OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pegvisomant

237 flagged reaction(s) · 10,417 total co-reports · max PRR 36.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Needle Issue 201 36.3 38.1 signal
2 Helicobacter Infection 57 28.8 29.2 signal
3 Injection Site Discomfort 54 26.9 27.3 signal
4 Neoplasm 54 24.1 24.4 signal
5 Bladder Disorder 42 21.7 21.9 signal
6 Brain Neoplasm 36 20.1 20.3 signal
7 Thyroid Disorder 53 17.7 17.9 signal
8 Peripheral Coldness 47 17.5 17.7 signal
9 Poor Quality Product Administered 34 17.1 17.2 signal
10 Mass 46 16.9 17.0 signal
11 Gallbladder Disorder 58 16.6 16.9 signal
12 Blood Pressure Systolic Increased 62 16.3 16.5 signal
13 Blood Glucose Fluctuation 33 15.4 15.5 signal
14 Heart Rate Decreased 103 15.0 15.4 signal
15 Musculoskeletal Discomfort 47 14.0 14.2 signal
16 Neoplasm Progression 95 13.9 14.2 signal
17 Bone Disorder 49 13.7 13.8 signal
18 Cholelithiasis 87 13.6 13.9 signal
19 Injection Site Mass 91 12.7 12.9 signal
20 Syringe Issue 42 12.3 12.4 signal
21 Nocturia 28 11.9 11.9 signal
22 Sleep Apnoea Syndrome 42 11.3 11.4 signal
23 Wound Infection 23 10.9 10.9 signal
24 Glycosylated Haemoglobin Increased 53 10.8 10.9 signal
25 Full Blood Count Decreased 42 10.7 10.8 signal
26 Incorrect Route Of Product Administration 35 10.7 10.8 signal
27 Faeces Discoloured 45 10.7 10.8 signal
28 Diabetes Mellitus 147 9.9 10.2 signal
29 Body Temperature Decreased 19 9.8 9.9 signal
30 Brain Injury 18 9.2 9.2 signal
31 Jaundice 48 9.1 9.2 signal
32 Limb Discomfort 55 9.1 9.2 signal
33 Injection Site Bruising 139 9.0 9.3 signal
34 Product Dose Omission In Error 47 9.0 9.1 signal
35 Device Leakage 72 8.7 8.9 signal
36 Tooth Abscess 17 8.5 8.6 signal
37 Foot Deformity 18 8.3 8.4 signal
38 Injection Site Induration 21 8.3 8.3 signal
39 Hepatic Enzyme Increased 110 8.3 8.5 signal
40 Urinary Incontinence 42 7.3 7.3 signal
41 Tendonitis 22 7.3 7.3 signal
42 Musculoskeletal Pain 74 7.2 7.3 signal
43 Bone Pain 82 7.2 7.3 signal
44 Device Defective 22 7.0 7.0 signal
45 Blood Pressure Increased 205 6.9 7.2 signal
46 Lung Neoplasm Malignant 55 6.8 6.9 signal
47 Dysuria 49 6.8 6.9 signal
48 Blood Glucose Decreased 64 6.8 6.9 signal
49 Blood Triglycerides Increased 21 6.1 6.1 signal
50 Feeling Cold 33 6.1 6.1 signal
51 Eating Disorder 25 6.0 6.0 signal
52 Stress 84 6.0 6.1 signal
53 Eructation 22 5.9 6.0 signal
54 Arthritis 87 5.7 5.8 signal
55 Blood Iron Decreased 13 5.7 5.7 signal
56 Product Use Issue 203 5.6 5.8 signal
57 Sciatica 17 5.5 5.5 signal
58 Gastroenteritis Viral 19 5.4 5.4 signal
59 Blood Cholesterol Increased 48 5.3 5.3 signal
60 Blood Glucose Abnormal 19 5.3 5.3 signal
61 Blood Test Abnormal 14 5.1 5.1 signal
62 Liver Function Test Increased 21 5.0 5.1 signal
63 Iron Deficiency Anaemia 9 5.0 5.0 signal
64 Product Dispensing Error 21 5.0 5.0 signal
65 Intentional Dose Omission 26 4.9 4.9 signal
66 Intentional Product Misuse 82 4.8 4.9 signal
67 Product Dose Omission Issue 268 4.8 5.1 signal
68 Hyperhidrosis 121 4.8 4.9 signal
69 Limb Injury 25 4.7 4.8 signal
70 Hip Arthroplasty 14 4.7 4.7 signal
71 Ocular Discomfort 10 4.7 4.7 signal
72 Therapeutic Product Effect Incomplete 64 4.6 4.7 signal
73 Abdominal Distension 92 4.5 4.6 signal
74 Temperature Intolerance 9 4.5 4.5 signal
75 Cholecystectomy 10 4.5 4.5 signal
76 Body Temperature Increased 18 4.5 4.5 signal
77 Illness 88 4.5 4.6 signal
78 Contusion 83 4.4 4.5 signal
79 Injection Site Pain 261 4.4 4.6 signal
80 Injection Site Reaction 59 4.4 4.5 signal
81 Hepatotoxicity 19 4.4 4.4 signal
82 Device Breakage 33 4.3 4.3 signal
83 Adrenal Insufficiency 10 4.3 4.3 signal
84 Peripheral Swelling 128 4.3 4.4 signal
85 Bursitis 10 4.2 4.3 signal
86 Injection Site Haemorrhage 65 4.2 4.3 signal
87 Product Dose Omission 53 4.1 4.1 signal
88 Blood Calcium Decreased 9 4.1 4.1 signal
89 Ear Pain 15 4.0 4.0 signal
90 Skeletal Injury 8 3.9 3.9 signal
91 Product Complaint 19 3.9 3.9 signal
92 Cholecystitis 9 3.9 3.9 signal
93 Blood Pressure Abnormal 15 3.9 3.9 signal
94 Blood Sodium Decreased 14 3.8 3.8 signal
95 Arthralgia 300 3.7 3.9 signal
96 Prescribed Overdose 14 3.7 3.7 signal
97 Neoplasm Malignant 48 3.7 3.7 signal
98 Vitamin D Deficiency 7 3.7 3.7 signal
99 Blood Urea Increased 12 3.7 3.7 signal
100 Ligament Sprain 7 3.6 3.6 signal
101 Blood Pressure Fluctuation 17 3.6 3.6 signal
102 Drug Resistance 18 3.6 3.6 signal
103 Nephrolithiasis 32 3.6 3.6 signal
104 Underdose 51 3.6 3.6 signal
105 Sluggishness 7 3.5 3.5 signal
106 Cardiac Failure 55 3.5 3.5 signal
107 Injection Site Haematoma 10 3.5 3.5 signal
108 Drug Intolerance 64 3.4 3.4 signal
109 Neck Pain 37 3.4 3.4 signal
110 Incontinence 7 3.4 3.4 signal
111 Glomerular Filtration Rate Decreased 8 3.4 3.4 signal
112 Body Height Decreased 7 3.3 3.3 signal
113 Product Packaging Issue 6 3.3 3.3 signal
114 Cardiomegaly 8 3.3 3.3 signal
115 Blood Alkaline Phosphatase Increased 16 3.3 3.3 signal
116 Headache 402 3.3 3.5 signal
117 Gait Disturbance 123 3.3 3.4 signal
118 Bradycardia 34 3.3 3.3 signal
119 Blood Glucose Increased 121 3.3 3.3 signal
120 Injection Site Nodule 7 3.3 3.3 signal
121 Flatulence 36 3.3 3.3 signal
122 Eye Inflammation 6 3.3 3.3 signal
123 Device Use Issue 11 3.3 3.3 signal
124 Wrong Technique In Device Usage Process 29 3.3 3.3 signal
125 Drug Dose Omission By Device 48 3.2 3.2 signal
126 Laboratory Test Abnormal 18 3.1 3.1 signal
127 Incorrect Product Storage 8 3.1 3.1 signal
128 Atrial Fibrillation 58 3.0 3.1 signal
129 Haemorrhage 62 3.0 3.1 signal
130 Muscular Weakness 67 3.0 3.1 signal
131 Joint Swelling 71 3.0 3.1 signal
132 Back Pain 137 3.0 3.1 signal
133 Hyperglycaemia 21 3.0 3.0 signal
134 Haemoglobin Decreased 59 2.9 3.0 signal
135 Influenza 64 2.9 3.0 signal
136 Libido Decreased 7 2.9 2.9 signal
137 Diabetes Mellitus Inadequate Control 10 2.9 2.9 signal
138 Injection Site Discolouration 7 2.9 2.9 signal
139 Off Label Use 489 2.9 3.1 signal
140 Type 2 Diabetes Mellitus 19 2.9 2.9 signal
141 Abdominal Discomfort 94 2.9 2.9 signal
142 Joint Injury 12 2.9 2.9 signal
143 Subdural Haematoma 8 2.9 2.9 signal
144 Paralysis 8 2.9 2.9 signal
145 Product Physical Issue 11 2.8 2.8 signal
146 Back Disorder 9 2.8 2.8 signal
147 Product Prescribing Error 13 2.8 2.8 signal
148 Hepatitis 14 2.8 2.8 signal
149 Nasopharyngitis 101 2.8 2.8 signal
150 Swelling 51 2.8 2.8 signal
151 Injection Site Swelling 41 2.8 2.8 signal
152 Abdominal Pain Upper 110 2.7 2.8 signal
153 Hepatic Cirrhosis 10 2.7 2.7 signal
154 Urinary Tract Infection 90 2.7 2.8 signal
155 Rhinorrhoea 34 2.7 2.7 signal
156 Hypoaesthesia 79 2.7 2.7 signal
157 Hunger 7 2.7 2.7 signal
158 Inappropriate Schedule Of Product Administration 92 2.7 2.7 signal
159 Arthropathy 29 2.7 2.7 signal
160 Hypoglycaemia 25 2.6 2.6 signal
161 Fatigue 385 2.5 2.7 signal
162 Thyroid Cancer 6 2.5 2.5 signal
163 Weight Increased 110 2.5 2.6 signal
164 Chromaturia 11 2.5 2.5 signal
165 Product Preparation Error 10 2.5 2.5 signal
166 Brain Fog 7 2.5 2.5 signal
167 Liver Function Test Abnormal 14 2.5 2.5 signal
168 Device Mechanical Issue 6 2.4 2.4 no signal
169 Oropharyngeal Pain 43 2.4 2.4 signal
170 Pain In Jaw 13 2.3 2.4 signal
171 Gastrointestinal Pain 5 2.3 2.3 no signal
172 Malaise 200 2.3 2.4 signal
173 Upper Limb Fracture 9 2.3 2.3 signal
174 Rash Papular 10 2.3 2.3 signal
175 Therapeutic Response Unexpected 20 2.3 2.3 signal
176 Injection Site Pruritus 29 2.2 2.2 signal
177 Diverticulitis 12 2.2 2.2 signal
178 Hepatic Function Abnormal 16 2.2 2.2 signal
179 Carpal Tunnel Syndrome 6 2.2 2.2 no signal
180 Nasal Congestion 25 2.2 2.2 signal
181 Feeling Abnormal 102 2.2 2.2 signal
182 Depressed Mood 22 2.1 2.1 signal
183 Transient Ischaemic Attack 14 2.1 2.1 signal
184 Covid-19 72 2.1 2.1 signal
185 Product Administration Error 8 2.1 2.1 no signal
186 Exposure Via Skin Contact 9 2.0 2.0 no signal
187 Injection Site Rash 12 2.0 2.0 signal
188 Injection Site Irritation 5 2.0 2.0 no signal
189 Erectile Dysfunction 10 2.0 2.0 no signal
190 Hip Fracture 12 1.9 1.9 no signal
191 Device Issue 32 1.9 1.9 no signal
192 Product Packaging Quantity Issue 4 1.9 1.9 no signal
193 Hernia 7 1.9 1.9 no signal
194 Device Difficult To Use 24 1.9 1.9 no signal
195 Drug Effect Less Than Expected 5 1.8 1.8 no signal
196 Incorrect Dose Administered By Device 9 1.8 1.8 no signal
197 Drug Effect Incomplete 13 1.8 1.8 no signal
198 Gastric Disorder 12 1.8 1.8 no signal
199 Spinal Operation 4 1.7 1.7 no signal
200 Blood Thyroid Stimulating Hormone Increased 3 1.7 1.7 no signal
201 Nervousness 17 1.7 1.7 no signal
202 Emotional Disorder 10 1.7 1.7 no signal
203 Blindness 13 1.6 1.6 no signal
204 Affect Lability 3 1.6 1.6 no signal
205 Knee Operation 3 1.6 1.6 no signal
206 Decreased Immune Responsiveness 3 1.6 1.6 no signal
207 Hypoacusis 13 1.6 1.6 no signal
208 Influenza Like Illness 25 1.5 1.6 no signal
209 Cerebrovascular Accident 51 1.5 1.5 no signal
210 Injury Associated With Device 6 1.5 1.5 no signal
211 Ovarian Cyst 3 1.5 1.5 no signal
212 Injection Site Erythema 36 1.5 1.5 no signal
213 Knee Arthroplasty 6 1.5 1.5 no signal
214 Cardiac Disorder 27 1.5 1.5 no signal
215 Breast Pain 3 1.4 1.4 no signal
216 Hepatocellular Injury 4 1.4 1.4 no signal
217 Product Administered At Inappropriate Site 5 1.4 1.4 no signal
218 Device Malfunction 18 1.4 1.4 no signal
219 Menorrhagia 5 1.3 1.3 no signal
220 Incorrect Route Of Drug Administration 9 1.3 1.3 no signal
221 Product Quality Issue 33 1.3 1.3 no signal
222 Injection Site Warmth 5 1.2 1.2 no signal
223 Amenorrhoea 4 1.2 1.2 no signal
224 Diabetic Ketoacidosis 5 1.1 1.1 no signal
225 Inappropriate Schedule Of Drug Administration 15 1.1 1.1 no signal
226 Incorrect Dose Administered 45 1.0 1.0 no signal
227 Breast Cancer 17 0.9 0.9 no signal
228 Pancreatic Carcinoma 5 0.9 0.9 no signal
229 Abortion Spontaneous 6 0.8 0.8 no signal
230 Circumstance Or Information Capable Of Leading To Medication Error 5 0.8 0.8 no signal
231 Injection Site Urticaria 3 0.6 0.6 no signal
232 Device Use Error 4 0.6 0.6 no signal
233 Gastric Cancer 3 0.6 0.6 no signal
234 Product Storage Error 9 0.5 0.5 no signal
235 Prostate Cancer 8 0.5 0.5 no signal
236 Accidental Exposure To Product 9 0.5 0.5 no signal
237 Renal Cancer 4 0.4 0.4 no signal