Drug

Propylthiouracil

66 flagged reaction(s) · 1,501 total co-reports · max PRR 98.5

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Hyperthyroidism	138	98.5	105.5	signal
2	Cardiogenic Shock	50	36.0	36.8	signal
3	Acute Hepatic Failure	46	34.7	35.5	signal
4	Agranulocytosis	60	33.3	34.3	signal
5	Vasculitis	32	28.1	28.6	signal
6	Sinus Bradycardia	16	16.9	17.0	signal
7	Premature Baby	49	16.6	17.0	signal
8	Hepatic Encephalopathy	15	16.5	16.6	signal
9	Hepatotoxicity	35	16.2	16.4	signal
10	Premature Delivery	25	16.0	16.2	signal
11	Hypothyroidism	47	15.1	15.4	signal
12	Foetal Exposure During Pregnancy	117	14.8	15.6	signal
13	Circulatory Collapse	24	14.4	14.5	signal
14	Exposure During Pregnancy	85	14.0	14.6	signal
15	Drug-induced Liver Injury	38	12.6	12.8	signal
16	Caesarean Section	14	12.2	12.3	signal
17	Multiple Organ Dysfunction Syndrome	33	12.1	12.3	signal
18	Hyperbilirubinaemia	11	10.9	11.0	signal
19	Renal Tubular Necrosis	10	10.4	10.5	signal
20	Drug Reaction With Eosinophilia And Systemic Symptoms	25	10.0	10.1	signal
21	Cardiomegaly	12	9.9	10.0	signal
22	Maternal Exposure During Pregnancy	76	8.8	9.1	signal
23	Hepatitis	22	8.8	8.9	signal
24	Cholestasis	16	8.6	8.6	signal
25	Mitral Valve Incompetence	9	8.1	8.2	signal
26	Ventricular Tachycardia	13	8.0	8.1	signal
27	Hepatic Failure	23	7.8	7.9	signal
28	Blood Thyroid Stimulating Hormone Increased	7	7.8	7.8	signal
29	Eosinophilia	13	7.6	7.7	signal
30	Drug Exposure During Pregnancy	25	7.4	7.5	signal
31	Rhabdomyolysis	30	7.4	7.5	signal
32	Disseminated Intravascular Coagulation	10	7.2	7.3	signal
33	Sinus Tachycardia	10	7.2	7.3	signal
34	Cardiac Arrest	55	6.8	7.0	signal
35	Liver Injury	16	6.8	6.8	signal
36	Drug Toxicity	9	6.7	6.7	signal
37	Thyroid Disorder	10	6.6	6.7	signal
38	Brain Oedema	8	6.5	6.5	signal
39	Jaundice	17	6.4	6.5	signal
40	Product Physical Issue	12	6.2	6.2	signal
41	Adrenal Insufficiency	7	6.0	6.0	signal
42	International Normalised Ratio Increased	16	5.7	5.7	signal
43	Nephropathy	5	5.5	5.5	signal
44	Cardio-respiratory Arrest	22	5.3	5.4	signal
45	Treatment Noncompliance	27	5.1	5.1	signal
46	Toxic Skin Eruption	5	5.1	5.1	signal
47	Temperature Intolerance	5	5.0	5.0	signal
48	Red Blood Cell Sedimentation Rate Increased	5	4.6	4.6	signal
49	Drug Ineffective For Unapproved Indication	24	4.4	4.4	signal
50	Abortion Spontaneous	17	4.3	4.4	signal
51	Anorexia	5	3.9	3.9	signal
52	Cardiac Failure Congestive	30	3.8	3.8	signal
53	Cerebral Haemorrhage	13	3.7	3.7	signal
54	Myocarditis	4	3.6	3.6	signal
55	Rebound Effect	4	3.6	3.6	signal
56	Drug Resistance	9	3.6	3.6	signal
57	Hepatic Cytolysis	4	3.3	3.4	signal
58	No Therapeutic Response	4	3.3	3.3	signal
59	Abortion Induced	3	3.3	3.3	no signal
60	Hepatocellular Injury	4	2.9	2.9	no signal
61	Pregnancy	5	2.5	2.5	no signal
62	Product Taste Abnormal	3	2.3	2.3	no signal
63	Drug Dispensing Error	3	2.0	2.0	no signal
64	Application Site Pruritus	3	1.4	1.4	no signal
65	Intentional Overdose	8	1.3	1.3	no signal
66	Pharmaceutical Product Complaint	3	1.2	1.2	no signal