Drug

Penicillamine

31 flagged reaction(s) · 1,272 total co-reports · max PRR 138.1

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Red Blood Cell Sedimentation Rate Increased	67	138.1	148.8	signal
2	Vasculitis	52	101.8	107.8	signal
3	Proteinuria	65	78.6	84.5	signal
4	Cardiovascular Disorder	67	59.7	64.2	signal
5	Inflammation	111	49.2	55.8	signal
6	Contraindicated Product Administered	62	46.8	50.1	signal
7	Anaphylactic Reaction	77	31.9	34.7	signal
8	Joint Swelling	144	27.2	32.0	signal
9	Petechiae	11	24.0	24.3	signal
10	Drug Hypersensitivity	180	21.1	25.9	signal
11	Treatment Failure	69	19.1	20.6	signal
12	Drug Intolerance	79	18.7	20.3	signal
13	Pulmonary Fibrosis	15	17.8	18.1	signal
14	Pain In Jaw	15	12.0	12.2	signal
15	Cytopenia	6	11.4	11.5	signal
16	Dermatitis	10	11.0	11.1	signal
17	Musculoskeletal Stiffness	42	10.9	11.4	signal
18	Rheumatoid Arthritis	53	10.7	11.2	signal
19	Adverse Reaction	6	10.3	10.3	signal
20	Bone Disorder	8	9.9	10.0	signal
21	Metastases To Lung	5	9.8	9.9	signal
22	Urticaria	71	9.7	10.4	signal
23	Dystonia	8	9.3	9.4	signal
24	Parkinsonism	4	9.3	9.4	signal
25	Decreased Immune Responsiveness	4	9.3	9.3	signal
26	Drug Exposure During Pregnancy	14	9.2	9.3	signal
27	Stevens-johnson Syndrome	9	9.2	9.3	signal
28	Inability To Afford Medication	3	6.9	7.0	signal
29	Cytomegalovirus Infection	5	6.8	6.9	signal
30	Anorexia	3	5.2	5.2	signal
31	Myelosuppression	7	4.7	4.7	signal