OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Propafenone

225 flagged reaction(s) · 6,416 total co-reports · max PRR 27.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Sinus Bradycardia 54 27.9 28.3 signal
2 Ventricular Tachycardia 80 24.2 24.6 signal
3 Supraventricular Tachycardia 37 19.3 19.5 signal
4 Atrial Fibrillation 354 18.1 19.7 signal
5 Subarachnoid Haemorrhage 34 16.6 16.8 signal
6 Bradycardia 170 16.0 16.6 signal
7 Generalised Tonic-clonic Seizure 49 15.0 15.1 signal
8 Arrhythmia 139 14.6 15.1 signal
9 Heart Rate Irregular 63 13.8 14.0 signal
10 Drug Level Increased 40 12.1 12.2 signal
11 Ventricular Fibrillation 26 11.7 11.7 signal
12 Cardiogenic Shock 31 10.8 10.9 signal
13 Basal Cell Carcinoma 32 10.2 10.3 signal
14 Drug Interaction 325 10.2 11.0 signal
15 Ventricular Extrasystoles 21 10.1 10.1 signal
16 Electrocardiogram Qt Prolonged 67 9.3 9.4 signal
17 Myocardial Ischaemia 20 8.7 8.7 signal
18 Metabolic Acidosis 55 8.7 8.8 signal
19 Upper Gastrointestinal Haemorrhage 29 8.6 8.6 signal
20 Squamous Cell Carcinoma 16 8.5 8.5 signal
21 Cardiac Arrest 129 7.8 8.0 signal
22 Haematuria 51 7.4 7.5 signal
23 Ischaemic Stroke 26 7.3 7.3 signal
24 Toxicity To Various Agents 238 7.1 7.4 signal
25 Completed Suicide 119 7.1 7.2 signal
26 International Normalised Ratio Increased 39 6.8 6.8 signal
27 Scratch 14 6.7 6.8 signal
28 Hypertensive Crisis 15 6.7 6.7 signal
29 Altered State Of Consciousness 28 6.5 6.5 signal
30 Eye Haemorrhage 17 6.3 6.4 signal
31 Mitral Valve Incompetence 14 6.2 6.2 signal
32 Drug-induced Liver Injury 37 6.0 6.0 signal
33 Presyncope 29 6.0 6.0 signal
34 Shock 26 5.7 5.7 signal
35 Mental Status Changes 30 5.4 5.4 signal
36 Obstructive Airways Disorder 12 5.4 5.4 signal
37 Transient Ischaemic Attack 36 5.3 5.3 signal
38 Toxic Epidermal Necrolysis 16 5.3 5.3 signal
39 Intentional Overdose 67 5.2 5.3 signal
40 Syncope 105 5.2 5.3 signal
41 Coagulopathy 17 5.1 5.1 signal
42 Cardiomyopathy 15 5.1 5.1 signal
43 Gastrointestinal Haemorrhage 85 5.0 5.1 signal
44 Petechiae 10 4.8 4.8 signal
45 Rhabdomyolysis 40 4.8 4.8 signal
46 Gout 17 4.7 4.7 signal
47 Pulmonary Hypertension 19 4.5 4.5 signal
48 Heart Rate Decreased 32 4.5 4.5 signal
49 Palpitations 106 4.5 4.6 signal
50 Cardio-respiratory Arrest 38 4.5 4.5 signal
51 Hypothermia 9 4.4 4.4 signal
52 Inappropriate Antidiuretic Hormone Secretion 9 4.4 4.4 signal
53 Hypotension 172 4.3 4.4 signal
54 Epistaxis 64 4.3 4.3 signal
55 Haematochezia 47 4.3 4.3 signal
56 Clostridium Difficile Colitis 9 4.2 4.2 signal
57 Sinus Tachycardia 12 4.2 4.2 signal
58 Rectal Haemorrhage 35 4.0 4.1 signal
59 Loss Of Consciousness 104 4.0 4.1 signal
60 Ligament Sprain 8 4.0 4.0 signal
61 Diplopia 21 4.0 4.0 signal
62 Blood Pressure Abnormal 16 4.0 4.0 signal
63 Suicide Attempt 49 4.0 4.1 signal
64 Haemorrhage Intracranial 12 4.0 4.0 signal
65 Brain Oedema 10 3.9 4.0 signal
66 Internal Haemorrhage 9 3.9 3.9 signal
67 Depressed Level Of Consciousness 31 3.9 3.9 signal
68 Coma 37 3.9 3.9 signal
69 Lymphoma 12 3.9 3.9 signal
70 Post Procedural Haemorrhage 9 3.8 3.8 signal
71 Pallor 21 3.8 3.9 signal
72 Spinal Pain 9 3.8 3.8 signal
73 Subdural Haematoma 11 3.8 3.8 signal
74 Cyanosis 12 3.8 3.8 signal
75 Hyperthyroidism 11 3.8 3.8 signal
76 Hypokinesia 11 3.8 3.8 signal
77 Acute Kidney Injury 114 3.7 3.8 signal
78 Hyperkalaemia 26 3.7 3.7 signal
79 Accidental Overdose 27 3.7 3.7 signal
80 Tachypnoea 10 3.7 3.7 signal
81 Hepatotoxicity 16 3.6 3.6 signal
82 Haematocrit Decreased 14 3.5 3.5 signal
83 Pericardial Effusion 16 3.5 3.5 signal
84 Hiatus Hernia 9 3.5 3.5 signal
85 Seizure 79 3.4 3.5 signal
86 Respiratory Distress 19 3.4 3.4 signal
87 Product Prescribing Issue 14 3.4 3.4 signal
88 Tachycardia 61 3.4 3.5 signal
89 Eyelid Oedema 8 3.4 3.4 signal
90 Sleep Apnoea Syndrome 13 3.4 3.4 signal
91 Product Taste Abnormal 9 3.3 3.3 signal
92 Chromaturia 15 3.3 3.3 signal
93 Premature Baby 20 3.3 3.3 signal
94 Glomerular Filtration Rate Decreased 8 3.3 3.3 signal
95 Hip Fracture 21 3.3 3.3 signal
96 Haematoma 17 3.3 3.3 signal
97 Disseminated Intravascular Coagulation 9 3.2 3.2 signal
98 Hypocalcaemia 12 3.2 3.2 signal
99 Orthostatic Hypotension 11 3.1 3.1 signal
100 Bronchospasm 9 3.1 3.1 signal
101 Angina Pectoris 18 3.1 3.1 signal
102 Balance Disorder 54 3.1 3.1 signal
103 Pulmonary Arterial Hypertension 9 3.1 3.1 signal
104 Colitis 23 3.0 3.1 signal
105 Inability To Afford Medication 6 3.0 3.0 signal
106 Multiple Organ Dysfunction Syndrome 17 3.0 3.0 signal
107 Hepatomegaly 6 3.0 3.0 signal
108 Body Temperature Decreased 6 3.0 3.0 signal
109 Hypothyroidism 19 3.0 3.0 signal
110 Heart Rate Increased 58 2.9 2.9 signal
111 Cardiac Failure 47 2.9 2.9 signal
112 Blood Sodium Decreased 11 2.9 2.9 signal
113 Coronary Artery Occlusion 8 2.9 2.9 signal
114 Ejection Fraction Decreased 9 2.9 2.9 signal
115 Blood Pressure Decreased 38 2.9 2.9 signal
116 Cold Sweat 10 2.8 2.8 signal
117 Muscle Twitching 13 2.8 2.8 signal
118 Cognitive Disorder 26 2.8 2.8 signal
119 Body Height Decreased 6 2.8 2.8 signal
120 Spinal Fracture 11 2.8 2.8 signal
121 Increased Tendency To Bruise 5 2.7 2.7 no signal
122 Abnormal Dreams 15 2.7 2.7 signal
123 Product Substitution Issue 31 2.7 2.7 signal
124 Head Injury 17 2.7 2.7 signal
125 Speech Disorder 28 2.7 2.7 signal
126 Grand Mal Convulsion 5 2.7 2.7 no signal
127 Dyspnoea Exertional 20 2.7 2.7 signal
128 Therapy Partial Responder 8 2.6 2.7 signal
129 Dizziness 264 2.6 2.8 signal
130 Anhedonia 14 2.6 2.6 signal
131 Extrapyramidal Disorder 13 2.6 2.6 signal
132 Drug Prescribing Error 10 2.6 2.6 signal
133 Abdominal Pain Lower 13 2.6 2.6 signal
134 Splenomegaly 6 2.6 2.6 signal
135 Nervous System Disorder 16 2.5 2.6 signal
136 Lung Infection 8 2.5 2.5 signal
137 Unresponsive To Stimuli 13 2.5 2.5 signal
138 Medication Error 28 2.5 2.5 signal
139 Disease Recurrence 24 2.5 2.5 signal
140 Lymphopenia 7 2.5 2.5 signal
141 Contraindicated Product Administered 15 2.5 2.5 signal
142 Blood Pressure Increased 76 2.5 2.5 signal
143 Toxic Skin Eruption 5 2.5 2.5 no signal
144 Cyst 6 2.4 2.4 no signal
145 Pain Of Skin 13 2.4 2.4 signal
146 Muscle Atrophy 6 2.4 2.4 no signal
147 Cytokine Release Syndrome 9 2.4 2.4 signal
148 Joint Injury 10 2.3 2.3 signal
149 Renal Injury 14 2.3 2.3 signal
150 Renal Failure Acute 20 2.3 2.3 signal
151 Back Injury 5 2.3 2.3 no signal
152 Gastric Disorder 16 2.3 2.3 signal
153 Blood Count Abnormal 7 2.3 2.3 no signal
154 Adverse Reaction 6 2.3 2.3 no signal
155 Drug Dispensing Error 7 2.3 2.3 no signal
156 Emotional Disorder 14 2.2 2.3 signal
157 Rash Maculo-papular 10 2.2 2.3 signal
158 Sinus Congestion 6 2.2 2.2 no signal
159 Acute Myocardial Infarction 13 2.2 2.2 signal
160 Abscess 7 2.2 2.2 no signal
161 Hallucination, Visual 9 2.1 2.1 signal
162 Diarrhoea Haemorrhagic 4 2.1 2.1 no signal
163 Overdose 92 2.1 2.1 signal
164 Lip Swelling 14 2.1 2.1 signal
165 Cerebral Haemorrhage 15 2.1 2.1 signal
166 Skin Cancer 9 2.1 2.1 signal
167 Hypoglycaemia 20 2.1 2.1 signal
168 Melaena 9 2.0 2.0 no signal
169 Jaundice 11 2.0 2.0 signal
170 Fluid Overload 6 2.0 2.0 no signal
171 Salivary Hypersecretion 4 2.0 2.0 no signal
172 Respiratory Arrest 11 2.0 2.0 no signal
173 Cardiac Failure Congestive 31 1.9 1.9 no signal
174 Herpes Zoster 22 1.9 1.9 no signal
175 Transfusion 4 1.9 1.9 no signal
176 Haemorrhage 39 1.9 1.9 no signal
177 Malignant Melanoma 5 1.9 1.9 no signal
178 Hair Texture Abnormal 5 1.8 1.8 no signal
179 Cerebral Infarction 9 1.8 1.8 no signal
180 Acute Hepatic Failure 5 1.8 1.8 no signal
181 Cholestasis 7 1.8 1.8 no signal
182 Dysgeusia 27 1.8 1.8 no signal
183 Status Epilepticus 4 1.8 1.8 no signal
184 Cardiovascular Disorder 9 1.8 1.8 no signal
185 Skin Haemorrhage 5 1.7 1.7 no signal
186 Neurotoxicity 6 1.7 1.7 no signal
187 Gastric Haemorrhage 4 1.7 1.7 no signal
188 Madarosis 4 1.7 1.7 no signal
189 Cerebrovascular Accident 58 1.7 1.7 no signal
190 Intentional Product Misuse 29 1.7 1.7 no signal
191 Product Quality Issue 44 1.6 1.6 no signal
192 Brain Neoplasm 3 1.6 1.6 no signal
193 Tendon Rupture 4 1.6 1.6 no signal
194 Poisoning Deliberate 3 1.6 1.6 no signal
195 Foetal Exposure During Pregnancy 26 1.6 1.6 no signal
196 Cardiac Disorder 30 1.6 1.6 no signal
197 Poisoning 4 1.6 1.6 no signal
198 Eructation 6 1.6 1.6 no signal
199 Intraocular Pressure Increased 4 1.6 1.6 no signal
200 Inappropriate Schedule Of Drug Administration 22 1.5 1.5 no signal
201 Sopor 4 1.5 1.5 no signal
202 Intentional Self-injury 6 1.5 1.5 no signal
203 Skin Burning Sensation 20 1.4 1.4 no signal
204 Convulsion 16 1.4 1.4 no signal
205 Wrong Technique In Drug Usage Process 10 1.4 1.4 no signal
206 Expired Product Administered 9 1.4 1.4 no signal
207 Drug Abuse 21 1.3 1.3 no signal
208 Product Physical Issue 5 1.3 1.3 no signal
209 Activities Of Daily Living Impaired 5 1.2 1.2 no signal
210 Hair Colour Changes 3 1.2 1.2 no signal
211 Circumstance Or Information Capable Of Leading To Medication Error 8 1.2 1.2 no signal
212 Vaginal Haemorrhage 10 1.2 1.2 no signal
213 Drug Effect Incomplete 8 1.1 1.1 no signal
214 Plasma Cell Myeloma 8 1.0 1.0 no signal
215 Injection Site Haemorrhage 16 1.0 1.0 no signal
216 Intentional Drug Misuse 4 0.9 0.9 no signal
217 Premature Delivery 3 0.9 0.9 no signal
218 Drug Dose Omission 31 0.9 0.9 no signal
219 Application Site Pain 4 0.9 0.9 no signal
220 Product Preparation Error 3 0.7 0.7 no signal
221 Application Site Pruritus 3 0.7 0.7 no signal
222 Application Site Erythema 3 0.6 0.6 no signal
223 Device Breakage 3 0.4 0.4 no signal
224 Prostate Cancer 6 0.4 0.4 no signal
225 Bladder Cancer 3 0.3 0.3 no signal