OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pemetrexed

1,028 flagged reaction(s) · 62,347 total co-reports · max PRR 658.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Erosive Pustular Dermatosis 19 658.0 658.6 signal
2 Pseudocellulitis 68 467.7 469.2 signal
3 Scleroedema 12 253.0 253.1 signal
4 Heteroplasia 8 250.2 250.3 signal
5 Brain Radiation Necrosis 13 225.1 225.2 signal
6 Flagellate Dermatitis 9 158.7 158.7 signal
7 Lung Adenocarcinoma Recurrent 13 157.6 157.7 signal
8 Immune-mediated Oesophagitis 8 146.4 146.4 signal
9 Meningitis Noninfective 8 143.7 143.7 signal
10 Malignant Neoplasm Oligoprogression 22 141.3 141.4 signal
11 Autoimmune Lung Disease 14 135.8 135.8 signal
12 Egfr Gene Mutation 44 129.7 130.0 signal
13 Scleroderma-like Reaction 17 120.3 120.4 signal
14 K-ras Gene Mutation 8 109.3 109.3 signal
15 Lung Adenocarcinoma Stage Iv 37 106.2 106.3 signal
16 Endocrine Toxicity 9 97.0 97.0 signal
17 Bilirubinuria 9 92.8 92.9 signal
18 Hyperphosphaturia 10 90.6 90.7 signal
19 Immune-mediated Lung Disease 147 90.3 91.0 signal
20 Tracheal Fistula 13 90.0 90.1 signal
21 Myocarditis-myositis-myasthenia Gravis Overlap Syndrome 15 88.7 88.8 signal
22 Immune-mediated Dermatitis 74 84.4 84.7 signal
23 Non-small Cell Lung Cancer Metastatic 61 75.1 75.3 signal
24 Non-small Cell Lung Cancer 332 74.2 75.4 signal
25 Malignant Transformation 31 73.0 73.1 signal
26 Immune-mediated Neuropathy 10 72.4 72.4 signal
27 Acquired Gene Mutation 86 68.5 68.8 signal
28 Non-small Cell Lung Cancer Recurrent 18 68.2 68.2 signal
29 Leukaemia Cutis 10 67.8 67.8 signal
30 Immune-mediated Gastritis 12 67.7 67.7 signal
31 Drug Resistance Mutation 11 65.4 65.5 signal
32 Immune-mediated Arthritis 22 62.2 62.3 signal
33 Microvascular Coronary Artery Disease 12 59.7 59.7 signal
34 Autoimmune Nephritis 12 57.3 57.4 signal
35 Autoimmune Dermatitis 8 55.8 55.8 signal
36 Non-small Cell Lung Cancer Stage Iv 19 54.7 54.7 signal
37 Diabetic Ketoacidotic Hyperglycaemic Coma 9 51.3 51.4 signal
38 Immune-mediated Hypothyroidism 53 51.0 51.1 signal
39 Immune-mediated Nephritis 22 50.2 50.2 signal
40 Immune-mediated Hepatitis 94 49.4 49.6 signal
41 Hypercreatininaemia 23 47.6 47.6 signal
42 Tumour Pseudoprogression 50 47.4 47.6 signal
43 Dermo-hypodermitis 27 46.9 47.0 signal
44 Pleural Adhesion 9 46.2 46.2 signal
45 Cancer Fatigue 10 45.3 45.3 signal
46 Lung Adenocarcinoma 133 45.3 45.6 signal
47 Immune-mediated Enterocolitis 151 44.0 44.3 signal
48 Immune-mediated Renal Disorder 16 41.9 42.0 signal
49 Pleural Mesothelioma Malignant 12 41.9 41.9 signal
50 Tumour Associated Fever 16 40.9 41.0 signal
51 Febrile Bone Marrow Aplasia 157 38.3 38.6 signal
52 Xeroderma 10 37.7 37.7 signal
53 Superior Mesenteric Artery Syndrome 8 36.8 36.8 signal
54 Neonatal Respiratory Depression 12 36.4 36.4 signal
55 Immune-mediated Cholangitis 12 35.9 35.9 signal
56 Acute Interstitial Pneumonitis 18 35.0 35.0 signal
57 Autoimmune Hypothyroidism 8 34.8 34.8 signal
58 Lichenoid Keratosis 77 34.7 34.8 signal
59 Immune-mediated Thyroiditis 16 34.7 34.7 signal
60 Cellulite 11 34.5 34.5 signal
61 Lung Adenocarcinoma Metastatic 8 34.5 34.5 signal
62 Metastases To Adrenals 31 34.3 34.4 signal
63 Primary Adrenal Insufficiency 10 34.1 34.2 signal
64 Radiation Necrosis 19 33.9 34.0 signal
65 Immune-mediated Adrenal Insufficiency 25 33.7 33.7 signal
66 Superior Vena Cava Syndrome 20 33.6 33.6 signal
67 Myasthenic Syndrome 25 33.3 33.4 signal
68 Spinal Cord Abscess 9 33.2 33.2 signal
69 Immune-mediated Pancreatitis 12 33.1 33.1 signal
70 Subacute Cutaneous Lupus Erythematosus 57 32.8 32.9 signal
71 Autoimmune Myocarditis 7 32.5 32.5 signal
72 Secondary Hypertension 9 32.1 32.1 signal
73 Hypophysitis 63 31.8 31.9 signal
74 Glucocorticoid Deficiency 13 31.8 31.8 signal
75 Metastases To The Mediastinum 13 31.8 31.8 signal
76 Lymphangiosis Carcinomatosa 32 31.1 31.2 signal
77 Immune-mediated Hypophysitis 13 30.7 30.8 signal
78 Eastern Cooperative Oncology Group Performance Status Worsened 37 30.2 30.2 signal
79 Autoimmune Colitis 19 29.9 29.9 signal
80 Peptic Ulcer Perforation 9 29.9 29.9 signal
81 Visceral Leishmaniasis 21 29.7 29.8 signal
82 Nephritis 97 29.7 29.8 signal
83 Ocular Myasthenia 10 29.4 29.4 signal
84 Bronchopleural Fistula 11 29.4 29.4 signal
85 Bronchostenosis 16 29.3 29.4 signal
86 Lymphocytic Hypophysitis 8 29.3 29.3 signal
87 Metastases To Pleura 30 29.1 29.2 signal
88 Systemic Scleroderma 20 28.1 28.1 signal
89 Thrombophlebitis Migrans 9 28.1 28.1 signal
90 Adrenocorticotropic Hormone Deficiency 24 27.8 27.8 signal
91 Immune-mediated Hepatic Disorder 52 27.5 27.5 signal
92 Radiation Oesophagitis 10 26.6 26.6 signal
93 Gene Mutation 52 26.4 26.5 signal
94 Immune-mediated Myocarditis 40 26.2 26.3 signal
95 Therapy Partial Responder 387 25.9 26.4 signal
96 Skin Toxicity 143 25.9 26.0 signal
97 Hyperamylasaemia 14 25.8 25.8 signal
98 Oesophageal Fistula 8 25.4 25.4 signal
99 Paraneoplastic Syndrome 17 25.3 25.3 signal
100 Malignant Pleural Effusion 42 25.2 25.2 signal
101 Aortitis 17 25.1 25.1 signal
102 Haematotoxicity 225 24.4 24.7 signal
103 Immune-mediated Encephalitis 12 24.4 24.4 signal
104 Metastases To Meninges 54 24.3 24.3 signal
105 Radiation Pneumonitis 51 23.9 24.0 signal
106 Granulocyte Count Increased 9 22.3 22.3 signal
107 Paronychia 96 22.3 22.4 signal
108 Neutropenic Colitis 45 22.0 22.0 signal
109 Blood Phosphorus Abnormal 10 21.6 21.6 signal
110 Immune-mediated Adverse Reaction 30 20.6 20.6 signal
111 Hypopituitarism 35 20.1 20.2 signal
112 Hepatic Cytolysis 244 20.0 20.2 signal
113 Bicytopenia 38 19.7 19.7 signal
114 Secondary Adrenocortical Insufficiency 29 19.4 19.4 signal
115 Pneumonitis 523 19.4 19.8 signal
116 Renal Tubular Necrosis 189 19.3 19.4 signal
117 Candida Test Positive 8 19.1 19.1 signal
118 Superinfection Bacterial 15 19.0 19.0 signal
119 Stasis Dermatitis 13 19.0 19.0 signal
120 Tubulointerstitial Nephritis 352 18.8 19.1 signal
121 Hypergammaglobulinaemia 9 18.8 18.8 signal
122 Tracheo-oesophageal Fistula 12 18.7 18.7 signal
123 Radiotherapy 35 18.3 18.3 signal
124 Pulmonary Artery Thrombosis 14 18.1 18.2 signal
125 Hypersensitivity Pneumonitis 20 17.7 17.7 signal
126 Heart Failure With Reduced Ejection Fraction 8 17.5 17.5 signal
127 Epidermolysis 8 17.5 17.5 signal
128 Superficial Vein Thrombosis 14 17.4 17.4 signal
129 Necrotising Myositis 15 17.3 17.3 signal
130 Pancytopenia 959 17.2 18.0 signal
131 Extremity Necrosis 30 17.1 17.1 signal
132 Enterococcus Test Positive 11 16.9 16.9 signal
133 Myeloproliferative Neoplasm 11 16.8 16.8 signal
134 Unmasking Of Previously Unidentified Disease 18 16.8 16.8 signal
135 Ototoxicity 31 16.7 16.7 signal
136 Malignant Neoplasm Progression 1,689 16.6 17.9 signal
137 Metastases To Central Nervous System 212 16.5 16.7 signal
138 Ocular Toxicity 17 16.1 16.1 signal
139 Adenocarcinoma 36 16.0 16.0 signal
140 Hypertransaminasaemia 109 16.0 16.1 signal
141 Gastrointestinal Toxicity 74 15.7 15.7 signal
142 Renal Tubular Disorder 43 15.2 15.2 signal
143 Intestinal Pseudo-obstruction 13 15.1 15.1 signal
144 Aortic Thrombosis 17 14.6 14.6 signal
145 Oesophagitis Ulcerative 10 14.5 14.5 signal
146 Overlap Syndrome 10 14.5 14.5 signal
147 Metastases To Kidney 8 14.4 14.4 signal
148 Systemic Infection 24 14.4 14.4 signal
149 Thyroxine Free Decreased 8 14.4 14.4 signal
150 Duodenal Perforation 14 14.4 14.4 signal
151 Squamous Cell Carcinoma Of Lung 11 14.3 14.3 signal
152 Erysipelas 72 14.2 14.3 signal
153 Lymphadenopathy Mediastinal 27 14.2 14.2 signal
154 Renal Tubular Injury 16 13.8 13.8 signal
155 Pulmonary Toxicity 97 13.8 13.8 signal
156 Urinary Tract Infection Enterococcal 13 13.8 13.8 signal
157 Mediastinitis 8 13.7 13.7 signal
158 Fulminant Type 1 Diabetes Mellitus 14 13.7 13.7 signal
159 Dose Calculation Error 8 13.6 13.6 signal
160 Lung Cancer Metastatic 39 13.5 13.5 signal
161 Nephropathy Toxic 150 13.4 13.5 signal
162 Adrenal Adenoma 8 13.4 13.4 signal
163 Kidney Fibrosis 23 13.2 13.3 signal
164 Oesophageal Perforation 11 13.2 13.2 signal
165 Hydrothorax 11 13.1 13.1 signal
166 Febrile Infection 15 13.0 13.0 signal
167 Haemophagocytic Lymphohistiocytosis 94 13.0 13.0 signal
168 Small Cell Lung Cancer 19 12.9 13.0 signal
169 Neutropenic Sepsis 93 12.9 13.0 signal
170 Hyperthyroidism 183 12.6 12.7 signal
171 Embolism Venous 38 12.5 12.5 signal
172 Bone Marrow Toxicity 15 12.4 12.4 signal
173 Foetal Exposure Timing Unspecified 9 12.4 12.4 signal
174 Dermatitis Acneiform 75 12.3 12.4 signal
175 Tumour Necrosis 13 12.3 12.3 signal
176 Myelosuppression 420 12.3 12.5 signal
177 Peritoneal Disorder 8 12.2 12.2 signal
178 Palmar Erythema 14 12.1 12.2 signal
179 Myocardial Injury 12 12.0 12.0 signal
180 Aplasia 24 12.0 12.0 signal
181 Tumour Flare 8 11.6 11.7 signal
182 Febrile Neutropenia 756 11.3 11.7 signal
183 Bronchial Carcinoma 9 11.3 11.3 signal
184 Gouty Arthritis 9 11.2 11.2 signal
185 Mucosal Inflammation 294 11.2 11.4 signal
186 Drug Resistance 289 11.2 11.3 signal
187 Administration Site Extravasation 11 11.1 11.1 signal
188 Myocarditis 124 10.9 10.9 signal
189 Performance Status Decreased 51 10.8 10.9 signal
190 Leukocyturia 9 10.8 10.8 signal
191 Embolism Arterial 13 10.7 10.7 signal
192 Nephrosclerosis 12 10.6 10.6 signal
193 Lung Consolidation 29 10.2 10.2 signal
194 Immune Thrombocytopenia 46 10.2 10.2 signal
195 Cancer Pain 26 10.1 10.1 signal
196 Multiple-drug Resistance 31 9.9 10.0 signal
197 N-terminal Prohormone Brain Natriuretic Peptide Increased 14 9.9 9.9 signal
198 Oesophagitis 109 9.9 9.9 signal
199 Hyperplasia 9 9.9 9.9 signal
200 Monocyte Count Decreased 12 9.8 9.8 signal
201 Adrenal Disorder 19 9.8 9.8 signal
202 Carcinoembryonic Antigen Increased 19 9.8 9.8 signal
203 Anal Ulcer 8 9.7 9.7 signal
204 Nephrogenic Diabetes Insipidus 11 9.5 9.5 signal
205 Disease Progression 1,119 9.4 9.9 signal
206 Adrenal Insufficiency 113 9.4 9.4 signal
207 Neoplasm Progression 331 9.4 9.5 signal
208 Autoimmune Haemolytic Anaemia 32 9.3 9.3 signal
209 Peripheral Ischaemia 38 9.2 9.2 signal
210 Hilar Lymphadenopathy 8 9.1 9.1 signal
211 Interstitial Lung Disease 443 9.1 9.3 signal
212 Glomerulonephritis Rapidly Progressive 10 9.1 9.1 signal
213 Type 1 Diabetes Mellitus 55 9.1 9.1 signal
214 Large Intestine Infection 11 9.1 9.1 signal
215 Pharyngeal Inflammation 11 9.0 9.0 signal
216 Hypothyroidism 289 9.0 9.1 signal
217 Small Intestinal Perforation 17 9.0 9.0 signal
218 Hepatotoxicity 200 8.9 9.0 signal
219 Vanishing Bile Duct Syndrome 10 8.9 8.9 signal
220 Pulmonary Sepsis 13 8.9 8.9 signal
221 Mixed Liver Injury 26 8.9 8.9 signal
222 Peripheral Sensorimotor Neuropathy 11 8.8 8.8 signal
223 Enteritis 56 8.7 8.8 signal
224 Hypoalbuminaemia 67 8.7 8.7 signal
225 Pleural Fibrosis 9 8.7 8.7 signal
226 Mallory-weiss Syndrome 11 8.6 8.6 signal
227 Thrombocytopenia 958 8.5 8.9 signal
228 Lung Opacity 22 8.5 8.5 signal
229 Cholangitis 51 8.2 8.2 signal
230 Colitis 310 8.2 8.3 signal
231 Bone Marrow Failure 168 8.1 8.2 signal
232 Listeriosis 9 8.1 8.1 signal
233 Clostridium Colitis 10 8.1 8.1 signal
234 Metastases To Lung 94 8.1 8.1 signal
235 Prerenal Failure 11 7.8 7.8 signal
236 Subclavian Vein Thrombosis 9 7.8 7.8 signal
237 Leukopenia 390 7.7 7.9 signal
238 Autoimmune Hepatitis 54 7.7 7.7 signal
239 Arterial Thrombosis 15 7.6 7.6 signal
240 Dacryostenosis Acquired 10 7.6 7.6 signal
241 Restrictive Pulmonary Disease 9 7.6 7.6 signal
242 Transitional Cell Carcinoma 10 7.6 7.6 signal
243 Proteinuria 145 7.6 7.7 signal
244 Alanine Aminotransferase Abnormal 16 7.6 7.6 signal
245 Polyarthritis 40 7.5 7.6 signal
246 Metastases To Peritoneum 19 7.5 7.5 signal
247 Metastases To Liver 133 7.5 7.6 signal
248 Immune-mediated Myositis 20 7.5 7.5 signal
249 Neutropenia 1,027 7.5 7.8 signal
250 Hepatitis 190 7.3 7.4 signal
251 Escherichia Bacteraemia 17 7.3 7.3 signal
252 Blood Chloride Decreased 19 7.2 7.2 signal
253 Adrenocortical Insufficiency Acute 14 7.2 7.2 signal
254 Vascular Purpura 10 7.1 7.1 signal
255 Metastases To Lymph Nodes 48 7.1 7.1 signal
256 Anaemia Macrocytic 15 7.0 7.0 signal
257 Staphylococcus Test Positive 15 7.0 7.0 signal
258 Large Intestine Perforation 49 7.0 7.0 signal
259 Rash Maculo-papular 156 7.0 7.0 signal
260 Diabetes Insipidus 17 6.9 7.0 signal
261 Toxic Epidermal Necrolysis 105 6.9 6.9 signal
262 Peripheral Sensory Neuropathy 40 6.8 6.8 signal
263 Embolism 57 6.8 6.8 signal
264 Tumour Pain 9 6.7 6.7 signal
265 Ischaemia 31 6.6 6.6 signal
266 Anaemia 1,278 6.6 7.0 signal
267 Metastasis 48 6.6 6.6 signal
268 Panniculitis 16 6.6 6.6 signal
269 Aspartate Aminotransferase Abnormal 10 6.5 6.6 signal
270 Posterior Reversible Encephalopathy Syndrome 63 6.5 6.6 signal
271 Hyperphosphataemia 14 6.5 6.5 signal
272 Non-cardiac Chest Pain 21 6.5 6.5 signal
273 Vena Cava Thrombosis 11 6.5 6.5 signal
274 Hypomagnesaemia 91 6.5 6.5 signal
275 Pneumoperitoneum 12 6.5 6.5 signal
276 Inflammatory Marker Increased 32 6.5 6.5 signal
277 Empyema 13 6.4 6.5 signal
278 Metastases To Bone 106 6.4 6.4 signal
279 Peripheral Motor Neuropathy 9 6.4 6.4 signal
280 Periorbital Oedema 33 6.3 6.3 signal
281 Venous Thrombosis 25 6.3 6.3 signal
282 Chronic Inflammatory Demyelinating Polyradiculoneuropathy 9 6.3 6.3 signal
283 Mutism 9 6.2 6.2 signal
284 Polymyositis 11 6.2 6.2 signal
285 Duodenitis 19 6.1 6.1 signal
286 Cytopenia 74 6.1 6.1 signal
287 Pericardial Effusion 142 6.1 6.1 signal
288 Haemoptysis 171 6.0 6.1 signal
289 Hepatitis Toxic 16 6.0 6.0 signal
290 Thyroiditis 18 6.0 6.0 signal
291 Metastatic Neoplasm 26 6.0 6.0 signal
292 Keratitis 18 5.9 5.9 signal
293 Enterocolitis 34 5.9 5.9 signal
294 Duodenal Ulcer Haemorrhage 17 5.8 5.9 signal
295 Neoplasm Recurrence 20 5.8 5.8 signal
296 Hypocalcaemia 111 5.8 5.8 signal
297 Pleural Effusion 352 5.7 5.8 signal
298 Gastrointestinal Perforation 24 5.7 5.7 signal
299 Splenic Infarction 10 5.7 5.7 signal
300 Toxic Skin Eruption 58 5.7 5.7 signal
301 Hepatitis Acute 37 5.7 5.7 signal
302 Dermatitis Bullous 41 5.6 5.6 signal
303 Cytokine Release Syndrome 108 5.6 5.6 signal
304 Cardiac Tamponade 27 5.6 5.6 signal
305 Dysaesthesia 17 5.6 5.6 signal
306 Brain Natriuretic Peptide Increased 17 5.4 5.5 signal
307 Encephalitis 38 5.4 5.5 signal
308 Haemothorax 16 5.4 5.4 signal
309 Hypoproteinaemia 10 5.3 5.3 signal
310 Rheumatoid Nodule 15 5.3 5.3 signal
311 Capillary Leak Syndrome 11 5.3 5.3 signal
312 Acute Kidney Injury 808 5.2 5.4 signal
313 Intervertebral Discitis 10 5.2 5.2 signal
314 Neutrophil Count Decreased 214 5.2 5.3 signal
315 Mantle Cell Lymphoma 8 5.2 5.2 signal
316 Blood Thyroid Stimulating Hormone Decreased 24 5.2 5.2 signal
317 Atelectasis 51 5.2 5.2 signal
318 Granulocytopenia 30 5.2 5.2 signal
319 Traumatic Lung Injury 10 5.1 5.1 signal
320 Fungaemia 8 5.1 5.1 signal
321 Jugular Vein Thrombosis 9 5.0 5.0 signal
322 Septic Shock 218 5.0 5.0 signal
323 Bone Lesion 18 4.9 4.9 signal
324 Pneumothorax 79 4.9 4.9 signal
325 Neutrophil Count Abnormal 14 4.9 4.9 signal
326 Dermatitis Exfoliative Generalised 17 4.9 4.9 signal
327 Hiccups 40 4.8 4.8 signal
328 Hypokalaemia 225 4.8 4.9 signal
329 Pneumocystis Jirovecii Pneumonia 49 4.8 4.8 signal
330 Idiopathic Pulmonary Fibrosis 19 4.8 4.8 signal
331 General Physical Health Deterioration 560 4.8 4.9 signal
332 Pulmonary Haemorrhage 38 4.8 4.8 signal
333 Respiratory Failure 348 4.7 4.8 signal
334 Intestinal Ischaemia 26 4.7 4.7 signal
335 Cardiotoxicity 42 4.7 4.7 signal
336 Oral Fungal Infection 13 4.7 4.7 signal
337 Cachexia 24 4.6 4.6 signal
338 Hepatitis Cholestatic 28 4.6 4.6 signal
339 Pulmonary Embolism 441 4.6 4.6 signal
340 Pyelonephritis Acute 9 4.6 4.6 signal
341 Left Ventricular Dysfunction 30 4.4 4.4 signal
342 Polymyalgia Rheumatica 14 4.4 4.4 signal
343 Systemic Inflammatory Response Syndrome 17 4.4 4.4 signal
344 Cholestasis 85 4.4 4.4 signal
345 Transaminases Increased 98 4.4 4.4 signal
346 Erythema Multiforme 41 4.3 4.3 signal
347 Aplastic Anaemia 23 4.3 4.3 signal
348 Lichen Planus 10 4.3 4.3 signal
349 Vitiligo 10 4.3 4.3 signal
350 Ischaemic Stroke 77 4.3 4.3 signal
351 Polyneuropathy 51 4.2 4.2 signal
352 Urinary Tract Obstruction 10 4.2 4.2 signal
353 Haemolytic Anaemia 38 4.2 4.2 signal
354 Hepatic Lesion 18 4.1 4.1 signal
355 Escherichia Sepsis 12 4.1 4.1 signal
356 Dyspnoea At Rest 12 4.1 4.1 signal
357 Cutaneous Lupus Erythematosus 8 4.0 4.0 signal
358 Hepatic Function Abnormal 151 4.0 4.0 signal
359 Blood Creatinine Increased 266 4.0 4.0 signal
360 Agranulocytosis 75 4.0 4.0 signal
361 Blood Creatine Increased 18 4.0 4.0 signal
362 Blood Albumin Decreased 32 4.0 4.0 signal
363 Myositis 36 4.0 4.0 signal
364 Lip Oedema 17 4.0 4.0 signal
365 Infusion Related Reaction 262 3.9 3.9 signal
366 Thrombotic Thrombocytopenic Purpura 14 3.9 3.9 signal
367 Vasculitis 46 3.9 3.9 signal
368 Optic Ischaemic Neuropathy 14 3.9 3.9 signal
369 Drug Tolerance Decreased 11 3.9 3.9 signal
370 Intestinal Perforation 44 3.9 3.9 signal
371 Osteolysis 8 3.8 3.8 signal
372 Stomatitis 235 3.8 3.9 signal
373 Hyperpyrexia 16 3.8 3.8 signal
374 Drug-induced Liver Injury 119 3.8 3.8 signal
375 Tumour Haemorrhage 11 3.8 3.8 signal
376 Scleroderma 14 3.8 3.8 signal
377 Venous Thrombosis Limb 8 3.8 3.8 signal
378 Small Intestinal Obstruction 46 3.7 3.7 signal
379 Renal Impairment 311 3.7 3.7 signal
380 Cushingoid 12 3.7 3.7 signal
381 Lung Infiltration 33 3.7 3.7 signal
382 Renal Function Test Abnormal 17 3.7 3.7 signal
383 Atypical Pneumonia 11 3.6 3.6 signal
384 Drug Eruption 65 3.6 3.6 signal
385 Glomerulonephritis 9 3.6 3.6 signal
386 Peripheral Arterial Occlusive Disease 15 3.6 3.6 signal
387 Persecutory Delusion 9 3.6 3.6 signal
388 Aspartate Aminotransferase Increased 193 3.6 3.6 signal
389 Hyponatraemia 203 3.6 3.6 signal
390 Tachyarrhythmia 9 3.6 3.6 signal
391 Hepatocellular Injury 51 3.5 3.5 signal
392 Metastases To Spine 12 3.5 3.5 signal
393 Troponin Increased 27 3.5 3.5 signal
394 Dermatomyositis 9 3.5 3.5 signal
395 Hypophosphataemia 26 3.5 3.5 signal
396 Second Primary Malignancy 29 3.4 3.4 signal
397 Aplasia Pure Red Cell 12 3.4 3.4 signal
398 Tearfulness 15 3.4 3.4 signal
399 Cerebral Ischaemia 18 3.4 3.4 signal
400 Herpes Virus Infection 20 3.4 3.4 signal
401 Alanine Aminotransferase Increased 210 3.4 3.4 signal
402 Rash Pustular 25 3.4 3.4 signal
403 Pneumonia Bacterial 31 3.3 3.3 signal
404 Sudden Death 36 3.3 3.3 signal
405 Acute Respiratory Failure 64 3.3 3.3 signal
406 Bone Marrow Disorder 10 3.3 3.3 signal
407 Phlebitis 17 3.3 3.3 signal
408 Type Iv Hypersensitivity Reaction 9 3.3 3.3 signal
409 Electrolyte Imbalance 38 3.3 3.3 signal
410 C-reactive Protein Increased 120 3.3 3.3 signal
411 Platelet Count Decreased 350 3.2 3.3 signal
412 Compression Fracture 17 3.2 3.2 signal
413 Organising Pneumonia 16 3.2 3.2 signal
414 Brain Oedema 41 3.2 3.2 signal
415 Gamma-glutamyltransferase Increased 72 3.2 3.2 signal
416 Proctitis 9 3.2 3.2 signal
417 Pneumatosis Intestinalis 9 3.1 3.1 signal
418 Oesophageal Stenosis 9 3.1 3.1 signal
419 Immune Thrombocytopenic Purpura 9 3.1 3.1 signal
420 Ascites 92 3.1 3.1 signal
421 Mean Cell Volume Increased 8 3.1 3.1 signal
422 Cardiogenic Shock 44 3.0 3.0 signal
423 Sepsis 344 3.0 3.1 signal
424 Lumbar Vertebral Fracture 14 3.0 3.0 signal
425 Nephrotic Syndrome 21 3.0 3.0 signal
426 Thoracic Vertebral Fracture 9 3.0 3.0 signal
427 Purpura 27 3.0 3.0 signal
428 Odynophagia 18 3.0 3.0 signal
429 Disseminated Intravascular Coagulation 43 3.0 3.0 signal
430 Hypoxic-ischaemic Encephalopathy 8 3.0 3.0 signal
431 Lung Neoplasm 13 3.0 3.0 signal
432 Amylase Increased 11 3.0 3.0 signal
433 Creatinine Renal Clearance Decreased 12 2.9 2.9 signal
434 Faecaloma 16 2.9 2.9 signal
435 Hypovolaemic Shock 14 2.9 2.9 signal
436 Endocarditis 15 2.9 2.9 signal
437 Osteonecrosis Of Jaw 73 2.9 2.9 signal
438 Hypoxia 102 2.9 2.9 signal
439 Meningitis Aseptic 13 2.9 2.9 signal
440 Pulmonary Fibrosis 55 2.8 2.8 signal
441 Pleurisy 17 2.8 2.8 signal
442 Jaundice Cholestatic 10 2.8 2.8 signal
443 Blood Lactate Dehydrogenase Increased 45 2.8 2.8 signal
444 Neutrophilia 16 2.8 2.8 signal
445 Skin Erosion 9 2.8 2.8 signal
446 Blood Thyroid Stimulating Hormone Increased 26 2.8 2.8 signal
447 Pancreatic Carcinoma Metastatic 8 2.8 2.8 signal
448 Malnutrition 31 2.7 2.8 signal
449 Oesophageal Candidiasis 11 2.7 2.7 signal
450 Flank Pain 26 2.7 2.7 signal
451 Oral Candidiasis 36 2.7 2.7 signal
452 Emphysema 28 2.7 2.7 signal
453 Pericarditis 46 2.7 2.7 signal
454 Thrombocytosis 10 2.7 2.7 signal
455 Therapeutic Product Effect Incomplete 193 2.7 2.7 signal
456 Recurrent Cancer 11 2.7 2.7 signal
457 Mouth Ulceration 57 2.7 2.7 signal
458 Liver Injury 65 2.6 2.7 signal
459 Actinic Keratosis 7 2.6 2.6 signal
460 Blood Magnesium Decreased 23 2.6 2.6 signal
461 Tongue Ulceration 9 2.6 2.6 signal
462 Wound Dehiscence 9 2.6 2.6 signal
463 Dermatitis 55 2.6 2.6 signal
464 General Physical Condition Abnormal 18 2.6 2.6 signal
465 Varices Oesophageal 8 2.6 2.6 signal
466 Neurological Symptom 15 2.6 2.6 signal
467 Renal Failure 352 2.6 2.6 signal
468 Pulmonary Mass 39 2.6 2.6 signal
469 Decreased Appetite 607 2.6 2.6 signal
470 Atrial Flutter 21 2.6 2.6 signal
471 Chest X-ray Abnormal 8 2.5 2.5 signal
472 Respiratory Tract Infection 67 2.5 2.5 signal
473 Skin Abrasion 12 2.5 2.5 signal
474 Haematocrit Decreased 51 2.5 2.5 signal
475 Blood Urea Increased 43 2.5 2.5 signal
476 Epigastric Discomfort 10 2.5 2.5 signal
477 Acute Respiratory Distress Syndrome 45 2.5 2.5 signal
478 Arterial Occlusive Disease 20 2.5 2.5 signal
479 Sarcoidosis 12 2.5 2.5 signal
480 Ileus 31 2.5 2.5 signal
481 Oedema 136 2.5 2.5 signal
482 Pneumonia Viral 8 2.5 2.5 signal
483 Necrosis 14 2.5 2.5 signal
484 Blood Sodium Decreased 47 2.5 2.5 signal
485 Failure To Thrive 13 2.5 2.5 signal
486 Guillain-barre Syndrome 12 2.5 2.5 signal
487 Squamous Cell Carcinoma 23 2.4 2.4 signal
488 Stevens-johnson Syndrome 54 2.4 2.4 signal
489 Stress Cardiomyopathy 14 2.4 2.4 signal
490 Duodenal Ulcer 17 2.4 2.4 signal
491 Pneumonia 777 2.4 2.4 signal
492 Autoimmune Thyroiditis 9 2.4 2.4 signal
493 Protein Total Decreased 9 2.4 2.4 signal
494 Colitis Ischaemic 16 2.3 2.3 signal
495 Pathological Fracture 12 2.3 2.3 signal
496 Hepatic Cyst 8 2.3 2.3 signal
497 Aphthous Ulcer 18 2.3 2.3 signal
498 Circulatory Collapse 40 2.3 2.3 signal
499 Sudden Cardiac Death 8 2.3 2.3 signal
500 Blood Creatinine Abnormal 8 2.3 2.3 signal
501 Leukocytosis 42 2.3 2.3 signal
502 Pulmonary Alveolar Haemorrhage 13 2.3 2.3 signal
503 Lymphocyte Count Decreased 41 2.3 2.3 signal
504 Angiopathy 13 2.3 2.3 signal
505 Pemphigoid 17 2.3 2.3 signal
506 Type I Hypersensitivity 8 2.3 2.3 signal
507 Myasthenia Gravis 18 2.3 2.3 signal
508 Rash Vesicular 11 2.2 2.2 signal
509 Deep Vein Thrombosis 149 2.2 2.3 signal
510 White Blood Cell Count Decreased 246 2.2 2.2 signal
511 Myocardial Ischaemia 26 2.2 2.2 signal
512 Blood Uric Acid Increased 13 2.2 2.2 signal
513 Neurotoxicity 39 2.2 2.2 signal
514 Diarrhoea Haemorrhagic 21 2.2 2.2 signal
515 Cutaneous Vasculitis 8 2.2 2.2 signal
516 Neutrophil Count Increased 23 2.2 2.2 signal
517 Pancreatic Disorder 11 2.2 2.2 signal
518 Epistaxis 167 2.2 2.2 signal
519 Hypovolaemia 13 2.2 2.2 signal
520 Skin Reaction 31 2.2 2.2 signal
521 Polyuria 18 2.2 2.2 signal
522 Pancreatitis Acute 49 2.2 2.2 signal
523 Hyperuricaemia 9 2.2 2.2 signal
524 Cardiac Dysfunction 8 2.2 2.2 no signal
525 Gastrointestinal Inflammation 17 2.2 2.2 signal
526 Face Oedema 37 2.2 2.2 signal
527 Acute Myeloid Leukaemia 34 2.2 2.2 signal
528 Peritonitis 45 2.1 2.1 signal
529 Localised Oedema 10 2.1 2.1 signal
530 Platelet Count Abnormal 13 2.1 2.1 signal
531 Dyspnoea Exertional 80 2.1 2.1 signal
532 Folliculitis 22 2.1 2.1 signal
533 Bacteraemia 25 2.1 2.1 signal
534 Arteriosclerosis 20 2.1 2.1 signal
535 Ventricular Extrasystoles 22 2.1 2.1 signal
536 Dehydration 282 2.1 2.1 signal
537 Thyroid Disorder 32 2.0 2.0 signal
538 Bronchopulmonary Aspergillosis 16 2.0 2.0 signal
539 Abnormal Loss Of Weight 14 2.0 2.0 signal
540 Subarachnoid Haemorrhage 21 2.0 2.0 signal
541 Spinal Cord Compression 8 2.0 2.0 no signal
542 Adverse Reaction 27 2.0 2.0 signal
543 Acute Myocardial Infarction 60 2.0 2.0 no signal
544 Staphylococcal Sepsis 10 2.0 2.0 no signal
545 Liver Function Test Increased 43 2.0 2.0 no signal
546 Ataxia 24 2.0 2.0 no signal
547 Protein Urine Present 10 2.0 2.0 no signal
548 Blood Alkaline Phosphatase Increased 50 2.0 2.0 no signal
549 Periorbital Swelling 11 2.0 2.0 no signal
550 Aspergillus Infection 13 2.0 2.0 no signal
551 Haemodynamic Instability 15 2.0 2.0 no signal
552 Gastric Ulcer 38 2.0 2.0 no signal
553 Papilloedema 9 2.0 2.0 no signal
554 Skin Disorder 66 2.0 2.0 no signal
555 Hypophagia 50 1.9 1.9 no signal
556 Oedema Peripheral 241 1.9 2.0 no signal
557 Gastric Ulcer Haemorrhage 11 1.9 1.9 no signal
558 Cerebral Infarction 48 1.9 1.9 no signal
559 Diabetic Ketoacidosis 47 1.9 1.9 no signal
560 Cardiac Failure Acute 13 1.9 1.9 no signal
561 Anaphylactoid Reaction 8 1.9 1.9 no signal
562 Femoral Neck Fracture 10 1.9 1.9 no signal
563 Gastritis 51 1.9 1.9 no signal
564 Acute Generalised Exanthematous Pustulosis 15 1.9 1.9 no signal
565 Multiple Organ Dysfunction Syndrome 54 1.9 1.9 no signal
566 Spinal Osteoarthritis 17 1.9 1.9 no signal
567 Palmar-plantar Erythrodysaesthesia Syndrome 45 1.9 1.9 no signal
568 Respiratory Distress 53 1.9 1.9 no signal
569 Hepatic Failure 58 1.9 1.9 no signal
570 Cardiomyopathy 28 1.9 1.9 no signal
571 Pyrexia 654 1.9 1.9 no signal
572 Cardiac Failure Chronic 8 1.9 1.9 no signal
573 Hydronephrosis 14 1.8 1.8 no signal
574 Pulmonary Tuberculosis 8 1.8 1.8 no signal
575 Inappropriate Antidiuretic Hormone Secretion 19 1.8 1.8 no signal
576 Thrombotic Microangiopathy 18 1.8 1.8 no signal
577 Conjunctivitis 34 1.8 1.8 no signal
578 Lymphopenia 26 1.8 1.8 no signal
579 Lung Infection 29 1.8 1.8 no signal
580 Diverticulum Intestinal 8 1.8 1.8 no signal
581 Atrial Fibrillation 179 1.8 1.8 no signal
582 Haemoglobin Decreased 188 1.8 1.8 no signal
583 Multi-organ Failure 32 1.8 1.8 no signal
584 Fluid Intake Reduced 9 1.8 1.8 no signal
585 Body Temperature Decreased 18 1.8 1.8 no signal
586 Meningitis 12 1.8 1.8 no signal
587 Skin Infection 20 1.8 1.8 no signal
588 Clostridium Difficile Colitis 19 1.8 1.8 no signal
589 Anaphylactic Reaction 98 1.8 1.8 no signal
590 Dermatitis Exfoliative 9 1.8 1.8 no signal
591 Status Epilepticus 20 1.7 1.7 no signal
592 Ventricular Tachycardia 29 1.7 1.7 no signal
593 Lymphadenopathy 62 1.7 1.7 no signal
594 Hyperbilirubinaemia 18 1.7 1.7 no signal
595 Trismus 9 1.7 1.7 no signal
596 Lymphoedema 12 1.7 1.7 no signal
597 Blood Bilirubin Increased 47 1.7 1.7 no signal
598 Upper Gastrointestinal Haemorrhage 29 1.7 1.7 no signal
599 Carpal Tunnel Syndrome 24 1.7 1.7 no signal
600 Cardiac Failure 137 1.7 1.7 no signal
601 Nephropathy 16 1.7 1.7 no signal
602 Lipase Increased 13 1.7 1.7 no signal
603 Gingival Bleeding 23 1.7 1.7 no signal
604 Aortic Dissection 7 1.7 1.7 no signal
605 Melaena 37 1.7 1.7 no signal
606 Hemiplegia 14 1.7 1.7 no signal
607 Vomiting 786 1.7 1.7 no signal
608 Supraventricular Tachycardia 16 1.6 1.6 no signal
609 Asthenia 629 1.6 1.7 no signal
610 Diverticulitis 46 1.6 1.6 no signal
611 Liver Disorder 73 1.6 1.6 no signal
612 Petechiae 17 1.6 1.6 no signal
613 Skin Hyperpigmentation 14 1.6 1.6 no signal
614 Neuropathy Peripheral 154 1.6 1.6 no signal
615 Delirium 56 1.6 1.6 no signal
616 Hyperkalaemia 56 1.6 1.6 no signal
617 Onychoclasis 11 1.6 1.6 no signal
618 Shock Haemorrhagic 13 1.6 1.6 no signal
619 Covid-19 Pneumonia 19 1.6 1.6 no signal
620 Klebsiella Infection 8 1.6 1.6 no signal
621 Cyanosis 25 1.6 1.6 no signal
622 Dysphagia 150 1.6 1.6 no signal
623 Acute Coronary Syndrome 13 1.5 1.5 no signal
624 Diarrhoea 993 1.5 1.5 no signal
625 Disease Recurrence 73 1.5 1.5 no signal
626 Refusal Of Treatment By Patient 10 1.5 1.5 no signal
627 Pneumonia Aspiration 38 1.5 1.5 no signal
628 Hepatomegaly 15 1.5 1.5 no signal
629 Constipation 327 1.5 1.5 no signal
630 Renal Failure Acute 65 1.5 1.5 no signal
631 Blood Calcium Decreased 17 1.5 1.5 no signal
632 Red Blood Cell Count Decreased 43 1.5 1.5 no signal
633 Bronchiectasis 10 1.5 1.5 no signal
634 Lung Neoplasm Malignant 62 1.5 1.5 no signal
635 Blood Disorder 12 1.5 1.5 no signal
636 Nail Disorder 13 1.5 1.5 no signal
637 Orthostatic Hypotension 26 1.5 1.5 no signal
638 Platelet Count Increased 19 1.4 1.4 no signal
639 Cellulitis 73 1.4 1.4 no signal
640 Epilepsy 44 1.4 1.4 no signal
641 Rash 625 1.4 1.4 no signal
642 Acidosis 11 1.4 1.4 no signal
643 Hyperglycaemia 52 1.4 1.4 no signal
644 Encephalopathy 35 1.4 1.4 no signal
645 Intestinal Haemorrhage 8 1.4 1.4 no signal
646 White Blood Cell Count Abnormal 9 1.4 1.4 no signal
647 Hemiparesis 24 1.4 1.4 no signal
648 Anaphylactic Shock 36 1.4 1.4 no signal
649 C-reactive Protein Abnormal 9 1.4 1.4 no signal
650 Glomerular Filtration Rate Decreased 17 1.4 1.4 no signal
651 Bronchospasm 20 1.4 1.4 no signal
652 Appetite Disorder 9 1.4 1.4 no signal
653 Faeces Soft 10 1.4 1.4 no signal
654 Hypercalcaemia 17 1.4 1.4 no signal
655 Metabolic Disorder 8 1.4 1.4 no signal
656 Immune System Disorder 18 1.3 1.3 no signal
657 Arteriosclerosis Coronary Artery 9 1.3 1.3 no signal
658 Groin Pain 12 1.3 1.3 no signal
659 Gastrointestinal Disorder 120 1.3 1.3 no signal
660 Musculoskeletal Chest Pain 21 1.3 1.3 no signal
661 Respiratory Rate Increased 12 1.3 1.3 no signal
662 Lower Gastrointestinal Haemorrhage 10 1.3 1.3 no signal
663 Lupus-like Syndrome 12 1.3 1.3 no signal
664 Prothrombin Time Prolonged 8 1.3 1.3 no signal
665 Anal Fissure 7 1.3 1.3 no signal
666 Cognitive Disorder 61 1.3 1.3 no signal
667 Central Nervous System Lesion 18 1.3 1.3 no signal
668 Generalised Oedema 16 1.3 1.3 no signal
669 White Blood Cell Count Increased 50 1.3 1.3 no signal
670 Nausea 1,016 1.3 1.3 no signal
671 Ejection Fraction Decreased 20 1.3 1.3 no signal
672 Tachycardia 114 1.3 1.3 no signal
673 Eyelid Oedema 15 1.3 1.3 no signal
674 Spinal Pain 15 1.3 1.3 no signal
675 Sinus Tachycardia 18 1.2 1.2 no signal
676 Hypertension 269 1.2 1.3 no signal
677 Off Label Use 1,096 1.2 1.3 no signal
678 Cytomegalovirus Infection 21 1.2 1.2 no signal
679 Haematemesis 32 1.2 1.2 no signal
680 Ventricular Fibrillation 14 1.2 1.2 no signal
681 Renal Cyst 10 1.2 1.2 no signal
682 Therapy Non-responder 56 1.2 1.2 no signal
683 Toxicity To Various Agents 203 1.2 1.2 no signal
684 Dyspnoea 683 1.2 1.2 no signal
685 Infection 174 1.2 1.2 no signal
686 Atrioventricular Block Complete 8 1.2 1.2 no signal
687 Urosepsis 11 1.2 1.2 no signal
688 Product Use In Unapproved Indication 290 1.2 1.2 no signal
689 Skin Plaque 10 1.2 1.2 no signal
690 Drug Intolerance 114 1.2 1.2 no signal
691 Appendicitis 11 1.2 1.2 no signal
692 Oxygen Saturation Decreased 66 1.2 1.2 no signal
693 Cholecystitis 14 1.2 1.2 no signal
694 Hepatic Encephalopathy 11 1.2 1.2 no signal
695 Gastroenteritis 17 1.1 1.1 no signal
696 Papule 8 1.1 1.1 no signal
697 Chronic Obstructive Pulmonary Disease 60 1.1 1.1 no signal
698 Rash Pruritic 62 1.1 1.1 no signal
699 Nodule 15 1.1 1.1 no signal
700 Rebound Effect 13 1.1 1.1 no signal
701 Angina Pectoris 33 1.1 1.1 no signal
702 Lung Disorder 56 1.1 1.1 no signal
703 Skin Lesion 31 1.1 1.1 no signal
704 Renal Disorder 53 1.1 1.1 no signal
705 Neoplasm 13 1.1 1.1 no signal
706 Mental Status Changes 31 1.1 1.1 no signal
707 Hypotension 222 1.1 1.1 no signal
708 Haematuria 38 1.1 1.1 no signal
709 Aspiration 12 1.1 1.1 no signal
710 Tachypnoea 15 1.1 1.1 no signal
711 Acute Hepatic Failure 15 1.1 1.1 no signal
712 Treatment Failure 90 1.1 1.1 no signal
713 Cardio-respiratory Arrest 46 1.1 1.1 no signal
714 Cerebral Disorder 8 1.1 1.1 no signal
715 Rectal Haemorrhage 46 1.0 1.0 no signal
716 Pyelonephritis 9 1.0 1.0 no signal
717 Device Related Infection 16 1.0 1.0 no signal
718 Dysarthria 39 1.0 1.0 no signal
719 Myelodysplastic Syndrome 15 1.0 1.0 no signal
720 Sinus Bradycardia 10 1.0 1.0 no signal
721 Dysgeusia 77 1.0 1.0 no signal
722 Urine Output Decreased 9 1.0 1.0 no signal
723 Syncope 102 1.0 1.0 no signal
724 Immunodeficiency 15 1.0 1.0 no signal
725 Drug Interaction 161 1.0 1.0 no signal
726 Drug Toxicity 14 1.0 1.0 no signal
727 Ocular Discomfort 11 1.0 1.0 no signal
728 Myoclonus 12 1.0 1.0 no signal
729 Pancreatitis 53 1.0 1.0 no signal
730 Urinary Retention 33 1.0 1.0 no signal
731 Optic Neuritis 9 1.0 1.0 no signal
732 Oral Pain 22 1.0 1.0 no signal
733 Escherichia Infection 8 1.0 1.0 no signal
734 Generalised Tonic-clonic Seizure 16 1.0 1.0 no signal
735 Bone Pain 57 1.0 1.0 no signal
736 Progressive Multifocal Leukoencephalopathy 8 1.0 1.0 no signal
737 Candida Infection 16 0.9 0.9 no signal
738 Fatigue 739 0.9 0.9 no signal
739 Condition Aggravated 282 0.9 0.9 no signal
740 Chromaturia 21 0.9 0.9 no signal
741 Blood Potassium Increased 15 0.9 0.9 no signal
742 Back Injury 10 0.9 0.9 no signal
743 Liver Function Test Abnormal 27 0.9 0.9 no signal
744 Cough 257 0.9 0.9 no signal
745 Anorexia 12 0.9 0.9 no signal
746 Rash Erythematous 43 0.9 0.9 no signal
747 Cardiac Arrest 76 0.9 0.9 no signal
748 Thrombosis 74 0.9 0.9 no signal
749 Tumour Lysis Syndrome 8 0.9 0.9 no signal
750 Productive Cough 43 0.9 0.9 no signal
751 Lacrimation Increased 27 0.9 0.9 no signal
752 Gastrointestinal Haemorrhage 75 0.9 0.9 no signal
753 Death 768 0.9 0.9 no signal
754 Chronic Kidney Disease 68 0.9 0.9 no signal
755 Erythema 182 0.9 0.9 no signal
756 Diplopia 23 0.9 0.9 no signal
757 Eyelid Ptosis 9 0.9 0.9 no signal
758 Mitral Valve Incompetence 10 0.9 0.9 no signal
759 Scab 10 0.9 0.9 no signal
760 Prescribed Overdose 17 0.9 0.9 no signal
761 Shock 20 0.9 0.9 no signal
762 Muscle Atrophy 11 0.9 0.9 no signal
763 Tenderness 9 0.8 0.8 no signal
764 Drug Reaction With Eosinophilia And Systemic Symptoms 22 0.8 0.8 no signal
765 Blood Creatine Phosphokinase Increased 25 0.8 0.8 no signal
766 Abnormal Faeces 7 0.8 0.8 no signal
767 Coagulopathy 14 0.8 0.8 no signal
768 Diabetes Mellitus 64 0.8 0.8 no signal
769 Altered State Of Consciousness 18 0.8 0.8 no signal
770 Pulmonary Thrombosis 9 0.8 0.8 no signal
771 Abdominal Pain 190 0.8 0.8 no signal
772 Musculoskeletal Pain 43 0.8 0.8 no signal
773 Dysuria 30 0.8 0.8 no signal
774 Hepatic Steatosis 15 0.8 0.8 no signal
775 Hypertensive Crisis 9 0.8 0.8 no signal
776 Haemorrhage 84 0.8 0.8 no signal
777 Dermatitis Allergic 10 0.8 0.8 no signal
778 Muscular Weakness 91 0.8 0.8 no signal
779 Respiratory Disorder 24 0.8 0.8 no signal
780 Lower Respiratory Tract Infection 36 0.8 0.8 no signal
781 Motor Dysfunction 8 0.8 0.8 no signal
782 Inflammation 40 0.8 0.8 no signal
783 Electrocardiogram Qt Prolonged 28 0.8 0.8 no signal
784 Chest Pain 143 0.8 0.8 no signal
785 Dysphonia 45 0.8 0.8 no signal
786 Pulmonary Hypertension 16 0.8 0.8 no signal
787 Confusional State 123 0.7 0.7 no signal
788 Leukaemia 7 0.7 0.7 no signal
789 Muscle Tightness 12 0.7 0.7 no signal
790 Jaundice 20 0.7 0.7 no signal
791 Uveitis 10 0.7 0.7 no signal
792 Systemic Lupus Erythematosus 26 0.7 0.7 no signal
793 Blood Urine Present 14 0.7 0.7 no signal
794 Drug Ineffective 958 0.7 0.7 no signal
795 Coronary Artery Occlusion 10 0.7 0.7 no signal
796 Weight Decreased 202 0.7 0.7 no signal
797 Incorrect Route Of Product Administration 12 0.7 0.7 no signal
798 Pulmonary Oedema 32 0.7 0.7 no signal
799 Therapeutic Response Decreased 43 0.7 0.7 no signal
800 Presyncope 17 0.7 0.7 no signal
801 Angioedema 31 0.7 0.7 no signal
802 Bacterial Infection 13 0.7 0.7 no signal
803 Blood Potassium Decreased 21 0.7 0.7 no signal
804 Staphylococcal Infection 23 0.7 0.7 no signal
805 Covid-19 122 0.7 0.7 no signal
806 Eosinophilia 12 0.7 0.7 no signal
807 Splenomegaly 8 0.7 0.7 no signal
808 Rash Papular 15 0.7 0.7 no signal
809 Hyperlipidaemia 8 0.7 0.7 no signal
810 Drug Ineffective For Unapproved Indication 37 0.7 0.7 no signal
811 Coronary Artery Disease 20 0.6 0.6 no signal
812 Urinary Tract Infection 111 0.6 0.6 no signal
813 Breast Cancer Metastatic 7 0.6 0.6 no signal
814 Upper Respiratory Tract Infection 30 0.6 0.6 no signal
815 Deafness 17 0.6 0.6 no signal
816 Pharyngeal Oedema 10 0.6 0.6 no signal
817 Nervous System Disorder 20 0.6 0.6 no signal
818 Ulcer 10 0.6 0.6 no signal
819 Post Procedural Complication 12 0.6 0.6 no signal
820 Tuberculosis 8 0.6 0.6 no signal
821 Product Use Issue 116 0.6 0.6 no signal
822 Pulmonary Arterial Hypertension 9 0.6 0.6 no signal
823 Flushing 63 0.6 0.6 no signal
824 Depressed Level Of Consciousness 24 0.6 0.6 no signal
825 Osteoporosis 25 0.6 0.6 no signal
826 Vertigo 37 0.6 0.6 no signal
827 Cerebrovascular Accident 103 0.6 0.6 no signal
828 Gastric Haemorrhage 7 0.6 0.6 no signal
829 Fungal Infection 20 0.6 0.6 no signal
830 Renal Injury 18 0.6 0.6 no signal
831 Haematochezia 33 0.6 0.6 no signal
832 Taste Disorder 12 0.6 0.6 no signal
833 Bone Disorder 11 0.6 0.6 no signal
834 Seizure 68 0.6 0.6 no signal
835 Hepatic Enzyme Increased 40 0.6 0.6 no signal
836 Myalgia 100 0.6 0.6 no signal
837 Chest Discomfort 60 0.6 0.6 no signal
838 Body Temperature Increased 12 0.6 0.6 no signal
839 Delusion 9 0.6 0.6 no signal
840 Skin Ulcer 15 0.6 0.6 no signal
841 Cholelithiasis 19 0.6 0.6 no signal
842 Neuralgia 14 0.6 0.6 no signal
843 Device Occlusion 8 0.6 0.6 no signal
844 Drug Effect Incomplete 21 0.6 0.6 no signal
845 Arrhythmia 27 0.6 0.6 no signal
846 Aphasia 17 0.6 0.6 no signal
847 Oropharyngeal Pain 51 0.5 0.5 no signal
848 Hypersensitivity 102 0.5 0.5 no signal
849 Inappropriate Schedule Of Product Administration 97 0.5 0.5 no signal
850 Retinal Detachment 5 0.5 0.5 no signal
851 Drug Level Increased 9 0.5 0.5 no signal
852 Incorrect Product Administration Duration 11 0.5 0.5 no signal
853 Metabolic Acidosis 17 0.5 0.5 no signal
854 Intentional Product Use Issue 47 0.5 0.5 no signal
855 Intestinal Obstruction 20 0.5 0.5 no signal
856 Pain In Jaw 15 0.5 0.5 no signal
857 Musculoskeletal Discomfort 9 0.5 0.5 no signal
858 Ageusia 13 0.5 0.5 no signal
859 Retching 11 0.5 0.5 no signal
860 Post Procedural Haemorrhage 6 0.5 0.5 no signal
861 Blood Pressure Decreased 34 0.5 0.5 no signal
862 Abdominal Pain Lower 13 0.5 0.5 no signal
863 Viral Infection 17 0.5 0.5 no signal
864 Laboratory Test Abnormal 15 0.5 0.5 no signal
865 Pruritus 192 0.5 0.5 no signal
866 Back Pain 118 0.5 0.5 no signal
867 Unresponsive To Stimuli 13 0.5 0.5 no signal
868 Thirst 9 0.5 0.5 no signal
869 Spinal Fracture 10 0.5 0.5 no signal
870 Haematoma 13 0.5 0.5 no signal
871 Mass 7 0.5 0.5 no signal
872 Malaise 219 0.5 0.5 no signal
873 Flatulence 28 0.5 0.5 no signal
874 Hypothermia 5 0.5 0.5 no signal
875 Myocardial Infarction 86 0.5 0.5 no signal
876 Alopecia 96 0.5 0.5 no signal
877 Paraesthesia Oral 7 0.5 0.5 no signal
878 International Normalised Ratio Increased 14 0.5 0.5 no signal
879 Eczema 24 0.5 0.5 no signal
880 Cerebral Haemorrhage 17 0.5 0.5 no signal
881 Full Blood Count Abnormal 5 0.5 0.5 no signal
882 Urinary Incontinence 14 0.5 0.5 no signal
883 Sleep Apnoea Syndrome 9 0.5 0.5 no signal
884 Paraesthesia 74 0.5 0.5 no signal
885 Blindness 19 0.5 0.5 no signal
886 Restlessness 17 0.5 0.5 no signal
887 Laryngitis 5 0.5 0.5 no signal
888 Herpes Zoster 26 0.4 0.4 no signal
889 Obstructive Airways Disorder 5 0.4 0.4 no signal
890 Dizziness 222 0.4 0.4 no signal
891 Skin Exfoliation 37 0.4 0.4 no signal
892 Product Prescribing Issue 9 0.4 0.4 no signal
893 Abscess 7 0.4 0.4 no signal
894 Chills 51 0.4 0.4 no signal
895 Blood Glucose Abnormal 8 0.4 0.4 no signal
896 Adverse Event 39 0.4 0.4 no signal
897 Poor Quality Sleep 9 0.4 0.4 no signal
898 Joint Stiffness 11 0.4 0.4 no signal
899 Hypoacusis 18 0.4 0.4 no signal
900 Arthritis 33 0.4 0.4 no signal
901 Subdural Haematoma 6 0.4 0.4 no signal
902 Clostridium Difficile Infection 9 0.4 0.4 no signal
903 Type 2 Diabetes Mellitus 14 0.4 0.4 no signal
904 Abdominal Pain Upper 85 0.4 0.4 no signal
905 Apathy 6 0.4 0.4 no signal
906 Drug Effective For Unapproved Indication 12 0.4 0.4 no signal
907 Neoplasm Malignant 27 0.4 0.4 no signal
908 Bronchitis 30 0.4 0.4 no signal
909 Respiratory Arrest 11 0.4 0.4 no signal
910 Hip Arthroplasty 6 0.4 0.4 no signal
911 Blood Triglycerides Increased 7 0.4 0.4 no signal
912 Wheezing 23 0.4 0.4 no signal
913 Abdominal Distension 40 0.4 0.4 no signal
914 Transient Ischaemic Attack 13 0.4 0.4 no signal
915 Coma 18 0.4 0.4 no signal
916 Neck Pain 21 0.4 0.4 no signal
917 Breast Pain 4 0.4 0.4 no signal
918 Sopor 5 0.4 0.4 no signal
919 Malignant Melanoma 5 0.4 0.4 no signal
920 Dry Mouth 30 0.4 0.4 no signal
921 Fracture 7 0.4 0.4 no signal
922 Tinnitus 17 0.4 0.4 no signal
923 Faeces Discoloured 8 0.4 0.4 no signal
924 Adverse Drug Reaction 33 0.4 0.4 no signal
925 Impaired Healing 12 0.4 0.4 no signal
926 Dry Skin 48 0.4 0.4 no signal
927 Colitis Ulcerative 16 0.4 0.4 no signal
928 Bradycardia 19 0.4 0.4 no signal
929 Somnolence 71 0.3 0.3 no signal
930 Erectile Dysfunction 9 0.3 0.3 no signal
931 Full Blood Count Decreased 7 0.3 0.3 no signal
932 Ocular Hyperaemia 16 0.3 0.3 no signal
933 Rhinorrhoea 22 0.3 0.3 no signal
934 Dysstasia 10 0.3 0.3 no signal
935 Arthralgia 141 0.3 0.3 no signal
936 Pain 208 0.3 0.3 no signal
937 Fluid Retention 17 0.3 0.3 no signal
938 Hypoglycaemia 16 0.3 0.3 no signal
939 Hepatitis C 4 0.3 0.3 no signal
940 Disorientation 13 0.3 0.3 no signal
941 Skin Discolouration 15 0.3 0.3 no signal
942 Brain Neoplasm 3 0.3 0.3 no signal
943 Blister 18 0.3 0.3 no signal
944 Ill-defined Disorder 19 0.3 0.3 no signal
945 Rhabdomyolysis 13 0.3 0.3 no signal
946 Palpitations 36 0.3 0.3 no signal
947 Swelling Face 20 0.3 0.3 no signal
948 Loss Of Consciousness 39 0.3 0.3 no signal
949 Influenza 34 0.3 0.3 no signal
950 Headache 190 0.3 0.3 no signal
951 Pallor 8 0.3 0.3 no signal
952 Visual Impairment 36 0.3 0.3 no signal
953 Movement Disorder 9 0.3 0.3 no signal
954 Balance Disorder 24 0.3 0.3 no signal
955 Convulsion 16 0.3 0.3 no signal
956 Cardiovascular Disorder 7 0.3 0.3 no signal
957 Osteonecrosis 9 0.3 0.3 no signal
958 Lip Swelling 9 0.3 0.3 no signal
959 Fistula 3 0.3 0.3 no signal
960 Fall 88 0.3 0.3 no signal
961 Lethargy 15 0.3 0.3 no signal
962 Rash Macular 9 0.3 0.3 no signal
963 Femur Fracture 8 0.3 0.3 no signal
964 Dyspepsia 25 0.3 0.2 no signal
965 Blood Glucose Increased 48 0.2 0.2 no signal
966 Premature Delivery 4 0.2 0.2 no signal
967 Hyperhidrosis 32 0.2 0.2 no signal
968 Speech Disorder 13 0.2 0.2 no signal
969 Rheumatoid Arthritis 28 0.2 0.2 no signal
970 Drug Hypersensitivity 48 0.2 0.2 no signal
971 Depressed Mood 13 0.2 0.2 no signal
972 Vision Blurred 33 0.2 0.2 no signal
973 Pemphigus 3 0.2 0.2 no signal
974 Joint Swelling 29 0.2 0.2 no signal
975 Visual Acuity Reduced 8 0.2 0.2 no signal
976 Mobility Decreased 17 0.2 0.2 no signal
977 Gastrooesophageal Reflux Disease 19 0.2 0.2 no signal
978 Feeling Hot 14 0.2 0.2 no signal
979 Pain In Extremity 66 0.2 0.2 no signal
980 Cardiac Failure Congestive 18 0.2 0.2 no signal
981 Disturbance In Attention 12 0.2 0.2 no signal
982 Akathisia 3 0.2 0.2 no signal
983 Nephrolithiasis 10 0.2 0.2 no signal
984 Blood Pressure Increased 33 0.2 0.2 no signal
985 Gait Disturbance 41 0.2 0.2 no signal
986 Hot Flush 16 0.2 0.2 no signal
987 Urticaria 35 0.2 0.2 no signal
988 Loss Of Personal Independence In Daily Activities 10 0.2 0.2 no signal
989 Insomnia 56 0.2 0.2 no signal
990 Agitation 15 0.2 0.2 no signal
991 Anxiety 58 0.2 0.2 no signal
992 Treatment Noncompliance 11 0.2 0.2 no signal
993 Weight Increased 45 0.2 0.2 no signal
994 Depression 46 0.2 0.2 no signal
995 Discomfort 12 0.2 0.2 no signal
996 Skin Burning Sensation 14 0.2 0.2 no signal
997 Heart Rate Increased 19 0.2 0.2 no signal
998 Hypoaesthesia 28 0.2 0.2 no signal
999 Arthropathy 10 0.2 0.2 no signal
1000 Peripheral Swelling 27 0.2 0.2 no signal
1001 Vaginal Haemorrhage 7 0.2 0.2 no signal
1002 Acne 12 0.2 0.2 no signal
1003 Influenza Like Illness 13 0.2 0.2 no signal
1004 Sleep Disorder 11 0.2 0.2 no signal
1005 Psoriasis 20 0.2 0.1 no signal
1006 Contusion 14 0.1 0.1 no signal
1007 Nasopharyngitis 26 0.1 0.1 no signal
1008 Cataract 8 0.1 0.1 no signal
1009 Gynaecomastia 4 0.1 0.1 no signal
1010 Abdominal Discomfort 21 0.1 0.1 no signal
1011 Hallucination 9 0.1 0.1 no signal
1012 Overdose 26 0.1 0.1 no signal
1013 Cardiac Disorder 11 0.1 0.1 no signal
1014 Tremor 19 0.1 0.1 no signal
1015 Hospitalisation 17 0.1 0.1 no signal
1016 Sinusitis 11 0.1 0.1 no signal
1017 Intentional Product Misuse 9 0.1 0.1 no signal
1018 Musculoskeletal Stiffness 9 0.1 0.1 no signal
1019 Incorrect Dose Administered 23 0.1 0.1 no signal
1020 No Adverse Event 16 0.1 0.1 no signal
1021 Dependence 5 0.1 0.1 no signal
1022 Feeling Abnormal 20 0.1 0.1 no signal
1023 Asthma 9 0.1 0.1 no signal
1024 Emotional Distress 9 0.1 0.1 no signal
1025 Muscle Spasms 13 0.1 0.1 no signal
1026 Memory Impairment 9 0.1 0.1 no signal
1027 Product Dose Omission Issue 17 0.1 0.1 no signal
1028 Bladder Cancer 3 0.0 0.0 no signal