectasis	23	11.1	11.2	signal
17	Premature Baby	70	10.9	11.0	signal
18	Premature Delivery	37	10.9	10.9	signal
19	Cardiogenic Shock	33	10.9	10.9	signal
20	Respiratory Failure	144	9.3	9.5	signal
21	Product Use Issue	368	9.2	10.0	signal
22	Therapy Non-responder	76	8.0	8.1	signal
23	Intestinal Perforation	19	7.9	8.0	signal
24	Cardio-respiratory Arrest	71	7.9	8.0	signal
25	Pulmonary Oedema	71	7.4	7.5	signal
26	Drug Ineffective For Unapproved Indication	84	7.1	7.2	signal
27	Coagulopathy	24	6.8	6.8	signal
28	Disseminated Intravascular Coagulation	20	6.6	6.7	signal
29	Cardiac Arrest	117	6.6	6.8	signal
30	Shock	27	5.6	5.6	signal
31	Rebound Effect	13	5.4	5.4	signal
32	Hypophagia	29	5.4	5.4	signal
33	Transfusion	12	5.4	5.4	signal
34	Lactic Acidosis	36	5.3	5.3	signal
35	Caesarean Section	13	5.2	5.2	signal
36	Ventricular Fibrillation	12	5.1	5.1	signal
37	Bacteraemia	12	4.8	4.8	signal
38	Septic Shock	44	4.8	4.8	signal
39	Circulatory Collapse	17	4.7	4.7	signal
40	Generalised Oedema	12	4.6	4.6	signal
41	No Therapeutic Response	12	4.5	4.6	signal
42	Blood Urea Increased	15	4.2	4.2	signal
43	Bradycardia	46	4.1	4.1	signal
44	Post Procedural Haemorrhage	10	4.0	4.0	signal
45	Product Use In Unapproved Indication	208	4.0	4.1	signal
46	Heart Rate Decreased	30	4.0	4.0	signal
47	Respiratory Distress	22	3.7	3.8	signal
48	Foetal Exposure During Pregnancy	61	3.5	3.6	signal
49	Multi-organ Failure	13	3.5	3.5	signal
50	Blood Pressure Decreased	49	3.5	3.5	signal
51	Cerebral Haemorrhage	26	3.4	3.4	signal
52	Hypotension	140	3.3	3.4	signal
53	Fluid Overload	10	3.2	3.2	signal
54	Ventricular Extrasystoles	7	3.2	3.2	signal
55	Covid-19 Pneumonia	8	3.2	3.2	signal
56	Tachypnoea	9	3.1	3.1	signal
57	Ventricular Tachycardia	11	3.1	3.1	signal
58	Maternal Exposure During Pregnancy	56	3.0	3.0	signal
59	Cyanosis	10	3.0	3.0	signal
60	Supraventricular Tachycardia	6	2.9	2.9	signal
61	Pallor	17	2.9	2.9	signal
62	Thrombotic Microangiopathy	6	2.9	2.9	signal
63	Condition Aggravated	186	2.9	3.0	signal
64	Hepatomegaly	6	2.8	2.9	signal
65	Metabolic Acidosis	19	2.8	2.8	signal
66	Exposure During Pregnancy	37	2.8	2.8	signal
67	Emphysema	6	2.8	2.8	signal
68	Intentional Overdose	37	2.7	2.7	signal
69	Haemoptysis	15	2.5	2.5	signal
70	Pulmonary Fibrosis	10	2.5	2.5	signal
71	Device Related Infection	8	2.4	2.4	signal
72	Pneumocystis Jirovecii Pneumonia	5	2.3	2.3	no signal
73	Hyperbilirubinaemia	5	2.3	2.3	no signal
74	Drug Level Increased	8	2.3	2.3	signal
75	Post Procedural Complication	9	2.2	2.2	signal
76	Cardiac Failure	37	2.2	2.2	signal
77	Death	383	2.1	2.2	signal
78	Myocarditis	5	2.1	2.1	no signal
79	Haemorrhage Intracranial	6	1.9	1.9	no signal
80	Mydriasis	5	1.8	1.8	no signal
81	Complication Associated With Device	5	1.8	1.8	no signal
82	Cerebral Infarction	9	1.7	1.7	no signal
83	Interstitial Lung Disease	17	1.6	1.7	no signal
84	Genital Haemorrhage	4	1.4	1.4	no signal
85	Device Leakage	9	1.0	1.0	no signal
86	Drug Effective For Unapproved Indication	6	1.0	1.0	no signal
87	Drug Withdrawal Syndrome Neonatal	3	0.9	0.9	no signal
88	Drug Exposure During Pregnancy	5	0.7	0.7	no signal
89	Wrong Technique In Device Usage Process	6	0.6	0.6	no signal
90	Completed Suicide	9	0.5	0.5	no signal
91	Device Breakage	4	0.5	0.5	no signal