OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Pilocarpine Hydrochloride

214 flagged reaction(s) · 5,259 total co-reports · max PRR 44.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Vitreous Floaters 69 44.7 45.6 signal
2 Retinal Detachment 48 32.9 33.3 signal
3 Eye Pain 163 18.5 19.4 signal
4 Ocular Discomfort 30 17.3 17.5 signal
5 Eye Irritation 141 15.9 16.5 signal
6 Sputum Discoloured 20 13.3 13.4 signal
7 Intraocular Pressure Increased 26 12.7 12.8 signal
8 Ocular Hyperaemia 93 12.5 12.8 signal
9 Vasculitis 23 12.4 12.5 signal
10 Photophobia 33 11.1 11.2 signal
11 Intervertebral Disc Degeneration 16 10.8 10.8 signal
12 Body Temperature Decreased 17 10.7 10.8 signal
13 Visual Impairment 203 10.4 11.0 signal
14 Limb Injury 44 10.2 10.3 signal
15 Platelet Count Increased 21 10.1 10.1 signal
16 Vision Blurred 209 9.6 10.2 signal
17 Wound 42 9.5 9.6 signal
18 Glaucoma 29 9.4 9.5 signal
19 Haematocrit Decreased 28 8.8 8.9 signal
20 Dry Eye 63 8.2 8.3 signal
21 Autoimmune Disorder 12 7.9 7.9 signal
22 Pulmonary Congestion 16 7.6 7.6 signal
23 Eye Inflammation 11 7.3 7.3 signal
24 Sciatica 18 7.1 7.1 signal
25 Choking 22 7.1 7.1 signal
26 Sinus Disorder 22 7.0 7.0 signal
27 Poor Venous Access 11 6.7 6.7 signal
28 Transient Ischaemic Attack 36 6.7 6.7 signal
29 Dry Mouth 86 6.7 6.8 signal
30 Musculoskeletal Chest Pain 16 6.5 6.5 signal
31 Kidney Infection 20 6.4 6.4 signal
32 Lacrimation Increased 30 6.3 6.3 signal
33 Salivary Hypersecretion 10 6.3 6.3 signal
34 Seasonal Allergy 14 6.2 6.2 signal
35 Eye Discharge 10 6.1 6.2 signal
36 Increased Tendency To Bruise 9 6.1 6.1 signal
37 Productive Cough 46 6.1 6.2 signal
38 Impaired Driving Ability 11 6.1 6.1 signal
39 Therapeutic Response Shortened 30 5.9 6.0 signal
40 Dental Caries 10 5.7 5.7 signal
41 Generalised Oedema 11 5.6 5.6 signal
42 Infusion Related Reaction 59 5.6 5.7 signal
43 Coronary Artery Disease 27 5.5 5.6 signal
44 Blood Pressure Fluctuation 21 5.5 5.5 signal
45 Vitamin D Deficiency 8 5.1 5.2 signal
46 Ligament Sprain 8 5.1 5.1 signal
47 Inflammation 41 5.0 5.1 signal
48 Dermatitis Contact 9 5.0 5.0 signal
49 Emphysema 8 5.0 5.0 signal
50 Osteoporosis 32 4.9 4.9 signal
51 Rotator Cuff Syndrome 10 4.9 4.9 signal
52 Ear Pain 15 4.8 4.9 signal
53 C-reactive Protein Increased 28 4.8 4.9 signal
54 Oral Candidiasis 10 4.8 4.8 signal
55 Blood Pressure Systolic Increased 15 4.8 4.8 signal
56 Eye Disorder 25 4.8 4.8 signal
57 Iron Deficiency Anaemia 7 4.8 4.8 signal
58 Osteoarthritis 32 4.7 4.8 signal
59 Urinary Retention 25 4.7 4.7 signal
60 Pneumonitis 20 4.6 4.7 signal
61 Pharyngeal Swelling 7 4.6 4.6 signal
62 Hip Arthroplasty 11 4.5 4.6 signal
63 Red Blood Cell Sedimentation Rate Increased 8 4.5 4.5 signal
64 Osteopenia 11 4.5 4.5 signal
65 Visual Acuity Reduced 24 4.5 4.5 signal
66 Eye Infection 8 4.5 4.5 signal
67 Heart Rate Decreased 25 4.4 4.5 signal
68 Neuralgia 17 4.4 4.4 signal
69 Bacterial Infection 13 4.4 4.4 signal
70 Hiatus Hernia 9 4.3 4.4 signal
71 Hand Deformity 9 4.3 4.3 signal
72 Tooth Abscess 7 4.3 4.3 signal
73 Arthropathy 38 4.3 4.3 signal
74 Sleep Apnoea Syndrome 13 4.3 4.3 signal
75 Musculoskeletal Disorder 13 4.3 4.3 signal
76 Acute Myocardial Infarction 20 4.2 4.3 signal
77 Migraine 64 4.2 4.3 signal
78 Headache 420 4.2 4.7 signal
79 Gout 12 4.2 4.2 signal
80 Skin Laceration 7 4.1 4.1 signal
81 Limb Discomfort 20 4.0 4.1 signal
82 Pharyngitis 8 4.0 4.0 signal
83 Urinary Incontinence 19 4.0 4.0 signal
84 Lung Disorder 31 4.0 4.0 signal
85 Skin Disorder 21 4.0 4.0 signal
86 Musculoskeletal Stiffness 55 3.9 4.0 signal
87 Infusion Site Pain 8 3.9 3.9 signal
88 Tooth Disorder 14 3.9 3.9 signal
89 Herpes Zoster 36 3.9 4.0 signal
90 Hot Flush 47 3.9 3.9 signal
91 Eye Swelling 23 3.9 3.9 signal
92 Nodule 8 3.8 3.8 signal
93 Anorexia 8 3.8 3.8 signal
94 Oxygen Saturation Decreased 34 3.8 3.8 signal
95 Photosensitivity Reaction 10 3.8 3.8 signal
96 Pulmonary Mass 9 3.8 3.8 signal
97 Blood Alkaline Phosphatase Increased 15 3.8 3.8 signal
98 Ear Infection 16 3.8 3.8 signal
99 Blood Pressure Increased 91 3.7 3.8 signal
100 Body Temperature Increased 12 3.7 3.7 signal
101 Ear Discomfort 6 3.7 3.7 signal
102 Folliculitis 6 3.6 3.6 signal
103 Pulmonary Oedema 26 3.6 3.7 signal
104 Cardiac Failure Congestive 47 3.6 3.7 signal
105 Respiratory Tract Infection 15 3.6 3.6 signal
106 Pulmonary Fibrosis 11 3.6 3.6 signal
107 Heart Rate Irregular 13 3.6 3.6 signal
108 Carpal Tunnel Syndrome 8 3.6 3.6 signal
109 Blindness Unilateral 8 3.6 3.6 signal
110 Cold Sweat 10 3.6 3.6 signal
111 Therapeutic Product Effect Decreased 25 3.5 3.5 signal
112 Discomfort 34 3.5 3.5 signal
113 Urinary Tract Infection 95 3.5 3.6 signal
114 Synovitis 10 3.5 3.5 signal
115 Hyperthyroidism 8 3.5 3.5 signal
116 Product Packaging Quantity Issue 6 3.4 3.4 signal
117 Pulmonary Arterial Hypertension 8 3.4 3.4 signal
118 Blood Cholesterol Increased 25 3.4 3.4 signal
119 Cellulitis 27 3.4 3.4 signal
120 Bronchitis 39 3.3 3.3 signal
121 Eye Haemorrhage 7 3.3 3.3 signal
122 Therapeutic Product Effect Incomplete 37 3.3 3.3 signal
123 Musculoskeletal Discomfort 9 3.3 3.3 signal
124 Hyperhidrosis 67 3.3 3.3 signal
125 Uveitis 7 3.2 3.3 signal
126 Sinus Congestion 7 3.2 3.2 signal
127 Eye Pruritus 17 3.2 3.2 signal
128 Joint Injury 11 3.2 3.2 signal
129 Musculoskeletal Pain 27 3.2 3.2 signal
130 Fungal Infection 17 3.2 3.2 signal
131 Dyspnoea Exertional 19 3.2 3.2 signal
132 Respiratory Tract Congestion 8 3.2 3.2 signal
133 Sinusitis 51 3.1 3.1 signal
134 Localised Infection 12 3.1 3.1 signal
135 Spinal Operation 6 3.1 3.1 signal
136 Fibromyalgia 12 3.1 3.1 signal
137 Hypothermia 5 3.1 3.1 signal
138 Conjunctivitis 9 3.1 3.1 signal
139 Joint Swelling 59 3.1 3.1 signal
140 Burning Sensation 34 3.0 3.1 signal
141 Asthma 54 3.0 3.1 signal
142 Mydriasis 6 2.9 2.9 signal
143 Irritable Bowel Syndrome 10 2.9 2.9 signal
144 Therapeutic Response Decreased 28 2.9 2.9 signal
145 Pharyngitis Streptococcal 5 2.9 2.9 signal
146 Back Injury 5 2.9 2.9 signal
147 Chest Discomfort 47 2.9 2.9 signal
148 Interstitial Lung Disease 22 2.9 2.9 signal
149 Product Use Complaint 7 2.8 2.8 signal
150 Product Administration Error 9 2.8 2.8 signal
151 Rhinorrhoea 29 2.8 2.8 signal
152 Weight Increased 100 2.8 2.9 signal
153 Chromaturia 10 2.8 2.8 signal
154 Back Disorder 7 2.7 2.7 signal
155 Mucosal Inflammation 11 2.6 2.6 signal
156 Impaired Work Ability 9 2.6 2.6 signal
157 Cholestasis 8 2.6 2.6 signal
158 Knee Operation 4 2.6 2.6 no signal
159 Nasal Congestion 24 2.6 2.6 signal
160 Rheumatoid Arthritis 46 2.5 2.6 signal
161 Sneezing 9 2.5 2.5 signal
162 Spinal Fracture 8 2.5 2.5 signal
163 Procedural Pain 11 2.5 2.5 signal
164 Blindness 16 2.5 2.5 signal
165 Haemorrhage 41 2.5 2.5 signal
166 Poor Quality Product Administered 4 2.5 2.5 no signal
167 Knee Arthroplasty 8 2.4 2.4 signal
168 Hernia 7 2.3 2.3 no signal
169 Surgery 21 2.3 2.3 signal
170 Osteonecrosis Of Jaw 9 2.3 2.3 signal
171 Oral Discomfort 5 2.3 2.3 no signal
172 Disability 7 2.2 2.2 no signal
173 Upper Limb Fracture 7 2.2 2.2 no signal
174 Internal Haemorrhage 4 2.2 2.2 no signal
175 Systemic Lupus Erythematosus 12 2.1 2.1 signal
176 Skin Cancer 7 2.0 2.0 no signal
177 Myocardial Infarction 55 2.0 2.0 no signal
178 Affect Lability 3 1.9 1.9 no signal
179 Pneumocystis Jirovecii Pneumonia 3 1.9 1.9 no signal
180 Ovarian Cyst 3 1.9 1.9 no signal
181 Bone Marrow Failure 6 1.8 1.8 no signal
182 Multiple Sclerosis 14 1.8 1.8 no signal
183 Hereditary Angioedema 3 1.8 1.8 no signal
184 Injection Site Haematoma 4 1.7 1.7 no signal
185 Drug Dispensing Error 4 1.6 1.6 no signal
186 Madarosis 3 1.6 1.6 no signal
187 Psoriatic Arthropathy 10 1.6 1.6 no signal
188 Therapy Interrupted 17 1.5 1.5 no signal
189 Application Site Irritation 3 1.5 1.5 no signal
190 Tooth Loss 5 1.5 1.5 no signal
191 Drug Effect Decreased 13 1.5 1.5 no signal
192 Injection Site Irritation 3 1.5 1.5 no signal
193 Injection Site Reaction 16 1.5 1.5 no signal
194 Acne 17 1.4 1.4 no signal
195 Drug Toxicity 3 1.4 1.4 no signal
196 Wrong Technique In Drug Usage Process 7 1.2 1.2 no signal
197 Wrong Technique In Product Usage Process 38 1.2 1.2 no signal
198 Injection Site Haemorrhage 14 1.1 1.1 no signal
199 Tardive Dyskinesia 5 1.1 1.1 no signal
200 Multiple Sclerosis Relapse 12 1.1 1.1 no signal
201 Complication Of Device Insertion 3 1.0 1.0 no signal
202 Psoriasis 21 1.0 1.0 no signal
203 Skin Burning Sensation 11 1.0 1.0 no signal
204 Injection Site Erythema 19 1.0 1.0 no signal
205 Injection Site Warmth 3 0.9 0.9 no signal
206 Injection Site Pain 42 0.9 0.9 no signal
207 Injection Site Pruritus 9 0.8 0.8 no signal
208 Injection Site Swelling 10 0.8 0.8 no signal
209 Injection Site Bruising 10 0.8 0.8 no signal
210 Product Complaint 3 0.8 0.8 no signal
211 Extrapyramidal Disorder 3 0.7 0.7 no signal
212 Application Site Erythema 3 0.7 0.7 no signal
213 Breast Cancer Female 3 0.7 0.7 no signal
214 Product Adhesion Issue 3 0.5 0.5 no signal