OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pertuzumab

1,097 flagged reaction(s) · 94,523 total co-reports · max PRR 362.2
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Her2 Positive Breast Cancer 117 362.2 363.8 signal
2 Hyperfibrinogenaemia 13 184.1 184.2 signal
3 Lacrimal Structure Injury 59 143.7 144.0 signal
4 Her-2 Positive Breast Cancer 21 133.8 133.9 signal
5 Nail Bed Inflammation 46 131.2 131.5 signal
6 Delusion Of Grandeur 63 127.1 127.4 signal
7 Nail Toxicity 38 113.5 113.7 signal
8 Sarcoid-like Reaction 23 85.4 85.4 signal
9 Nail Dystrophy 48 73.4 73.5 signal
10 Vascular Fragility 12 66.0 66.0 signal
11 Vessel Puncture Site Bruise 14 59.1 59.2 signal
12 Pseudocirrhosis 22 55.7 55.7 signal
13 Nasal Mucosal Disorder 39 55.4 55.5 signal
14 Bone Marrow Infiltration 24 51.4 51.4 signal
15 Microvascular Coronary Artery Disease 13 51.2 51.3 signal
16 Dacryostenosis Acquired 77 48.9 49.1 signal
17 Granulomatous Lymphadenitis 11 48.9 48.9 signal
18 Metastases To Soft Tissue 15 47.2 47.2 signal
19 Metastases To Skin 58 46.5 46.6 signal
20 Central Vision Loss 11 41.6 41.7 signal
21 Metastases To Central Nervous System 641 40.8 41.8 signal
22 Pneumonitis Chemical 17 39.3 39.3 signal
23 Alopecia Totalis 16 39.2 39.2 signal
24 Streptococcal Sepsis 57 38.9 39.0 signal
25 Biliary Sepsis 22 38.8 38.8 signal
26 Radiation Skin Injury 55 38.5 38.6 signal
27 Breast Neoplasm 48 37.9 37.9 signal
28 Ejection Fraction Decreased 717 37.4 38.4 signal
29 Lymphocyte Count Abnormal 52 37.4 37.5 signal
30 Metastases To Breast 15 37.2 37.3 signal
31 Myelosuppression 1,555 37.1 39.3 signal
32 Gastroenteritis Radiation 15 36.9 36.9 signal
33 Catheter Site Bruise 13 36.3 36.3 signal
34 Breast Cancer Recurrent 138 35.5 35.7 signal
35 Mastectomy 75 34.8 34.9 signal
36 Radiation Necrosis 24 34.1 34.1 signal
37 Recall Phenomenon 35 33.9 33.9 signal
38 Hyperproteinaemia 11 33.4 33.4 signal
39 Meibomian Gland Dysfunction 18 33.0 33.0 signal
40 Nodular Regenerative Hyperplasia 29 32.9 33.0 signal
41 Hair Disorder 336 32.6 33.0 signal
42 Breast Operation 32 31.7 31.8 signal
43 Vascular Device Infection 175 31.2 31.4 signal
44 Onycholysis 59 30.6 30.7 signal
45 Cardiotoxicity 335 30.4 30.8 signal
46 Breast Cancer Metastatic 402 30.2 30.6 signal
47 Mean Platelet Volume Decreased 31 30.0 30.1 signal
48 Polyneuropathy 440 29.8 30.2 signal
49 Cardiac Dysfunction 134 29.5 29.6 signal
50 Dilated Cardiomyopathy 34 29.4 29.5 signal
51 Hand Dermatitis 24 29.3 29.3 signal
52 Left Ventricular Dysfunction 241 29.1 29.3 signal
53 Breast Inflammation 11 29.0 29.0 signal
54 Breast Cellulitis 11 27.9 27.9 signal
55 Metastases To Chest Wall 12 27.8 27.8 signal
56 Acute Interstitial Pneumonitis 18 27.6 27.6 signal
57 Tumour Pain 45 27.3 27.3 signal
58 Madarosis 389 26.6 27.0 signal
59 Carbohydrate Antigen 15-3 Increased 25 26.3 26.3 signal
60 Aortitis 22 25.8 25.9 signal
61 Nail Bed Bleeding 18 25.4 25.5 signal
62 Hair Colour Changes 396 25.2 25.6 signal
63 Enterocolitis Infectious 29 24.9 25.0 signal
64 Breast Disorder 62 24.2 24.3 signal
65 Pseudomonal Sepsis 53 24.0 24.1 signal
66 Nail Infection 43 24.0 24.0 signal
67 Vaginal Prolapse 13 24.0 24.0 signal
68 Metastases To Bone Marrow 15 23.8 23.8 signal
69 Hair Texture Abnormal 396 23.4 23.8 signal
70 Tonsillar Disorder 33 23.3 23.3 signal
71 Metastases To Meninges 65 23.1 23.2 signal
72 Folate Deficiency 33 23.0 23.0 signal
73 Alopecia Areata 50 22.7 22.8 signal
74 Metastases To Lymph Nodes 190 22.6 22.8 signal
75 Mastitis 52 22.0 22.0 signal
76 Peripheral Sensory Neuropathy 160 21.8 21.9 signal
77 Hemianopia 27 21.5 21.5 signal
78 Metastases To The Mediastinum 11 21.1 21.1 signal
79 Dental Fistula 11 20.9 20.9 signal
80 Ventricular Dysfunction 68 20.8 20.9 signal
81 Post-traumatic Pain 12 20.8 20.8 signal
82 Intercepted Product Storage Error 89 20.7 20.8 signal
83 Cystitis Noninfective 34 20.2 20.2 signal
84 Granulocyte Count Decreased 45 20.1 20.1 signal
85 Intercepted Medication Error 118 20.1 20.1 signal
86 Onychalgia 25 19.9 19.9 signal
87 Paronychia 102 18.7 18.8 signal
88 Seroma 30 18.7 18.7 signal
89 Invasive Ductal Breast Carcinoma 64 18.7 18.7 signal
90 Breast Conserving Surgery 12 18.6 18.6 signal
91 Metastases To Pleura 24 18.3 18.3 signal
92 Metastases To Lung 262 18.0 18.2 signal
93 Vasogenic Cerebral Oedema 16 17.9 17.9 signal
94 Psychological Trauma 195 17.7 17.8 signal
95 Left Ventricular Dilatation 11 17.4 17.4 signal
96 Neutropenic Sepsis 155 17.2 17.2 signal
97 Lymphoedema 148 17.0 17.1 signal
98 Hypermetabolism 11 16.6 16.6 signal
99 Eastern Cooperative Oncology Group Performance Status Worsened 26 16.6 16.6 signal
100 Systolic Dysfunction 22 16.5 16.5 signal
101 Autonomic Neuropathy 21 16.4 16.4 signal
102 Metastasis 148 16.3 16.4 signal
103 Rhinalgia 56 16.2 16.2 signal
104 Osteosclerosis 32 16.0 16.1 signal
105 Mucosal Inflammation 528 16.0 16.3 signal
106 Lymphangiosis Carcinomatosa 21 15.9 15.9 signal
107 Excessive Eye Blinking 29 15.5 15.5 signal
108 Hypermagnesaemia 12 14.8 14.8 signal
109 Peripheral Sensorimotor Neuropathy 23 14.7 14.7 signal
110 Mucosal Dryness 37 14.6 14.6 signal
111 Hyperpyrexia 76 14.5 14.5 signal
112 B-cell Type Acute Leukaemia 13 14.3 14.3 signal
113 Palmar Erythema 20 13.8 13.8 signal
114 Erysipelas 88 13.7 13.8 signal
115 Skin Toxicity 97 13.7 13.8 signal
116 Red Cell Distribution Width Increased 72 13.7 13.7 signal
117 Metastases To Bone 276 13.3 13.4 signal
118 Systemic Scleroderma 12 13.1 13.2 signal
119 Osteochondrosis 19 12.8 12.8 signal
120 Intraductal Proliferative Breast Lesion 20 12.5 12.5 signal
121 Metastases To Liver 277 12.4 12.6 signal
122 Metastatic Neoplasm 67 12.2 12.3 signal
123 Dermatitis Acneiform 92 12.0 12.0 signal
124 Atrophic Vulvovaginitis 11 11.9 11.9 signal
125 Perforation 12 11.9 11.9 signal
126 Pulmonary Hypoplasia 12 11.9 11.9 signal
127 Nail Discolouration 59 11.9 11.9 signal
128 Vulvovaginal Candidiasis 20 11.8 11.8 signal
129 Axillary Pain 22 11.7 11.7 signal
130 Ejection Fraction Abnormal 18 11.5 11.5 signal
131 Nail Disorder 126 11.4 11.4 signal
132 Oropharyngeal Candidiasis 13 11.3 11.3 signal
133 Nasal Ulcer 23 11.3 11.3 signal
134 Metastases To Adrenals 13 11.1 11.1 signal
135 Recurrent Cancer 57 11.1 11.1 signal
136 Soft Tissue Infection 25 10.8 10.8 signal
137 Onychomadesis 56 10.6 10.6 signal
138 Metastases To Spine 45 10.5 10.6 signal
139 Duodenal Perforation 13 10.5 10.5 signal
140 Large Intestine Infection 16 10.4 10.4 signal
141 Mucosal Disorder 13 10.3 10.3 signal
142 Gastrointestinal Toxicity 61 10.2 10.2 signal
143 Cystitis Haemorrhagic 52 10.2 10.2 signal
144 Radiation Pneumonitis 27 9.9 9.9 signal
145 Catheter Site Pain 32 9.9 9.9 signal
146 Nasal Disorder 33 9.7 9.7 signal
147 Right Ventricular Dysfunction 13 9.5 9.5 signal
148 Pituitary Tumour 18 9.4 9.4 signal
149 Jugular Vein Thrombosis 21 9.3 9.3 signal
150 Neuropathy Peripheral 1,123 9.3 9.7 signal
151 Cardiac Ventricular Thrombosis 15 9.3 9.3 signal
152 Palmar-plantar Erythrodysaesthesia Syndrome 274 9.2 9.3 signal
153 Osteolysis 24 9.2 9.2 signal
154 Intracranial Mass 11 9.2 9.2 signal
155 Blood Magnesium Decreased 100 9.1 9.1 signal
156 Megacolon 18 9.0 9.0 signal
157 Hypersensitivity Pneumonitis 13 9.0 9.0 signal
158 Neurological Decompensation 26 9.0 9.0 signal
159 Subclavian Vein Thrombosis 13 8.9 8.9 signal
160 Febrile Neutropenia 752 8.9 9.1 signal
161 Disease Progression 1,336 8.9 9.3 signal
162 Myocardial Injury 11 8.7 8.7 signal
163 Blood Pressure Diastolic Decreased 81 8.6 8.6 signal
164 Blood Pressure Systolic Decreased 49 8.5 8.5 signal
165 Onychoclasis 74 8.4 8.5 signal
166 Peripheral Motor Neuropathy 15 8.4 8.4 signal
167 Capillary Leak Syndrome 22 8.4 8.4 signal
168 Hyperaemia 21 8.3 8.3 signal
169 Hepatic Lesion 45 8.2 8.2 signal
170 Keratitis 31 8.0 8.0 signal
171 Hypertransaminasaemia 69 7.9 7.9 signal
172 Blood Pressure Diastolic Abnormal 26 7.9 7.9 signal
173 Malignant Pleural Effusion 17 7.9 7.9 signal
174 Paraparesis 18 7.9 7.9 signal
175 Cardiomyopathy 149 7.9 7.9 signal
176 Electric Shock Sensation 27 7.9 7.9 signal
177 Neutrophil Count Increased 103 7.8 7.9 signal
178 Escherichia Test Positive 12 7.8 7.8 signal
179 Vulvovaginal Dryness 32 7.8 7.8 signal
180 Dyschezia 30 7.8 7.8 signal
181 Ventricular Hypokinesia 32 7.8 7.8 signal
182 Tongue Coated 17 7.7 7.7 signal
183 Oligohydramnios 33 7.7 7.7 signal
184 Pneumonitis 266 7.7 7.8 signal
185 Alveolitis 14 7.7 7.7 signal
186 Tumour Marker Increased 47 7.6 7.7 signal
187 Hypothalamo-pituitary Disorder 14 7.6 7.6 signal
188 Gastrointestinal Bacterial Infection 11 7.5 7.5 signal
189 Dysaesthesia 29 7.5 7.5 signal
190 Neoplasm Recurrence 32 7.4 7.4 signal
191 Device Related Sepsis 19 7.3 7.3 signal
192 Therapy Partial Responder 140 7.3 7.3 signal
193 Neutrophil Count Decreased 375 7.2 7.3 signal
194 Blood Creatine Increased 41 7.2 7.2 signal
195 Lymphocyte Count Decreased 161 7.1 7.2 signal
196 Catheter Site Erythema 19 7.1 7.1 signal
197 Hypokalaemia 408 7.0 7.0 signal
198 Varicose Vein 46 6.9 6.9 signal
199 Haematotoxicity 82 6.9 6.9 signal
200 Stress Cardiomyopathy 50 6.8 6.8 signal
201 Blood Creatinine Decreased 27 6.7 6.7 signal
202 Device Related Infection 132 6.7 6.7 signal
203 Affective Disorder 67 6.7 6.7 signal
204 Mean Cell Haemoglobin Increased 14 6.6 6.6 signal
205 Craniocerebral Injury 25 6.5 6.5 signal
206 Dermatomyositis 21 6.5 6.5 signal
207 Dysentery 15 6.3 6.3 signal
208 Bacterial Test Positive 18 6.3 6.3 signal
209 Alopecia 1,569 6.2 6.6 signal
210 Odynophagia 47 6.2 6.2 signal
211 Subacute Cutaneous Lupus Erythematosus 14 6.2 6.2 signal
212 Mucous Membrane Disorder 11 6.2 6.2 signal
213 Abdominal Rigidity 21 6.1 6.1 signal
214 Vascular Rupture 12 6.0 6.0 signal
215 Atrial Thrombosis 16 6.0 6.0 signal
216 Hypomagnesaemia 106 6.0 6.0 signal
217 Pleuritic Pain 21 5.9 5.9 signal
218 Stomatitis 457 5.9 6.0 signal
219 Breast Pain 80 5.9 5.9 signal
220 Coccydynia 11 5.9 5.9 signal
221 Neutropenia 1,006 5.8 6.0 signal
222 Neurotoxicity 129 5.8 5.8 signal
223 Monocyte Count Increased 27 5.8 5.8 signal
224 Acute Leukaemia 12 5.8 5.8 signal
225 Enterocolitis 42 5.7 5.7 signal
226 Lacrimation Increased 219 5.7 5.8 signal
227 Papilloedema 33 5.7 5.7 signal
228 Interstitial Lung Disease 351 5.7 5.7 signal
229 Dyspnoea At Rest 21 5.7 5.7 signal
230 Carcinoembryonic Antigen Increased 14 5.7 5.7 signal
231 Neoplasm Progression 254 5.6 5.7 signal
232 Tenosynovitis 20 5.6 5.6 signal
233 Bone Lesion 26 5.6 5.6 signal
234 Portal Hypertension 22 5.6 5.6 signal
235 Intracranial Pressure Increased 38 5.3 5.3 signal
236 Diastolic Dysfunction 21 5.3 5.3 signal
237 Breast Mass 45 5.2 5.2 signal
238 Brain Oedema 84 5.2 5.2 signal
239 Painful Respiration 16 5.2 5.2 signal
240 Infusion Related Reaction 438 5.2 5.2 signal
241 Pulmonary Mass 98 5.1 5.2 signal
242 Catheter Site Haemorrhage 16 5.1 5.1 signal
243 Blood Pressure Systolic Abnormal 16 5.0 5.0 signal
244 Lymphadenopathy Mediastinal 12 4.9 4.9 signal
245 Brain Neoplasm 58 4.9 4.9 signal
246 Vulvovaginal Pain 30 4.9 4.9 signal
247 Mitral Valve Incompetence 71 4.9 4.9 signal
248 Embolism Venous 19 4.9 4.9 signal
249 Urinary Tract Disorder 28 4.9 4.9 signal
250 Tongue Ulceration 21 4.8 4.8 signal
251 Skin Infection 69 4.8 4.8 signal
252 Hyperaesthesia 51 4.8 4.8 signal
253 Leukopenia 304 4.8 4.8 signal
254 Cholestatic Liver Injury 13 4.7 4.7 signal
255 Diffuse Large B-cell Lymphoma Recurrent 13 4.7 4.7 signal
256 Skin Fissures 114 4.7 4.7 signal
257 Volvulus 14 4.7 4.7 signal
258 Pleural Effusion 365 4.7 4.7 signal
259 Corneal Disorder 13 4.7 4.7 signal
260 Tumour Haemorrhage 17 4.6 4.6 signal
261 Diarrhoea 3,802 4.6 5.2 signal
262 Hepatic Function Abnormal 214 4.5 4.5 signal
263 Sars-cov-2 Test Positive 77 4.5 4.5 signal
264 Hepatic Mass 11 4.5 4.5 signal
265 Bicytopenia 11 4.4 4.4 signal
266 Bundle Branch Block Left 24 4.4 4.4 signal
267 Cutaneous Lupus Erythematosus 11 4.4 4.4 signal
268 Cellulitis 280 4.3 4.4 signal
269 Schizophrenia 67 4.3 4.3 signal
270 Epistaxis 409 4.3 4.3 signal
271 Mean Cell Volume Increased 14 4.2 4.2 signal
272 Transaminases Increased 121 4.2 4.3 signal
273 Lung Opacity 14 4.2 4.2 signal
274 Gingival Pain 43 4.2 4.2 signal
275 Neoplasm 62 4.2 4.2 signal
276 Neutropenic Colitis 11 4.2 4.2 signal
277 Agranulocytosis 98 4.1 4.1 signal
278 Biliary Colic 15 4.1 4.1 signal
279 Pustule 12 4.1 4.1 signal
280 Subcutaneous Abscess 25 4.1 4.1 signal
281 Hepatotoxicity 114 4.0 4.0 signal
282 Pathological Fracture 26 4.0 4.0 signal
283 Duodenal Ulcer 36 4.0 4.0 signal
284 Hypoalbuminaemia 39 4.0 4.0 signal
285 Rash Pustular 37 3.9 3.9 signal
286 Cardiac Failure 406 3.9 4.0 signal
287 Second Primary Malignancy 42 3.9 3.9 signal
288 Hyperchlorhydria 30 3.9 3.9 signal
289 Electrolyte Imbalance 58 3.9 3.9 signal
290 Bone Pain 294 3.9 3.9 signal
291 Orthopnoea 16 3.9 3.9 signal
292 Thrombocytopenia 558 3.9 4.0 signal
293 Blood Chloride Decreased 13 3.9 3.9 signal
294 Anal Haemorrhage 14 3.9 3.9 signal
295 Acute Pulmonary Oedema 28 3.9 3.9 signal
296 Performance Status Decreased 23 3.8 3.8 signal
297 Hepatic Neoplasm 16 3.8 3.8 signal
298 Vaginal Infection 23 3.8 3.8 signal
299 Osteonecrosis Of Jaw 121 3.8 3.8 signal
300 Central Nervous System Lesion 67 3.8 3.8 signal
301 Candida Infection 80 3.7 3.7 signal
302 Hypocalcaemia 90 3.7 3.7 signal
303 Hyperbilirubinaemia 49 3.7 3.7 signal
304 Thoracic Vertebral Fracture 14 3.7 3.7 signal
305 Haemangioma 11 3.7 3.7 signal
306 Eosinophil Count Decreased 11 3.7 3.7 signal
307 Wound Dehiscence 16 3.7 3.7 signal
308 Hepatic Cyst 16 3.7 3.7 signal
309 Rhinitis 38 3.7 3.7 signal
310 White Blood Cell Count Abnormal 30 3.7 3.7 signal
311 Mouth Ulceration 99 3.7 3.7 signal
312 Skin Erosion 15 3.7 3.7 signal
313 Chills 550 3.6 3.7 signal
314 Poor Peripheral Circulation 20 3.6 3.6 signal
315 Impaired Quality Of Life 67 3.6 3.6 signal
316 Anaemia 885 3.6 3.7 signal
317 Pneumothorax 73 3.6 3.6 signal
318 Colitis 171 3.5 3.5 signal
319 Gingival Swelling 20 3.5 3.5 signal
320 Lower Respiratory Tract Infection 205 3.5 3.5 signal
321 Heart Valve Incompetence 13 3.5 3.5 signal
322 Protein Total Decreased 17 3.5 3.5 signal
323 Haemorrhoids 88 3.5 3.5 signal
324 Escherichia Urinary Tract Infection 19 3.5 3.5 signal
325 Necrosis 25 3.5 3.5 signal
326 Colitis Ischaemic 30 3.5 3.5 signal
327 Platelet Count Decreased 475 3.5 3.5 signal
328 White Blood Cell Count Decreased 482 3.5 3.5 signal
329 Aphthous Ulcer 34 3.4 3.5 signal
330 Sarcoidosis 21 3.4 3.4 signal
331 Food Poisoning 23 3.4 3.4 signal
332 Oesophageal Pain 17 3.4 3.4 signal
333 Blepharitis 17 3.4 3.4 signal
334 Febrile Bone Marrow Aplasia 18 3.3 3.3 signal
335 Skin Hypertrophy 12 3.3 3.3 signal
336 Blood Bilirubin Increased 116 3.3 3.3 signal
337 Blood Lactate Dehydrogenase Increased 68 3.3 3.3 signal
338 Pericardial Effusion 98 3.3 3.3 signal
339 Paranasal Sinus Discomfort 16 3.3 3.3 signal
340 Tumour Lysis Syndrome 37 3.3 3.3 signal
341 Cardiac Tamponade 20 3.3 3.3 signal
342 Hepatitis Toxic 11 3.3 3.3 signal
343 Lung Infiltration 37 3.2 3.2 signal
344 Faeces Soft 30 3.2 3.2 signal
345 Hypertensive Crisis 46 3.2 3.2 signal
346 Scleroderma 15 3.2 3.2 signal
347 Dermatitis 85 3.2 3.2 signal
348 Hyperthermia 31 3.2 3.2 signal
349 Hallucination, Auditory 65 3.2 3.2 signal
350 Cardiac Failure Acute 27 3.2 3.2 signal
351 Aspartate Aminotransferase Increased 213 3.1 3.1 signal
352 Pulmonary Toxicity 28 3.1 3.1 signal
353 Lung Neoplasm 17 3.1 3.1 signal
354 Embolism 33 3.1 3.1 signal
355 Oesophagitis 43 3.1 3.1 signal
356 Cerebral Disorder 29 3.1 3.1 signal
357 Anaphylactoid Reaction 16 3.0 3.0 signal
358 Lymphadenopathy 138 3.0 3.0 signal
359 Onychomycosis 17 3.0 3.0 signal
360 Neurological Symptom 22 3.0 3.0 signal
361 Granulocytopenia 22 3.0 3.0 signal
362 Clostridial Infection 13 3.0 3.0 signal
363 Oxygen Saturation Decreased 211 2.9 3.0 signal
364 Red Blood Cell Count Decreased 108 2.9 2.9 signal
365 Vein Disorder 19 2.9 2.9 signal
366 Alanine Aminotransferase Increased 231 2.9 2.9 signal
367 Anal Fissure 20 2.9 2.9 signal
368 Anaphylactic Shock 96 2.9 2.9 signal
369 Neurodermatitis 13 2.9 2.9 signal
370 Haematocrit Decreased 74 2.9 2.9 signal
371 Pneumocystis Jirovecii Pneumonia 37 2.9 2.9 signal
372 Conjunctivitis 68 2.9 2.9 signal
373 Dysgeusia 276 2.9 2.9 signal
374 Exercise Tolerance Decreased 21 2.9 2.9 signal
375 Ischaemia 17 2.9 2.9 signal
376 Appendicitis 34 2.8 2.8 signal
377 Gastroenteritis 53 2.8 2.8 signal
378 Gastritis 95 2.8 2.8 signal
379 Clostridium Difficile Infection 78 2.8 2.8 signal
380 Leukocytosis 65 2.8 2.8 signal
381 Urosepsis 33 2.8 2.8 signal
382 Malignant Neoplasm Progression 364 2.8 2.8 signal
383 Gamma-glutamyltransferase Increased 78 2.7 2.7 signal
384 Left Ventricular Failure 12 2.7 2.7 signal
385 Nasal Discomfort 28 2.7 2.7 signal
386 Ascites 103 2.7 2.7 signal
387 Spinal Pain 41 2.7 2.7 signal
388 Azotaemia 14 2.7 2.7 signal
389 Granuloma 12 2.7 2.7 signal
390 Oral Candidiasis 45 2.7 2.7 signal
391 Blood Alkaline Phosphatase Increased 86 2.7 2.7 signal
392 Haemorrhoidal Haemorrhage 17 2.7 2.7 signal
393 Skin Abrasion 16 2.7 2.7 signal
394 Flank Pain 32 2.7 2.7 signal
395 Pancytopenia 190 2.7 2.7 signal
396 Uterine Leiomyoma 25 2.6 2.7 signal
397 Respiratory Tract Infection 88 2.6 2.6 signal
398 Jaundice Cholestatic 12 2.6 2.6 signal
399 No Adverse Event 599 2.6 2.7 signal
400 Musculoskeletal Chest Pain 51 2.6 2.6 signal
401 Hepatic Pain 14 2.5 2.5 signal
402 Blood Pressure Systolic Increased 64 2.5 2.5 signal
403 Iron Deficiency Anaemia 30 2.5 2.5 signal
404 Compression Fracture 17 2.5 2.5 signal
405 Catatonia 17 2.5 2.5 signal
406 Laryngeal Oedema 20 2.5 2.5 signal
407 Sinus Tachycardia 46 2.5 2.5 signal
408 Bone Marrow Failure 66 2.5 2.5 signal
409 Maternal Exposure Timing Unspecified 12 2.5 2.5 signal
410 Erythema Multiforme 30 2.5 2.5 signal
411 Hydronephrosis 24 2.5 2.5 signal
412 Blood Test Abnormal 45 2.5 2.5 signal
413 Clostridium Difficile Colitis 34 2.5 2.5 signal
414 Blood Calcium Decreased 36 2.5 2.5 signal
415 Functional Gastrointestinal Disorder 11 2.5 2.5 signal
416 Large Intestine Perforation 22 2.5 2.5 signal
417 Oral Pain 71 2.5 2.5 signal
418 Extrapyramidal Disorder 79 2.4 2.5 signal
419 Enteritis 20 2.4 2.4 signal
420 C-reactive Protein Increased 114 2.4 2.4 signal
421 Depressive Symptom 11 2.4 2.4 signal
422 Renal Pain 33 2.4 2.4 signal
423 Hyperventilation 18 2.4 2.4 signal
424 Pyrexia 1,065 2.4 2.4 signal
425 Dehydration 410 2.4 2.4 signal
426 Bronchospasm 44 2.4 2.4 signal
427 Blood Potassium Decreased 92 2.4 2.4 signal
428 Acute Respiratory Distress Syndrome 54 2.4 2.4 signal
429 Retinal Detachment 28 2.4 2.4 signal
430 Decreased Appetite 702 2.4 2.4 signal
431 Hypernatraemia 15 2.3 2.3 signal
432 Blood Pressure Diastolic Increased 14 2.3 2.3 signal
433 Liver Injury 73 2.3 2.3 signal
434 Skin Reaction 42 2.3 2.3 signal
435 Liver Function Test Increased 63 2.3 2.3 signal
436 Product Temperature Excursion Issue 14 2.3 2.3 signal
437 Hydrocephalus 16 2.3 2.3 signal
438 Cachexia 15 2.3 2.3 signal
439 Neuralgia 71 2.3 2.3 signal
440 Hypovolaemia 17 2.3 2.3 signal
441 Intentional Product Use Issue 255 2.3 2.3 signal
442 General Physical Health Deterioration 333 2.3 2.3 signal
443 Taste Disorder 58 2.2 2.3 signal
444 Dyspnoea Exertional 108 2.2 2.2 signal
445 Tachycardia 255 2.2 2.2 signal
446 Defaecation Urgency 20 2.2 2.2 signal
447 Mouth Haemorrhage 21 2.2 2.2 signal
448 Dry Throat 29 2.2 2.2 signal
449 Rectal Haemorrhage 123 2.2 2.2 signal
450 Incorrect Drug Administration Rate 12 2.2 2.2 signal
451 Breath Sounds Abnormal 14 2.2 2.2 signal
452 Sepsis 316 2.2 2.2 signal
453 Drug-induced Liver Injury 87 2.2 2.2 signal
454 Hiccups 23 2.2 2.2 signal
455 Breast Cancer 265 2.2 2.2 signal
456 Localised Oedema 13 2.2 2.2 signal
457 Chest Discomfort 286 2.2 2.2 signal
458 Blood Iron Decreased 33 2.2 2.2 signal
459 Thrombotic Microangiopathy 27 2.2 2.2 signal
460 Hepatic Failure 84 2.2 2.2 signal
461 Vomiting 1,298 2.2 2.2 signal
462 Laryngitis 30 2.1 2.1 signal
463 Osteopenia 42 2.1 2.1 signal
464 Dyspepsia 270 2.1 2.1 signal
465 Temperature Intolerance 28 2.1 2.1 signal
466 Urinary Tract Infection 466 2.1 2.1 signal
467 Body Temperature Increased 56 2.1 2.1 signal
468 Off Label Use 2,368 2.1 2.2 signal
469 Pulse Absent 13 2.1 2.1 signal
470 Skin Mass 18 2.1 2.1 signal
471 Tonsillitis 14 2.1 2.1 signal
472 Nodule 35 2.1 2.1 signal
473 Hypercalcaemia 33 2.1 2.1 signal
474 Extravasation 11 2.1 2.1 signal
475 Myocarditis 30 2.1 2.1 signal
476 Hepatomegaly 26 2.0 2.0 signal
477 Dysuria 97 2.0 2.0 signal
478 Blood Disorder 21 2.0 2.0 signal
479 Rhinorrhoea 168 2.0 2.0 signal
480 Hair Growth Abnormal 18 2.0 2.0 signal
481 Paraesthesia 408 2.0 2.0 signal
482 Tachypnoea 35 2.0 2.0 signal
483 Aortic Valve Incompetence 11 2.0 2.0 signal
484 Coronary Artery Stenosis 13 2.0 2.0 signal
485 Pain In Jaw 73 2.0 2.0 signal
486 Constipation 556 2.0 2.0 no signal
487 Anaphylactic Reaction 141 2.0 2.0 no signal
488 Ill-defined Disorder 156 2.0 2.0 no signal
489 Colitis Microscopic 12 2.0 2.0 no signal
490 Epilepsy 78 2.0 2.0 no signal
491 Nasal Dryness 16 2.0 2.0 no signal
492 Endocarditis 13 2.0 2.0 no signal
493 Tricuspid Valve Incompetence 20 2.0 2.0 no signal
494 Diverticulum Intestinal 11 2.0 2.0 no signal
495 Partial Seizures 13 2.0 2.0 no signal
496 Bone Cancer 11 2.0 2.0 no signal
497 Circulatory Collapse 43 2.0 2.0 no signal
498 Macular Oedema 14 1.9 1.9 no signal
499 Visual Field Defect 18 1.9 1.9 no signal
500 Rash Vesicular 12 1.9 1.9 no signal
501 Ovarian Cyst 25 1.9 1.9 no signal
502 Wound Infection 27 1.9 1.9 no signal
503 Nausea 1,958 1.9 2.0 no signal
504 Ileus Paralytic 11 1.9 1.9 no signal
505 Fatigue 1,921 1.9 2.0 no signal
506 Immune Thrombocytopenia 11 1.9 1.9 no signal
507 Hepatic Cytolysis 30 1.9 1.9 no signal
508 Brain Neoplasm Malignant 11 1.9 1.9 no signal
509 Pulmonary Embolism 233 1.9 1.9 no signal
510 Ileus 30 1.9 1.9 no signal
511 Psychotic Disorder 72 1.9 1.9 no signal
512 Generalised Oedema 30 1.9 1.9 no signal
513 Disease Recurrence 116 1.9 1.9 no signal
514 Sensory Disturbance 39 1.9 1.9 no signal
515 Ventricular Extrasystoles 25 1.9 1.9 no signal
516 Blood Albumin Decreased 19 1.9 1.9 no signal
517 Angina Pectoris 69 1.9 1.9 no signal
518 Toxic Epidermal Necrolysis 36 1.9 1.9 no signal
519 Incorrect Route Of Product Administration 40 1.8 1.8 no signal
520 Hypoaesthesia 354 1.8 1.8 no signal
521 Hot Flush 178 1.8 1.8 no signal
522 Mass 33 1.8 1.8 no signal
523 Pulmonary Fibrosis 45 1.8 1.8 no signal
524 Gastritis Erosive 11 1.8 1.8 no signal
525 Seizure 269 1.8 1.8 no signal
526 Cytopenia 28 1.8 1.8 no signal
527 Post Procedural Infection 19 1.8 1.8 no signal
528 Concussion 18 1.8 1.8 no signal
529 Pyelonephritis 20 1.8 1.8 no signal
530 Myalgia 393 1.8 1.8 no signal
531 Malabsorption 12 1.8 1.8 no signal
532 Pulmonary Hypertension 48 1.8 1.8 no signal
533 Swelling Of Eyelid 14 1.8 1.8 no signal
534 Aphonia 32 1.8 1.8 no signal
535 Neutrophilia 13 1.8 1.8 no signal
536 Hypokinesia 33 1.8 1.8 no signal
537 Seasonal Allergy 32 1.8 1.8 no signal
538 Tooth Abscess 23 1.7 1.7 no signal
539 Asthenia 843 1.7 1.8 no signal
540 Ageusia 56 1.7 1.7 no signal
541 Bone Disorder 41 1.7 1.7 no signal
542 Dry Eye 108 1.7 1.7 no signal
543 Hepatitis 57 1.7 1.7 no signal
544 Eczema 112 1.7 1.7 no signal
545 Intestinal Perforation 25 1.7 1.7 no signal
546 Decubitus Ulcer 18 1.7 1.7 no signal
547 Abdominal Pain 510 1.7 1.7 no signal
548 Blood Sodium Decreased 41 1.7 1.7 no signal
549 Rash 940 1.7 1.7 no signal
550 Malnutrition 24 1.7 1.7 no signal
551 Drug Resistance 55 1.7 1.7 no signal
552 Folliculitis 22 1.7 1.7 no signal
553 Face Oedema 36 1.6 1.7 no signal
554 Parosmia 16 1.6 1.6 no signal
555 Dyspnoea 1,197 1.6 1.7 no signal
556 Back Pain 491 1.6 1.7 no signal
557 Oedema Peripheral 257 1.6 1.6 no signal
558 Skin Hyperpigmentation 18 1.6 1.6 no signal
559 Cystitis 67 1.6 1.6 no signal
560 Dermatitis Bullous 15 1.6 1.6 no signal
561 Foreign Body Sensation In Eyes 13 1.6 1.6 no signal
562 Herpes Virus Infection 12 1.6 1.6 no signal
563 Skin Disorder 69 1.6 1.6 no signal
564 Dysmenorrhoea 27 1.6 1.6 no signal
565 Spinal Fracture 41 1.6 1.6 no signal
566 Anal Abscess 11 1.6 1.6 no signal
567 Respiration Abnormal 14 1.6 1.6 no signal
568 Acute Kidney Injury 309 1.6 1.6 no signal
569 Diarrhoea Haemorrhagic 19 1.6 1.6 no signal
570 Feeling Cold 56 1.6 1.6 no signal
571 Abscess 32 1.6 1.6 no signal
572 Myositis 18 1.6 1.6 no signal
573 Herpes Simplex 13 1.6 1.6 no signal
574 Lethargy 115 1.6 1.6 no signal
575 Restlessness 73 1.5 1.5 no signal
576 Lower Limb Fracture 38 1.5 1.5 no signal
577 Supraventricular Tachycardia 19 1.5 1.5 no signal
578 Drug Eruption 35 1.5 1.5 no signal
579 Heart Rate Decreased 70 1.5 1.5 no signal
580 Weight Decreased 553 1.5 1.5 no signal
581 Cyanosis 31 1.5 1.5 no signal
582 Eye Infection 22 1.5 1.5 no signal
583 Oral Herpes 38 1.5 1.5 no signal
584 Bacteraemia 23 1.5 1.5 no signal
585 Vitamin D Deficiency 19 1.5 1.5 no signal
586 Concomitant Disease Aggravated 12 1.5 1.5 no signal
587 Acute Generalised Exanthematous Pustulosis 15 1.5 1.5 no signal
588 Gastrointestinal Pain 21 1.5 1.5 no signal
589 Disseminated Intravascular Coagulation 27 1.5 1.5 no signal
590 Respiratory Rate Increased 17 1.5 1.5 no signal
591 Hypophosphataemia 14 1.5 1.5 no signal
592 Spinal Compression Fracture 16 1.5 1.5 no signal
593 Oedema 103 1.5 1.5 no signal
594 Pseudomonas Infection 16 1.5 1.5 no signal
595 Cholestasis 36 1.5 1.5 no signal
596 Pneumonia 609 1.5 1.5 no signal
597 Sudden Death 20 1.5 1.5 no signal
598 Flushing 191 1.5 1.5 no signal
599 Vertigo 114 1.5 1.5 no signal
600 Presyncope 45 1.4 1.4 no signal
601 Haemoglobin Decreased 191 1.4 1.4 no signal
602 Extrasystoles 13 1.4 1.4 no signal
603 Hypotension 371 1.4 1.4 no signal
604 Poor Venous Access 19 1.4 1.4 no signal
605 Palpitations 214 1.4 1.4 no signal
606 Hepatic Encephalopathy 17 1.4 1.4 no signal
607 Hypophagia 46 1.4 1.4 no signal
608 Cough 507 1.4 1.4 no signal
609 Dry Skin 238 1.4 1.4 no signal
610 Vasculitis 21 1.4 1.4 no signal
611 Hypoaesthesia Oral 27 1.4 1.4 no signal
612 Pulmonary Arterial Hypertension 26 1.4 1.4 no signal
613 Postoperative Wound Infection 12 1.4 1.4 no signal
614 Respiratory Distress 49 1.4 1.4 no signal
615 Hepatic Steatosis 33 1.4 1.4 no signal
616 Pulmonary Oedema 79 1.4 1.4 no signal
617 Renal Cyst 14 1.4 1.4 no signal
618 Atelectasis 17 1.4 1.4 no signal
619 Hyperlipidaemia 21 1.4 1.4 no signal
620 Stevens-johnson Syndrome 39 1.4 1.4 no signal
621 Tooth Infection 23 1.4 1.4 no signal
622 Myocardial Ischaemia 20 1.4 1.4 no signal
623 Multiple Organ Dysfunction Syndrome 48 1.3 1.3 no signal
624 Hypogammaglobulinaemia 11 1.3 1.3 no signal
625 Body Temperature Decreased 17 1.3 1.3 no signal
626 Lymphopenia 24 1.3 1.3 no signal
627 Vaginal Discharge 17 1.3 1.3 no signal
628 Peritonitis 35 1.3 1.3 no signal
629 Thermal Burn 12 1.3 1.3 no signal
630 Skin Lesion 46 1.3 1.3 no signal
631 Cholecystitis 20 1.3 1.3 no signal
632 Hypoxia 59 1.3 1.3 no signal
633 Toxic Skin Eruption 17 1.3 1.3 no signal
634 Haemolysis 13 1.3 1.3 no signal
635 Cytokine Release Syndrome 32 1.3 1.3 no signal
636 Hyperglycaemia 61 1.3 1.3 no signal
637 Melaena 37 1.3 1.3 no signal
638 Blood Pressure Decreased 111 1.3 1.3 no signal
639 Hyponatraemia 94 1.3 1.3 no signal
640 Acute Myeloid Leukaemia 26 1.3 1.3 no signal
641 Myelodysplastic Syndrome 24 1.3 1.3 no signal
642 Device Occlusion 23 1.3 1.3 no signal
643 Haematoma 43 1.3 1.3 no signal
644 Hypersensitivity 306 1.3 1.3 no signal
645 Pruritus 616 1.3 1.3 no signal
646 Rash Maculo-papular 36 1.3 1.3 no signal
647 Eyelid Oedema 19 1.3 1.3 no signal
648 No Therapeutic Response 20 1.3 1.3 no signal
649 Lymphoma 25 1.3 1.3 no signal
650 Cardiogenic Shock 23 1.3 1.3 no signal
651 Glossodynia 36 1.2 1.2 no signal
652 Sneezing 36 1.2 1.2 no signal
653 Influenza Like Illness 132 1.2 1.2 no signal
654 Escherichia Infection 13 1.2 1.2 no signal
655 Oropharyngeal Pain 147 1.2 1.2 no signal
656 Hypertension 336 1.2 1.2 no signal
657 Altered State Of Consciousness 34 1.2 1.2 no signal
658 Nasopharyngitis 291 1.2 1.2 no signal
659 Dysphagia 149 1.2 1.2 no signal
660 Septic Shock 68 1.2 1.2 no signal
661 Oropharyngeal Discomfort 14 1.2 1.2 no signal
662 Gastrointestinal Disorder 138 1.2 1.2 no signal
663 Infection 225 1.2 1.2 no signal
664 Upper Respiratory Tract Infection 72 1.2 1.2 no signal
665 Cardiac Disorder 146 1.2 1.2 no signal
666 Deep Vein Thrombosis 101 1.2 1.2 no signal
667 Gastroenteritis Viral 28 1.2 1.2 no signal
668 Haematuria 53 1.2 1.2 no signal
669 Erythema 317 1.2 1.2 no signal
670 Tendonitis 24 1.2 1.2 no signal
671 Petechiae 16 1.2 1.2 no signal
672 Ventricular Fibrillation 17 1.2 1.2 no signal
673 Nerve Injury 17 1.2 1.2 no signal
674 Joint Stiffness 40 1.2 1.2 no signal
675 Dry Mouth 123 1.2 1.2 no signal
676 Skin Ulcer 39 1.2 1.2 no signal
677 Ulcer 24 1.2 1.2 no signal
678 Incorrect Product Storage 20 1.2 1.2 no signal
679 Blood Creatinine Increased 98 1.2 1.2 no signal
680 Osteomyelitis 27 1.2 1.2 no signal
681 Chest Pain 276 1.2 1.2 no signal
682 Colon Cancer 22 1.1 1.1 no signal
683 Liver Disorder 65 1.1 1.1 no signal
684 Visual Acuity Reduced 49 1.1 1.1 no signal
685 Feeding Disorder 29 1.1 1.1 no signal
686 Blood Pressure Fluctuation 35 1.1 1.1 no signal
687 Peripheral Coldness 20 1.1 1.1 no signal
688 Dermatitis Allergic 18 1.1 1.1 no signal
689 Night Sweats 46 1.1 1.1 no signal
690 Immunodeficiency 21 1.1 1.1 no signal
691 Gastrooesophageal Reflux Disease 114 1.1 1.1 no signal
692 Product Storage Error 123 1.1 1.1 no signal
693 Covid-19 251 1.1 1.1 no signal
694 Syncope 139 1.1 1.1 no signal
695 Heavy Menstrual Bleeding 11 1.1 1.1 no signal
696 Arteriosclerosis 13 1.1 1.1 no signal
697 Tremor 229 1.1 1.1 no signal
698 Cardiovascular Disorder 35 1.1 1.1 no signal
699 Blood Calcium Increased 12 1.1 1.1 no signal
700 Localised Infection 33 1.1 1.1 no signal
701 Spinal Osteoarthritis 12 1.1 1.1 no signal
702 Rash Pruritic 73 1.0 1.1 no signal
703 Muscle Atrophy 17 1.0 1.0 no signal
704 Asphyxia 11 1.0 1.0 no signal
705 Scar 23 1.0 1.0 no signal
706 Pain Of Skin 36 1.0 1.0 no signal
707 Wound 37 1.0 1.0 no signal
708 Drug Intolerance 128 1.0 1.0 no signal
709 Lung Disorder 65 1.0 1.0 no signal
710 Coagulopathy 22 1.0 1.0 no signal
711 Scab 15 1.0 1.0 no signal
712 Micturition Urgency 15 1.0 1.0 no signal
713 Nocturia 16 1.0 1.0 no signal
714 Diplopia 34 1.0 1.0 no signal
715 Cerebral Infarction 32 1.0 1.0 no signal
716 Acute Respiratory Failure 25 1.0 1.0 no signal
717 Haematemesis 33 1.0 1.0 no signal
718 Gastric Haemorrhage 15 1.0 1.0 no signal
719 Bacterial Infection 24 1.0 1.0 no signal
720 Emphysema 13 1.0 1.0 no signal
721 Death 1,104 1.0 1.0 no signal
722 Musculoskeletal Discomfort 22 1.0 1.0 no signal
723 Nervous System Disorder 40 1.0 1.0 no signal
724 Muscular Weakness 145 1.0 1.0 no signal
725 Muscle Spasms 234 1.0 1.0 no signal
726 Heart Rate Increased 126 1.0 1.0 no signal
727 Eye Discharge 13 1.0 1.0 no signal
728 Myopathy 11 1.0 1.0 no signal
729 Poor Quality Sleep 27 1.0 1.0 no signal
730 Jaundice 34 1.0 1.0 no signal
731 Underdose 92 1.0 1.0 no signal
732 Ataxia 15 1.0 1.0 no signal
733 Cardiac Failure Congestive 102 1.0 1.0 no signal
734 Impaired Gastric Emptying 16 1.0 1.0 no signal
735 Tooth Disorder 28 1.0 1.0 no signal
736 Skin Exfoliation 104 1.0 1.0 no signal
737 Cholelithiasis 41 1.0 1.0 no signal
738 Groin Pain 11 1.0 1.0 no signal
739 Pallor 34 1.0 1.0 no signal
740 Gingival Bleeding 17 1.0 1.0 no signal
741 Fistula 14 1.0 1.0 no signal
742 Headache 777 1.0 1.0 no signal
743 Atrial Fibrillation 121 1.0 1.0 no signal
744 Arrhythmia 59 1.0 1.0 no signal
745 Gastrointestinal Infection 11 1.0 1.0 no signal
746 Shock 28 1.0 1.0 no signal
747 Haemolytic Anaemia 11 0.9 0.9 no signal
748 Abdominal Pain Lower 31 0.9 0.9 no signal
749 Respiratory Failure 89 0.9 0.9 no signal
750 Rash Erythematous 57 0.9 0.9 no signal
751 Pelvic Pain 22 0.9 0.9 no signal
752 Gastric Ulcer 23 0.9 0.9 no signal
753 Blindness 49 0.9 0.9 no signal
754 Eye Haemorrhage 16 0.9 0.9 no signal
755 Blister 67 0.9 0.9 no signal
756 Brain Injury 12 0.9 0.9 no signal
757 Herpes Zoster 68 0.9 0.9 no signal
758 Thrombosis 95 0.9 0.9 no signal
759 Acute Hepatic Failure 16 0.9 0.9 no signal
760 Hemiparesis 20 0.9 0.9 no signal
761 Abdominal Pain Upper 241 0.9 0.9 no signal
762 Muscle Twitching 27 0.9 0.9 no signal
763 Unresponsive To Stimuli 30 0.9 0.9 no signal
764 Dementia 32 0.9 0.9 no signal
765 Small Intestinal Obstruction 14 0.9 0.9 no signal
766 Productive Cough 54 0.9 0.9 no signal
767 Arthralgia 468 0.9 0.9 no signal
768 Malaise 496 0.9 0.9 no signal
769 Peripheral Swelling 173 0.9 0.9 no signal
770 Upper Gastrointestinal Haemorrhage 19 0.9 0.9 no signal
771 Feeling Hot 69 0.9 0.9 no signal
772 Eating Disorder 24 0.9 0.9 no signal
773 Hepatic Enzyme Increased 76 0.9 0.9 no signal
774 Swelling 104 0.9 0.9 no signal
775 Post Procedural Haemorrhage 13 0.9 0.9 no signal
776 Paraesthesia Oral 16 0.9 0.9 no signal
777 Cataract 66 0.9 0.9 no signal
778 Unintentional Medical Device Removal 13 0.9 0.9 no signal
779 Hyperthyroidism 16 0.9 0.9 no signal
780 Respiratory Disorder 33 0.9 0.9 no signal
781 Photosensitivity Reaction 18 0.8 0.8 no signal
782 Covid-19 Pneumonia 13 0.8 0.8 no signal
783 Orthostatic Hypotension 19 0.8 0.8 no signal
784 Diverticulitis 30 0.8 0.8 no signal
785 Lung Infection 17 0.8 0.8 no signal
786 Throat Tightness 29 0.8 0.8 no signal
787 Panic Attack 39 0.8 0.8 no signal
788 Pain In Extremity 315 0.8 0.8 no signal
789 White Blood Cell Count Increased 41 0.8 0.8 no signal
790 Dysarthria 40 0.8 0.8 no signal
791 Blood Creatine Phosphokinase Increased 31 0.8 0.8 no signal
792 Pain 637 0.8 0.8 no signal
793 Renal Impairment 86 0.8 0.8 no signal
794 Insomnia 274 0.8 0.8 no signal
795 Skin Discolouration 47 0.8 0.8 no signal
796 Kidney Infection 20 0.8 0.8 no signal
797 Amenorrhoea 17 0.8 0.8 no signal
798 Photophobia 19 0.8 0.8 no signal
799 Bronchitis 75 0.8 0.8 no signal
800 Loss Of Consciousness 129 0.8 0.8 no signal
801 Fracture 19 0.8 0.8 no signal
802 Burning Sensation 70 0.8 0.8 no signal
803 Emotional Distress 121 0.8 0.8 no signal
804 Hepatocellular Injury 14 0.8 0.8 no signal
805 Dizziness 490 0.8 0.8 no signal
806 Skin Haemorrhage 14 0.8 0.8 no signal
807 Depressed Mood 51 0.8 0.8 no signal
808 Throat Irritation 43 0.7 0.7 no signal
809 Anxiety 274 0.7 0.7 no signal
810 Blood Pressure Increased 147 0.7 0.7 no signal
811 Dysphonia 56 0.7 0.7 no signal
812 Musculoskeletal Pain 50 0.7 0.7 no signal
813 Hyperhidrosis 122 0.7 0.7 no signal
814 Incontinence 10 0.7 0.7 no signal
815 Pollakiuria 39 0.7 0.7 no signal
816 Staphylococcal Infection 31 0.7 0.7 no signal
817 Rib Fracture 19 0.7 0.7 no signal
818 Aphasia 28 0.7 0.7 no signal
819 Cognitive Disorder 43 0.7 0.7 no signal
820 Therapy Non-responder 41 0.7 0.7 no signal
821 Adrenal Insufficiency 11 0.7 0.7 no signal
822 Deafness 24 0.7 0.7 no signal
823 Vision Blurred 125 0.7 0.7 no signal
824 Abdominal Distension 95 0.7 0.7 no signal
825 Hepatic Cirrhosis 17 0.7 0.7 no signal
826 Cardiac Arrest 75 0.7 0.7 no signal
827 Treatment Failure 73 0.7 0.7 no signal
828 Eyelid Ptosis 9 0.7 0.7 no signal
829 Pharyngitis 11 0.7 0.7 no signal
830 Stress 63 0.7 0.7 no signal
831 Discomfort 53 0.7 0.7 no signal
832 Neoplasm Malignant 58 0.7 0.7 no signal
833 Device Adhesion Issue 13 0.7 0.7 no signal
834 Liver Function Test Abnormal 25 0.7 0.7 no signal
835 Metabolic Acidosis 27 0.7 0.7 no signal
836 Cold Sweat 15 0.7 0.7 no signal
837 Eye Inflammation 8 0.7 0.7 no signal
838 Tinnitus 39 0.7 0.7 no signal
839 Surgery 49 0.7 0.7 no signal
840 Acute Myocardial Infarction 25 0.7 0.7 no signal
841 Dialysis 12 0.7 0.7 no signal
842 Full Blood Count Decreased 17 0.7 0.7 no signal
843 Spinal Disorder 8 0.7 0.7 no signal
844 Fungal Infection 28 0.7 0.7 no signal
845 Pregnancy 17 0.7 0.7 no signal
846 Rash Macular 29 0.6 0.6 no signal
847 Toothache 15 0.6 0.6 no signal
848 Weight Increased 184 0.6 0.6 no signal
849 Sciatica 13 0.6 0.6 no signal
850 Overdose 177 0.6 0.6 no signal
851 Visual Impairment 100 0.6 0.6 no signal
852 Cardiomegaly 10 0.6 0.6 no signal
853 Tooth Extraction 10 0.6 0.6 no signal
854 Toxicity To Various Agents 134 0.6 0.6 no signal
855 Influenza 89 0.6 0.6 no signal
856 Irritable Bowel Syndrome 17 0.6 0.6 no signal
857 Ear Discomfort 8 0.6 0.6 no signal
858 Pericarditis 13 0.6 0.6 no signal
859 Urinary Incontinence 23 0.6 0.6 no signal
860 Scratch 8 0.6 0.6 no signal
861 Ear Pain 15 0.6 0.6 no signal
862 Platelet Count Increased 10 0.6 0.6 no signal
863 Pneumonia Aspiration 19 0.6 0.6 no signal
864 Intentional Product Misuse 66 0.6 0.6 no signal
865 Procedural Pain 21 0.6 0.6 no signal
866 Coronary Artery Disease 23 0.6 0.6 no signal
867 Balance Disorder 65 0.6 0.6 no signal
868 Renal Failure 100 0.6 0.6 no signal
869 Fluid Retention 38 0.6 0.6 no signal
870 Tubulointerstitial Nephritis 14 0.6 0.6 no signal
871 Meningioma 11 0.6 0.6 no signal
872 Gastric Disorder 26 0.6 0.6 no signal
873 Impaired Work Ability 16 0.6 0.6 no signal
874 Inflammation 38 0.6 0.6 no signal
875 Back Injury 8 0.6 0.6 no signal
876 Ocular Discomfort 8 0.6 0.6 no signal
877 Respiratory Depression 9 0.6 0.6 no signal
878 Sleep Disorder 51 0.6 0.6 no signal
879 Ventricular Tachycardia 12 0.6 0.6 no signal
880 Osteonecrosis 24 0.6 0.6 no signal
881 Vitreous Floaters 7 0.6 0.6 no signal
882 Memory Impairment 98 0.6 0.6 no signal
883 Rash Papular 16 0.6 0.6 no signal
884 Femur Fracture 22 0.5 0.5 no signal
885 Prescribed Underdose 14 0.5 0.5 no signal
886 Acne 53 0.5 0.5 no signal
887 Gait Inability 23 0.5 0.5 no signal
888 Therapeutic Product Effect Incomplete 49 0.5 0.5 no signal
889 Depression 158 0.5 0.5 no signal
890 Speech Disorder 36 0.5 0.5 no signal
891 Brain Fog 10 0.5 0.5 no signal
892 Disturbance In Attention 37 0.5 0.5 no signal
893 Immune System Disorder 9 0.5 0.5 no signal
894 Hypoglycaemia 33 0.5 0.5 no signal
895 Weight Fluctuation 7 0.5 0.5 no signal
896 Eye Pain 37 0.5 0.5 no signal
897 Maternal Exposure During Pregnancy 59 0.5 0.5 no signal
898 Full Blood Count Abnormal 7 0.5 0.5 no signal
899 Thyroid Cancer 8 0.5 0.5 no signal
900 Glomerular Filtration Rate Decreased 8 0.5 0.5 no signal
901 Mood Swings 21 0.5 0.5 no signal
902 Circumstance Or Information Capable Of Leading To Medication Error 22 0.5 0.5 no signal
903 Blood Urea Increased 11 0.5 0.5 no signal
904 Hypoacusis 28 0.5 0.5 no signal
905 Skin Cancer 14 0.5 0.5 no signal
906 Product Use Issue 121 0.5 0.5 no signal
907 Swelling Face 42 0.5 0.5 no signal
908 Contusion 62 0.5 0.5 no signal
909 Intervertebral Disc Degeneration 6 0.5 0.5 no signal
910 Wheezing 38 0.5 0.5 no signal
911 Proteinuria 12 0.5 0.5 no signal
912 Posterior Reversible Encephalopathy Syndrome 6 0.5 0.5 no signal
913 Hypothyroidism 20 0.5 0.5 no signal
914 Amnesia 41 0.5 0.5 no signal
915 Autoimmune Disorder 6 0.5 0.5 no signal
916 Abortion Spontaneous 25 0.5 0.5 no signal
917 Transient Ischaemic Attack 21 0.5 0.5 no signal
918 Coeliac Disease 6 0.5 0.5 no signal
919 Generalised Tonic-clonic Seizure 10 0.5 0.5 no signal
920 Bedridden 8 0.5 0.5 no signal
921 Eye Pruritus 20 0.5 0.5 no signal
922 Condition Aggravated 183 0.5 0.5 no signal
923 Sinus Disorder 12 0.5 0.5 no signal
924 Sinusitis 62 0.5 0.5 no signal
925 Upper Limb Fracture 12 0.5 0.5 no signal
926 Mental Disorder 26 0.5 0.5 no signal
927 Motor Dysfunction 6 0.5 0.5 no signal
928 Hypothermia 6 0.5 0.5 no signal
929 Therapeutic Response Decreased 35 0.4 0.4 no signal
930 Impaired Healing 19 0.4 0.4 no signal
931 Mental Status Changes 16 0.4 0.4 no signal
932 Musculoskeletal Disorder 11 0.4 0.4 no signal
933 Viral Infection 19 0.4 0.4 no signal
934 Coordination Abnormal 8 0.4 0.4 no signal
935 Migraine 54 0.4 0.4 no signal
936 Dystonia 11 0.4 0.4 no signal
937 Premature Delivery 9 0.4 0.4 no signal
938 Paralysis 8 0.4 0.4 no signal
939 Blood Pressure Abnormal 11 0.4 0.4 no signal
940 Blood Potassium Increased 9 0.4 0.4 no signal
941 Urticaria 91 0.4 0.4 no signal
942 Dysstasia 16 0.4 0.4 no signal
943 Tuberculosis 7 0.4 0.4 no signal
944 Tooth Fracture 6 0.4 0.4 no signal
945 Angioedema 24 0.4 0.4 no signal
946 Gait Disturbance 104 0.4 0.4 no signal
947 Psychomotor Hyperactivity 9 0.4 0.4 no signal
948 Personality Change 5 0.4 0.4 no signal
949 Leukaemia 5 0.4 0.4 no signal
950 Adverse Reaction 7 0.4 0.4 no signal
951 Device Failure 8 0.4 0.4 no signal
952 Tooth Loss 11 0.4 0.4 no signal
953 Confusional State 85 0.4 0.4 no signal
954 Delirium 18 0.4 0.4 no signal
955 Blood Count Abnormal 8 0.4 0.4 no signal
956 Uveitis 7 0.4 0.4 no signal
957 Pharyngeal Oedema 8 0.4 0.4 no signal
958 Splenomegaly 6 0.4 0.4 no signal
959 Urinary Retention 17 0.4 0.4 no signal
960 Haemorrhage 53 0.4 0.4 no signal
961 Medication Error 28 0.4 0.4 no signal
962 Cerebral Haemorrhage 18 0.4 0.4 no signal
963 Hip Fracture 16 0.4 0.4 no signal
964 Rash Generalised 13 0.4 0.4 no signal
965 Restless Legs Syndrome 9 0.4 0.4 no signal
966 Haematochezia 27 0.4 0.4 no signal
967 Subarachnoid Haemorrhage 5 0.4 0.4 no signal
968 Illness 49 0.4 0.4 no signal
969 Secretion Discharge 6 0.4 0.4 no signal
970 Product Preparation Error 10 0.4 0.4 no signal
971 Neck Pain 27 0.4 0.4 no signal
972 Intestinal Obstruction 18 0.4 0.4 no signal
973 Mood Altered 13 0.4 0.4 no signal
974 Transfusion 5 0.4 0.4 no signal
975 Renal Disorder 22 0.4 0.4 no signal
976 Retching 10 0.4 0.4 no signal
977 Fall 155 0.4 0.4 no signal
978 Unevaluable Event 35 0.4 0.4 no signal
979 Pulmonary Thrombosis 5 0.4 0.4 no signal
980 Eye Disorder 15 0.4 0.4 no signal
981 Rhabdomyolysis 19 0.4 0.4 no signal
982 Thyroid Disorder 7 0.4 0.4 no signal
983 Cardio-respiratory Arrest 19 0.3 0.3 no signal
984 Foot Deformity 5 0.3 0.3 no signal
985 Encephalopathy 11 0.3 0.3 no signal
986 Sopor 6 0.3 0.3 no signal
987 Drug Effective For Unapproved Indication 13 0.3 0.3 no signal
988 Type 2 Diabetes Mellitus 15 0.3 0.3 no signal
989 Drug Ineffective 581 0.3 0.3 no signal
990 Drug Interaction 70 0.3 0.3 no signal
991 Gastrointestinal Haemorrhage 37 0.3 0.3 no signal
992 Internal Haemorrhage 5 0.3 0.3 no signal
993 Nerve Compression 4 0.3 0.3 no signal
994 Movement Disorder 14 0.3 0.3 no signal
995 Blood Thyroid Stimulating Hormone Increased 4 0.3 0.3 no signal
996 Oral Discomfort 6 0.3 0.3 no signal
997 Ocular Hyperaemia 20 0.3 0.3 no signal
998 Thinking Abnormal 8 0.3 0.3 no signal
999 Vaginal Haemorrhage 18 0.3 0.3 no signal
1000 Product Prescribing Error 10 0.3 0.3 no signal
1001 Myoclonus 5 0.3 0.3 no signal
1002 Diabetes Mellitus 32 0.3 0.3 no signal
1003 Somnolence 84 0.3 0.3 no signal
1004 Pharyngeal Swelling 4 0.3 0.3 no signal
1005 Pancreatitis 22 0.3 0.3 no signal
1006 Menstruation Irregular 11 0.3 0.3 no signal
1007 Incorrect Dose Administered 93 0.3 0.3 no signal
1008 Hospice Care 4 0.3 0.3 no signal
1009 Menorrhagia 8 0.3 0.3 no signal
1010 Injection Site Extravasation 5 0.3 0.3 no signal
1011 Coma 19 0.3 0.3 no signal
1012 Drug Hypersensitivity 77 0.3 0.3 no signal
1013 Sluggishness 4 0.3 0.3 no signal
1014 Inappropriate Antidiuretic Hormone Secretion 4 0.3 0.3 no signal
1015 Osteoporosis 16 0.3 0.3 no signal
1016 Rotator Cuff Syndrome 5 0.3 0.3 no signal
1017 Chronic Obstructive Pulmonary Disease 20 0.3 0.3 no signal
1018 Abdominal Discomfort 64 0.3 0.3 no signal
1019 Cerebrovascular Accident 65 0.3 0.3 no signal
1020 Breast Cancer Female 10 0.3 0.3 no signal
1021 Pharyngitis Streptococcal 4 0.3 0.3 no signal
1022 Adverse Event 34 0.3 0.3 no signal
1023 Systemic Lupus Erythematosus 13 0.3 0.3 no signal
1024 Feeling Abnormal 87 0.3 0.3 no signal
1025 Lip Swelling 12 0.3 0.3 no signal
1026 Nephropathy Toxic 4 0.3 0.3 no signal
1027 Adverse Drug Reaction 32 0.3 0.3 no signal
1028 Limb Discomfort 11 0.3 0.3 no signal
1029 Blindness Unilateral 5 0.3 0.3 no signal
1030 Asthma 39 0.3 0.3 no signal
1031 Myocardial Infarction 61 0.3 0.3 no signal
1032 Musculoskeletal Stiffness 30 0.3 0.3 no signal
1033 Ischaemic Stroke 6 0.3 0.3 no signal
1034 Muscle Rigidity 4 0.3 0.3 no signal
1035 Electrocardiogram Qt Prolonged 12 0.3 0.3 no signal
1036 Product Use In Unapproved Indication 81 0.3 0.3 no signal
1037 Intercepted Product Preparation Error 4 0.3 0.3 no signal
1038 Nephrolithiasis 15 0.3 0.3 no signal
1039 Disorientation 13 0.3 0.3 no signal
1040 Gastrointestinal Carcinoma 3 0.3 0.3 no signal
1041 Nasal Congestion 19 0.3 0.3 no signal
1042 Joint Swelling 39 0.3 0.2 no signal
1043 Device Use Error 11 0.3 0.2 no signal
1044 Device Dislocation 14 0.3 0.2 no signal
1045 Foetal Exposure During Pregnancy 26 0.2 0.2 no signal
1046 Arthritis 25 0.2 0.2 no signal
1047 Poisoning 4 0.2 0.2 no signal
1048 Hyperkalaemia 11 0.2 0.2 no signal
1049 Inability To Afford Medication 3 0.2 0.2 no signal
1050 Renal Failure Acute 13 0.2 0.2 no signal
1051 Blood Cholesterol Increased 14 0.2 0.2 no signal
1052 Premature Baby 9 0.2 0.2 no signal
1053 Injury 21 0.2 0.2 no signal
1054 Therapeutic Product Effect Decreased 13 0.2 0.2 no signal
1055 Lung Neoplasm Malignant 12 0.2 0.2 no signal
1056 Emotional Disorder 9 0.2 0.2 no signal
1057 Metrorrhagia 5 0.2 0.2 no signal
1058 Eye Irritation 16 0.2 0.2 no signal
1059 Nervousness 15 0.2 0.2 no signal
1060 Local Swelling 5 0.2 0.2 no signal
1061 Drug Administered At Inappropriate Site 3 0.2 0.2 no signal
1062 Injection Site Haemorrhage 22 0.2 0.2 no signal
1063 Anosmia 4 0.2 0.2 no signal
1064 Chronic Kidney Disease 21 0.2 0.2 no signal
1065 Agitation 20 0.2 0.2 no signal
1066 Bradycardia 14 0.2 0.2 no signal
1067 Skin Irritation 12 0.2 0.2 no signal
1068 Sexual Dysfunction 3 0.2 0.2 no signal
1069 Skin Burning Sensation 18 0.2 0.2 no signal
1070 Hepatitis C 3 0.2 0.2 no signal
1071 Cytomegalovirus Infection 4 0.2 0.2 no signal
1072 Mobility Decreased 17 0.2 0.2 no signal
1073 Drug Ineffective For Unapproved Indication 13 0.2 0.2 no signal
1074 Blood Glucose Increased 44 0.2 0.2 no signal
1075 Therapy Interrupted 16 0.2 0.2 no signal
1076 Flatulence 13 0.2 0.2 no signal
1077 Device Breakage 9 0.2 0.2 no signal
1078 Diabetic Ketoacidosis 5 0.2 0.2 no signal
1079 Arthropathy 11 0.2 0.2 no signal
1080 Irritability 11 0.1 0.1 no signal
1081 Application Site Pain 4 0.1 0.1 no signal
1082 Multiple Sclerosis 8 0.1 0.1 no signal
1083 Hepatic Cancer 4 0.1 0.1 no signal
1084 Injection Site Reaction 11 0.1 0.1 no signal
1085 Product Complaint 4 0.1 0.1 no signal
1086 Hospitalisation 24 0.1 0.1 no signal
1087 Accidental Exposure To Product 14 0.1 0.1 no signal
1088 Needle Issue 4 0.1 0.1 no signal
1089 Injection Site Mass 5 0.1 0.1 no signal
1090 Device Malfunction 8 0.1 0.1 no signal
1091 Injection Site Pain 34 0.1 0.1 no signal
1092 Wrong Technique In Product Usage Process 22 0.1 0.1 no signal
1093 Device Issue 9 0.1 0.1 no signal
1094 Inappropriate Schedule Of Product Administration 17 0.1 0.1 no signal
1095 Device Leakage 4 0.1 0.1 no signal
1096 Product Dose Omission Issue 22 0.1 0.1 no signal
1097 Drug Dose Omission By Device 3 0.0 0.0 no signal