Drug

Pioglitazone Hydrochloride

53 flagged reaction(s) · 1,174 total co-reports · max PRR 64.2

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Vasculitis	44	64.2	66.5	signal
2	Arteriosclerosis	35	63.1	64.9	signal
3	Full Blood Count Abnormal	34	54.8	56.3	signal
4	Obstructive Airways Disorder	32	48.7	50.0	signal
5	Nodule	36	46.8	48.2	signal
6	Sleep Disorder Due To A General Medical Condition	43	45.2	46.7	signal
7	Pulmonary Fibrosis	32	28.4	29.1	signal
8	Clostridium Difficile Colitis	14	22.4	22.6	signal
9	Haemoptysis	35	21.2	21.8	signal
10	Hypoglycaemia	60	21.0	22.0	signal
11	Hypothyroidism	35	18.6	19.1	signal
12	Cardiomegaly	13	17.8	17.9	signal
13	Diabetes Mellitus Inadequate Control	18	17.2	17.5	signal
14	Hypoxia	35	16.9	17.4	signal
15	Glycosylated Haemoglobin Increased	22	14.8	15.1	signal
16	Productive Cough	38	13.6	14.0	signal
17	Diabetic Ketoacidosis	19	13.4	13.6	signal
18	Lactic Acidosis	25	13.2	13.5	signal
19	Loss Of Personal Independence In Daily Activities	37	13.2	13.6	signal
20	Wheezing	46	13.2	13.6	signal
21	Poor Venous Access	8	13.1	13.2	signal
22	Haemorrhoids	14	12.1	12.3	signal
23	Hyperglycaemia	26	12.1	12.4	signal
24	Body Temperature Decreased	7	11.9	12.0	signal
25	Lung Disorder	34	11.8	12.1	signal
26	Therapeutic Product Effect Incomplete	47	11.3	11.7	signal
27	Blood Glucose Abnormal	12	11.0	11.1	signal
28	Thrombosis	51	10.7	11.1	signal
29	Inflammatory Bowel Disease	6	10.3	10.4	signal
30	Hypercalcaemia	7	9.6	9.7	signal
31	Hyperkalaemia	19	9.2	9.4	signal
32	Pancreatitis Acute	11	8.4	8.4	signal
33	Renal Failure Acute	20	7.9	8.0	signal
34	Cardiac Failure	37	7.8	8.0	signal
35	Blood Pressure Systolic Increased	9	7.8	7.8	signal
36	Cerebral Infarction	11	7.6	7.7	signal
37	Acute Myocardial Infarction	13	7.4	7.5	signal
38	Hepatic Function Abnormal	16	7.3	7.4	signal
39	Altered State Of Consciousness	9	7.1	7.1	signal
40	Transient Ischaemic Attack	14	7.0	7.1	signal
41	Skin Exfoliation	29	5.9	6.0	signal
42	Blood Glucose Decreased	15	5.3	5.3	signal
43	Bladder Cancer	17	4.8	4.9	signal
44	Blood Glucose Increased	52	4.7	4.8	signal
45	Blood Glucose Fluctuation	3	4.6	4.6	signal
46	Osteonecrosis Of Jaw	6	4.1	4.1	signal
47	Cytomegalovirus Infection	4	4.1	4.1	signal
48	Sopor	3	3.8	3.8	no signal
49	Pancreatic Carcinoma	6	3.5	3.5	signal
50	Application Site Erythema	4	2.6	2.6	no signal
51	Wrong Technique In Drug Usage Process	5	2.3	2.3	no signal
52	Hepatic Cancer	3	2.1	2.1	no signal
53	Gynaecomastia	3	1.6	1.6	no signal