Drug

Polymyxin B Sulfate

56 flagged reaction(s) · 2,887 total co-reports · max PRR 201.1

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Macular Degeneration	176	201.1	226.5	signal
2	Respiratory Tract Infection	165	85.8	95.8	signal
3	Oedema	186	46.3	52.4	signal
4	Vaginal Discharge	33	44.2	45.1	signal
5	Paraesthesia Oral	46	43.1	44.3	signal
6	Oral Candidiasis	36	37.2	38.1	signal
7	Wheezing	157	35.7	39.6	signal
8	Disseminated Intravascular Coagulation	28	26.7	27.1	signal
9	Asthma	185	22.2	25.0	signal
10	Drug Resistance	41	21.4	22.0	signal
11	Procedural Pain	40	19.4	19.9	signal
12	Drug Hypersensitivity	250	17.3	20.4	signal
13	Frequent Bowel Movements	34	17.0	17.3	signal
14	Thrombotic Microangiopathy	12	16.6	16.8	signal
15	Hepatic Function Abnormal	39	14.1	14.5	signal
16	Cytomegalovirus Infection	17	13.7	13.9	signal
17	Nephropathy Toxic	11	13.3	13.3	signal
18	Chest Pain	180	13.0	14.6	signal
19	Multiple Organ Dysfunction Syndrome	27	13.0	13.2	signal
20	Colitis	35	12.5	12.7	signal
21	Neurotoxicity	14	10.8	10.9	signal
22	Rectal Haemorrhage	34	10.6	10.8	signal
23	Colitis Ulcerative	34	10.2	10.4	signal
24	Clostridium Difficile Colitis	8	10.1	10.2	signal
25	Acute Respiratory Distress Syndrome	13	9.9	9.9	signal
26	Pneumonia	231	9.6	11.1	signal
27	Infusion Related Reaction	47	9.6	9.8	signal
28	Bacterial Infection	13	9.4	9.5	signal
29	Haematochezia	36	8.8	9.0	signal
30	Septic Shock	28	8.7	8.8	signal
31	Drug Ineffective For Unapproved Indication	36	8.7	8.8	signal
32	Blood Lactate Dehydrogenase Increased	10	8.4	8.5	signal
33	Eye Infection	7	8.4	8.4	signal
34	Febrile Neutropenia	41	8.3	8.5	signal
35	Therapeutic Product Effect Incomplete	42	8.0	8.2	signal
36	Emphysema	6	8.0	8.0	signal
37	Bone Marrow Failure	12	7.9	7.9	signal
38	Pneumothorax	9	7.6	7.7	signal
39	Cough	157	7.5	8.3	signal
40	Deformity	5	7.2	7.2	signal
41	Malaise	231	7.1	8.1	signal
42	Therapeutic Product Effect Decreased	22	6.7	6.7	signal
43	Conjunctivitis	9	6.6	6.6	signal
44	Treatment Failure	38	6.2	6.3	signal
45	Gamma-glutamyltransferase Increased	10	6.1	6.1	signal
46	Foot Deformity	5	6.0	6.1	signal
47	Joint Range Of Motion Decreased	6	6.0	6.0	signal
48	Neutrophil Count Decreased	18	6.0	6.0	signal
49	Altered State Of Consciousness	9	5.6	5.6	signal
50	Eosinophilia	7	5.4	5.4	signal
51	Toxic Epidermal Necrolysis	6	5.3	5.4	signal
52	Acute Myeloid Leukaemia	5	4.3	4.3	signal
53	Rheumatoid Arthritis	28	3.3	3.4	signal
54	Tuberculosis	3	3.1	3.1	no signal
55	Premature Delivery	3	2.5	2.5	no signal
56	Myelosuppression	6	2.4	2.4	no signal